183
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Dietary fibre-rich resistant starches promote ammonia detoxification in the human colon as measured by lactose-[15N2]ureide

, , &
Pages 488-496 | Received 19 May 2015, Accepted 16 Aug 2015, Published online: 24 Oct 2015

References

  • Wutzke KD, Oetjens I. 13C- and 15N-incorporation of doubly stable isotope labelled Lactobacillus johnsonii in humans. Eur J Clin Nutr. 2005;59:1167–1172. doi: 10.1038/sj.ejcn.1602227
  • Dhingra D, Michael M, Rajput H, Patil RT. Dietary fibre in foods: a review. J Food Sci Technol. 2012;49:255–266. doi: 10.1007/s13197-011-0365-5
  • Cloetens L, De Preter V, De Loor H, Rutgeerts P, Verbeke K. Does the biomarker 15N-lactose ureide allow to estimate the site of fermentation of resistant starch? Eur J Nutr. 2008;47:217–223. doi: 10.1007/s00394-008-0716-9
  • Wutzke KD, Lotz M, Zipprich C. The effect of pre- and probiotics on the colonic ammonia metabolism in humans as measured by lactose-[15N2]ureide. Eur J Clin Nutr. 2010;64:1215–1221. doi: 10.1038/ejcn.2010.120
  • Smith EA, Macfarlane GT. Enumeration of human colonic bacteria producing phenolic and indolic compounds: effects of pH, carbohydrate availability and retention time on dissimilatory aromatic amino acid metabolism. J Appl Bacteriol. 1996;81:288–302. doi: 10.1111/j.1365-2672.1996.tb04331.x
  • Macfarlane GT, Cummings JH. The colonic flora, fermentation and large bowel digestive function. In: Phillips SF, Pemberton H, Shorter RG, editors. The large intestine: physiology, pathophysiology and disease. New York, NY: Raven; 1991. p. 51–92.
  • De Preter V, Verbeke K. Evaluation of the necessity of induction for lactose-[15N,15N]-ureide to study the colonic ammonia metabolism. Scand J Gastroenterol. 2006;41:396–400. doi: 10.1080/00365520500279688
  • De Preter V, Vanhoutte T, Huys G, Swings J, Rutgeerts P, Verbeke K. Baseline microbiota activity and initial bifidobacteria counts influence responses to prebiotic dosing in healthy subjects. Aliment Pharmacol Ther. 2008;27:504–513. doi: 10.1111/j.1365-2036.2007.03588.x
  • Cummings JH, Macfarlane GT. Gastrointestinal effects of prebiotics. Br J Nutr. 2002;87(Suppl 2):145–151. doi: 10.1079/BJN/2002530
  • Heine WE, Berthold HK, Klein PD. A novel stable isotope breath test: 13C-labeled glycosylureides used as noninvasive markers of intestinal transit time. Am J Gastroenterol. 1995;90:93–98.
  • Wutzke KD, Heine WE, Plath C, et al. Evaluation of oro-coecal transit time: a comparison of the lactose-[13C, 15N]ureide 13CO2- and the lactulose H2-breath test. Eur J Clin Nutr. 1997;51:11–19. doi: 10.1038/sj.ejcn.1600353
  • Geypens B, Bennink R, Peeters M, et al. Validation of the lactose-[13C]ureide breath test for determination of orocecal transit time by scintigraphy. J Nucl Med. 1999;40:1451–1455.
  • Van den Driessche M, Van Malderen N, Geypens B, et al. Lactose-[13C]ureide breath test: a new, noninvasive technique to determine orocecal transit time in children. J Pediatr Gastroenterol Nutr. 2000;31:433–488. doi: 10.1097/00005176-200010000-00019
