Synbiotic supplementation, systemic inflammation, and symptoms of brain disorders in elders: A secondary study from a randomized clinical trial

References

• Franceschi C, Bonafè M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci 2000;908:244–54. doi: 10.1111/j.1749-6632.2000.tb06651.x
   PubMed Web of Science ®Google Scholar
• Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci 2014;69(Suppl 1):S4–9. doi: 10.1093/gerona/glu057
   PubMed Web of Science ®Google Scholar
• Anderson JM. Molecular structure of tight junctions and their role in epithelial transport. News Physiol Sci 2001;16:126–30.
   PubMedGoogle Scholar
• Castanon N, Luheshi G, Layé S. Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity. Front Neuroscience 2015;9:229. doi: 10.3389/fnins.2015.00229
   PubMed Web of Science ®Google Scholar
• Wong SY, Leung JC, Leung PC, Woo J. Depressive symptoms and change in abdominal obesity in the elderly: positive or negative association? Am J Geriatr Psychiatry 2011;19:730–42. doi: 10.1097/JGP.0b013e3181ff63be
   PubMed Web of Science ®Google Scholar
• Manco M, Putignani L, Bottazzo GF. Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. Endocr Rev 2010;31:817–44. doi: 10.1210/er.2009-0030
   PubMed Web of Science ®Google Scholar
• Pendyala S, Walker JM, Holt PR. A high-fat diet is associated with endotoxemia that originates from the gut. Gastroenterology 2012;142:1100–1101. e1102. doi: 10.1053/j.gastro.2012.01.034
   PubMed Web of Science ®Google Scholar
• Kamada N, Chen GY, Inohara N, Núñez G. Control of pathogens and pathobionts by the gut microbiota. Nat Immunol 2013;14:685–90. doi: 10.1038/ni.2608
   PubMed Web of Science ®Google Scholar
• Numakawa T, Richards M, Nakajima S, Adachi N, Furuta M, Odaka H, et al. The role of brain-derived neurotrophic factor in comorbid depression: possible linkage with steroid hormones, cytokines, and nutrition. Front Psychiatry 2014;5:157. doi: 10.3389/fpsyt.2014.00136
   PubMed Web of Science ®Google Scholar
• Bettio LEB, Rajendran L, Gil-Mohapel J. The effects of aging in the hippocampus and cognitive decline. Neurosci Biobehav Rev 2017;79:66–86. doi: 10.1016/j.neubiorev.2017.04.030
   PubMed Web of Science ®Google Scholar
• Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation tosickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008;9:46–56. doi: 10.1038/nrn2297
   PubMed Web of Science ®Google Scholar
• Capuron L, Miller AH. Immune system to brain signaling: neuro psychopharmacological implications. Pharmacol Ther 2011;130:226–38. doi: 10.1016/j.pharmthera.2011.01.014
   PubMed Web of Science ®Google Scholar
• Douglas LC, Sanders ME. Probiotics and prebiotics in dietetics practice. J Am Diet Assoc 2008;108:510–21. doi: 10.1016/j.jada.2007.12.009
   PubMed Web of Science ®Google Scholar
• Magrone T, Jirillo E. The interaction between gut microbiota and age-related changes in immune function and inflammation. Immun Ageing 2013;10:31. doi: 10.1186/1742-4933-10-31
   PubMed Web of Science ®Google Scholar
• Robertson DA, Savva GM, Kenny RA. Frailty and cognitive impairment--a review of the evidence and causal mechanisms. Ageing Res Rev 2013;12:840–51. doi: 10.1016/j.arr.2013.06.004
   PubMed Web of Science ®Google Scholar
• Zhang SM, Tang XD, Yang XR, Zheng RR, Xu L, Wu JH. Relationship between frailty and depression in elderly patients. Zhonghua Yi Xue Za Zhi 2017;97:3384–7.
