Publication Cover
Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 26, 2023 - Issue 3
387
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Regional brain morphology of the primary somatosensory cortex correlates with spicy food consumption and capsaicin sensitivity

ORCID Icon, , &

References

  • Calixto JB, Kassuya CA, André E, Ferreira J. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol Ther. 2005;106(2):179–208.
  • Caterina MJ, Julius D. Sense and specificity: a molecular identity for nociceptors. Curr Opin Neurobiol. 1999;9(5):525–30.
  • Simons CT, Klein AH, Carstens E. Chemogenic subqualities of mouthfeel. Chem Senses. 2019;44(5):281–8.
  • Poletti SC, Hausold J, Herrmann A, Witt M, Hummel T. Topographical distribution of trigeminal receptor expression in the nasal cavity. Rhinology. 2019;57(2):147–52.
  • Jahng JW, Moon YW, Lee J-H. Immunohistochemical detection of capsaicin receptors in taste cells of human circumvallate papillae. Asian J Oral Maxillofac Surg. 2010;22(4):193–7.
  • Rudenga K, Green B, Nachtigal D, Small DM. Evidence for an integrated oral sensory module in the human anterior ventral insula. Chem Senses. 2010;35(8):693–703.
  • Kawakami S, Sato H, Sasaki AT, Tanabe HC, Yoshida Y, Saito M, et al. The brain mechanisms underlying the perception of pungent taste of capsaicin and the subsequent autonomic responses. Front Hum Neurosci. 2015;9:720.
  • Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain. 2005;9(4):463–84.
  • Trachtenberg JT, Chen BE, Knott GW, Feng G, Sanes JR, Welker E, et al. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature. 2002;420(6917):788–94.
  • Teutsch S, Herken W, Bingel U, Schoell E, et al. Changes in brain gray matter due to repetitive painful stimulation. Neuroimage. 2008;42(2):845–9.
  • Emerson NM, Zeidan F, Lobanov OV, Hadsel MS, Martucci KT, Quevedo AS, et al. Pain sensitivity is inversely related to regional grey matter density in the brain. Pain. 2014;155(3):566–73.
  • Su T, Gao X, Li H, Zhang L, Han P, Chen H. Frequent spicy food consumption is associated with reduced capsaicin and salty taste sensitivity but unchanged sour taste or intranasal trigeminal sensitivity. Food Qual Prefer. 2022;96:104411.
  • Nolden AA, Hayes JE. Perceptual and affective responses to sampled capsaicin differ by reported intake. Food Qual Prefer. 2017;55:26–34.
  • Wen Q, Wei Y, Du H, Lv J, Guo Y, Bian Z, et al. Characteristics of spicy food consumption and its relation to lifestyle behaviours: results from 0.5 million adults. Int J Food Sci Nutr. 2021;72(4):569–76.
  • Albrecht J, Kopietz R, Frasnelli J, Wiesmann M, Hummel T, Lundstrom JN. The neuronal correlates of intranasal trigeminal function-an ALE meta-analysis of human functional brain imaging data. Brain Res Rev. 2010;62(2):183–96.
  • Hummel T, Oehme L, van den Hoff J, Gerber J, Heinke M, Boyle JA, et al. PET-based investigation of cerebral activation following intranasal trigeminal stimulation. Hum Brain Mapp. 2009;30(4):1100–4.
  • Kollndorfer K, Kowalczyk K, Frasnelli J, Hoche E, Unger E, Mueller CA, et al. Same same but different. Different trigeminal chemoreceptors share the same central pathway. PLoS One. 2015;10(3):e0121091.
  • Ashburner J, Friston KJ. Voxel-based morphometry – the methods. Neuroimage. 2000;11(6 Pt 1):805–21.
  • Woo CW, Krishnan A, Wager TD. Cluster-extent based thresholding in fMRI analyses: pitfalls and recommendations. Neuroimage. 2014;91:412–9.
  • Lieberman MD, Cunningham WA. Type i and Type II error concerns in fMRI research: re-balancing the scale. Soc Cogn Affect Neurosci. 2009;4(4):423–8.
