Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

References

• Agência Nacional de Vigilancia Sanitária. Dispõe sobre os requisitos mínimos para a validac¸ ão de métodos bioanalíticos empregados emestudos com fins de registro e pós-registro de medicamentos; RDC 27; Agência Nacional de Vigilancia Sanitária: Brasilia, Brazil, 2012.
   Google Scholar
• Agilent Technologies. Control pH during Method Development for Better Chromatography; Agilent Technologies: Santa Clara, CA, 2012. http://www.chem.agilent.com/Library/technicaloverviews/Public/5990-9984EN.pdf
   Google Scholar
• Ahn, K. C.; Lohstroh, P.; Gee, S. J.; Gee, N. A.; Lasley, B.; Hammock, B. D. High-Throughput Automated Luminescent Magnetic Particle-Based Immunoassay to Monitor Human Exposure to Pyrethroid Insecticides. Anal. Chem. 2007, 79(23), 8883–8890.
   PubMed Web of Science ®Google Scholar
• Ajmani, R. S.; Rifkind, J. M. Hemorheological Changes during Human Aging. Gerontology 1998, 44(2), 111–120.
   PubMed Web of Science ®Google Scholar
• Antignac, J.-P.; de Wasch, K.; Monteau, F.; De Brabander, H.; Andre, F.; Le Bizec, B. The Ion Suppression Phenomenon in Liquid Chromatography-Mass Spectrometry and Its Consequences in the Field of Residue Analysis. Anal. Chim. Acta 2005, 529(1–2), 129–136.
   Web of Science ®Google Scholar
• Baker, S. E.; Olsson, A. O.; Needham, L. A.; Barr, D. B. High-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantifying Sulfonylurea Herbicides in Human Urine: Reconsidering the Validation Process. Anal. Bioanal. Chem. 2005, 383(6), 963–976.
   PubMed Web of Science ®Google Scholar
• Berg, T.; Strand, D. H. 13C Labelled Internal Standards—A Solution to Minimize Ion Suppression Effects in Liquid Chromatography-Tandem Mass Spectrometry Analyses of Drugs in Biological Samples? J. Chromatogr. A 2011, 1218(52), 9366–9374.
   PubMed Web of Science ®Google Scholar
• Bonfiglio, R.; King, R. C.; Olah, T. V.; Merkle, K. The Effects of Sample Preparation Methods on the Variability of the Electrospray Ionization Response for Model Drug Compounds. Rapid Commun. Mass Spectrom. 1999, 13(12), 1175–1185.
   PubMed Web of Science ®Google Scholar
• Briscoe, C. J.; Stiles, M. R.; Hage, D. S. System Suitability in Bioanalytical LC/MS/MS. J. Pharm. Biomed. Anal. 2007, 44(2), 484–491.
   PubMed Web of Science ®Google Scholar
• Cappiello, A.; Famiglini, G.; Palma, P.; Pierini, E.; Termopoli, V.; Trufelli, H. Overcoming Matrix Effects in Liquid Chromatography-Mass Spectrometry. Anal. Chem. 2008, 80(23), 9343–9348.
   PubMed Web of Science ®Google Scholar
• Chambers, E.; Wagrowski-Diehl, D. M.; Lu, Z.; Mazzeo, J. R. Systematic and Comprehensive Strategy for Reducing Matrix Effects in LC/MS/MS Analyses. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2007, 852(1–2), 22–34.
   PubMed Web of Science ®Google Scholar
• Chiu, M. L.; Lawi, W.; Snyder, S. T.; Wong, P. K.; Liao, J. C.; Gau, V. Matrix Effects—A Challenge Toward Automation of Molecular Analysis. JALA 2010, 15(3), 233–242.
   Web of Science ®Google Scholar
• Colby, B. N.; McCaman, M. W. A Comparison of Calculation Procedures for Isotope Dilution Determinations Using Gas Chromatography Mass Spectrometry. Biomed. Mass Spectrom. 1979, 6(6), 225–230.
   PubMedGoogle Scholar
• Dams, R.; Huestis, M. A.; Lambert, W. E.; Murphy, C. M. Matrix Effect in Bio-analysis of Illicit Drugs with LC-MS/MS: Influence of Ionization Type, Sample Preparation, and Biofluid. J. Am. Soc. Mass Spectrom. 2003, 14(11), 1290–1294.
   PubMed Web of Science ®Google Scholar
• Dewé, W.; De Smet, M.; Evrard, N.; Culot, B.; Lestelle, M.; Saucez, G.; Ingels, D.; Taillieu, X. Partial Within-Animal Calibration: A New Calibration Approach in Lead Optimisation High-Throughput Bioanalysis. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2007, 854(1–2), 183–191.
