Mood disturbance, but not overall diet quality, is associated with fecal microbiome diversity in free-living adults

References

• Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):617–27. doi:10.1001/archpsyc.62.6.617.
   PubMed Web of Science ®Google Scholar
• Rakofsky J, Rapaport M. Mood disorders. Continuum. 2018;24(3):804–27. doi:10.1212/con.0000000000000604.
   PubMedGoogle Scholar
• World Health Organization. World report on disability 2011. World Health Organization; 2011.
   Google Scholar
• Khan HA, Knusel KD, Calabrese JR, Salas-Vega S. Direct incremental healthcare costs associated with mood disorders in the United States, 2007–2017. J Affect Disord. 2020;273:304–9. doi:10.1016/j.jad.2020.03.127.
   PubMed Web of Science ®Google Scholar
• Ramic E, Prasko S, Gavran L, Spahic E. Assessment of the antidepressant side effects occurrence in patients treated in primary care. Mater Sociomed. 2020;32(2):131–4. doi:10.5455/msm.2020.32.131-134.
   PubMedGoogle Scholar
• Wang SM, Han C, Bahk WM, Lee SJ, Patkar AA, Masand PS, Pae CU. Addressing the side effects of contemporary antidepressant drugs: a comprehensive review. Chonnam Med J. 2018;54(2):101–12.
   PubMedGoogle Scholar
• Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015;28(2):203–9.
   PubMed Web of Science ®Google Scholar
• Flowers SA, Ellingrod VL. The microbiome in mental health: potential contribution of gut microbiota in disease and pharmacotherapy management. Pharmacother J Hum Pharmacol Drug Ther. 2015;35(10):910–6. doi:10.1002/phar.1640.
   Google Scholar
• Margolis KG, Cryan JF, Mayer EA. The microbiota-gut-brain axis: from motility to mood. Gastroenterology. 2021;160(5):1486–501. doi:10.1053/j.gastro.2020.10.066.
   PubMed Web of Science ®Google Scholar
• Cryan JF, O’Mahony SM. The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterol Motil. 2011;23(3):187–92. doi:10.1111/j.1365-2982.2010.01664.x.
   PubMed Web of Science ®Google Scholar
• Grenham S, Clarke G, Cryan J, Dinan T. Brain–gut–microbe communication in health and disease. Front Physiol. 2011;2. doi:10.3389/fphys.2011.00094.
   PubMed Web of Science ®Google Scholar
• Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012;13(10):701–12. doi:10.1038/nrn3346.
   PubMed Web of Science ®Google Scholar
• Huang T-T, Lai J-B, Du Y-L, Xu Y, Ruan L-M, Hu S-H. Current understanding of gut microbiota in mood disorders: an update of human studies. Front Genet. 2019;10. doi:10.3389/fgene.2019.00098.
   Web of Science ®Google Scholar
• Collins SM, Surette M, Bercik P. The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol. 2012;10(11):735–42. doi:10.1038/nrmicro2876.
   PubMed Web of Science ®Google Scholar
• Kennedy PJ, Cryan JF, Dinan TG, Clarke G. Irritable bowel syndrome: a microbiome-gut-brain axis disorder? World J Gastroenterol. 2014;20(39):14105–25. doi:10.3748/wjg.v20.i39.14105.
   PubMed Web of Science ®Google Scholar
• Jiang H-Y, Zhang X, Yu Z-H, et al. Altered gut microbiota profile in patients with generalized anxiety disorder. J Psychiatr Res. 2018;104:130–6. doi:10.1016/j.jpsychires.2018.07.007.
   PubMed Web of Science ®Google Scholar
• Jiang H, Ling Z, Zhang Y, et al. Altered fecal microbiota composition in patients with major depressive disorder. Brain Behav Immun. 2015;48:186–94. doi:10.1016/j.bbi.2015.03.016.
   PubMed Web of Science ®Google Scholar
• Neuendorf R, Harding A, Stello N, Hanes D, Wahbeh H. Depression and anxiety in patients with inflammatory bowel disease: a systematic review. J Psychosom Res. 2016;87:70–80. doi:10.1016/j.jpsychores.2016.06.001.
   PubMed Web of Science ®Google Scholar
• McNair DM. Profile of mood states. Educational and Industrial Testing Service; 1992.
   Google Scholar
• Flint HJ, Duncan SH, Scott KP, Louis P. Links between diet, gut microbiota composition and gut metabolism. Proc Nutr Soc. 2015;74(1):13–22. doi:10.1017/S0029665114001463.
   PubMed Web of Science ®Google Scholar
• Banikazemi Z, Mokhber N, Safarian M, et al. Dietary vitamin E and fat intake are related to beck's depression score. Clin Nutr ESPEN. 2015;10(2):e61–e65.
