An Association between Low Levels of Dietary Protein, Elevated NPY Gene Expression in the Basomedial Hypothalamus and Increased Food Intake

References

• Beck, B., Dollet, J.-M. and Max, J.-P. (1989) Refeeding after various times of ingestion of a low protein diet: effects on food intake and body weight in rats. Physiology and Behavior 45, 761–765.
   PubMed Web of Science ®Google Scholar
• Black, A., Maddy, K.H. and Swift, R.W. (1950) The influence of low levels of protein on heat production. Journal of Nutrition 42, 415–422.
   PubMed Web of Science ®Google Scholar
• Colombo, J.-P., Cervantes, H., Kokorovic, M., Pfister, U. and Perritaz, R. (1992) Effect of different protein diets on the distribution of amino acids in plasma, liver and brain in the rat. Annals of Nutrition and Metabolism 36, 23–33.
   PubMed Web of Science ®Google Scholar
• Forbes, E.B., Swift, R.W., Marcy, L.F. and Davenport, M.T. (1944) Protein intake and heat production. Journal of Nutrition 28, 189–196.
   Google Scholar
• Frederich, R., Hamann, A., Anderson, S., Lollmann, B., Lowell, B.B. and Flier, J.S. (1995) Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Medicine 1, 1311–1314.
   PubMed Web of Science ®Google Scholar
• Gurr, M.I., Mawson, R., Rothwell, N.J. and Stock, M.J. (1980) Effects of manipulating dietary protein and energy intake on energy balance and thermogenesis in the pig. Journal of Nutrition 110, 532–542.
   PubMed Web of Science ®Google Scholar
• Harris, R.B.S. and Martin, R.J. (1984) Specific depletion of body fat in parabiotic partners of tube-fed obese rats. American Journal of Physiology 247, R380–R386.
   PubMed Web of Science ®Google Scholar
• Hartsook, E.W. and Hershberger, T.V. (1963) A simplified method for sampling small carcasses for analysis. Proceedings of the Society for Experimental Biology and Medicine 113, 973–977.
   PubMed Web of Science ®Google Scholar
• Heard, C.R.C., Frangi, S.M. and Wright, P.M. (1977) Biochemical characteristics of different forms of proteinenergy malnutrition: an experimental model using young rats. British Journal of Nutrition 37, 1–21.
   PubMed Web of Science ®Google Scholar
• Hillgartner, F.B. and Romsos, D.R. (1987) Iodothyronine 5′-deiodination in rats fed low protein diets: lack of correlation with energy balance. Journal of Nutrition 117, 368–375.
   PubMed Web of Science ®Google Scholar
• Kabadi, U.M., Eisenstein, A.B. and Strack, I. (1976) Decreased plasma insulin but normal glucagon in rats fed low-protein diets. Journal of Nutrition 106, 1247–1253.
   PubMed Web of Science ®Google Scholar
• Kyriazakis, I. and Emmans, G.C. (1991) Diet selection in pigs: dietary choices made by growing pigs following a period of underfeeding with protein. Animal Production 52, 337–346.
   Google Scholar
• Le Magnen, J. (1981) The metabolic basis of dual periodicity of feeding in rats. The Behavioral and Brain Sciences 4, 561–607.
   Web of Science ®Google Scholar
• McCracken, K.J. (1976) A futile energy cycle in adult rats given a low-protein diet at high levels of energy intake? Proceedings of the Nutrition Society 35, 59A–60A.
   PubMed Web of Science ®Google Scholar
• Mercer, L.P., Kelly, D.S., Humphries, L.L. and Dunn, J.D. (1994) Manipulation of central nervous system histamine or histaminergic receptors (H1) affects food intake in rats. Journal of Nutrition 124, 1029–1036.
   PubMed Web of Science ®Google Scholar
• Meyer, J.H. (1958) Interaction of dietary fiber and protein on food intake and body composition of growing rats. American Journal of Physiology 193, 488–494.
   PubMed Web of Science ®Google Scholar
• Miller, D.S. and Payne, P.R. (1962) Weight maintenance and food intake. Journal of Nutrition 78, 255–262.
   Web of Science ®Google Scholar
• Noblet, J., Henry, Y. and Dubois, S. (1987) Effect of protein and lysine levels in the diet on body gain composition and energy utilization in growing pigs. Journal of Animal Science 65, 717–726.
   PubMed Web of Science ®Google Scholar
• Peng, Y.-S., Meliza, L.L., Vavich, M.G. and Kemmerer, A.R. (1974) Changes in food intake and nitrogen metabolism of rats while adapting to a low or high protein diet. Journal of Nutrition 104, 1008–1017.
