Blueberry Supplemented Diet: Effects on Object Recognition Memory and Nuclear Factor-kappa B Levels in Aged Rats

References

• Alessio, H.M., Goldfarb, A.H. and Cao, G. (1997 ) “Exercise-induced oxidative stress before and after vitamin C supplementation”, International Journal of Sport Nutrition 7, 1–9.
   PubMed Web of Science ®Google Scholar
• Baeuerle, P.A. and Baltimore, D. (1996 ) “NF-kB: ten years after”, Cell 87, 13–20.
   PubMed Web of Science ®Google Scholar
• Bartolini, L., Casamenti, F. and Pepeu, G. (1996 ) “Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions”, Pharmacological Biochemical Behavior 53, 277–283.
   PubMed Web of Science ®Google Scholar
• Bickford, P.C., Gould, T., Briederick, L., Chadman, K., Pollock, A., Young, D., Shukitt-Hale, B. and Joseph, J. (2000 ) “Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats”, Brain Research 866, 211–217.
   PubMed Web of Science ®Google Scholar
• Cao, G., Verdon, C.P., We, A., Wang, H. and Prior, R.L. (1995 ) “Automated oxygen radical absorbance capacity assay using the COBAS FARA II”, Clinical Chemistry 41, 1738–1744.
   PubMed Web of Science ®Google Scholar
• Cartford, M.C., Casadesus, G. and Bickford, P.C. (2002 ) “Eighteen-month-old Fischer-344 rats fed a spinach-enriched diet show improved delay classical eyeblink conditioning and reduced expression of tumor necrosis factor alpha (TNFalpha) and TNFbeta in the cerebellum”, Journal Neuroscience 22, 5813–5816.
   PubMed Web of Science ®Google Scholar
• Casadesus, G., Mesches, M.H., Sepesi, B., Choo, K., Holmes, D.B. and Bickford, P.C. (2002 ) “Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines”, Journal of Neuroscience 22, 6114–6120.
   PubMed Web of Science ®Google Scholar
• Chen, P., Ratcliff, G., Belle, S.H., Cauley, J.A., DeKosky, S.T. and Ganguli, M. (2001 ) “Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study”, Archives of General Psychiatry 58, 859–860.
   PubMedGoogle Scholar
• Chevion, M., Berenstein, E. and Stadtman, E.R. (2000) “Human studies related to protein oxidation: protein carbonyl content as a marker of damage”, Free Radical Research Supplement S, 99–108.
   Google Scholar
• Chung, M.H., Kasai, H., Nishimura, S. and Yu, B.P. (1992 ) “Protection of DNA damage by dietary restriction”, Free Radical Biological Medicine 12, 523–525.
   PubMed Web of Science ®Google Scholar
• Clark, R.E., Zola, S.M. and Squire, L.R. (2000 ) “Impaired recognition memory in rats after damage to the hippocampus”, Journal of Neuroscience 20, 8853–8860.
   PubMed Web of Science ®Google Scholar
• Daniels, W.M., van Rensburg, S.J., van Zyl, J.M. and Taljaard, J.J. (1998 ) “Melatonin prevents beta-amyloid—induced lipid peroxidation”, Journal of Pineal Research 24, 78–82.
   PubMed Web of Science ®Google Scholar
• Dellu, F., Mayo, W., Cherkaoui, J., Le Moal, M. and Simon, H. (1992 ) “A two-trial memory task with automated recording: study in young and aged rats”, Brain Research 588, 132–139.
   PubMed Web of Science ®Google Scholar
• Ennaceur, A. and Delacour, J. (1988 ) “A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data”, Behavioral Brain Research 31, 47–59.
   PubMed Web of Science ®Google Scholar
• Fleischman, D.A., Gabrieli, J.D., Reminger, S., Rinaldi, J., Morrell, F. and Wilson, R. (1995 ) “Conceptual priming in perceptual identification for patients with Alzheimer’s disease and a patient with right occipital lobectomy”, Neuropsychology 9, 187–197.
   Web of Science ®Google Scholar
• Flohe, L., Brigelius-Flohe, R., Saliou, C., Traber, M.G. and Packer, L. (1997 ) “Redox regulation of NF-kappa B activation”, Free Radicals Biological Medicine 22, 115–1126.
