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Articles

Computational modelling and analysis of mechanical conditions on cell locomotion and cell–cell interaction

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Pages 678-693 | Received 08 May 2012, Accepted 07 Jul 2012, Published online: 08 Aug 2012

References

  • AkiyamaSK, YamadaKM. 1985. The interaction of plasma fibronectin with fibroblastic cells in suspension. J Biol Chem. 260:4492–4500.
  • AndujarMB, MelinM, GuerretS, GrimaudJA. 1992. Cell migration influences collagen gel contraction. J Submicrosc Cytol Pathol. 24:145–154.
  • BehestiH, MarinoS. 2009. Cerebellar granule cells: insights into proliferation, differentiation, and role in medulloblastoma pathogenesis. J Appl Physiol. 41:435–445.
  • BershadskyAD, BalabanNQ, GeigerB. 2003. Adhesion-dependent cell mechanosensitivity. Annu Rev Cell Dev Biol. 19:677–695.
  • Borau C, Doweidar MH, Garcia-Aznar JM. 2010. Modeling of cell migration and mechano-sensing in 3d. 17th Congress of the European Society of Biomechanics. Edinburgh, UK.
  • BorauC, KammRD, García-AznarJM. 2011. Mechano-sensing and cell migration: a 3D model approach. J Phys Biol. 8:1078–1088.
  • BroflandGW, WiebeCJ. 2004. Mechanical effects of cell anisotropy on epithelia. Comput Methods Biomech Biomed Eng. 7:91–99.
  • BroflandGW, ViensD, VeldhuisJH. 2007. A new cell-based FE model for the mechanics of embryonic epithelia. Comput Methods Biomech Biomed Eng. 10:121–128.
  • BuxboimA, IvanovskaIL, DischerDE. 2010a. Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?J Cell Sci. 123:297–308.
  • BuxboimA, RajagopalK, BrownAEX, DischerDE. 2010b. How deeply cells feel: methods for thin gells. J Phys Condens Matter. 22(19):194116(10pp).
  • ChiquetM, GelmanL, LutzR, MaierS. 2009. Wound healing: aiming for perfect skin regeneration. Biochim Biophys Acta J. 1973:911–920.
  • DaltonBA, WalboomersXF, DziegielewskiM, EvansMDM, TaylorS, JansenJA, SteeleJG. 2001. Modulation of epithelial tissue and cell migration by microgrooves. Phil Trans Roy Soc London. 56:195–207.
  • DickinsonRB, TranquilloRT. 1993. Optimal estimation of cell movement indices from the statistical analysis of cell tracking data. Am Inst Chem Eng J. 39:1995–2010.
  • EastwoodM, PorterR, KhanU, McGroutherG, BrownR. 1996. Quantitative analysis of collagen gel contractile forces generated by dermal fibroblasts and the relationship to cell morphology. J Cell Physiol. 166:33–42.
  • EhrbarM, SalaA, LienemannP, RangaA, MosiewiczK, BittermannA, RizziSC, WeberFE. 2011. Elucidating the role of matrix stiffness in 3D cell migration and remodeling. Biophys J. 100:284–293.
  • EhrlichHP, RajaratnamJB. 1990. Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction. Tissue Cell. 22:407–417.
  • GranerF, GlazierJ. 1992. Simulations of biological cell sortin using a two-dimensional extended potts model. Phys Rev Lett. 69:2013–2016.
  • HadjipanayiE, MuderaV, BrownRA. 2009. Guiding cell migration in 3D: a collagen matrix with graded directional stiffness. Cell Motil Cytoskeleton. 66:435–445.
  • HarrisAK, WildP, StopakD. 1980. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science. 208:177–179.
  • HibbitHD, KarlsonBI, SorensenP. 2006. ABAQUS Theory Manual, Version 6.10.Pawtucket, Rhode Island, USA.
  • IngberDE, TensegrityI. 2003. Cell structure and hierarchical systems biology. J Cell Sci. 116:1157–1173.
  • JamesDW, TaylorJF. 1969. The stress developed by sheets of chick fibroblasts in vitro. Exp Cell Res. 54:107–110.
  • JulianoRL, HaskillS. 1993. Signal transduction from the extracellular matrix. J Cell Biol. 120:577–585.
  • KanekarS, BorgTK, TerracioL, CarverW. 2000. Modulation of heart fibroblast migration and collagen gel contraction by IGF-I. Cell Adhes Commun. 7:513–523.
  • LauffenburgerDA, HorwitzAF. 1996. Cell migration: a physically integrated molecular process. Cell. 84:359–369.
