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Neurotoxicity Research Volume 4, 2002 - Issue 2
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Original Articles

Preliminary Study of the Behavioral Effects of LBS-neuron Implantation on Seizure Susceptibility Following Middle Cerebral Artery Occlusion in the Rat

Alison E. Willing Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA; Department of Anatomy, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
,
Samuel Saporta Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA; Department of Anatomy, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
,
Jiang Lixian Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
,
Melissa Milliken Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
,
Steve Poulos Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
,
Scott S. Bowersox Layton BioScience, Inc., 709 E Evelyn Ave, Sunnyvale, CA, 94086, USA
&
Paul R. Sanberg Department of Neurosurgery, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA; Department of Pharmacology and Therapeutics, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA; Department of Psychiatry, Center for Aging and Brain Repair, University of South Florida, MDC 78, 12901 Bruce B. Downs Blvd, Tampa, FL, 33612, USA
 show all
Pages 111-118 | Published online: 26 Oct 2010

  • American Heart Association . 2000 . "2001 Heart and Stroke Statistical Update." ” . Dallas, TX : American Heart Association .
  • Asconape , J.J. and Penry , J.K. 1991 . "Poststroke seizures in the elderly" . Clin. Geriatr. Med. , 7 : 483 – 492 .
  • Babb , T.L. , Pertorius , J.K. , Kupfer , W.R. , Mathern , G.W. , Crandall , P.H. and Levesque , M.F. 1992 . "Aberrant synaptic reorganization in human epileptic hippocampus: evidence for feedforward excitation" . Dendron , 1 : 7 – 25 .
  • Baker , K.A. , Hong , M. , Sadi , D. and Mendez , I. 2000 . "Intrastriatal and intranigral grafting of hNT neurons in the 6-OHDA rat model of Parkinson's disease" . Exp. Neurol. , 162 : 350 – 360 .
  • Bertram , E.H. 1997 . "Functional anatomy of spontaneous seizures in a rat model of limbic epilepsy" . Epilepsia , 38 : 95 – 105 .
  • Borlongan , C.V. , Tajima , Y. , Trojanowski , J.Q. , Lee , V.M. and Sanberg , P.R. 1998 . "Cerebral ischemia and CNS transplantation: differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line" . Neuroreport , 9 : 3703 – 3709 .
  • Bragin , A. , Wilson , C.L. and Engel , J. Jr . 2000 . "Chronic epileptogenesis requires development of a network of pathologically interconnected neuron clusters: a hypothesis" . Epilepsia , 41 : S144 – S152 .
  • Chen , L.S. , Wong , J.G. , Banerjee , P.K. and Snead , O.C. 3rd . 1996 . "Kainic acid-induced focal cortical seizure is associated with an increase of synaptophysin immunoreactivity in the cortex" . Exp. Neurol. , 141 : 25 – 31 .
  • Gorelick , P.B. , Sacco , R.L. , Smith , D.B. , Alberts , M. , Mustone-Alexander , L. , Rader , D. , Ross , J.L. , Raps , E. , Ozer , M.N. , Brass , L.M. , Malone , M.E. , Goldberg , S. , Booss , J. , Hanley , D.F. , Toole , J.F. , Greengold , N.L. and Rhew , D.C. 1999 . "Prevention of a first stroke" . JAMA , 281 : 1112 – 1120 .
  • Guillemain , I. , Alonso , G. , Patey , G. , Privat , A. and Chaudieu , I. 2000 . "Human NT2 neurons express a large variety of neurotransmission phenotypes in vitro" . J. Comp. Neurol. , 422 : 380 – 395 .
  • Hartley , R.S. , Margulis , M. , Lee , V.M.-Y. and Tang , C.M. 1999 . "Astrocytes are required for the formation of functional synapses between human NT2N neurons in vitro" . J. Comp. Neurol. , 407 : 1 – 10 .
  • Heuts-van , Raak , L. , Lodder , J. and Kessels , F. 1996 . "Late seizures following a first symptomatic brain infarct are related to large infarcts involving the posterior area around the lateral sucus" . Seizure , 5 : 185 – 194 .
  • Jacobs , K.M. , Hwang , B.J. and Prince , D.A. 1999 . "Focal epileptogenesis in a rat model of polymicrogyria" . J. Neurophysiol. , 81 : 159 – 173 .
  • Jacoby , D.B. , Lindberg , C. , Cunningham , M.G. , Ratliff , J. and Dinsmore , J. 1999 . "Long-term survival of fetal porcine lateral ganglionic eminence cells in the hippocampus of rats" . J. Neurosci. Res. , 56 : 581 – 594 .
  • Johansson , B.B. and Grabowski , M. 1994 . "Functional recovery after brain infarction: plasticity and neural transplantation" . Brain Pathol. , 4 : 85 – 95 .
  • Kilpatrick , C.J. , Davis , S.M. , Tress , B.M. , Rossiter , S.C. , Hopper , J.L. and Vandendriesen , M.L. 1990 . "Epileptic seizures in the acute stroke" . Arch. Neurol. , 47 : 157 – 160 .
  • Koide , K. , Hashitani , T. , Aihara , N. , Mabe , H. and Nishino , H. 1993 . "Improvement of passive avoidance task after grafting of fetal striatal cell suspensions in ischemic striatum in the rat" . Restor. Neurol. Neurosci. , 5 : 205 – 214 .
