188
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Synthesized Phytomolecular Hybrids as Natural Interventions to Manage Hyperlipidemia and to Ameliorate Diabetes in Streptozotocin Induced Mice

, , , , , , , ORCID Icon, , , , , & show all
Pages 6136-6154 | Received 31 Mar 2021, Accepted 27 Aug 2021, Published online: 12 Oct 2021

References

  • V. Kumar, D. Ahmed, P. S. Gupta, F. Anwar, and M. Mujeeb, “Anti-Diabetic, anti-Oxidant and anti-Hyperlipidemic Activities of Melastoma Malabathricum Linn. leaves in Streptozotocin Induced Diabetic Rats,” BMC Complementary and Alternative Medicine 13, (2013): 222.
  • E. Apostolidis, Y.-I. Kwon, and K. Shetty, “Inhibitory Potential of Herb, Fruit, and Fungal-Enriched Cheese against Key Enzymes Linked to Type 2 Diabetes and Hypertension,” Innovative Food Science & Emerging Technologies 8, no. 1 (2007): 46–54.
  • C. J. Bailey, and C. Day, “Traditional Plant Medicines as Treatments for Diabetes,” Diabetes Care 12, no. 8 (1989): 553–64.
  • S. K. Swanston-Flatt, C. Day, C. J. Bailey, and P. R. Flatt, “Traditional Plant Treatments for Diabetes. Studies in Normal and Streptozotocin Diabetic Mice,” Diabetologia 33, no. 8 (1990): 462–4.
  • T. J. Wang, M. G. Larson, R. S. Vasan, S. Cheng, E. P. Rhee, E. McCabe, G. D. Lewis, C. S. Fox, P. F. Jacques, C. Fernandez, et al. “Metabolite Profiles and the Risk of Developing Diabetes,” Nature Medicine 17, no. 4 (2011): 448–53.
  • S. L. Abbate, and J. D. Brunzell, “Pathophysiology of Hyperlipidemia in Diabetes Mellitus,” Journal of Cardiovascular Pharmacology 16 Suppl 9 (1990): S1–S7.
  • T. O'Brien, T. T. Nguyen, and B. R. Zimmerman, “Hyperlipidemia and Diabetes Mellitus,” Mayo Clinic Proceedings 73, no. 10 (1998): 969–76.
  • C. M. O. Volpe, P. H. Villar-Delfino, P. M. F. Dos Anjos, and J. A. Nogueira-Machado, “Cellular Death, Reactive Oxygen Species (ROS) and Diabetic Complications,” Cell Death & Disease 9, no. 2 (2018): 119.
  • M. Umashanker, and S. Shruti, “Traditional Indian Herbal Medicine Used as Antipyretic, Antiulcer, anti-Diabetic and Anticancer: A Review,” IJRPC 1, no. 4 (2011): 1152–1159.
  • S. Radhika, K. H. Smila, and R. Muthezhilan, “Antidiabetic and Hypolipidemic Activity of Punica Granatum Linn on Alloxan Induced Rats,” World Journal of Medical Sciences 6, no. 4 (2011): 178–182.
  • A. D. Harries, S. Satyanarayana, A. M. V. Kumar, S. B. Nagaraja, P. Isaakidis, S. Malhotra, S. Achanta, B. Naik, N. Wilson, R. Zachariah, et al. “Epidemiology and Interaction of Diabetes Mellitus and Tuberculosis and Challenges for Care: A Review,” Public Health Action 3, no. Suppl 1 (2013): S3–S9.,
  • N. H. A. El-Soud, M. Y. Khalil, J. S. Hussein, F. S. H. Oraby, and A. R. H. Farrag, “Antidiabetic Effects of Fenugreek Alkaliod Extract in Streptozotocin Induced Hyperglycemic Rats,” Journal of Applied Sciences Research 3, no. 10 (2007): 1073–1083.
