Determination of Carcinogenic Polycyclic Aromatic Hydrocarbons (PAHs), Aflatoxins, and Nitrosamines in Processed Fish from the Winam Gulf Area of Kenya and Estimated Potential Exposure in Human

REFERENCES

• Lisouza, F.A., P.O. Owuor, and J.O. Lalah. “Variation in Indoor Levels of Polycyclic Aromatic Hydrocarbons from Burning Various Biomass Types in the Traditional Grass-Roofed Households in Western Kenya”. Environmental Poullution 159 (2011): 1810–15.
   PubMed Web of Science ®Google Scholar
• Onyango, A.A., J.O. Lalah, S.O. Wandiga, and J. Gichuki. “Assessment of Polycyclic Aromatic Hydrocarbons in Lates niloticus, Oreochromis niloticus and Rastrineobola argentea as Sources of Human Exposure in Kisumu Bay, Winam Gulf of Lake Victoria.” Bulletin of the Environmental Contamination & Toxicology 88, no. 5 (2012): 747–51.
   PubMed Web of Science ®Google Scholar
• Onyango, A.A., J.O. Lalah, and S.O. Wandiga. “The Effect of Local Cooking Methods on Polycyclic Aromatic Hydrocarbons (PAHs) Contents in Beef, Goat Meat and Pork as Potential Sources of Human Exposure in Kisumu City, Kenya.” Polycyclic Aromatic Compounds 32, no. 5 (2012): 656–68.
   Web of Science ®Google Scholar
• IARC (International Agency for Research of Cancer). “IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.” Supplement 7 (1987); http://monographs.iarc.fr/ENG/Monographs/suppl7.pdf (accessed on December, 12, 2011).
   Google Scholar
• Strzelecki, E.L. “Extraction and Determination of Aspergillus Flavus Metabolites –Aflatoxins from Meat Products. Veterinary Hygiene Research Station Gdansk, Poland,” (2007); http://www.iupac.org/publications/pac/1973/pdf/3503x0297.pdf (accessed on May 10, 2008).
   Google Scholar
• Bommakanti, A.S. and F. Waliyar. “Importance of Aflatoxins in Human and Livestock Health (2002); www.icrisat.org/aflatoxin/health.asp (accessed on May 14, 2011).
   Google Scholar
• IARC (International Agency for Research of Cancer). “Aflatoxins. IARC – Summaries and Evaluations.. 56 (1993): 245; www.inchem.org/documents/iarc/vol56/09-afl.html (accessed on December 12, 2011).
   Google Scholar
• Jakszyn, P. and C.A. Gonzalez. “Nitrosamine and Related Food Intake and Gastric and Oesophageal Cancer Risk: A Systematic Review of the Epidemiological Evidence.” World Journal of Gastroenterology 12, no. 27 (2006): 4296–303.
   PubMed Web of Science ®Google Scholar
• Surhone, L.M., M.T. Timpledon, and S.F. Marseken. Nitrosamine. (Trade paperback, Beta Script Publishing, New Delhi, 2010); books.google.co.ke/books/about/Nitrosamine.html?id=hmXUbwAACAAJ8&redir_esc=y (accessed on October 20, 2010).
   Google Scholar
• Yurchenko, S. and U. Moulders. “Volatile N-nitrosamines in Various Fish Products.” Journal of Food Chemistry 96, no. 2 (2006): 325–33.
   Web of Science ®Google Scholar
• Guillèn, M.D., P. Sopelana, and M.A. Partearroyo. “Food as a Source of PAHs.” Reviews on Environmental Health 12 (1997): 133–46.
   PubMedGoogle Scholar
• Annon, Anonymous. “Polycyclic Aromatic Hydrocarbons in Food.” Toxicological Fact Sheet Series, Issue No. 1, 2009. Food Safety Authority of Ireland; www.fsal.ie/Workarea/DownloadAsset.aspx?=8416 (accessed on August 2, 2011).
   Google Scholar
• Doll, R. “Nature and Nurture: Possibilities for Cancer Control.” Carcinogenesis 17 (1996): 177–84.
   PubMed Web of Science ®Google Scholar
• Panalaks, T. “Determination and Identification of Polycyclic Aromatic Hydrocarbons in Smoked and Charcoal-Broiled Food Products by High Pressure Liquid Chromatography and Gas Chromatography.” Journal of Environmental Science and Health 11, no. 4 (1976): 299–315.
   PubMed Web of Science ®Google Scholar
• Afolabi, A.O., A.E. Adesulu, and L.O. Oke. “Polynuclear Aromatic Hydrocarbons in Some Nigerian Preserved Fresh Water Fish Species.” Journal of Agricultural and Food Chemistry 31, no. 5 (1983): 1083–90.