  • Morrison DJ, Dodson B, Preston T, Weaver LT. Gastrointestinal handling of glycosyl [13C]ureides. Eur J Clin Nutr. 2003;57:1017–1024. doi: 10.1038/sj.ejcn.1601637
  • Wutzke KD, Glasenapp B. The use of 13C-labelled glycosyl ureides for evaluation of orocaecal transit time. Eur J Clin Nutr. 2004;58:568–572. doi: 10.1038/sj.ejcn.1601846
  • Wutzke KD, Schütt M. The duration of enzyme induction in oroceacal transit time measuremenrts. Eur J Clin Nutr. 2007;61:1161–1166. doi: 10.1038/sj.ejcn.1602633
  • Jackson AA, Gibson NR, Bundy R, Hounslow A, Millward DJ, Wootton SA. Transfer of 15N from oral lactose-ureide to lysine in normal adults. Int J Food Sci Nutr. 2004;55:455–462. doi: 10.1080/09637480400015885
  • Geboes KP, De Preter V, Luypaerts A, et al. Validation of lactose [15N,15N]ureide as a tool to study colonic nitrogen metabolism. Am J Physiol Gastrointest Liver Physiol. 2005;288:G994–999. doi: 10.1152/ajpgi.00408.2004
  • Wutzke KD, Scholübbers D. The metabolic effect of resistant starch and yoghurt on the renal and faecal nitrogen and ammonia excretion in humans as measured by lactose-[15N2]ureide. Isot Environ Health Stud. 2013;49:464–470. doi: 10.1080/10256016.2013.804519
  • Mohr C, Heine WE, Wutzke KD. Clostridium innocuum: a glucose ureide splitting inhabitant of the human microbial flora. Biochim Biophys Acta. 1999;1472:550–554. doi: 10.1016/S0304-4165(99)00162-2
  • Faust H, Bornhak H, Hirschberg K, Jung K, Junghans P, Krumbiegel P, Reinhardt R. Klinisch-chemische und isotopenanalytische Methoden zur Untersuchung des Stickstoff-Stoffwechsels mit N-15 beim Menschen. In: Wetzel K, editor. Methodenkatalog. ZfI-Mitteilungen. Vol. 36. Leipzig: Akademie der Wissenschaften; 1981. p. 115–132.
  • Sajilata MG, Singhal RS, Kulkarni PR. Resistant starch – a review. Compr Rev Food Sci Food Saf. 2006;5:1–17. doi: 10.1111/j.1541-4337.2006.tb00076.x
  • De Preter V, Houben E, Windey K, Luypaerts A, Verbeke K. Analysis of the urinary glucose-[15N,15N]-ureide content in the study of the lactose-[15N,15N]-ureide metabolism in healthy humans. Eur J Clin Nutr. 2011;65:959–964. doi: 10.1038/ejcn.2011.63
  • Wutzke KD, Mix J. The metabolic fate of doubly labelled lactose-[13C,15N]ureide after pre-dosing with different ureides. Eur J Clin Nutr. 2010;64:733–738. doi: 10.1038/ejcn.2010.84
  • De Preter V, Vanhoutte T, Huys G, Swings J, Rutgeerts P, Verbeke K. Effect of lactulose and Saccharomyces boulardii administration on the colonic urea-nitrogen metabolism and the bifidobacteria concentration in healthy human subjects. Aliment Pharmacol Ther. 2006;23:963–974. doi: 10.1111/j.1365-2036.2006.02834.x
  • Heijnen ML, Beynen AC. Consumption of retrograded (RS3) but not uncooked (RS2) resistant starch shifts nitrogen excretion from urine to feces in cannulated piglets. J Nutr. 1997;127:1828–1832.
  • Birkett A, Muir J, Phillips J, Jones G, O'Dea K. Resistant starch lowers fecal concentrations of ammonia and phenols in humans. Am J Clin Nutr. 1996;63:766–772.
  • Higgins JA, Higbee DR, Donahoo WT, Brown IL, Bell ML, Bessesen DH. Resistant starch consumption promotes lipid oxidation. Nutr Metab (Lond). 2004;1:8. doi: 10.1186/1743-7075-1-8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.