   Google Scholar
• Galli, R.L., Shukitt-Hale, B., Youdim, K.A. and Joseph, J.A. (2002 ) “Fruit polyphenolics and brain aging”, Annals of the New York Academy of Sciences 959, 128–132.
   PubMed Web of Science ®Google Scholar
• Gill, N. and Josman, N. (2001 ) “Memory and metamemory performance in Alzheimer’s disease and healthy elderly: the Contextual Memory Test (CMT)”, Aging 13, 309–315.
   PubMedGoogle Scholar
• Harman, D. (1956 ) “Aging: a theory based on free radical and radiation chemistry”, Journal of Gerontologist 11, 298.
   PubMedGoogle Scholar
• Heilbronn, L.L. and Ravussin, E. (2003 ) “Calorie restriction and aging: review of the literature and implications for studies in humans”, American Journal of Clinical Nutrition 78, 361–69.
   PubMed Web of Science ®Google Scholar
• Joseph, D.A., Denisova, N.A., Villalobos-Molina, R., Erat, S. and Strain, J. (1996 ) “Oxidative stress and age-related neuronal deficits”, Molecular and Chemical Neuropathology 28, 35–40.
   PubMedGoogle Scholar
• Joseph, J.A., Denisova, N.A., Fisher, D., Bickford, P., Prior, R. and Cao, G. (1998a ) “Age-related neurodegeneration and oxidative stress. Putative Nutritional Intervention”, Neurologic Clinics of North America 16, 747–752.
   PubMed Web of Science ®Google Scholar
• Joseph, J.A., Denisova, N.A., Fisher, D., Bickford, P., Prior, R. and Cao, G. (1998b ) “Membrane and receptor modifications of oxidative stress vulnerability in aging. Nutritional considerations”, Annals of the New York Academy of Sciences 854, 268–276.
   PubMed Web of Science ®Google Scholar
• Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Prior, R., Cao, G., Martin, A., Taglialatela, G. and Bickford, P.C. (1998c ) “Longterm dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal transduction and cognitive behavioral deficits”, The Journal of Neuroscience 18, 8047–8055.
   PubMed Web of Science ®Google Scholar
• Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J. and Bickford, P.C. (1999 ) “Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation”, The Journal of Neuroscience 19, 8114–8121.
   PubMed Web of Science ®Google Scholar
• Joyce, C.A., Paller, K.A., McIsaac, H.K. and Kutas, M. (1998 ) “Memory changes with normal aging: behavioral and electrophysiological measures”, Psychophysiology 35, 669–678.
   PubMed Web of Science ®Google Scholar
• Kaufmann, J.A., Bickford, P.C. and Taglialatela, G. (2002 ) “Free radical-dependent changes in constitutive nuclear factor kappa B in the aged hippocampus”, Neuroreport 13, 1917–1920.
   PubMed Web of Science ®Google Scholar
• Korhonen, P., Helenius, M. and Salminen, A. (1997 ) “Age-related changes in the regulation of transcription factor NF-kappa B in rat brain”, Neuroscience Letter 225, 61–64.
   PubMed Web of Science ®Google Scholar
• Lee, A.C., Rahman, S., Hodge, J.R., Sahakian, B.J. and Graham, K.S. (2003 ) “Associative and recognitions memory for novel objects in dementia: implications for diagnosis”, European Journal of Neuroscience 18, 1660–1670.
   PubMed Web of Science ®Google Scholar
• Leiner, H.C., Leiner, A.L. and Dow, R.S. (1993 ) “Cognitive and language functions of the human cerebellum”, Trends in Neuroscience 16, 444–447.
   PubMed Web of Science ®Google Scholar
• Lekeu, F., Van der Linden, M., Degueldre, D., Lemaire, C., Luxen, A., Franck, G., Moonen, G. and Salmon, E. (2003 ) “Effects of Alzheimer’s disease on the recognition of novel versus familiar works: neuropsychological and clinico-metabolic data”, Neuropsychology 17, 143–154.
   PubMed Web of Science ®Google Scholar
• Li, N. and Karin, M. (1999 ) “Is NFkB the sensor of oxidative stress?”, The FASEB Journal 13, 137–143.
   Google Scholar
• Li, X. and Stark, G.R. (2002 ) “NFkB-dependent signaling pathways”, Experimental Hematology 30, 285–296.