   PubMed Web of Science ®Google Scholar
• Erney, D. R.; Gillespie, A. M.; Gilvydis, D. M.; Poole, C. F. Explanation of the Matrix-Induced Chromatographic Response Enhancement of Organophosphorus Pesticides during Open-Tubular Column Gas-Chromatography with Splitless or Hot On-Column Injection and Flame Photometric Detection. J. Chromatogr. A 1993, 638(1), 57–63.
   Web of Science ®Google Scholar
• European Medicines Agency. Guideline on Bioanalytical Method Validation; EMA: London, 2011. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf
   Google Scholar
• Furey, A.; Moriarty, M.; Bane, V.; Kinsella, B.; Lehane, M. Ion Suppression; A Critical Review on Causes, Evaluation, Prevention and Applications. Talanta 2013, 115, 104–122.
   PubMed Web of Science ®Google Scholar
• Garcia, M. C. The Effect of the Mobile Phase Additives on Sensitivity in the Analysis of Peptides and Proteins by High-Performance Liquid Chromatography-Electrospray Mass Spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2005, 825(2), 111–123.
   PubMed Web of Science ®Google Scholar
• Garrido Frenich, A.; Martínez Vidal, J. L.; Fernández Moreno, J. L.; Romero-González, R. Compensation for Matrix Effects in Gas Chromatography-Tandem Mass Spectrometry Using a Single Point Standard Addition. J. Chromatogr. A 2009, 1216(23), 4798–4808.
   PubMed Web of Science ®Google Scholar
• Ghosh, C.; Shinde, C. P.; Chakraborty, B. S. Ionization Polarity as a Cause of Matrix Effects, Its Removal and Estimation in ESI-LC-MS/MS Bio-analysis. J. Anal. Bioanal. Tech. 2010, 1, 106.
   Google Scholar
• Ghosh, C.; Shinde, C. P.; Chakraborty, B. S. Influence of Ionization Source Design on Matrix Effects during LC-ESI-MS/MS Analysis. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2012, 893, 193–200.
   PubMed Web of Science ®Google Scholar
• Gonzalez, O.; Blanco, M. E.; Iriarte, G.; Bartolomé, L.; Maqurequi, M. I.; Alonso, R. M. Bioanalytical Chromatographic Method Validation According to Current Regulations, with a Special Focus on the Non-well Defined Parameters Limit of Quantification, Robustness and Matrix Effect. J. Chromatogr. A 2014, 1353, 10–27.
   PubMed Web of Science ®Google Scholar
• Hajslova, J.; Zrostlikova, J. Matrix Effects in (Ultra)trace Analysis of Pesticide Residues in Food and Biotic Matrices. J. Chromatogr. A 2003, 1000(1–2), 181–197.
   PubMed Web of Science ®Google Scholar
• Hewavitharana, A. K. Matrix Matching in Liquid Chromatography-Mass Spectrometry with Stable Isotope Labelled Internal Standards—Is It Necessary? J. Chromatogr. A 2011, 1218(2), 359–361.
   PubMed Web of Science ®Google Scholar
• Holcapek, M.; Volná, K; Jandera, P.; Kolárová, L.; Lemr, K.; Exner, M.; Církva, A. Effects of Ion-Pairing Reagents on the Electrospray Signal Suppression of Sulphonated Dyes and Intermediates. J. Mass Spectrom. 2004, 39(1), 43–50.
   PubMed Web of Science ®Google Scholar
• Ismaiel, O. A.; Zhang, T. Y.; Jenkins, R. G.; Karnes, H. T. Investigation of Endogenous Blood Plasma Phospholipids, Cholesterol and Glycerides That Contribute to Matrix Effects in Bioanalysis by Liquid Chromatography/Mass Spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2010, 878(31), 3303–3316.
   PubMed Web of Science ®Google Scholar
• Jewett, B. N.; Ramaley, L.; Kwak, J. C. T. Atmospheric Pressure Ionization Mass Spectrometry Techniques for the Analysis of Alkyl Ethoxysulfate Mixtures. J. Am. Soc. Mass Spectrom. 1999, 10(6), 529–536.
   Web of Science ®Google Scholar
• King, R.; Bonfiglio, R.; Fernandez-Metzler, C.; Miller-Stein, C.; Olah, T. Mechanistic Investigation of Ionization Suppression in Electrospray Ionization. J. Am. Soc. Mass Spectrom. 2000, 11(11), 942–950.
