A mechanobiological model of endothelial cell migration and proliferation

References

• Bailon-PlazaA, van der MeulenMC. 2001. A mathematical framework to study the effects of growth factor influences on fracture healing. J Theor Biol. 212(2):191–209.
   PubMed Web of Science ®Google Scholar
• BurkeD, DishowitzM, SweetwyneM, MiedelE, HankensonKD, KellyDJ. 2013. The role of oxygen as a regulator of stem cell fate during fracture repair in TSP2-null mice. J Orthop Res.31(10):1585–1596.
   PubMed Web of Science ®Google Scholar
• BurkeD, KellyDJ. 2012. Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: a mechanobiological model. PLoS One. 7(7):e40737.
   PubMed Web of Science ®Google Scholar
• ByrneDP, LacroixD, PlanellJA, KellyDJ, PrendergastPJ. 2007. Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: application of mechanobiological models in tissue engineering. Biomaterials. 28(36):5544–5554.
   PubMed Web of Science ®Google Scholar
• CenniE. 2005. Angiogenesis and bone regeneration. J Bone Joint Surg Br. 87-B(Suppl. I):58.
   Google Scholar
• ChecaS, ByrneDP, PrendergastPJ. 2012. Predictive modelling in mechanobiology: combining algorithms for cell activities in response to physical stimuli using a lattice-modelling approach. Adv Struct Mater. 1(1):423–435.
   Google Scholar
• ChecaS, PrendergastPJ. 2009. A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach. Ann Biomed Eng. 37(1):129–145.
   PubMed Web of Science ®Google Scholar
• ChecaS, PrendergastPJ. 2010. Effect of cell seeding and mechanical loading on vascularization and tissue formation inside a scaffold: a mechano-biological model using a lattice approach to simulate cell activity. J Biomech. 43(5):961–968.
   PubMed Web of Science ®Google Scholar
• FehrerC, BrunauerR, LaschoberG, UnterluggauerH, ReitingerS, KlossF, GullyC, GassnerR, LepperdingerG. 2007. Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan. Aging Cell. 6(6):745–757.
   PubMed Web of Science ®Google Scholar
• GerhardtH, GoldingM, FruttigerM, RuhrbergC, LundkvistA, AbramssonA, JeltschM, MitchellC, AlitaloK, ShimaD, et al. 2003. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 161(6):1163–1177.
   PubMed Web of Science ®Google Scholar
• GerisL, SlotenJV, Van OosterwyckH. 2010. Connecting biology and mechanics in fracture healing: an integrated mathematical modeling framework for the study of nonunions. Biomech Model Mechanobiol. 9(6):713–724.
   PubMed Web of Science ®Google Scholar
• GerisL, VandammeK, NaertI, Vander SlotenJ, Van OosterwyckH, DuyckJ. 2010. Mechanical loading affects angiogenesis and osteogenesis in an in vivo bone chamber: a modeling study. Tissue Eng A. 16(11):3353–3361.
   PubMed Web of Science ®Google Scholar
• GuoS, DipietroLA. 2010. Factors affecting wound healing. J Dent Res. 89(3):219–229.
   PubMed Web of Science ®Google Scholar
• HeppenstallRB, GrislisG, HuntTK. 1975. Tissue gas tensions and oxygen consumption in healing bone defects. Clin Orthop Relat Res. 106:357–365.
   PubMed Web of Science ®Google Scholar
• HiraoM, TamaiN, TsumakiN, YoshikawaH, MyouiA. 2006. Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification. J Biol Chem. 281(41):31079–31092.
   PubMed Web of Science ®Google Scholar
• HolzwarthC, VaeglerM, GiesekeF, PfisterSM, HandgretingerR, KerstG, MullerI. 2010. Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells. BMC Cell Biol. 11:11. https://doi.org/doi:10.1186/1471-2121-11-11.
   PubMed Web of Science ®Google Scholar
• JoungIS, IwamotoMN, ShiuYT, QuamCT. 2006. Cyclic strain modulates tubulogenesis of endothelial cells in a 3D tissue culture model. Microvasc Res. 71(1):1–11.
   PubMed Web of Science ®Google Scholar
• KanichaiM, FergusonD, PrendergastPJ, CampbellVA. 2008. Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha. J Cell Physiol. 216(3):708–715.
   PubMed Web of Science ®Google Scholar
• KhayyeriH, ChecaS, TagilM, PrendergastPJ. 2009. Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach. J Orthop Res. 27(12):1659–1666.