  • LeeJ, IshiharaA, OxfordG, JohnsonB, JacobsonK. 1999. Regulation of cell movement is mediated by stretch-activated calcium channels. Nature. 400:382–386.
  • LoCM, WangHB, DemboM, WangYL. 2000. Cell movement is guided by the rigidity of the substrate. Biophys J. 79:144–152.
  • LeventalKR, YuH, KassL, LakinsJN, EgebladM, ErlerJT, FongSF, CsiszarK, GiacciaA, WeningerW, YamauchiM, GasserDL, WeaverVM.2009. Matrix cross linking forces tumor progression by enhancing integrin signaling. Cell. 139:891–906.
  • MartinP. 1997. Wound healing: aiming for perfect skin regeneration. Science. 276:75–81.
  • MoreoP, Garcia-AznarJM, DoblaréM. 2008. Modeling mechanosensing and its effect on the migration and proliferation of adherent cells. Acta Biomater. 4:613–621.
  • NossalR. 1988. On the elasticity of cytoskeletal networks. Biophys J. 53:349–359.
  • OdellGM, BonnerJT. 1986. How the dictyostelium discoideum grex crawls. Phil Trans Roy Soc London. 312:487–525.
  • OsterGF, MurrayJD, HarrisAK. 1983. Mechanical aspects of mesenchymal morphogenesis. J Embryol Exp Morph. 78:83–125.
  • PalssonE. 2001. A three-dimensional model of cell movement in multicellular systems. Future Gen Comput Syst. 17:835–852.
  • PelhamRJ, Jr, WangYL. 1997. Cell locomotion and focal adhesions are regulated by substrate flexibility. PNAS. 94:13661–13665.
  • PenelopeCG, JanmeyPA. 2005. Cell type-specific response to growth on soft materials. J Appl Physiol. 98:1547–1553.
  • PompeT, GloriusS, BischoffT, UhlmannI, KaufmannM, BrennerS, WernerC. 2009. Dissecting the impact of matrix anchorage and elasticity in cell adhesion. Biophys J. 97:2154–2163.
  • Ramis-CondeI, DrasdoD, AndersonARA, ChaplainM. 2008. Modeling the influence of the e-cadherin-b-catenin pathway in cancer cell invasion: a multiscale approach. Biophys J. 95:155–165.
  • RamtaniS. 2004. Mechanical modelling of cell/ECM and cell/cell interactions during the contraction of a fibroblast-populated collagen microsphere: theory and model simulation. J Biomech. 37:1709–1718.
  • RassierDE, MacIntoshBR, HerzogW. 1999. Length dependence of active force production in skeletal muscle. J Appl Physiol. 86:1445–1457.
  • RoyP, PetrollWM, CavanaghHD, JesterJV. 1999. Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhesion. Cell Motil Cytoskeleton. 43:23–34.
  • SavillN, HogewegP. 1997. Modeling morphogenesis: from single cells to crawling slugs. J Theor Biol. 184:229–235.
  • SchäferA, RadmacherM. 2005. Influence of myosin ii activity on stiffness of fibroblast cells. Acta Biomater. 1:273–280.
  • SheetzMP, FelsenfeldD, GalbraithCG, ChoquetD. 1997. Cell migration as a five-step cycle. Biochem Soc Symp. 65:233–243.
  • ShiuYT, LiS, MarganskiW, UamiS, SchwartzMA, WangYL, DemboM, ChienS. 2004. Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J. 86:2558–2565.
  • ShreiberDI, BarocasVH, TranquilloRT. 2003. Temporal variations in cell migration and traction during fibroblast-mediated gel compaction. Biophys J. 84:4102–4114.
  • SpudichJA. 2001. The myosin swinging cross-bridge model. Nat Rev Mol Cell Biol. 2:387–392.
  • SureshS. 2007. Biomechanics and biophysics of cancer cells. Acta Biomater. 3:413–438.
  • TaylorDL, HeipleJ, WangYL, LunaEJ, TanasugarnL, BrierJ, SwansonJ, FechheimerM, AmatoP, RockwellM, DaleyG. 1982. Cellular and molecular aspects of amoeboid movement. CSH Symp Quant Biol. 46:101–111.
  • TimoshenkoS, GoodierJN. 1970. Theory of elasticity. New York: McGraw-Hill Publishing Co.
  • UlrichTA, PardoEMDJ, KumarS. 2009. The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res. 69:4167–4174.
  • ZamanMH, KammRD, MatsudairaP, LauffenburgeryDA. 2005. Computational model for cell migration in three-dimensional matrices. Biophys J. 89:1389–1397.

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