   PubMed Web of Science ®Google Scholar
• Le Grand, R.; Dulaurent, S.; Gaulier, J. M.; Saint-Marcoux, F.; Moesch, C.; Lachâtre, G. Simultaneous Determination of Five Synthetic Pyrethroid Metabolites in Urine by Liquid Chromatography-Tandem Mass Spectrometry: Application to 39 Persons without Known Exposure to Pyrethroids. Toxicol. Lett. 2012, 210(2), 248–253.
   PubMed Web of Science ®Google Scholar
• Little, J. L.; Wempe, M. F.; Buchanan, C. M. Liquid Chromatography-Mass Spectrometry/Mass Spectrometry Method Development for Drug Metabolism Studies: Examining Lipid Matrix Ionization Effects in Plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2006, 833(2), 219–230.
   PubMed Web of Science ®Google Scholar
• Matuszewski, B. K.; Constanzer, M. L.; Chavez-Eng, C. M. Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC-MS/MS. Anal. Chem. 2003, 75(13), 3019–3030.
   PubMed Web of Science ®Google Scholar
• Mei, H.; Hsieh, Y. S.; Nardo, C.; Xu, X.; Wang, S.; Ng, K; Korfmacher, W. A. Investigation of Matrix Effects in Bioanalytical High-Performance Liquid Chromatography/Tandem Mass Spectrometric Assays: Application to Drug Discovery. Rapid Commun. Mass Spectrom. 2003, 17(1), 97–103.
   PubMed Web of Science ®Google Scholar
• Ministry of Health, Labour and Welfare. Guideline on Bioanalytical Method Validation in Pharmaceutical Development; Ministry of Health, Labour and Welfare: Tokyo, Japan, 2013.
   Google Scholar
• Montesano, M. A.; Olsson, A. O.; Kuklenyik, P.; Needham, L. L.; Bradman, A. S.; Barr, B. D. Method for Determination of Acephate, Methamidophos, Omethoate, Dimethoate, Ethylenethiourea and Propylenethiourea in Human Urine Using High-Performance Liquid Chromatography-Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry. J. Expo. Sci. Environ. Epidemiol. 2007, 17(4), 321–330.
   PubMed Web of Science ®Google Scholar
• Nishioka, M.; Mccauley, M.; Andrews, K; Lukuch, C.; Wilkins, J., III; Fortmann, R. Development, Validation, and Field Use of a Novel Method for Extracting and Analyzing Organophosphate (OP) and Pyrethroid Pesticide Metabolites and Creatinine from Commercial Disposable Diapers. Epidemiology 2006, 17(6), S176. [Abstract].
   Web of Science ®Google Scholar
• Olsson, A. O.; Baker, S. E.; Nguyen, J. V.; Romanoff, L. C.; Udunka, S. O.; Walker, R. D.; Flemmen, K. L.; Barr, D. B. A Liquid Chromatography-Tandem Mass Spectrometry Multiresidue Method for Quantification of Specific Metabolites of Organophosphorus Pesticides, Synthetic Pyrethroids, Selected Herbicides, and DEET in Human Urine. Anal. Chem. 2004, 76(9), 2453–2461.
   PubMed Web of Science ®Google Scholar
• Panuwet, P.; Restrepo, P. A.; Magsumbol, M.; Jung, K. Y.; Montesano, M. A.; Needham, L. L.; Barr, D. B. An improved high-performance liquid chromatography-tandem mass spectrometric method to measure atrazine and its metabolites in human urine. J Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2010, 878, 957–962.
   PubMed Web of Science ®Google Scholar
• Panuwet, P.; Nguyen, J. V.; Wade, E. L.; D'Souza, P. E.; Ryan, P. B.; Barr, D. B. Quantification of Melamine in Human Urine Using Cation-Exchange Based High Performance Liquid Chromatography Tandem Mass Spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2012, 887, 48–54.
   PubMed Web of Science ®Google Scholar
• Picciano, M. F. Nutrient Composition of Human Milk. Pediatr. Clin. North Am. 2001, 48(1), 53–67.
   PubMed Web of Science ®Google Scholar
• Sangster, T.; Spence, M.; Sinclair, P.; Payne, R.; Smith, C. Unexpected Observation of Ion Suppression in a Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometric Bioanalytical Method. Rapid Commun. Mass Spectrom. 2004, 18(12), 1361–1364.
   PubMed Web of Science ®Google Scholar
• Schenck, F. J.; Lehotay, S. J. Does Further Clean-Up Reduce the Matrix Enhancement Effect in Gas Chromatographic Analysis of Pesticide Residues in Food? J. Chromatogr. A 2000, 868(1), 51–61.
