Synthesis, Biological Evaluation, and in-Silico Molecular Docking Studies of Multifunctional Thiazolidine Derivatives

References

• F.M.E. Wagenlehner, and F. Dittmar, “Global Burden of Bacterial Antimicrobial Resistance in 2019: A Systematic Analysis,” European Urology 82, no. 6 (2022): 658. doi:10.1016/j.eururo.2022.08.023
   PubMedGoogle Scholar
• M.E.A. de Kraker, A.J. Stewardson, and S. Harbarth, “Will 10 Million People Die a Year Due to Antimicrobial Resistance by 2050?,” PLOS Medicine 13, no. 11 (2016): e1002184. doi:10.1371/journal.pmed.1002184
   PubMed Web of Science ®Google Scholar
• N.T. Hillock, T.L. Merlin, J. Turnidge, and J. Karnon, “Modelling the Future Clinical and Economic Burden of Antimicrobial Resistance: The Feasibility and Value of Models to Inform Policy,” Applied Health Economics and Health Policy 20, no. 4 (2022): 479–486. doi:10.1007/s40258-022-00728-x
   PubMed Web of Science ®Google Scholar
• CDC. “Antibiotic Resistance Threats in the United States”. 2019. https://www.cdc.gov/drugresistance/biggest-threats.html (accessed December 24, 2022).
   Google Scholar
• R.J. Fair, and Y. Tor, “Antibiotics and Bacterial Resistance in the 21st Century,” Perspectives in Medicinal Chemistry 6 (2014): PMC.S14459. doi:10.4137/PMC.S14459
   Google Scholar
• J.A. Bengoechea, and C.G.G. Bamford, “SARS-CoV-2, Bacterial co-Infections, and AMR: The Deadly Trio in COVID-19?,” EMBO Molecular Medicine 12, no. 7 (2020): e12560. doi:10.15252/emmm.202012560
   PubMed Web of Science ®Google Scholar
• S. Arikan-Akdagli, M. Ghannoum, and J.F. Meis, “Antifungal Resistance: Specific Focus on Multidrug Resistance in Candida auris and Secondary Azole Resistance in Aspergillus fumigatus,” Journal of Fungi 4, no. 4 (2018): 129. doi:10.3390/jof4040129
   Web of Science ®Google Scholar
• Z. Rankovic, and R. Morphy, Lead Generation Approaches in Drug Discovery (New York: John Wiley & Sons, 2010).
   Google Scholar
• A. C. Anderson, “structure-Based Functional Design of Drugs: From Target to Lead Compound,” Methods in Molecular Biology 823 (2012): 359–366. doi:10.1007/978-1-60327-216-2_23
   PubMedGoogle Scholar
• L. Costantino, and D. Barlocco, “Privileged Structures as Leads in Medicinal Chemistry,” Current Medicinal Chemistry 13, no. 1 (2006): 65–85. doi:10.2174/092986706775197999
   PubMed Web of Science ®Google Scholar
• A. Verma, and S. K. Saraf, “4-Thiazolidinone–a Biologically Active Scaffold,” European Journal of Medicinal Chemistry 43, no. 5 (2008): 897–905. doi:10.1016/j.ejmech.2007.07.017
   PubMed Web of Science ®Google Scholar
• M.R. Bockman, C.A. Engelhart, J.D. Cramer, M.D. Howe, N.K. Mishra, M. Zimmerman, P. Larson, N. Alvarez-Cabrera, S.W. Park, H.I.M. Boshoff, et al. “Investigation of (S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase,” ACS Infectious Diseases 5, no. 4 (2019): 598–617. doi:10.1021/acsinfecdis.8b00345
   PubMed Web of Science ®Google Scholar
• X. Ye, W. Zhou, Y. Li, Y. Sun, Y. Zhang, H. Ji, and Y. Lai, “Darbufelone, a Novel anti-Inflammatory Drug, Induces Growth Inhibition of Lung Cancer Cells Both in Vitro and in Vivo,” Cancer Chemotherapy and Pharmacology 66, no. 2 (2010): 277–285. doi:10.1007/s00280-009-1161-z
   PubMed Web of Science ®Google Scholar
