Amplified Molecular Binding of Prion Protein Homologues in Self-progressive Injury of Neuronal Membranes and Trafficking Systems

References

• Andreolletti , O. , Levavasseur , E. , Uro-Coste , E. , Tabouret , G. , Sarradin , P. , Delisle , M.B. , Berthon , P. , Salvayre , R. , Schelcher , F. and Negre-Salvayre , A. 2002 . Astrocytes accumulate 4-hydroxynonenal adducts in murine scrapie and human Creutzfeldt-Jakob disease . Neurobiol. Dis. , 11 ( 3 ) : 386 – 393 .
   Google Scholar
• Aucouturier , P. and Carnaud , C. 2002 . The immune system and prion diseases: a relationship of complicity and blindness . J. Leukoc. Biol. , 72 ( 6 ) : 1075 – 1083 .
   Web of Science ®Google Scholar
• Behrems , A. and Aguzzi , A. 2002 . Small is not beautiful: antagonizing functions for the prion protein PrP and its homologue Dpl . Trends Neurosci. , 25 ( 3 ) : 160 – 164 .
   Google Scholar
• Behrems , A. , Brandner , S. , Genoud , N. and Aguzzi , A. 2001 . Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel . EMBO Rep. , 2 ( 4 ) : 347 – 352 .
   Google Scholar
• Butowt , R. and Von Bartheld , C.S. 2003 . Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR . Eur. J. Neurosci. , 17 ( 4 ) : 673 – 680 .
   Google Scholar
• Combrink , M.I. , Perry , V.H. and Cunningham , C. 2002 . Peripheral infection evokes exaggerated sickness behavior in pre-clinical murine prion disease . Neuroscience , 112 ( 1 ) : 7 – 11 .
   Google Scholar
• Drisko , J.A. 2002 . The use of antioxidants in transmissible spongiform encephalopathies: a case report . J. Am. Coll. Nutrit. , 21 ( 1 ) : 22 – 25 .
   PubMed Web of Science ®Google Scholar
• Eikelembroom , P. , Bate , C. , Van Gool , W.A. , Hoozemans , J.J. , Rozemuller , J.M. , Veerhuis , R. and Williams , A. 2002 . Neuroinflammation in Alzheimer's disease and prion disease . Glia , 40 ( 2 ) : 232 – 239 .
   Google Scholar
• Fraser , J.R. 2002 . What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired? . Neuropathol. Appl. Neurobiol. , 28 ( 1 ) : 1 – 11 .
   Google Scholar
• Gibson , T.J. 2001 . RuNAway disease: a two cycle model for transmissible spongiform encephalopathies (TSEs) wherein SINE proliferation drives PrP overproduction . Genome Biol. , 2 ( 7 ) Preprint 0006
   Google Scholar
• Grossman , A. , Zeiler , B. and Sapirstein , V. 2003 . Prion protein interactions with nucleic acid: possible models for prion disease and prion function . Neurochem. Res. , 28 ( 6 ) : 955 – 963 .
   Google Scholar
• Guentchev , M. , Voigtlander , T. , Haberler , C. , Groxhup , M.H. and Budka , H. 2000 . Evidence for oxidative stress in experimental prion disease . Neurobiol. Dis. , 7 ( 4 ) : 270 – 273 .
   PubMed Web of Science ®Google Scholar
• Irani , D.M. 2003 . The classic and variant forms of Creutzfeldt-Jakob disease . Semin. Clin. Neuropsychiatry , 8 ( 1 ) : 71 – 79 .
   Google Scholar
• Jesionek-Kupnicka , D. , Kordk , R. , Buczynski , J. and Liberski , P.P. 2001 . Apoptosis in relation to neuronal loss in experimental Creutzfeldt-Jakob disease in mice . Acta Neurobiol. Exp. (Warsz) , 61 ( 1 ) : 13 – 19 .
   Web of Science ®Google Scholar
• Johnston , A.R. , Fraser , J.R. , Jeffrey , M. and MacLeod , N. 1998 . Synaptic plasticity in the CA1 area of the hippocampus of scrapie-infected mice . Neurobiol. Dis. , 5 ( 3 ) : 188 – 195 .