   PubMed Web of Science ®Google Scholar
• Schmidt, A.; Karas, M.; Dülcks, T. Effect of Different Solution Flow Rates on Analyte Ion Signals in Nano-ESI MS, or: When Does ESI Turn into Nano-ESI? J. Am. Soc. Mass Spectrom. 2003, 14(5), 492–500.
   PubMed Web of Science ®Google Scholar
• Souverain, S.; Rudaz, S.; Veuthey, J. L. Matrix Effect in LC-ESI-MS and LC-APCI-MS with Off-Line and On-Line Extraction Procedures. J. Chromatogr. A 2004, 1058(1–2), 61–66.
   PubMed Web of Science ®Google Scholar
• Sterner, J. L.; Johnston, M. V.; Nicol, G. R.; Ridge, D. P. Signal Suppression in Electrospray Ionization Fourier Transform Mass Spectrometry of Multi-component Samples. J. Mass Spectrom. 2000, 35(3), 385–391.
   PubMed Web of Science ®Google Scholar
• Sviridov, D.; Hortin, G. L. Urine Albumin Measurement: Effects of Urine Matrix Constituents. Clin. Chim. Acta 2009, 404(2), 140–143.
   PubMed Web of Science ®Google Scholar
• Tang, L.; Kebarle, P. Dependence of Ion Intensity in Electrospray Mass-Spectrometry on the Concentration of the Analytes in the Electrosprayed Solution. Anal. Chem. 1993, 65(24), 3654–3668.
   Web of Science ®Google Scholar
• Taylor, P. J. Matrix Effects: The Achilles Heel of Quantitative High-Performance Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Clin. Biochem. 2005, 38(4), 328–334.
   PubMed Web of Science ®Google Scholar
• U.S. Centers for Disease Control and Prevention. Laboratory Procedure Manual: Bisphenol A and Other Environmental Phenols in Urine; U.S. Centers for Disease Control and Prevention: Atlanta, GA, 2009. http://www.cdc.gov/nchs/data/nhanes/nhanes_05_06/eph_d_met_phenols_parabens.pdf
   Google Scholar
• U.S. Food and Drug Administration. Guidance for Industry: Bioanalytical Method Validation; U.S. Department of Health and Human Services: Washington, DC, 2001.
   Google Scholar
• U.S. Food and Drug Administration. Guidance for Industry: Bioanalytical Method Validation. Draft Guidance; U.S. Department of Health and Human Services: Washington, DC, 2013.
   Google Scholar
• Van Eeckhaut, A.; Lanckmans, K.; Sarre, S.; Smolders, I.; Michotte, Y. Validation of Bioanalytical LC-MS/MS Assays: Evaluation of Matrix Effects. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2009, 877(23), 2198–2207.
   PubMed Web of Science ®Google Scholar
• Viswanathan, C. T.; Bansal, S.; Booth, B.; DeStefano, A. J.; Rose, M. J.; Sailstad, J.; Shah, V. P.; Skelly, J. P.; Swann, P. G.; Weiner, R. Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and Ligand Binding Assays. Pharm. Res. 2007, 24(10), 1962–1973.
   PubMed Web of Science ®Google Scholar
• Whitehead, R. D., Jr.; Montesano, M. A.; Jayatilaka, N. K.; Buckley, B.; Winnick, B.; Needham, L. L.; Barr, D. B. Method for Measurement of the Quaternary Amine Compounds Paraquat and Diquat in Human Urine Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2010, 878(27), 2548–2553.
   PubMed Web of Science ®Google Scholar
• World Health Organization. (1996). Biological Monitoring of Chemical Exposure in the Workplace: Guidelines; Contribution to the International Programme on Chemical Safety (IPCS); World Health Organization: Geneva, Switzerland; Vol. 1. http://whqlibdoc.who.int/hq/1996/WHO_HPR_OCH_96.1.pdf
   Google Scholar
• Xia, Y. Q.; Jemal, M. Phospholipids in Liquid Chromatography/Mass Spectrometry Bioanalysis: Comparison of Three Tandem Mass Spectrometric Techniques for Monitoring Plasma Phospholipids, the Effect of Mobile Phase Composition on Phospholipids Elution and the Association of Phospholipids with Matrix Effects. Rapid Commun. Mass Spectrom. 2009, 23(14), 2125–2138.
   PubMed Web of Science ®Google Scholar
• Yu, S.; Xu, X. M. Study of Matrix-Induced Effects in Multi-residue Determination of Pesticides by Online Gel Permeation Chromatography-Gas Chromatography/Mass Spectrometry. Rapid Commun. Mass Spectrom. 2012, 26(8), 963–977.
   PubMed Web of Science ®Google Scholar