Modern Assay Techniques for Cancer Drugs: Electroanalytical and Liquid Chromatography Methods

References

• Serlin, R. C.; Mendoza, T. R.; Nakamura, Y.; Edwards, K. R.; Cleeland, C. S. When Is Cancer Pain Mild, Moderate or Severe? Grading Pain Severity by Its Interference with Function. Pain. 1995, 61, 277–284.
   PubMed Web of Science ®Google Scholar
• Kamb, A.; Wee, S.; Lengauer, C. Why is Cancer Drug Discovery so Difficult? Nat. Rev. Drug. Discov. 2007, 6, 115–120.
   PubMed Web of Science ®Google Scholar
• Cairns, R. A.; Harris, I. S.; Mak, T. W. Regulation of Cancer Cell Metabolism. Nat. Rev. Cancer. 2011, 11, 85–95.
   PubMed Web of Science ®Google Scholar
• Fuchs, E. J.; Matzinger, P. Is Cancer Dangerous to the Immune System? Semin. Immunol. 1996, 8, 271–280.
   PubMedGoogle Scholar
• van den Beuken-van Everdingen, M.; de Rijke, J.; Kessels, A.; Schouten, H.; van Kleef, M.; Patijn, J. Prevalence of Pain in Patients with Cancer: A Systematic Review of the past 40 Years. Ann. Oncol. 2007, 18, 1437–1449.
   PubMed Web of Science ®Google Scholar
• Isanbor, C.; O’Hagan, D. Fluorine in Medicinal Chemistry: A Review of anti-Cancer Agents. J. Fluorine. Chem. 2006, 127, 303–319.
   Web of Science ®Google Scholar
• Denny, W. A. DNA-Intercalating Ligands as Anti-Cancer Drugs: Prospects for Future Design. Anticancer. Drug. Des. 1989, 4, 241–263.
   PubMedGoogle Scholar
• Wheate, N. J.; Collins, J. G. Multi-Nuclear Platinum Complexes as Anti-Cancer Drugs. Coordination Chem. Rev. 2003, 241, 133–145.
   Web of Science ®Google Scholar
• Hambley, T. W. The Influence of Structure on the Activity and Toxicity of Pt anti-Cancer Drugs. Coordination. Chem. Rev. 1997, 166, 181–223.
   Web of Science ®Google Scholar
• Tsugane, S.; Sasazuki, S. Diet and the Risk of Gastric Cancer: Review of Epidemiological Evidence. Gastric. Cancer. 2007, 10, 75–83.
   PubMed Web of Science ®Google Scholar
• Petronelli, A.; Pannitteri, G.; Testa, U. Triterpenoids as New Promising Anticancer Drugs. Anticancer. Drugs. 2009, 20, 880–892.
   PubMed Web of Science ®Google Scholar
• Tibshirani, R.; Hastie, T.; Narasimhan, B.; Chu, G. Diagnosis of Multiple Cancer Types by Shrunken Centroids of Gene Expression. Proc. Natl. Acad. Sci. USA. 2002, 99, 6567–6572.
   PubMed Web of Science ®Google Scholar
• Peng, S.; Xu, Q.; Ling, X. B.; Peng, X.; Du, W.; Chen, L. Molecular Classification of Cancer Types from Microarray Data Using the Combination of Genetic Algorithms and Support Vector Machines. FEBS. Lett. 2003, 555, 358–362.
   PubMed Web of Science ®Google Scholar
• Lee, Y.; Lee, C.-K. Classification of Multiple Cancer Types by Multicategory Support Vector Machines Using Gene Expression Data. Bioinformatics. 2003, 19, 1132–1139.
   PubMed Web of Science ®Google Scholar
• Nussbaumer, S.; Bonnabry, P.; Veuthey, J. L.; Fleury-Souverain, S. Analysis of Anticancer Drugs: A Review. Talanta. 2011, 85, 2265–2289.
   PubMed Web of Science ®Google Scholar
• Rauf, S.; Gooding, J. J.; Akhtar, K.; Ghauri, M. A.; Rahman, M.; Anwar, M. A.; Khalid, A. M. Electrochemical Approach of Anticancer Drugs–DNA Interaction. J. Pharmaceut. Biomed. Anal. 2005, 37, 205–217.
   PubMed Web of Science ®Google Scholar
• Jordan, M. A.; Wilson, L. Microtubules as a Target for Anticancer Drugs. Nat. Rev. Cancer. 2004, 4, 253–265.