   PubMedGoogle Scholar
• Su K-P, Matsuoka Y, Pae C-U. Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders. Clin Psychopharmacol Neurosci. 2015;13(2):129.
   PubMed Web of Science ®Google Scholar
• Walker AW, Ince J, Duncan SH, et al. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J. 2011;5(2):220–30. doi:10.1038/ismej.2010.118.
   PubMed Web of Science ®Google Scholar
• Lassale C, Batty GD, Baghdadli A, et al. Healthy dietary indices and risk of depressive outcomes: asystematic review and meta-analysis of observational studies. Mol Psychiatry. 2019;24(7):965–86. doi:10.1038/s41380-018-0237-8.
   PubMed Web of Science ®Google Scholar
• Sánchez-Villegas A, Verberne L, De Irala J, et al. Dietary fat intake and the risk of depression: the SUN project. PLoS One. 2011;6(1):e16268. doi:10.1371/journal.pone.0016268.
   PubMed Web of Science ®Google Scholar
• Salari-Moghaddam A, Saneei P, Larijani B, Esmaillzadeh A. Glycemic index, glycemic load, and depression: a systematic review and meta-analysis. Eur J Clin Nutr. 2019;73(3):356–65. doi:10.1038/s41430-018-0258-z.
   PubMed Web of Science ®Google Scholar
• Lamb DA, Moore JH, Smith MA, et al. The effects of resistance training with or without peanut protein supplementation on skeletal muscle and strength adaptations in older individuals. J Int Soc Sports Nutr. 2020;17(1):66. doi:10.1186/s12970-020-00397-y.
   PubMed Web of Science ®Google Scholar
• Fruge AD, Smith KS, Riviere AJ, et al. Primary outcomes of a randomized controlled crossover trial to explore the effects of a high chlorophyll dietary intervention to reduce colon cancer risk in adults: the meat and three greens (M3G) feasibility trial. Nutrients. 2019;11(10). doi:10.3390/nu11102349.
   Web of Science ®Google Scholar
• Frugé AD, Smith KS, Riviere AJ, et al. A dietary intervention high in green leafy vegetables reduces oxidative DNA damage in adults at increased risk of colorectal cancer: biological outcomes of the randomized controlled meat and three greens (M3G) feasibility trial. Nutrients. 2021;13(4):1220.
   PubMed Web of Science ®Google Scholar
• Kumar R, Eipers P, Little RB, et al. Getting started with microbiome analysis: sample acquisition to bioinformatics. Curr Protoc Hum Genet. 2014;82:18.8.1–29. doi:10.1002/0471142905.hg1808s82.
   PubMedGoogle Scholar
• Van Der Pol WJ, Kumar R, Morrow CD, et al. In silico and experimental evaluation of primer sets for species-level resolution of the vaginal microbiota using 16S ribosomal RNA gene sequencing. J Infect Dis. 2019;219(2):305–14. doi:10.1093/infdis/jiy508.
   PubMed Web of Science ®Google Scholar
• Subar AF, Kirkpatrick SI, Mittl B, et al. The automated self-administered 24-hour dietary recall (ASA24): a resource for researchers, clinicians, and educators from the national cancer institute. J Acad Nutr Diet. 2012;112(8):1134–7. doi:10.1016/j.jand.2012.04.016.
   PubMed Web of Science ®Google Scholar
• Krebs-Smith SM, Pannucci TE, Subar AF, et al. Update of the healthy eating index: HEI-2015. J Acad Nutr Diet. 2018;118(9):1591–602. doi:10.1016/j.jand.2018.05.021.
   PubMed Web of Science ®Google Scholar
• Grove JR, Prapavessis H. Preliminary evidence for the reliability and validity of an abbreviated profile of mood states. Int J Sport Psychol. 1992;23(2):93–109.
   Web of Science ®Google Scholar
• Hayes AF. Introduction to mediation, moderation, and conditional process analysis. 3rd ed. New York, NY, USA: Guilford Press; 2022.
   Google Scholar
• Rea LM, Parker RA. Designing and conducting survey research: a comprehensive guide. 4th ed. San Francisco, CA, USA: Jossey-Bass; 2014.
   Google Scholar
• Huang Y, Shi X, Li Z, et al. Possible association of firmicutes in the gut microbiota of patients with major depressive disorder. Neuropsychiatr Dis Treat. 2018;14:3329–37. doi:10.2147/NDT.S188340.
   PubMed Web of Science ®Google Scholar
• Spielman LJ, Gibson DL, Klegeris A. Unhealthy gut, unhealthy brain: the role of the intestinal microbiota in neurodegenerative diseases. Neurochem Int. 2018;120:149–63. doi:10.1016/j.neuint.2018.08.005.
   PubMed Web of Science ®Google Scholar
• Levy RL, Olden KW, Naliboff BD, et al. Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology. 2006;130(5):1447–58. doi:10.1053/j.gastro.2005.11.057.
