Publication Cover
Stress
The International Journal on the Biology of Stress
Volume 7, 2004 - Issue 2
73
Views
18
CrossRef citations to date
0
Altmetric
Original Article

Fos Expression in CRF-containing Neurons in the Rat Paraventricular Nucleus after Central Administration of Neuromedin U

, , , , , & show all
Pages 109-112 | Received 10 Nov 2003, Accepted 25 May 2004, Published online: 07 Jul 2009

References

  • Ballesta, J., Carlei, F., Bishop, A.E., Steel, J.H., Gibson, S.J., Fahey, M., Hennessey, R., Domin, J., Bloom, S.R. and Polak, J.M. (1988) Occurrence and developmental pattern of neuromedin U-immunoreactive nerves in the gastrointestinal tract and brain of the rat, Neuroscience 25, 797–816.
  • Brown, D.R. and Quito, F.L. (1988) Neuromedin U octapeptide alters ion transport in porcine jejunum, Eur. J. Pharmacol. 155, 159–162.
  • Cai, X.J., Widdowson, P.S., Harrold, J., Wilson, S. and Buckingham, R.E. (1999) Hypothalamic orexin expression: modulation by blood glucose and feeding, Arch. Diabetes 48, 2132–2137.
  • Chu, C., Jin, Q., Kunitake, T., Kato, K., Nabekura, T., Nakazato, M., Kangawa, K. and Kannan, H. (2002) Cardiovascular actions of central neuromedin U in conscious rats, Regul. Pept. 105, 29–34.
  • Domin, J., Ghatei, M.A., Chohan, P. and Bloom, S.R. (1986) Characterization of neuromedin U like immunoreactivity in rat, porcine, guinea-pig and human tissue extracts using a specific radioimmunoassay, Biochem. Biophys. Res. Commun. 140, 1127–1134.
  • Fujii, R., Hosoya, M., Fukusumi, S., Kawamata, Y., Habata, Y., Hinuma, S., Onda, H., Nishimura, O. and Fujino, M. (2000) Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3, J. Biol. Chem. 275, 21068–21074.
  • Hanada, R., Nakazato, M., Murakami, N., Sakihara, S., Yoshimatsu, H., Toshinai, K., Hanada, T., Suda, T., Kangawa, K., Matsukura, S. and Sakata, T. (2001) A role for neuromedin U in stress response, Biochem. Biophys. Res. Commun. 289, 225–228.
  • Honzawa, M., Sudoh, T., Minamino, N., Tohyama, M. and Matsuo, H. (1987) Topographic localization of neuromedin U-like structures in the rat brain: an immunohistochemical study, Neuroscience 23, 1103–1122.
  • Howard, A.D., Wang, R., Pong, S.S., Mellin, T.N., Strack, A., Guan, X.M., Zeng, Z., Williams, D.L. Jr, Feighnr, S.D., Nunes, C.N., Murphy, B., Stair, J.N., Yu, H., Jiang, Q., Clements, M.K., Tan, C.P., McKee, K.K., Hreniuk, D.L., McDonald, T.P., Lynch, K.R., Evans, J.F., Austin, C.P., Caskey, C.T., Van der Ploeg, L.H. and Liu, Q. (2000) Identification of receptors for neuromedin U and its role in feeding, Nature 406, 70–74.
  • Ivanov, T.R., Lawrence, C.B., Stanley, P.J. and Luckman, S.M. (2002) Evaluation of neuromedin U actions in energy homeostasis and pituitary function, Endocrinology 143, 3813–3821.
  • Kojima, M., Haruno, R., Nakazato, M., Date, Y., Murakami, N., Hanada, R., Matsuo, H. and Kangawa, K. (2000) Purification and identification of neruromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3), Biochem. Biophys. Res. Commun. 276, 435–438.
  • Malendowicz, L.K., Nussdorfer, G.G., Markowska, A., Tortorella, C., Nowak, M. and Warchol, J.B. (1994) Effects of neuromedin U (NMU) -8 on the rat hypothalamo-pituitary-adrenal axis. Evidence of a direct effect of NMU-8 on the adrenal gland, Neuropeptides 26, 47–53.
  • Minamino, N., Kangawa, K. and Matsuo, H. (1985) Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord, Biochem. Biophys. Res. Commun. 130, 1078–1085.
  • Nakazato, M., Hanada, R., Murakami, N., Date, Y., Mondal, M.S., Kojima, M., Yoshimatsu, H., Kangawa, K. and Matsukura, S. (2000) Central effects of neuromedin U in the regulation of energy homeostasis, Biochem. Biophys. Res. Commun. 277, 191–194.
  • Niimi, M., Murao, K. and Taminato, T. (2001) Central administration of neuromedin U activates neurons in ventrobasal hypothalamus and brainstem, Endocrine 16, 201–206.
  • Ozaki, Y., Onaka, T., Nakazato, M., Saito, J., Kanemoto, K., Matsumoto, T. and Ueta, Y. (2002) Centrally administered neuromedin U activates neurosecretion and induction of c-fos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat, Endocrinology 143, 4320–4329.
  • Palkovits, M., Brownstein, M.J. and Vale, W. (1985) Distribution of corticotropin-releasing factor in rat brain, Fed. Proc. 44, 215–219.
  • Paxinos, G. and Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd Ed. (Academic Press, Sydney).
  • Qiu, D.L., Chu, C.P., Shirasaka, T., Nabekura, T., Kunitake, T., Kato, K., Nakazato, M., Katoh, T. and Kannan, H. (2003) Neuromedin U depolarizes rat hypothalamic paraventricular nucleus neurons in vitro by enhanced IH channel activity, J. Neurophysiol. 90, 843–850.
  • Rokkaku, K., Onaka, T., Okada, N., Ideno, J., Kawakami, A., Honda, K., Yada, T. and Ishibashi, S. (2003) Neuromedin U facilitates oxytocin release from the pituitary via b adrenoceptors, Neuroreport 14, 1997–2000.
  • Sagar, S.M., Sharp, F.R. and Curran, T. (1988) Expression of c-fos protein in brain: metabolic mapping at the cellular level, Science 240, 1328–1331.
  • Swanson, L.W., Sawchenko, P.E., Rivier, J. and Vale, W.W. (1983) Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study, Neuroendocrinology 36, 165–186.
  • Szekeres, P.G., Muir, A.I., Spinage, L.D., Miller, J.E., Butler, S.I., Smith, A., Rennie, G.I., Murdock, P.R., Fitzgerald, L.R., Wu, H.I., McMillan, L.J., Guerrera, S., Vawter, L., Elshourbagy, N.A., Mooney, J.L., Bergsma, D.J., Wilson, S. and Chambers, J.K. (2000) Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3, J. Biol. Chem. 275, 20247–20250.
  • Wren, A.M., Small, C.J., Abbott, C.R., Jethwa, P.H., Kennedy, A.R., Murphy, K.G., Stanley, S.A., Zollner, A.N., Ghatei, M.A. and Bloom, S.R. (2002) Hypothalamic actions of neuromedin U, Endocrinology 143, 4227–4234.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.