Nutrient infusion evoked magnetic resonance imaging signal in the human hypothalamus

References

• Mayer EA, Tillisch K, Gupta A. Gut/brain axis and the microbiota. J Clin Invest. 2015;125(3):926–38. doi:10.1172/JCI76304.
   PubMed Web of Science ®Google Scholar
• Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015;28(2):203–9.
   PubMed Web of Science ®Google Scholar
• Raka F, Farr S, Kelly J, Stoianov A, Adeli K. Metabolic control via nutrient-sensing mechanisms: role of taste receptors and the gut-brain neuroendocrine axis. Am J Physiol Endocrinol Metab. 2019;317(4):E559–E572. doi:10.1152/ajpendo.00036.2019.
   PubMed Web of Science ®Google Scholar
• Kaelberer MM, Rupprecht LE, Liu WW, Weng P, Bohórquez DV. Neuropod cells: The emerging biology of gut-brain sensory transduction. Annu Rev Neurosci. 2020;43:337–53. doi:10.1146/annurev-neuro-091619-022657.
   PubMed Web of Science ®Google Scholar
• Williams EK, Chang RB, Strochlic DE, Umans BD, Lowell BB, Liberles SD. Sensory neurons that detect stretch and nutrients in the digestive system. Cell. 2016;166(1):209–21. doi:10.1016/j.cell.2016.05.011.
   PubMed Web of Science ®Google Scholar
• Tan H-E, Sisti AC, Jin H, Vignovich M, Villavicencio M, Tsang KS, et al. The gut-brain axis mediates sugar preference. Nature. 2020;580(7804):511–6. doi:10.1038/s41586-020-2199-7.
   PubMed Web of Science ®Google Scholar
• Han W, Tellez LA, Perkins MH, Perez IO, Qu T, Ferreira J, et al. A neural circuit for gut-induced reward. Cell. 2018;175(3):665–78.e23. doi:10.1016/j.cell.2018.08.049.
   PubMed Web of Science ®Google Scholar
• Tsurugizawa T, Uneyama H, Torii K. Brain amino acid sensing. Diabetes Obes Metab. 2014;16(Suppl 1):41–8. doi:10.1111/dom.12336.
   PubMedGoogle Scholar
• Clemmensen C, Müller TD, Woods SC, Berthoud H-R, Seeley RJ, Tschöp MH. Gut-brain cross-talk in metabolic control. Cell. 2017;168(5):758–74. doi:10.1016/j.cell.2017.01.025.
   PubMed Web of Science ®Google Scholar
• Livovsky DM, Pribic T, Azpiroz F. Food, eating, and the gastrointestinal tract. Nutrients MDPI. 2020;12(4):986), doi:10.3390/nu12040986.
   Web of Science ®Google Scholar
• Yu CD, Xu QJ, Chang RB. Vagal sensory neurons and gut-brain signaling. Curr Opin Neurobiol. 2020;62:133–40. doi:10.1016/j.conb.2020.03.006.
   PubMed Web of Science ®Google Scholar
• Alhadeff AL. Monitoring in vivo neural activity to understand gut-brain signaling. Endocrinology. 2021;162(5). doi:10.1210/endocr/bqab029.
   PubMed Web of Science ®Google Scholar
• Duca FA, Waise TMZ, Peppler WT, Lam TKT. The metabolic impact of small intestinal nutrient sensing. Nat Commun. 2021;12(1):903. doi:10.1038/s41467-021-21235-y.
   PubMed Web of Science ®Google Scholar
• Heeley N, Blouet C. Central amino acid sensing in the control of feeding behavior. Front Endocrinol (Lausanne. 2016;7:148. doi:10.3389/fendo.2016.00148.
   PubMed Web of Science ®Google Scholar
• Kumar U, Singh S. Role of somatostatin in the regulation of central and peripheral factors of satiety and obesity. Int J Mol Sci. 2020;21(7). doi:10.3390/ijms21072568.
   Web of Science ®Google Scholar
• Moura-Assis A, Friedman JM, Velloso LA. Gut-to-brain signals in feeding control. Am J Physiol Endocrinol Metab. 2021;320(2):E326–E332. doi:10.1152/ajpendo.00388.2020.
   PubMed Web of Science ®Google Scholar
• Frank S, Linder K, Kullmann S, Heni M, Ketterer C, Cavusoglu M, et al. Fat intake modulates cerebral blood flow in homeostatic and gustatory brain areas in humans. Am J Clin Nutr. 2012;95(6):1342–9. doi:10.3945/ajcn.111.031492.
   PubMed Web of Science ®Google Scholar
• Page KA, Chan O, Arora J, Belfort-Deaguiar R, Dzuira J, Roehmholdt B, et al. Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways. JAMA. 2013;309(1):63–70. doi:10.1001/jama.2012.116975.
   PubMed Web of Science ®Google Scholar
• Van Oudenhove L, McKie S, Lassman D, Uddin B, Paine P, Coen S, et al. Fatty acid-induced gut-brain signaling attenuates neural and behavioral effects of sad emotion in humans. J Clin Invest. 2011;121(8):3094–9. doi:10.1172/JCI46380.