   PubMed Web of Science ®Google Scholar
• Kretzschmar , H.A. 1999 . Molecular pathogenesis of prion diseases . Eur. Arch. Psychiatry Clin. Neurosci. , 249 ( Suppl. 3 ) : 56 – 63 .
   Google Scholar
• Kunzi , V. , Glatzel , M. , Nakano , M.Y. , Greher , U.F. , Van Leuven , F. and Aguzzi , A. 2002 . Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau . J. Neurosci. , 22 ( 17 ) : 7471 – 7477 .
   Google Scholar
• Offeu , D. , Elkon , H. and Melamed , E. 2000 . Apoptosis as a general cell death pathway in neurodegenerative diseases . J. Neural. Transm. Suppl. , : 153 – 166 .
   Google Scholar
• OMIM 176640 Prion Protein; PRNP.
   Google Scholar
• OMIM 123400 Creutzfeldt Jakob Disease; CJD.
   Google Scholar
• Rybner , C. , Hillion , J. , Sahravui , T. , Lanotte , M. and Botti , J. 2002 . All-trans retinoic acid downregulates prion protein expression independently of granulocyte maturation . Leukemia , 16 ( 5 ) : 940 – 948 .
   Google Scholar
• Ryon , C. , Prusiner , S.B. and Legname , G. 2003 . Cooperative binding of dominant-negative prion protein to kringle domains . J. Mol. Biol. , 329 ( 2 ) : 323 – 333 .
   Google Scholar
• Sasaki , K. , Doh-ura , K. , Ironside , J.W. and Iwaki , T. 2002 . Increased clusterin (apolipoprotein J) expression in human and mouse brains infected with transmissible spongiform encephalopathies . Acta Neuropathol. (Berl.) , 103 ( 3 ) : 199 – 208 .
   Google Scholar
• Schroder , B. , Nickodemus , R. , Jurgens , T. and Bodemer , W. 2002 . Upstream AUGs modulate prion protein translation in vitro . Acta Virol. , 46 ( 3 ) : 159 – 167 .
   Google Scholar
• Stumpf , M.P. and Krakauer , D.C. 2000 . Mapping the parameters of prion-induced neuropathology . Proc. Natl Acad. Sci. USA , 97 ( 19 ) : 10573 – 10577 .
   Google Scholar
• Thellung , S. , Florio , T. , Villa , V. , Corsaro , A. , Arena , S. , Amico , C. , Robello , M. , Salmona , M. , Forloni , G. Bugiani . 2000 . Apoptotic cell death—impairment of L-Type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106–126 . Neurobiol. Dis. , 7 ( 4 ) : 299 – 309 .
   Google Scholar
• Trojanowski , J.Q. and Lee , V.M. 2003 . Fatal attractions of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders . Ann. NY Acad. Sci. , 924 : 62 – 67 .
   Google Scholar
• White , A.R. , Huang , X. , Jobling , M.F. , Barrow , C.J. , Beyreuther , K. , Masters , C.L. , Bush , A.I. and Ceppai , R. 2001 . Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's type neurodegenerative pathways . J. Neurochem. , 76 ( 5 ) : 1509 – 1520 .
   Google Scholar
• Wong , B.S. , Green , A.J. , Li , R. , Xie , Z. , Pan , T. , Liu , T. , Chen , S.G. , Gambetti , P. and Sy , M.-S . 2001 . Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease . J. Pathol. , 194 ( 1 ) : 9 – 14 .
   PubMed Web of Science ®Google Scholar
• Yanagihara , C. , Yasuda , M. , Maeda , K. , Miyoshi , K. and Nishimura , Y. 2002 . Rapidly progressive dementia syndrome associated with a novel four extra repeat mutation in the prion protein gene . J. Neurol. Neurosurg. Psychiatry , 72 ( 6 ) : 788 – 791 .
   Google Scholar
• Zanusso , G. , Vattemi , G. , Ferrari , S. , Tabaton , M. , Pecini , E. , Cavallaro , T. , Tomelleri , G. , Filosto , M. , Tonin , P. , Nardelli , E. , Rizzuto , N. and Monaco , S. 2001 . Increased expression of the normal cellular isoform of prion protein in inclusion-body myositis inflammatory myopathies and denervation atrophy . Brain Pathol. , 11 ( 2 ) : 182 – 189 .
   Google Scholar