THE ROLE OF PAH-DNA ADDUCTS IN CAUSING CANCER

REFERENCES

• Brookes , P. and Lawley , P. D. 1964 . Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin: Relation Between Carcinogenic Power of Hydrocarbons and Their Binding to Deoxyribonucleic Acid . Nature , 202 : 781 – 784 .
   PubMed Web of Science ®Google Scholar
• Miller , E. C. and Miller , J. A. 1966 . Mechanisms of Chemical Carcinogenesis: Nature of Proximate Carcinogens and Interactions with Macromolecules . Pharmacological Reviews , 18 : 805 – 838 .
   PubMed Web of Science ®Google Scholar
• Boyland , E. 1950 . The Biological Significance of Metabolism of Polycyclic Compounds . Biochemical Society Symposium , 5 : 40 – 54 .
   Web of Science ®Google Scholar
• Baird , W. M. , Harvey , R. G. and Brookes , P. 1975 . Comparison of the Cellular DNA-Bound Products of Benzo[a]pyrene with the Products Formed by the Reaction of Benzo[a]pyrene 4,5-Oxide with DNA . Cancer Research , 35 : 54 – 57 .
   PubMed Web of Science ®Google Scholar
• Sims , P. , Grover , P. L. , Swaisland , A. , Pal , K. and Hewer , A. 1974 . Metabolic Activity of Benzo[a]pyrene Proceeds by Diol-Epoxide . Nature , 252 : 326 – 328 .
   PubMed Web of Science ®Google Scholar
• Ralston , S. , Law , H. H. S. , Seidel , A. , Albrecht , A. , Luch , A. , Platt , K. L. and Baird , W. M. 1994 . The Potent Carcinogen Dibenzo[a,l]pyrene Is Metabolically Activated to Fjord Region 11,12 Diol 13,14-Epoxides in Human Mammary Carcinoma MCF-7 Cell Culture . Cancer Research , 54 : 887 – 890 .
   PubMed Web of Science ®Google Scholar
• Ralston , S. L. , Coffing , S. L. , Seidel , A. , Luch , A. , Platt , K. L. and Baird , W. M. 1997 . Stereoselective Activation of Dibenzo[a,l]pyrene and Its trans-11,12-Dihydrodiol to Fjord Region 11,12-Diol 13,14 Epoxides in a Human Mammary Carcinoma MCF-7 Cell-Mediated V79 Cell Mutation Assay . Chemical Research in Toxicology , 10 : 687 – 693 .
   PubMed Web of Science ®Google Scholar
• Mahadevan , B. , Dashwood , W.-M. , Luch , A. , Pecaj , A. , Doehmer , J. , Seidel , A. , Periera , C. and Baird , W. M. 2003 . Mutations Induced by (−)anti-11R,25-Dihydrodiol 13S,14R-Epoxide of Dibenzo[a,l]pyrene in the Coding Region of the Hypoxanthine Phosphoribosyl transferase (Hprt) Gene in Chinese Hamster V79 Cells . Environmental and Molecular Mutagenesis , 41 : 131 – 139 .
   PubMed Web of Science ®Google Scholar
• Luch , A. , Coffing , S. L. , Tong , Y. M. , Schneider , A. , Soballa , V. , Greim , H. , Jefcoate , C. R. , Seidel , A. , Greenke , W. F. , Baird , W. M. and Doehmer , J. 1998 . Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[a,l]pyrene . Chemical Research Toxicology , 11 : 686 – 695 .
   PubMed Web of Science ®Google Scholar
• Buters , J. T. M. , Mahadevan , B. , Quintilla-Martinez , L. , Gonzales , F. J. , Greim , H. , Baird , W. M. and Luch , A. 2002 . Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[a,l]pyrene-Induced Tumor Formation . Chemical Research Toxicology , 15 : 1127 – 1135 .
   PubMed Web of Science ®Google Scholar
• Marston , C. P. , Periera , C. , Ferguson , J. , Fischer , K. , Hedstrom , W.-M. , Dashwood and Baird , W. M. 2001 . Effect of a Complex Environmental Mixture from Coal Tar Containing Polycyclic Aromatic Hydrocarbons (PAH) on the Tumor Initiation, PAH-DNA Binding and Metabolic Activation of Carcinogenic PAH in Mouse Epidermis . Carcinogenesis , 22 : 1077 – 1086 . http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11408352 http://www4.infotrieve.com/newmedline/detail.asp?NameID=11408352&Session=&searchQuery=Carcinogenesis%5BJournal+Name%5D+AND+22%5BVolume%5D+AND+1077%5BPage+Number%5D+AND+2001%5BPublication+Date%5D+AND+Dashwood%5BAuthor+Name%5D&count=1
   PubMed Web of Science ®Google Scholar