  • J. Dwivedi, A. Gupta, S. Verma, M. Dwivedi, S. Paliwal, and A. K. S. Rawat, “Validated High-Performance Thin-Layer Chromatographic Analysis of Ursolic Acid and β-Sitosterol in the Methanolic Fraction of Paederia foetida L. Leaves,” JPC - Journal of Planar Chromatography - Modern TLC 31, no. 5 (2018): 377–381.
  • R. J. Marles, and N. R. Farnsworth, “Antidiabetic Plants and Their Active Constituents,” Phytomedicine 2, no. 2 (1995): 137–189.
  • J. Dwivedi, A. Gupta, S. Verma, S. Paliwal, and A. K. S. Rawat, “Validated Simultaneous High-Performance Thin-Layer Chromatographic Analysis of Ursolic Acid, β-Sitosterol, Lupeol and Quercetin in the Methanolic Fraction of Ichnocarpus Frutescens,” JPC - Journal of Planar Chromatography - Modern TLC 32, no. 2 (2019): 103–108.
  • M. Modak, P. Dixit, J. Londhe, S. Ghaskadbi, and T. P. A. Devasagayam, “Recent Advances in Indian Herbal Drug Research Guest Editor: Thomas Paul Asir Devasagayam Indian Herbs and Herbal Drugs Used for the Treatment of Diabetes,” Journal of Clinical Biochemistry and Nutrition 40, no. 3 (2007): 163–173.
  • B. Punit, P. Paul, J. Mudgal, P. G. Nayak, S. T. Pannakal, K. I. Priyadarsini, and M. K. Unnikrishnan, “Antidiabetic, Antihyperlipidemic and Antioxidant Effects of the Flavonoid Rich Fraction of Pilea Microphylla (L.) in High Fat Diet/Streptozotocin-Induced Diabetes in Mice,” Experimental and Toxicologic Pathology 64, no. 6 (2012): 651–658.
  • A. B. Deore, V. D. Sapakal, and N. S. Naikwade, “Role of Oxidative Stress in Pathogenesis of Diabetes and Its Complications,” Pharmacologyonline 2, (2011): 603–621.
  • J. W. Baynes, and S. R. Thorpe, “Role of Oxidative Stress in Diabetic Complications: A New Perspective on an Old Paradigm,” Diabetes 48, no. 1 (1999): 1–9.
  • K. Lorig, P. L. Ritter, D. D. Laurent, K. Plant, M. Green, V. B. B. Jernigan, and S. Case, “Online Diabetes Self-Management Program: A Randomized Study,” Diabetes Care 33, no. 6 (2010): 1275–1281.
  • N. Payghami, S. Jamili, A. Rustaiyan, S. Saeidnia, M. Nikan, and A. R. Gohari, “Alpha-Amylase Inhibitory Activity and Sterol Composition of the Marine Algae, Sargassum Glaucescens,” Pharmacognosy Research 7, no. 4 (2014): 314–321.
  • H. Varinli, M. J. Osmond-McLeod, P. L. Molloy, and P. Vallotton, “LipiD-QuanT: A Novel Method to Quantify Lipid Accumulation in Live Cells,” Journal of Lipid Research 56, no. 11 (2015): 2206–2216.
  • M. Sharma, S. Sharma, V. Sharma, K. Sharma, S. K. Yadav, P. Dwivedi, S. Agrawal, S. K. Paliwal, A. K. Dwivedi, J. P. Maikhuri, et al. “Oleanolic-Bioenhancer Coloaded Chitosan Modified Nanocarriers Attenuate Breast Cancer Cells by Multimode Mechanism and Preserve Female Fertility,” International Journal of Biological Macromolecules 104, no. Pt A (2017): 1345–1358.
  • K. Shanker, J. Naradala, G. K. Mohan, G. S. Kumar, and P. L. Pravallika, “A Sub-Acute Oral Toxicity Analysis and Comparative in Vivo anti-Diabetic Activity of Zinc Oxide, Cerium Oxide, Silver Nanoparticles, and Momordica Charantia in Streptozotocin-Induced Diabetic Wistar Rats,” RSC Advances 7, no. 59 (2017): 37158–37167.