   PubMed Web of Science ®Google Scholar
• Spetter MS, de Graaf C, Mars M, Viergever MA, Smeets PAM. The sum of its parts–effects of gastric distention, nutrient content and sensory stimulation on brain activation. PLoS One. 2014;9(3):e90872. doi:10.1371/journal.pone.0090872.
   PubMed Web of Science ®Google Scholar
• Simon JJ, Stopyra MA, Mönning E, Sailer S, Lavandier N, Kihm LP, et al. Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity. J Clin Invest. 2020;130(8):4094–103. doi:10.1172/JCI136782.
   PubMed Web of Science ®Google Scholar
• Little TJ, McKie S, Jones RB, D’Amato M, Smith C, Kiss O, et al. Mapping glucose-mediated gut-to-brain signalling pathways in humans. Neuroimage. 2014;96:1–11. doi:10.1016/j.neuroimage.2014.03.059.
   PubMed Web of Science ®Google Scholar
• Lassman DJ, McKie S, Gregory LJ, Lal S, D’Amato M, Steele I, et al. Defining the role of cholecystokinin in the lipid-induced human brain activation matrix. Gastroenterology. 2010;138(4):1514–24. doi:10.1053/j.gastro.2009.12.060.
   PubMed Web of Science ®Google Scholar
• van Opstal AM, Kaal I, van den Berg-Huysmans AA, Hoeksma M, Blonk C, Pijl H, Rombouts S a. RB, van der Grond J. Dietary sugars and non-caloric sweeteners elicit different homeostatic and hedonic responses in the brain. Nutrition. 2019;60:80–6. doi:10.1016/j.nut.2018.09.004.
   PubMed Web of Science ®Google Scholar
• Smeets PAM, Vidarsdottir S, de Graaf C, Stafleu A, van Osch MJP, Viergever MA, et al. Oral glucose intake inhibits hypothalamic neuronal activity more effectively than glucose infusion. Am J Physiol Endocrinol Metab. 2007;293(3):E754–758. doi:10.1152/ajpendo.00231.2007.
   PubMed Web of Science ®Google Scholar
• Osada T, Suzuki R, Ogawa A, Tanaka M, Hori M, Aoki S, et al. Functional subdivisions of the hypothalamus using areal parcellation and their signal changes related to glucose metabolism. Neuroimage. 2017;162:1–12. doi:10.1016/j.neuroimage.2017.08.056.
   PubMed Web of Science ®Google Scholar
• Frank-Podlech S, Heinze JM, Machann J, Scheffler K, Camps G, Fritsche A, et al. Functional connectivity within the gustatory network is altered by fat content and oral fat sensitivity - A pilot study. Front Neurosci. 2019;13:725. doi:10.3389/fnins.2019.00725.
   PubMed Web of Science ®Google Scholar
• Al-Zubaidi A, Heldmann M, Mertins A, Jauch-Chara K, Münte TF. Influences of hunger, satiety and oral glucose on functional brain connectivity: A multimethod resting-state fMRI study. Neuroscience. 2018;382:80–92. doi:10.1016/j.neuroscience.2018.04.029.
   PubMed Web of Science ®Google Scholar
• Li J, An R, Zhang Y, Li X, Wang S. Correlations of macronutrient-induced functional magnetic resonance imaging signal changes in human brain and gut hormone responses. Am J Clin Nutr. 2012;96(2):275–82. doi:10.3945/ajcn.112.037440.
   PubMed Web of Science ®Google Scholar
• de Araujo IE, Schatzker M, Small DM. Rethinking food reward. Annu Rev Psychol. 2020;71:139–64. doi:10.1146/annurev-psych-122216-011643.
   PubMed Web of Science ®Google Scholar
• Chen JJ, Jann K, Wang DJJ. Characterizing resting-state brain function using arterial spin labeling. Brain Connect. 2015;5(9):527–42. doi:10.1089/brain.2015.0344.
   PubMed Web of Science ®Google Scholar
• Chappell MA, Groves AR, Whitcher B, Woolrich MW. Variational Bayesian inference for a nonlinear forward model. IEEE Trans Signal Process. 2009;57(1):223–36. doi:10.1109/TSP.2008.2005752.
   Web of Science ®Google Scholar
• Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage. 2003;19(3):1233–9. doi:10.1016/s1053-8119(03)00169-1.
   PubMed Web of Science ®Google Scholar
• Tsurugizawa T, Uematsu A, Nakamura E, Hasumura M, Hirota M, Kondoh T, et al. Mechanisms of neural response to gastrointestinal nutritive stimuli: the gut-brain axis. Gastroenterology. 2009;137(1):262–73. doi:10.1053/j.gastro.2009.02.057.
   PubMed Web of Science ®Google Scholar
• Hurley SW, Johnson AK. The role of the lateral hypothalamus and orexin in ingestive behavior: a model for the translation of past experience and sensed deficits into motivated behaviors. Front Syst Neurosci. 2014;8:216. doi:10.3389/fnsys.2014.00216.
   PubMedGoogle Scholar
• Talakoub O, Paiva RR, Milosevic M, Hoexter MQ, Franco R, Alho E, et al. Lateral hypothalamic activity indicates hunger and satiety states in humans. Ann Clin Transl Neurol. 2017;4(12):897–901. doi:10.1002/acn3.466.
   PubMed Web of Science ®Google Scholar