   PubMed Web of Science ®Google Scholar
• Stegeman, J.J. and J.J. Lech. “Cytochrome P-450 Monooxygenase Systems in Aquatic Species: Carcinogen Metabolism and Biomarkers for Carcinogen and Pollutant Exposure.” Environmental Health Perspectives 90 (1991): 101–9.
   PubMed Web of Science ®Google Scholar
• Kwach, B.O., J.O. Lalah, and S.O. Wandiga. “Spartial and Seasonal Variations in Concentrations of Polycyclic Aromatic Hydrocarbons in Water and Sediment of Kisumu city Bay of Winam Gulf, Lake Victoria-Kenya.” Bulletin of Environmental Contamination and Toxicology 83 (2009): 734–41.
   PubMed Web of Science ®Google Scholar
• Hallet, D.J. and R.W. Brechner. Toxic Contaminants in the Great Lakes. 1^st ed. (New York- Chichestern Brisbane Toronto-Singapore: J. Wiley and Sons, 1984), 213–37.
   Google Scholar
• ATDSR (Agency for Toxic Substances and Disease Registry). “Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs).” (Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 1995); www.atdsdr.cdc.gov/toxprofiles/tp69.pd (accessed on December 9, 2011).
   Google Scholar
• Annon, Anonymous. “Aflatoxins in Food.” (2004); www.wellvet.com/aflatoxins.html. (accessed on October 5, 2011).
   Google Scholar
• IARC (International Agency for Research of Cancer). “IARC Monographs on the evaluation of Carcinogenic Risks to Humans.” Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene. vol. 82 (2002): 171; http://monographs.iarc.fr/ENG/Monographs/vol82/index.php (accessed on December 12, 2011).
   Google Scholar
• Reddy, S.V. and F. Waliyar. “Properties of Aflatoxin and it Producing Fungi.” (2000); www.icrisat.org/aflatoxin/aflatoxin.asp (accessed on May 20, 2010).
   Google Scholar
• Adamson, R.H., P. Correa, S.M. Sieber, K.R. McIntire and D.W. Dalqard. “Carcinogenicity of Aflatoxin B1 in Rhesus Monkeys: Two Additional Cases of Primary Liver Cancer.” Journal of the National Cancer Institute 57, no. 1 (1976): 67–78.
   PubMed Web of Science ®Google Scholar
• Eaton, L.D. Aflatoxin Toxicology. Comprehensive Toxicology. (Pergamon Publications, London, 1997).
   Google Scholar
• Obioha, I.W., A.A. Craft, and M.H. Starh. “Effect of Sodium Nitrate on Aflatoxin Production in Pork Sausages at Different Temperatures and the Effect of Nitrite on Growth of Aspergillus parasiticus in culture.” Journal of Agricultural Food Chemistry 31,no. 5 (1983): 1039–42.
   PubMed Web of Science ®Google Scholar
• Mompoint, J. and L. McGlone. “Aflatoxins in Food and Their Effects on Health.” (2011); http://docs.google.com/viewer?a=v&q=cache:2x8F-K914ugJ:londellmcglone.com/docs/Aflatoxins%2520in%25 (accessed on December 7, 2011).
   Google Scholar
• Pensabene, J.W., J.C. Fagan, W. Fiddler, R.A. Gates, and A.E. Wasserman. “Effect of Frying and Other Cooking Conditions on Nitrosopyrrolidine Formation in Bacon.” Journal of Food Science 39, no. 2 (1974): 314–6.
   Web of Science ®Google Scholar
• Jagannath, R.I., F.W. Miles, T. Panalaks, and P.N. Sen. “A Survey of Fish Products for Volatile N-Nitrosamines.” Journal of the Science of Food and Agriculture 27, no. 6 (1976): 527–30.
   PubMed Web of Science ®Google Scholar
• Nzioka, R.M. “Fish Processing and Distribution in Kenya.” (Mombasa Kenya: KMFRI) Kenya Aqua. (3) (1986): 53–60.
   Google Scholar
• Ogutu, E.M. G. “Fish Handling and Processing in the Artisanal Fisheries of Lake Victoria.” Artisanal Fisheries of Lake Victoria, Kenya. Proceedings of a workshop held in Kisumu, Kenya November 24–26, 1988. (Shirikon Publishers, 1992), 135–139.