   PubMed Web of Science ®Google Scholar
• Mattson, M.P. and Simonetta, C. (2001 ) “NFkB in neuronal plasticity and neurodegenerative disorders”, The Journal of Clinical Investigation 107, 247–254.
   PubMed Web of Science ®Google Scholar
• Mattson, M.P., Culmsee, C., Yu, Z. and Camandola, S. (2000 ) “Roles of nuclear factor kappaB in neuronal survival and plasticity”, Journal of Neurochemistry 74, 443–456.
   PubMed Web of Science ®Google Scholar
• Minamoto, H., Tachibana, H., Sugita, M. and Okita, T. (2001 ) “Recognition memory in normal aging and Parkinson’s disease: behavioral and electrophysiologic measures”, Cognitive Brain Research 11, 23–32.
   PubMedGoogle Scholar
• Mizuno, Y. and Ohta, K. (1986 ) “Regional distributions of thiobarbituric acid-reactive products, activities of enzymes regulating the metabolism of oxygen free radicals, and some of the related enzymes in adult and aged rat brains”, Journal of Neurochemistry 46, 1344–1352.
   PubMed Web of Science ®Google Scholar
• Moss, M.B., Killiany, R.J., Li, Z.C., Rosene, D.L. and Herndon, J.G. (1997 ) “Recognition memory span in rhesus monkeys of advanced age”, Neurobiology of Aging 18, 13–19.
   PubMed Web of Science ®Google Scholar
• Olanow, C.W. (1992 ) “An introduction to the free radical hypothesis in Parkinson’s disease”, Annals of Neurology 32, S2–S9.
   PubMed Web of Science ®Google Scholar
• Paolisso, G., Tagliamonte, M.R., Rizzo, M.P., Manzella, D., Gambardella, A. and Varricchio, M. (1998 ) “Oxidative stress and advance-ing age: results in healthy centenarians”, Journal ofAmerican Geriatric Society 46, 833–838.
   PubMed Web of Science ®Google Scholar
• Pilotti, M., Meade, M.L. and Gallo, D.A. (2003 ) “Implicit and explicit measures of memory for perceptual information in young adults, healthy older adults, and patients with Alzheimer’s disease”, Experimental Aging Research 29, 15–32.
   PubMed Web of Science ®Google Scholar
• Prior, R.L. and Cao, G. (2000 ) “Analysis of botanicals and dietary supplements for antioxidant capacity: a review”, Journal of AOAC International 83, 950–956.
   PubMed Web of Science ®Google Scholar
• Prior, R.L., Cao, G., Martin, A., Sofic, E., McEwen, J., O’Brien, C., Listener, N., Ehlenfeldt, M., Kalt, W., Krewer, G. and Mainland, M. (1998 ) “Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity and variety of Vaccinium species”, Journal ofAgricultural Food Chemistry 46, 2586–2593.
   Web of Science ®Google Scholar
• Rabbitt, P. and Lowe, C. (2000 ) “Patterns of cognitive ageing”, Psychological Research 63, 308–316.
   PubMed Web of Science ®Google Scholar
• Savory, J., Rao, J.K., Huang, Y., Letada, P.R. and Herman, M.M. (1999 ) “Age-related hippocampal changes in Bcl-2:Bax ratio, oxidative stress, redox-active and apoptosis associated with aluminum-induced neurodegeneration: increased susceptibility with aging”, NeuroToxicology 20, 805–818.
   PubMed Web of Science ®Google Scholar
• Scali, C., Giovannini, M.G., Bartolini, L., Prosperi, C., Hinz, V., Schmidt, B. and Pepeu, G. (1997 ) “Effect of metrifonate on extracellular brain acetylcholine and object recogniton in aged rats”, European Journal of Pharmacology 325, 173–180.
   PubMed Web of Science ®Google Scholar
• Schmahmann, J.D. (1991 ) “An emerging concept. The cerebellar contribution to higher function”, Archives of Neurology 48, 1178–1187.
   PubMed Web of Science ®Google Scholar
• Schreck, R., Albermann, K.J. and Bauerle, P.A. (1992 ) “Nuclear Factor kB: an oxidative stress response transcription factor of eukaryotic cells (a review)”, Free Radical Research Communications 17, 221–237.