   PubMedGoogle Scholar
• Ribeiro O, Duarte N, Teixeira L, Paúl C. Frailty and depression in centenarians. Int Psychogeriatr 2017;21:1–10.
   Google Scholar
• Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:M146–56. doi: 10.1093/gerona/56.3.M146
   PubMed Web of Science ®Google Scholar
• Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale (NJ): Lawrence Earlbaum Associates; 1988.
   Google Scholar
• Neto JV, de Melo CM, Ribeiro SML. Effects of three-month intake of synbiotic on inflammation and body composition in the elderly: a pilot study. Nutrients 2013;5:1276–86. doi: 10.3390/nu5041276
   PubMed Web of Science ®Google Scholar
• Kwon HK, Kim GC, Kim Y, Hwang W, Jash A, Sahoo A, Kim JE, Nam JH, Im SH. Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response. Clin Immunol 2013;146:217–27. doi: 10.1016/j.clim.2013.01.001
   PubMed Web of Science ®Google Scholar
• Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Nat Acad Sci of USA 2011;108:16050–5. doi: 10.1073/pnas.1102999108
   PubMed Web of Science ®Google Scholar
• Desbonnet L, Garrett L, Clarke G, Bienenstock J, Dinan TG. The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat. J Psychiatric Res 2008;43:164–74. doi: 10.1016/j.jpsychires.2008.03.009
   PubMed Web of Science ®Google Scholar
• Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 2010;170:1179–88. doi: 10.1016/j.neuroscience.2010.08.005
   PubMed Web of Science ®Google Scholar
• Kearney SM, Gibbons SM. Designing synbiotics for improved human health. Microb Biotechnol. 2018;11:141–4. [Epub ahead of print]. doi: 10.1111/1751-7915.12885
   PubMed Web of Science ®Google Scholar
• Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17:37–49. doi: 10.1016/0022-3956(82)90033-4
   PubMed Web of Science ®Google Scholar
• Paradela EMP, Lourenço RA, Veras RP. Validação da escala de depressão geriátrica em um ambulatório geral. Rev Saúde Pública 2005;39:6. doi: 10.1590/S0034-89102005000600008
   Google Scholar
• Brucki SM, Nitrini R, Caramelli P, Bertolucci PH, Okamoto I. Suggestions for utilization of the mini-mental state examination in Brazil. Arq Neuropsiquiatr 2003;61:777–81. doi: 10.1590/S0004-282X2003000500014
   PubMed Web of Science ®Google Scholar
• Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of major depression. Trend Immunol 2006;27:24–31. doi: 10.1016/j.it.2005.11.006
   PubMed Web of Science ®Google Scholar
• Wilson CJ, Finch CE, Cohen HJ. Cytokines and cognition-the case for a head-to-toe inflammatory paradigm. J Am Geriatr Soc 2002;50:2041–56. doi: 10.1046/j.1532-5415.2002.50619.x
   PubMed Web of Science ®Google Scholar
• Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 2009;65:732–41. doi: 10.1016/j.biopsych.2008.11.029
   PubMed Web of Science ®Google Scholar
• Charlton RA, Lamar M, Zhang A, Ren X, Ajilore O, Pandey GN, et al. Associations between pro-inflammatory cytokines, learning, and memory in late-life depression and healthy aging. Int J Geriatr Psychiatry. 2017. doi:10.1002/gps.4686. [Epub ahead of print].