   PubMed Web of Science ®Google Scholar
• KilarskiWW, SamolovB, PeterssonL, KvantaA, GerwinsP. 2009. Biomechanical regulation of blood vessel growth during tissue vascularization. Nat Med. 15(6):657–664.
   PubMed Web of Science ®Google Scholar
• KrishnanL, UnderwoodCJ, MaasS, EllisBJ, KodeTC, HoyingJB, WeissJA. 2008. Effect of mechanical boundary conditions on orientation of angiogenic microvessels. Cardiovasc Res. 78(2):324–332.
   PubMed Web of Science ®Google Scholar
• LacroixD, PrendergastPJ. 2002. A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading. J Biomech. 35(9):1163–1171.
   PubMed Web of Science ®Google Scholar
• LuC, MiclauT, HuD, MarcucioRS. 2007. Ischemia leads to delayed union during fracture healing: a mouse model. J Orthop Res. 25(1):51–61.
   PubMed Web of Science ®Google Scholar
• MatsubaraH, HoganDE, MorganEF, MortlockDP, EinhornTA, GerstenfeldLC. 2012. Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis. Bone. 51(1):168–180.
   PubMed Web of Science ®Google Scholar
• MatsumotoT, YungYC, FischbachC, KongHJ, NakaokaR, MooneyDJ. 2007. Mechanical strain regulates endothelial cell patterning in vitro. Tissue Eng. 13(1):207–217.
   PubMedGoogle Scholar
• MeyerEG, BuckleyCT, ThorpeSD, KellyDJ. 2010. Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression. J Biomech. 43(13):2516–2523.
   PubMed Web of Science ®Google Scholar
• MorettiM, Prina-MelloA, ReidAJ, BarronV, PrendergastPJ. 2004. Endothelial cell alignment on cyclically-stretched silicone surfaces. J Mater Sci Mater Med. 15(10):1159–1164.
   PubMed Web of Science ®Google Scholar
• NomiM, AtalaA, CoppiPD, SokerS. 2002. Principals of neovascularization for tissue engineering. Mol Aspects Med. 23(6):463–483.
   PubMedGoogle Scholar
• PeifferV, GerischA, VandepitteD, Van OosterwyckH, GerisL. 2011. A hybrid bioregulatory model of angiogenesis during bone fracture healing. Biomech Model Mechanobiol. 10(3):383–395.
   PubMed Web of Science ®Google Scholar
• PerezMA, PrendergastPJ. 2007. Random-walk models of cell dispersal included in mechanobiological simulations of tissue differentiation. J Biomech. 40(10):2244–2253.
   PubMed Web of Science ®Google Scholar
• SandinoC, ChecaS, PrendergastPJ, LacroixD. 2010. Simulation of angiogenesis and cell differentiation in a CaP scaffold subjected to compressive strains using a lattice modeling approach. Biomaterials. 31(8):2446–2452.
   PubMed Web of Science ®Google Scholar
• SheehyEJ, BuckleyCT, KellyDJ. 2012. Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells. Biochem Biophys Res Commun. 417(1):305–310.
   PubMed Web of Science ®Google Scholar
• ShweikiD, ItinA, SofferD, KeshetE. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359(6398):843–845.
   PubMed Web of Science ®Google Scholar
• StreetJ, BaoM, deGuzmanL, BuntingS, Peale, Jr, FV, FerraraN, SteinmetzH, HoeffelJ, ClelandJL, DaughertyA, et al. 2002. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA. 99(15):9656–9661.
   PubMed Web of Science ®Google Scholar
• van der MeulenMC, HuiskesR. 2002. Why mechanobiology? A survey article. J Biomech. 35(4):401–414.
   PubMed Web of Science ®Google Scholar
• Von Offenberg SweeneyN, CumminsPM, CotterEJ, FitzpatrickPA, BirneyYA, RedmondEM, CahillPA. 2005. Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation. Biochem Biophys Res Commun. 329(2):573–582.
   PubMed Web of Science ®Google Scholar
• YanZQ, LiYQ, ChengBB, YaoQP, GaoLZ, GaoQC, GongXB, QiYX, JiangZL. 2013. Effects of stretched vascular endothelial cells and smooth muscle cells on differentiation of endothelial progenitor cellss. J Mech Med. 13(2):1350050.
   Web of Science ®Google Scholar
• YungYC, ChaeJ, BuehlerMJ, HunterCP, MooneyDJ. 2009. Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci USA. 106(36):15279–15284.
   PubMed Web of Science ®Google Scholar