   PubMedGoogle Scholar
• Shukitt-Hale, B., Casadeus, G., Cantuti-Castelvetri, I. and Joseph, J.A. (2001 ) “Effect of age on object exploration, habituation, and response to spatial and nonspatial change”, Behavioral Neuroscience 115, 1059–1064.
   PubMed Web of Science ®Google Scholar
• Sizemore, N., Leung, S. and Stark, G.R. (1999 ) “Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kB p65/ Rel A subunit”, Molecular Cell Biology 19, 4798.
   PubMed Web of Science ®Google Scholar
• Socci, D.J., Crandall, B.M. and Arendash, G.W. (1995 ) “Chronic antioxidant treatment improves the cognitive performance of aged rats”, Brain Research 639, 88–94.
   Google Scholar
• Sram, R.J., Binkiova, B., Topinka, J., Kotesovec, F., Fojtikova, I., Hanel, I., Klaschka, J., Kocisova, J., Prosek, M. and Machalek, J. (1993 ) “Effect of antioxidant supplementation in an elderly population ”, In: Bronzetti, G., ed., Antimutagenesis and Anticarcinogenesis Mechanisms III (Plenum Press, New York ), pp 459–477.
   Google Scholar
• Taglialatela, G., Kaufmann, J.A., Trevino, A. and Perez-Polo, J.R. (1998 ) “Central nervous system DNA fragmentation induced by the inhibition of nuclear factor kappa”, Brain Neuroreport 16, 489–493.
   Google Scholar
• Tierney, M.C., Black, S.E., Szalai, J.P., Snow, W.G., Fisher, R.H., Nadon, G. and Chu, H.C. (2001 ) “Recognition memory and verbal fluency differentiate probable Alzheimer disease from subcortical ischemic vascular dementia”, Archives ofNeurology 58, 1654–1659.
   PubMed Web of Science ®Google Scholar
• Toliver-Kinsky, T., Papaconstantinou, J. and Perez-Polo, J.R. (1997 ) “Age-associated alterations in hippocampal and basal forebrain nuclear factor kappa B activity”, Journal of Neuroscience Research 48, 580–587.
   PubMed Web of Science ®Google Scholar
• Toliver-Kinsky, T., Rassin, D. and Perez-Polo, J.R. (2002 ) “NF-kappaB activity decreases in basal forebrain of young and aged rats after hyperoxia”, Neurobiology of Aging 23, 899–905.
   PubMed Web of Science ®Google Scholar
• Tong, L., Toliver-Kinsky, T., Edwards, M., Rassin, D.K., Werrbach-Perez, K. and Perez-Polo, J.R. (2002 ) “Attenuated transcriptional responses to oxidative stress in the aged rat brain”, Journal of Neuroscience Research 70, 318–326.
   PubMed Web of Science ®Google Scholar
• Verhaeghen, P., Vandenbroucke, A. and Dierckx, V. (1998 ) “Growing slower and less accurate: adult age differences in time-accuracy functions for recall and recognition from episodic memory”, Experimental Aging Research 24, 3–19.
   PubMed Web of Science ®Google Scholar
• Youdim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C. and Joseph, J.A. (2000 ) “Short-term dietary supplementation of blueberry polyphenolics: beneficial effects on aging brain performance and peripheral tissue function”, Nutritional Neuroscience 3, 383–397.
   PubMed Web of Science ®Google Scholar
• Youdim, K.A., McDonald, J., Kalt, W. and Joseph, J.A. (2002 ) “Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults (small star, filled)”, Journal of Nutrition Biochemistry 13, 282–288.
   PubMed Web of Science ®Google Scholar
• Yu, B.P., Suescun, E.A. and Yang, A.Y. (1992 ) “Effect of age-related lipid peroxidation on membrane fluidity and phospholipase A2: modulation by dietary restriction”, Mechanisms of Ageing and Development 65, 17–33.
   PubMed Web of Science ®Google Scholar
• Zhang, J.R., Andrus, P.K. and Hall, E.D. (1993 ) “Age-related regional changes in hydroxyl radical stress and antioxidants in gerbil brain”, Journal of Neurochemistry 61, 1640–1647.
   PubMed Web of Science ®Google Scholar