  • Kokaia , M. , Aebischer , P. , Elmer , E. , Bengzon , J. , Kalen , P. , Kokaia , Z. and Lindvall , O. 1994a . "Seizure suppression in kindling epilepsy by intracerebral implants of GABA--but not by noradrenaline-releasing polymer matrices" . Exp. Brain Res. , 100 : 385 – 394 .
  • Kokaia , M. , Cenci , M.A. , Elmer , E. , Nilsson , O.G. , Kokaia , Z. , Bengzon , J. , Bjorklund , A. and Lindvall , O. 1994b . "Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocampus by superior cervical ganglion or fetal locus coeruleus grafts" . Exp. Neurol. , 130 : 351 – 361 .
  • Kondziolka , D. , Wechsler , L. , Goldstein , S. , Meltzer , C. , Thulborn , K.R. , Gebel , J. , Jannetta , P. , DeCesare , S. , Elder , E.M. , McGrogan , M. , Reitman , M.A. and Bynum , L. 2000 . "Transplantation of cultured human neuronal cells for patients with stroke" . Neurology , 55 : 565 – 569 .
  • Loscher , W. , Ebert , U. , Lehmann , H. , Rosenthal , C. and Nikkhah , G. 1998 . "Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra" . J. Neurosci. Res. , 51 : 196 – 209 .
  • Martinez-Garcia , F.A. , Villaverde , R. , Salmeron , P. , Morales , A. , Molto , J.M. and Fernandez-Barreiro , A. 1998 . "Late onset epileptic crisis and cerebrovascular disease" . Revista de Neurologica , 27 : 671 – 675 .
  • Meierkord , H. , Schuchmann , S. , Buchheim , K. and Heinemann , U. 1997 . "Optical imaging of low Mg 2+ -induced spontaneous epileptiform activity in combined rat entorhinal cortex-hippocampal slices" . Neuroreport , 8 : 1857 – 1861 .
  • Okazaki , M.M. , Evenson , D.A. and Nadler , J.V. 1995 . "Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: visualization after retrograde transport of biocytin" . J. Comp. Neurol. , 352 : 515 – 534 .
  • Oner , P. , Oztas , B. and Kocak , H. 1997 . "Brain cortex Na + -K + ATPase activities in streptozotocin-diabetic and pentylenetetrazol-epileptic rats" . Pharm. Res. , 36 : 69 – 72 .
  • Oner , P. , Kocak , H. and Oztas , B. 2000 . "Effects of streptozotocin-induced diabetes and pentylenetetrazol-induced seizure on brain cortex (Ca 2+) ATPase activity in rats" . Int. J. Neurosci. , 103 : 33 – 40 .
  • Pineau , N. , Charriaut-Marlangue , C. , Motte , J. and Nehlig , A. 1999 . "Pentylenetetrazol seizures induce cell suffering but not death in the immature rat brain" . Dev. Brain Res. , 112 : 139 – 144 .
  • Pleasure , S.J. and Lee , V.M.-Y. 1993 . "NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell" . J. Neurosci. Res. , 35 : 585 – 602 .
  • Pohle , W. , Becker , A. , Grecksch , G. , Juhre , A. and Willenberg , A. 1997 . "Piracetam prevents pentylenetetrazol kindling-induced neuronal loss and learning deficits" . Seizure , 6 : 467 – 474 .
  • Salazar , A.M. , Jabbari , B. , Vance , S.C. , Grafman , J. , Amin , D. and Dillon , J.D. 1985 . "Epilepsy after penetrating head injury. I. Clinical correlates: a report of the Vietnam Head Injury Study" . Neurology , 35 : 1406 – 1414 .
  • Saporta , S. , Borlongan , C.V. and Sanberg , P.R. 1999 . "Neural transplantation of human neuroteratocarcinoma (hNT) neurons into ischemic rats. A quantitative dose-response analysis of cell survival and behavioral recovery" . Neuroscience , 91 : 519 – 525 .
  • Selman , W.R. , VanDerVeer , C. , Whittingham , T.S. , LaManna , J.C. , Lust , W.D. and Ratcheson , R.A. 1987 . "Visually defined zones of focal ischemia in the rat brain" . Neurosurgery , 21 : 825 – 830 .
  • Shetty , A.K. and Turner , D.A. 1997 . "Fetal hippocampal cells grafted to kainate-lesioned CA3 region of adult hippocampus suppress aberrant supragranular sprouting of host mossy fibers" . Exp. Neurol. , 143 : 231 – 245 .
  • Shetty , A.K. , Zaman , V. and Turner , D.A. 2000 . "Pattern of long-distance projections from fetal hippocampal field CA3 and CA1 cell grafts in lesioned CA3 of adult hippocampus follows intrinsic character of respective donor cells" . Neuroscience , 99 : 243 – 255 .
  • Sorensen , J.C. , Grabowski , M. , Zimmer , J. and Johansson , B.B. 1996 . "Fetal neocortical tissue blocks implanted in brain infarcts of adult rats interconnect with the host brain" . Exp. Neurol. , 138 : 227 – 235 .
  • Ying , Z. , Babb , T.L. , Hilbig , A. , Wyllie , E. , Mohamed , A. , Bingaman , W. , Prayson , R. , Staugaitis , S. , Najm , I. and Luders , H.O. 1999 . "Hippocampal chemical anatomy in pediatric and adolescent patients with hippocampal or extrahippocampal epilepsy" . Dev. Neurosci. , 21 : 236 – 247 .
  • Zeller , M. and Strauss , W.L. 1995 . "Retinoic acid induces cholinergic differentiation of NTera2 human embryonal carcinoma cells" . Int. J. Dev. Neurosci. , 13 : 437 – 445 .

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