  • Forman SD, Cohen JD, Fitzgerald M, Eddy WF, Mintun MA, Noll DC. Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold. Magn Reson Med. 1995;33(5):636–47.
  • Song XW, Dong ZY, Long XY, Li XF, Zuo XN, Zhu CZ, et al. REST: a toolkit for resting-state functional magnetic resonance imaging data processing. PLoS One. 2011;6(9):e25031.
  • Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15(1):273–89.
  • Smutzer G, Jacob JC, Tran JT, Shah DI, Gambhir S, Devassy RK, et al. Detection and modulation of capsaicin perception in the human oral cavity. Physiol Behav. 2018;194:120–31.
  • Fukunaga A, Uematsu H, Sugimoto K. Influences of aging on taste perception and oral somatic sensation. J Gerontol A Biol Sci Med Sci. 2005;60(1):109–13.
  • Byrnes NK, Hayes JE. Personality factors predict spicy food liking and intake. Food Qual Prefer. 2013;28(1):213–21.
  • Frasnelli J, Hummel T, Berg J, Huang G, Doty RL. Intranasal localizability of odorants: influence of stimulus volume. Chem Senses. 2011;36(4):405–10.
  • Frasnelli J, Albrecht J, Bryant B, Lundstrom JN. Perception of specific trigeminal chemosensory agonists. Neuroscience. 2011;189:377–83.
  • Byrnes N, Nestrud MA, Hayes JE. Perceptual mapping of chemesthetic stimuli in naive assessors. Chemosens Percept. 2015;8(1):19–32.
  • Piochi M, Cabrino G, Morini G, Torri L. Individual differences in the perception of orthonasal irritation induced by food. Appetite. 2019;144:104460.
  • Xu A, Larsen B, Baller EB, Scott JC, Sharma V, Adebimpe A, et al. Convergent neural representations of experimentally-induced acute pain in healthy volunteers: a large-scale fMRI meta-analysis. Neurosci Biobehav Rev. 2020;112:300–23.
  • Aroke EN, Powell-Roach KL, Jaime-Lara RB, Tesfaye M, Roy A, Jackson P, et al. Taste the pain: the role of TRP channels in pain and taste perception. Int J Mol Sci. 2020;21(16).
  • Niddam DM, Wang SJ, Tsai SY. Pain sensitivity and the primary sensorimotor cortices: a multimodal neuroimaging study. Pain. 2021;162(3):846–55.
  • Draganski B, May A. Training-induced structural changes in the adult human brain. Behav Brain Res. 2008;192(1):137–42.
  • Kong J, White NS, Kwong KK, Vangel MG, Rosman IS, Gracely RH, et al. Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity. Hum Brain Mapp. 2006;27(9):715–21.
  • de Araujo IE, Simon SA. The gustatory cortex and multisensory integration. Int J Obes. 2009;33(Suppl 2):S34–43.
  • Everaerts W, Gees M, Alpizar YA, Farre R, Leten C, Apetrei A, et al. The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil. Curr Biol. 2011;21(4):316–21.
  • Gees M, Alpizar YA, Boonen B, Sanchez A, Everaerts W, Segal A, et al. Mechanisms of transient receptor potential vanilloid 1 activation and sensitization by allyl isothiocyanate. Mol Pharmacol. 2013;84(3):325–34.
  • Defrin R, Dekel-Steinkeller M, Urca G. Some like it hot: preference for temperature and pungency consumption is associated with sensitivity to noxious heat. Eur J Pain. 2020;25(2):473–84.
  • Scheibe M, Schmidt A, Hummel T. Investigation of the topographical differences in somatosensory sensitivity of the human nasal mucosa. Rhinology. 2012;50(3):290–3.
  • Scheibe M, van Thriel C, Hummel T. Responses to trigeminal irritants at different locations of the human nasal mucosa. Laryngoscope. 2008;118(1):152–5.
  • Prescott J, Stevenson RJ. Effects of oral chemical irritation on tastes and flavors in frequent and infrequent users of chili. Physiol Behav. 1995;58(6):1117–27.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.