   PubMed Web of Science ®Google Scholar
• Wong ML, Inserra A, Lewis MD, et al. Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition. Mol Psychiatry. 2016;21(6):797–805. doi:10.1038/mp.2016.46.
   PubMed Web of Science ®Google Scholar
• Filosa S, Di Meo F, Crispi S. Polyphenols-gut microbiota interplay and brain neuromodulation. Neural Regen Res. 2018;13(12):2055–9. doi:10.4103/1673-5374.241429.
   PubMed Web of Science ®Google Scholar
• Serra D, Almeida LM, Dinis TCP. Dietary polyphenols: a novel strategy to modulate microbiota-gut-brain axis. Trends Food Sci Technol. 2018;78:224–33. doi:10.1016/j.tifs.2018.06.007.
   Web of Science ®Google Scholar
• Shin J-H, Kim C-S, Cha L, et al. Consumption of 85% cocoa dark chocolate improves mood in association with gut microbial changes in healthy adults: a randomized controlled trial. J Nutr Biochem. 2022;99:108854. doi:10.1016/j.jnutbio.2021.108854.
   PubMed Web of Science ®Google Scholar
• US Department of Agriculture and Food and Nutrition Service. Average Healthy Eating Index-2015 scores for adults by age groups. NHANES 2017–2018. 2021.
   Google Scholar
• Wade AT, Davis CR, Dyer KA, et al. A Mediterranean diet supplemented with dairy foods improves mood and processing speed in an Australian sample: results from the MedDairy randomized controlled trial. Nutr Neurosci. 2020;23(8):646–58. doi:10.1080/1028415X.2018.1543148.
   PubMed Web of Science ®Google Scholar
• Francis HM, Stevenson RJ, Chambers JR, Gupta D, Newey B, Lim CK. A brief diet intervention can reduce symptoms of depression in young adults – a randomised controlled trial. PLoS One. 2019;14(10):e0222768. doi:10.1371/journal.pone.0222768.
   PubMed Web of Science ®Google Scholar
• Torres SJ, Nowson CA. A moderate-sodium DASH-type diet improves mood in postmenopausal women. Nutrition. 2012;28(9):896–900. doi:10.1016/j.nut.2011.11.029.
   PubMed Web of Science ®Google Scholar
• Maldonado-Contreras A, Noel SE, Ward DV, Velez M, Mangano KM. Associations between diet, the gut microbiome, and short-chain fatty acid production among older Caribbean Latino adults. J Acad Nutr Diet. 2020;120(12):2047–60.e6. doi:10.1016/j.jand.2020.04.018.
   PubMed Web of Science ®Google Scholar
• Hiza HAB, Casavale KO, Guenther PM, Davis CA. Diet quality of Americans differs by age, sex, race/ethnicity, income, and education level. J Acad Nutr Diet. 2013;113(2):297–306. doi:10.1016/j.jand.2012.08.011.
   PubMed Web of Science ®Google Scholar
• Kivimäki M, Batty GD, Pentti J, et al. Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study. Lancet Public Health. 2020;5(3):e140–e149. doi:10.1016/S2468-2667(19)30248-8.
   PubMed Web of Science ®Google Scholar
• Amato KR, Arrieta M-C, Azad MB, et al. The human gut microbiome and health inequities. Proc Natl Acad Sci USA. 2021;118(25):e2017947118. doi:10.1073/pnas.2017947118.
   PubMed Web of Science ®Google Scholar
• Miller GE, Engen PA, Gillevet PM, et al. Lower neighborhood socioeconomic status associated with reduced diversity of the colonic microbiota in healthy adults. PLoS One. 2016;11(2):e0148952. doi:10.1371/journal.pone.0148952.
   PubMed Web of Science ®Google Scholar
• Colby S, Ortman JM. Projections of the size and composition of the US population: 2014 to 2060. 2015.
   Google Scholar
• Dinan TG, Stanton C, Cryan JF. Psychobiotics: a novel class of psychotropic. Biol Psychiatry. 2013;74(10):720–6. doi:10.1016/j.biopsych.2013.05.001.
   PubMed Web of Science ®Google Scholar
• Liu RT, Walsh RFL, Sheehan AE. Prebiotics and probiotics for depression and anxiety: a systematic review and meta-analysis of controlled clinical trials. Neurosci Biobehav Rev. 2019;102:13–23. doi:10.1016/j.neubiorev.2019.03.023.
   PubMed Web of Science ®Google Scholar
• Smith KS, Greene MW, Babu JR, Frugé AD. Psychobiotics as treatment for anxiety, depression, and related symptoms: a systematic review. Nutr Neurosci. 2021;24:963–77. doi:10.1080/1028415X.2019.1701220.
   PubMed Web of Science ®Google Scholar