   PubMed Web of Science ®Google Scholar
• Peters, J.C. and Harper, A.E. (1985) Adaptation of rats to diets containing different levels of protein: effects on food intake, plasma and brain amino acid concentrations and brain neurotransmitter metabolism. Journal of Nutrition 115, 382–398.
   PubMed Web of Science ®Google Scholar
• Ramirez, I. (1989) Resistance to dietary hyperphagia in juvenile rats. Journal of Nutrition 119, 1333–1339.
   PubMed Web of Science ®Google Scholar
• Rothwell, N.J., Stock, M.J. and Tyzbir, R.S. (1983) Mechanisms of thermogenesis induced by low-protein diets. Metabolism 32, 257–261.
   PubMed Web of Science ®Google Scholar
• Rothwell, N.J. and Stock, M.J. (1987) Influence of carbohydrate and fat intake on diet-induced thermogenesis and brown fat activity in rats fed low-protein diets. Journal of Nutrition 117, 1721–1726.
   PubMed Web of Science ®Google Scholar
• Sahu, A., Kalra, P.S. and Kalra, S.P. (1988) Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus. Peptides 9, 83–86.
   PubMed Web of Science ®Google Scholar
• Sanacora, G., Kershaw, M., Finkelstein, J.A. and White, J.D. (1990) Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation. Endocrinology 127, 730–737.
   PubMed Web of Science ®Google Scholar
• Scarpace, P.J., Matheny, M., Pollock, B.H. and Tümer, N. (1997) Leptin increases uncoupling protein expression and energy expenditure. American Journal of Physiology 273, E226–E230.
   PubMed Web of Science ®Google Scholar
• Specter, S.E., Hamilton, J.S., Stern, J.S. and Horwitz, B.A. (1995) Chronic protein restriction does not alter energetic efficiency of brown adipose tissue thermogenic capacity in genetically obese (fa/fa) Zucker rats. Journal of Nutrition 125, 2183–2193.
   PubMed Web of Science ®Google Scholar
• Stanley, B.G., Kyrkouli, S.E., Lampert, S. and Leibowitz, S.F. (1986) Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides 7, 1189–1192.
   PubMed Web of Science ®Google Scholar
• Stanley, B.G. and Leibowitz, S.F. (1985) Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proceedings of the National Academy of Science 82, 3940–3943.
   PubMed Web of Science ®Google Scholar
• Stirling, J.L. and Stock, M.J. (1968) Metabolic origins of thermogenesis induced by diet. Nature 220, 801–802.
   PubMed Web of Science ®Google Scholar
• Swick, R.W. and Gribskov, C.L. (1983) The effect of dietary protein levels on diet-induced thermogenesis in the rat. Journal of Nutrition 113, 2289–2294.
   PubMed Web of Science ®Google Scholar
• Thonney, M.L. and Ross, D.A. (1987) Composition of gain of rats fed low or high protein diets and grown at controlled rates from 80 to 205 grams. Journal of Nutrition 117, 2135–2141.
   PubMed Web of Science ®Google Scholar
• Tulp, O.L. and Horton, E. (1981) Effect of prolonged experimental protein malnutrition and of refeeding on growth, adipose tissue development and body composition in rats. Journal of Nutrition 111, 1145–1156.
   PubMed Web of Science ®Google Scholar
• White, B.D., Dean, R.G. and Martin, R.J. (1990) Adrenalectomy decreases neuropeptide Y mRNA levels in the arcuate nucleus. Brain Research Bulletin 25, 711–715.
   PubMed Web of Science ®Google Scholar
• White, B.D., He, B., Dean, R.G. and Martin, R.J. (1994) Low-protein diets increase neuropeptide Y gene expression in the basomedial hypothalamus of rats. Journal of Nutrition 124, 1152–1160.
   PubMed Web of Science ®Google Scholar
• Youngman, L.D. and Campbell, T.C. (1992) Inhibition of aflatoxin B1-induced gamma-glutamyltranspeptidase positive (GGT+) hepatic preneoplastic foci and tumors by low protein diets: evidence that altered GGT+ foci indicate neoplastic potential. Carcinogenesis 13, 1607–1613.
   PubMed Web of Science ®Google Scholar
• Zhao, J., Unelius, L., Bengtsson, T., Cannon, B. and Nedergaard, J. (1994) Coexisting β-adrenoceptor subtypes: significance for thermogenic process in brown fat cells. American Journal of Physiology 267, C969–C979.
   PubMed Web of Science ®Google Scholar
• Zhao, X.-Q., Jorgensen, H., Gabert, V.M. and Eggum, B.O. (1996) Energy metabolism and protein balance in growing rats housed in 18°C or 28°C environments and fed different levels of dietary protein. Journal of Nutrition 126, 2036–2043.
   PubMed Web of Science ®Google Scholar