   Google Scholar
• Annon, Anonymous. “Smoked Food.” (2008); (accessed on December 4, 2011); www.live-in –green.com/health_info/problematic_food/carcinogenic/smoked.html
   Google Scholar
• Wang, G., S. Lee, M. Lewis, B. Kamath, and R.K. Archer. “Accelerated Solvent Extraction and GC/MS for Determination of Polycyclic Aromatic Hydrocarbons in Smoked Fish Samples.” Journal of Agricultural and Food Chemistry 47, no. 3 (1999): 1062–6.
   PubMed Web of Science ®Google Scholar
• William, H. and W.L. George. “Natural Toxins,” in Official Methods of Analysis of AOAC International, 18th ed. (Gaithersburg, MD: AOAC Publishers, 2005), Ch., 21–22.
   Google Scholar
• Fine, D.H., D.P. Rounbehler, and P.E. Oettinger. “A Rapid Method for the Determination of Sub-part per Billion Amounts of N-nitroso Compounds in Foodstuffs.” Analytica Chimica Acta 78 (1975): 383–9.
   PubMed Web of Science ®Google Scholar
• Alley, E.R. “Appendix A to Part 136 Methods for Organic Chemical Analysis of Municipal and Industrial Wastewater,” Method 607- Nitrosamines, in Water Quality Control Handbook (McGraw Hill Professional, London, 2000).
   Google Scholar
• USEPA (United States Environmental Protection Agency). “Nitrogen, Nitrate-Nitrite. Method 353.2,” in Methods for Chemicals Analysis of Water and Wastes. (Cincinnati, Ohio: U. S. Environmental Protection Agency, 1983), 353-2.1—353-2.5.
   Google Scholar
• Kahl, H. and M. Leinemman. “Determination of Polycyclic Aromatic Hydrocarbons in Smoked Fishery Products from Different Smoking Kilns.” Z. Lebensm Unters Forsch 202, no. 6 (1996): 458–64.
   PubMedGoogle Scholar
• Akpambang, V.O., G. Purcaro, L. Lajide, I.A. Amoo, L.S. Conte, and S. Moret. “Determination of Polycyclic Aromatic Hydrocarbons in Commonly Consumed Nigerian Smoked/Grilled Fish and Meat.” Food Additives and Contaminants. Part A, Chemistry, Analysis Control, Exposure, and Risk Assessment 29, no. 7 (2009): 1096–1103.
   Google Scholar
• Stolyhwo, A. and Z.E. Sikorski. “Polycyclic Aromatic Hydrocarbons in Smoked Fish”. Food Chem. 91 (2) (2005): 303–311.
   Web of Science ®Google Scholar
• FAO (Food and Agriculture Organization of the United Nation). Report of the Preparatory Assistance Mission (for the Kenya Lake Victoria Basin Fisheries Development). Fisheries Development Programme in the Lake Basin region, Kenya. (FAO Corporate Document Repository, 1982); http://www.fao.org/docrep/field/003/P8766E/P8766E03.html (accessed on November 15, 2011).
   Google Scholar
• Bukola, C.A., A.O. Abiodun, and G.P. Ukpe. “Mycofloral of Smoke Dried Fishes Sold in Uyo Eastern Nigeria.” World Journal of Agricultural Sciences 4, no. 3 (2008): 346–50.
   Google Scholar
• FDA (United States Food and Drug Administration). “Guidance for Industry: Action Levels for Poisonous or Deleterious Substances in Human Food and Animal Feed.” (2000); www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocument/ChemicalContaminantsandPesticides/uci (accessed on October 2, 2011).
   Google Scholar
• FSA (Food Standard Agency). “Survey of Spices for Aflatoxins and Ochratoxin A.” (2005); www.food.gov.uk/science/surveillance/fsis2005/fsis7305 (accessed on October 20, 2011).
   Google Scholar
• Banadda, N. “Characterization of Non Point Sources Pollutants and Their Dispersion in Lake Victoria: A Case Study of Goba Landing Site in Uganda.” African Journal of Environmental Science & Technology 5, no. 2 (2011): 73–9; www.ajol.info/index.php/ajest/article/view/71909/60867 (accessed on December 18, 2011).
   Google Scholar
• Lawrence, F.J. and F.D. Weber. “Determination of Polycyclic Aromatic Hydrocarbons in Some Canadian Commercial Fish, Shell Fish and Meat Products by Liquid Chromatography with Confirmation by Capillary Gas Chromatography- Mass Spectrometry.” Journal of Agricultural Food Chemistry 32, no. 4 (1984): 789–94.
   Web of Science ®Google Scholar
• Orony, D.N. A. “Polycyclic aromatic hydrocarbons, nitrosamines and aflatoxins in fish from Winam Gulf L. Victoria.” MSc thesis, Maseno University, Kenya (2012).
   Google Scholar