   PubMed Web of Science ®Google Scholar
• Bollen J, Trick L, Llewellyn D, Dickens C. The effects of acute inflammation on cognitive functioning and emotional processing in humans: a systematic review of experimental studies. J Psychosom Res 2017;94:47–55. doi: 10.1016/j.jpsychores.2017.01.002
   PubMed Web of Science ®Google Scholar
• Weaver JD, Huang MH, Albert M, Harris T, Rowe JW, Seeman TE. Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology 2002;59:371–8. doi: 10.1212/WNL.59.3.371
   PubMed Web of Science ®Google Scholar
• Economos A, Wright CB, Yeseon PM, Rundek T, Rabbani L, et al MD. Interleukin 6 plasma concentration associates with cognitive. Decline: The Northern Manhattan study. Neuroepidemiology 2013;40:253–9. doi: 10.1159/000343276
   PubMed Web of Science ®Google Scholar
• Marques AH, Cizza G, Sternberg E. Interações imunocerebrais e implicações nos transtornos psiquiátricos. Brain-immune interactions and implications in psychiatric disorders. Rev Bras Psiquiatr 2007;29(supl I):S27–32. doi: 10.1590/S1516-44462007000500006
   PubMedGoogle Scholar
• Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, et al. A meta-analysis of cytokines in major depression. Biol Psychiatry 2010;67:446–57. doi: 10.1016/j.biopsych.2009.09.033
   PubMed Web of Science ®Google Scholar
• Minciullo PL, Catalano A, Mandraffino G, Casciaro M, Crucitti A, Maltese G, et al. Inflammaging and anti-inflammaging: the role of cytokines in extreme longevity. Arch Immunol Ther Exp (Warsz). 2016;64: 111–26. doi: 10.1007/s00005-015-0377-3
   PubMed Web of Science ®Google Scholar
• Khairova RA, Machado-Vieira R, Du J, Manji HK. A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder. Int J Neuropsychopharmacol 2009;12(4):561–78. doi: 10.1017/S1461145709009924
   PubMed Web of Science ®Google Scholar
• Hiles SA, Baker AL, de Malmanche T, Attia J. A meta-analysis of differences in IL-6 and IL-10 between people with and without depression: exploring the causes of heterogeneity. Brain Behav Immun 2012;26:1180–8. doi: 10.1016/j.bbi.2012.06.001
   PubMed Web of Science ®Google Scholar
• Song WB, Lv YH, Zhang ZS, Li YN, Xiao LP, Yu XP, et al. Soluble intercellular adhesion molecule-1, D-lactate and diamine oxidase in patients with inflammatory bowel disease. World J Gastroenterol 2009;15:3916–9. doi: 10.3748/wjg.15.3916
   PubMed Web of Science ®Google Scholar
• Wang L, Llorente C, Hartmann P, Yang AM, Chen P, Schnabl B. Methods to determine intestinal permeability and bacterial translocation during liver disease. J Immunol Methods 2015;421:44–53. doi: 10.1016/j.jim.2014.12.015
   PubMed Web of Science ®Google Scholar
• Grootjans J, Thuijls G, Verdam F, Derikx JP, Lenaerts K, Buurman WA. Non-invasive assessment of barrier integrity and function of the human gut. World J Gastrointest Surg 2010;2:61–9. doi: 10.4240/wjgs.v2.i3.61
   PubMedGoogle Scholar
• Galipeau HJ, Verdu EF. The complex task of measuring intestinal permeability in basic and clinical science. Neurogastroenterol Motil 2016;28:957–65. doi: 10.1111/nmo.12871
   PubMed Web of Science ®Google Scholar
• Hippe B, Zwielehner J, Liszt K, Lassl C, Unger F, Haslberger AG. Quantification of butyryl CoA:acetate CoA-transferase genes reveals different butyrate production capacity in individuals according to diet and age. FEMS Microbiol Lett 2011;316:130–5. doi: 10.1111/j.1574-6968.2010.02197.x
   PubMed Web of Science ®Google Scholar
• Lebeer S, Vanderleyden J, De Keersmaecker S. Host interactions of probiotic bacterial surface molecule: comparison with commensals and pathogens. Nature Reviews Microbiolog 2010;8:171–84. doi: 10.1038/nrmicro2297
   PubMed Web of Science ®Google Scholar
• Zoetendal EG, von Wright A, Vilpponen-Salmela T, Ben-Amor K, Akkermans AD, de Vos WM. Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol 2002;68:3401–7. doi: 10.1128/AEM.68.7.3401-3407.2002
   PubMed Web of Science ®Google Scholar