• W. Löscher, A. von Hodenberg, B. Nolting, C.P. Fassbender, and C. Taylor, “Ralitoline: A Reevaluation of Anticonvulsant Profile and Determination of “Active” Plasma Concentrations in Comparison with Prototype Antiepileptic Drugs in Mice,” Epilepsia 32, no. 4 (1991): 560–568. doi:10.1111/j.1528-1157.1991.tb04693.x
   PubMed Web of Science ®Google Scholar
• J. Greven, and O. Heidenreich, “Effects of Ozolinone, a Diuretic Active Metabolite of Etozoline, on Renal Function,” Naunyn-Schmiedeberg’s Archives of Pharmacology 304, no. 3 (1978): 283–287. doi:10.1007/BF00507970
   PubMed Web of Science ®Google Scholar
• Y.N. Mabkhot, A. Alsayari, A. Bin Muhsinah, H. Algarni, S.M. Soliman, N.A. Kheder, H.A. Ghabbour, Y.I. Asiri, M.H. Mahnash, S.Tasqeeruddin, et al. “Synthesis, X-Ray Structural Analysis and Computational Studies of a Novel Bis(2-Thienyl)Disulfide Derivative,” Polycyclic Aromatic Compounds 42, no. 5 (2022): 2852–2860. doi:10.1080/10406638.2020.1852281
   Web of Science ®Google Scholar
• M. Amir, S.A. Javed, and M.Z. Hassan, “Synthesis and Antimicrobial Activity of Pyrazolinone and Pyrazole Analogues Containing Quinoline Moiety,” Indian Journal of Chemistry 52B, no. 12 (2013): 1493–1499. http://nopr.niscpr.res.in/handle/123456789/24770.
   Google Scholar
• M.F. Farhat, A.M.M. El-Saghier, M.A. Makhlouf, K.M. Kreddan, and A.B. Elmezoughi, “Ketene N,S-Acetals in Heterocyclic Synthesis: Part 1: Synthesis of N-Phenyl-2-Ylidene and 2,5-Diylidene-4-Thiazolidinone Derivatives,” Journal of Sulfur Chemistry 28, no. 6 (2007): 563–572. doi:10.1080/17415990701586823.
   Google Scholar
• P. Wayne, Clinical and Laboratory Standards Institute: Performance Standards for Antimicrobial Susceptibility Testing (Wayne, PA: ASM Press, 2011).
   Google Scholar
• T. Mosmann, “Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assays,” Journal of Immunological Methods 65, no. 1–2 (1983): 55–63. doi:10.1016/0022-1759(83)90303-4
   PubMed Web of Science ®Google Scholar
• OpenEye VIDA. version 4.1.2; OpenEye Scientific Software, Santa Fe, NM (USA). 2020. http://www.eyesopen.com.
   Google Scholar
• OpenEye Database Preparation. Filter. 2020. https://www.eyesopen.com/filter.
   Google Scholar
• OpenEye Scientific Software. “OpenEye Applications 2020.2”. 2023. https://docs.eyesopen.com/applications (Accessed on 25 December 2020).
   Google Scholar
• OpenEye Scientific Software. OpeEye Fast Rigid Exhaustive Docking (FRED) Receptor, version 2.2.5. 2020. http://www.eyesopen.com.
   Google Scholar
• CBDD Group. ADMETLAB2.0. 2020. https://admetmesh.scbdd.com/ (accessed November 6, 2021).
   Google Scholar
• G. Xiong, Z. Wu, J. Yi, L. Fu, Z. Yang, C. Hsieh, M. Yin, X. Zeng, C. Wu, A. Lu, et al. “ADMETlab 2.0: An Integrated Online Platform for Accurate and Comprehensive Predictions of ADMET Properties,” Nucleic Acids Research 49 (2021): W5–W14. doi:10.1093/nar/gkab255
   PubMed Web of Science ®Google Scholar
• OpenEye. OEDocking 4.2.1.0. 2023. https://docs.eyesopen.com/applications/oedocking/index.html (accessed October 11, 2021).
   Google Scholar
• OpenEye. Omega 4.2.2.0. 2023. https://docs.eyesopen.com/applications/omega/index.html (accessed October 11, 2021).
   Google Scholar
• OpenEye. Chemgauss4. 2023. https://docs.eyesopen.com/applications/oedocking/theory/hybrid_theory.html#chemgauss4 (accessed November 6, 2021).
   Google Scholar
• OpenEye. DockingReport. 2023. https://docs.eyesopen.com/applications/oedocking/DockingReport.html#docking-report (accessed November 6, 2021).
   Google Scholar