  • J. E. Emordi, E. O. Agbaje, I. A. Oreagba, and O. I. Iribhogbe, “Antidiabetic and Hypolipidemic Activities of Hydroethanolic Root Extract of Uvaria Chamae in Streptozotocin Induced Diabetic Albino Rats,” BMC Complementary and Alternative Medicine 16, no. 1 (2016): 468–468.
  • S. Ghosh, M. Ahire, S. Patil, A. Jabgunde, M. B. Dusane, B. N. Joshi, K. Pardesi, S. Jachak, D. D. Dhavale, and B. A. Chopade, “Antidiabetic Activity of Gnidia Glauca and Dioscorea Bulbifera: Potent Amylase and Glucosidase Inhibitors,” Evidence-Based Complementary and Alternative Medicine 2012, (2012): 1–10.
  • D. K. Patel, S. K. Prasad, R. Kumar, and S. Hemalatha, “An Overview on Antidiabetic Medicinal Plants Having Insulin Mimetic Property,” Asian Pacific Journal of Tropical Biomedicine 2, no. 4 (2012): 320–330.
  • G. Berube, “An Overview of Molecular Hybrids in Drug Discovery,” Expert Opin Drug Discov 11, no. 3 (2016): 281–305.
  • W. R. Rowley, C. Bezold, Y. Arikan, E. Byrne, and S. Krohe, “Diabetes 2030: Insights from Yesterday, Today, and Future Trends,” Population Health Management 20, no. 1 (2017): 6–12.
  • Z. Wang, J. Wang, and P. Chan, “Treating Type 2 Diabetes Mellitus with Traditional Chinese and Indian Medicinal Herbs,” Evidence-Based Complementary and Alternative Medicine : eCAM 2013 (2013): 343594.
  • R. P. Nankar, and M. Doble, “Hybrid Drug Combination: Anti-Diabetic Treatment of Type 2 Diabetic Wistar Rats with Combination of Ellagic Acid and Pioglitazone,” Phytomedicine 37, (2017): 4–9.
  • S. Rajan, S. Puri, D. Kumar, M. H. Babu, K. Shankar, S. Varshney, A. Srivastava, A. Gupta, M. S. Reddy, and A. N. Gaikwad, “Novel Indole and Triazole Based Hybrid Molecules Exhibit Potent anti-Adipogenic and Antidyslipidemic Activity by Activating Wnt3a/Beta-Catenin Pathway,” European Journal of Medicinal Chemistry 143, (2018): 1345–1360.
  • M. Sharma, R. Malik, A. Verma, P. Dwivedi, G. S. Banoth, N. Pandey, J. Sarkar, P. R. Mishra, and A. K. Dwivedi, “Folic Acid Conjugated Guar Gum Nanoparticles for Targeting Methotrexate to Colon Cancer,” Journal of Biomedical Nanotechnology 9, no. 1 (2013): 96–106.
  • S. K. Bharti, S. Krishnan, A. Kumar, and A. Kumar, “Antidiabetic Phytoconstituents and Their Mode of Action on Metabolic Pathways,” Therapeutic Advances in Endocrinology and Metabolism 9, no. 3 (2018): 81–100.
  • R. Colas, V. Pruneta-Deloche, M. Guichardant, C. Luquain-Costaz, C. Cugnet-Anceau, M. Moret, H. Vidal, P. Moulin, M. Lagarde, and C. Calzada, “Increased Lipid Peroxidation in LDL from Type-2 Diabetic Patients,” Lipids 45, no. 8 (2010): 723–731.
  • R. Giri, M. M. Kesavulu, B. K. Rao, V. Ramana, and C. A. Rao, “Hyperlipidemia, Increased Lipid Peroxidation and Changes in Antioxidant Enzymes, Na(+)-K(+)-ATPase in Erythrocytes of Type 2 Diabetic Patients in Andhra Pradesh,” Indian Journal of Clinical Biochemistry 14, no. 2 (1999): 168–175.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.