   PubMed Web of Science ®Google Scholar
• Ozkan, S. A.; Kauffmann.; J. M.; Zuman, P. Electroanalytical Techniques Most Frequently Used in Drug Analysis. Electroanalysis in Biomedical and Pharmaceutical Sciences 2015, DOI:10.1007/978-3-662-47138-8_3.
   Google Scholar
• Wang, J. Analytical Electrochemistry. Hoboken, New Jersey: John Wiley & Sons, Inc., 2006.
   Google Scholar
• Scholz, F.; Stojek, Z.; Inzelt, G.; Marken, F.; Neudeck, A.; Bond, A. M.; Lovric, M.; Retter, U.; Lohse, H.; Compton, R. G.; et al. Electroanalytical Methods: Guide to Experiments and Applications. Boston MA: Springer 2010.
   Google Scholar
• Palacek, E.; Scheller.; F.; Wang, J. Electrochemistry of Nucleic Acids and Proteins:Towards Electrochemical Sensors for Genomics and Proteomics. New York: Elsevier Sci. 2005.
   Google Scholar
• Gosser, D. K. Cyclic Voltammetry. New York: VCH 1994.
   Google Scholar
• Vire, J. C.; Kauffmann, J. M. Trends in Electrochemistry in Drug Analysis. Curr. Top. Electrochem. 1994., 3, 493–515.
   Google Scholar
• McCreery, R. L. Physical Methods of Chemistry. Wiley Intersci. 1984, 2, 1–92.
   Google Scholar
• Ozkan, S. A. Electroanalytical Methods in Pharmaceutical Analysis and Their Validation. New York: HNB. Pub. 2012.
   Google Scholar
• Zhang, X.; Ju, H.; Wang, J. Electrochemical Sensors, Biosensors and Their Biomedical Applications. Burlington, USA: Elsevier. 2008.
   Google Scholar
• Brett, C. M. A. Electrochemistry. Principles, Methods and Applications. Oxford, England: Oxford University Press. 1993.
   Google Scholar
• Greef, R.; Peat, R.; Peter, L. M.; Pletcher, D. Instrumental Methods in Electrochemistry. Chichester: Ellis Horwood. 1990.
   Google Scholar
• Hart, J. P. Electroanalysis of Biologically Important Compounds. Chichester: Ellis Horwood. 1990.
   Google Scholar
• Smyth, M. R.; Vos, J. G. Comprehensive Analytical Chemistry. Elsevier Sci. 1992, 84, 1–120.
   Google Scholar
• Kissinger, P. T.; Heineman, W. R. Laboratory Techniques in Electroanalytical Chemistry. Marcel Dekker. 1996.
   Google Scholar
• Özkan, S. A.; Uslu, B.; Aboul-Enein, H. Y. Analysis of Pharmaceuticals and Biological Fluids Using Modern Electroanalytical Techniques. Crit. Rev. Anal. Chem. 2003, 33, 155–181.
   Web of Science ®Google Scholar
• Chen, J.; Fu, B.; Liu, T.; Yan, Z.; Li, K. A Graphene Oxide-DNA Electrochemical Sensor Based on Glassy Carbon Electrode for Sensitive Determination of Methotrexate. Electroanalysis. 2018, 30, 288–295.
   Web of Science ®Google Scholar
• Zhang, Q. Electrochemical Determination of the Anticancer Drug Capecitabine Based on a Graphene-Gold Nanocomposite- Modified Glassy Carbon Electrode. Int. J. Electrochem. Sci. 2017, 12, 10773–10782.
   Google Scholar
• Hadi, M.; Mollaei, T.; Ehsani, A. Graphene Oxides/Multi-Walled Carbon Nanotubes Hybrid-Modified Carbon Electrodes for Fast and Sensitive Voltammetric Determination of the Anticancer Drug 5-Fluorouracil in Spiked Human Plasma Samples. Chem. Pap. 2018, 72, 431–439.
   Web of Science ®Google Scholar
• Martínez-Rojas, F.; Del Valle, M. A.; Isaacs, M.; Ramírez, G.; Armijo, F. Electrochemical Behaviour Study and Determination of Guanine, 6-Thioguanine, Acyclovir and Gancyclovir on Fluorine-Doped SnO 2 Electrode. Application in Pharmaceutical Preparations. Electroanalysis. 2017, 29, 2888–2895.
   Web of Science ®Google Scholar
• Arkan, E.; Paimard, G.; Moradi, K. A Novel Electrochemical Sensor Based on Electrospun TiO 2 Nanoparticles/Carbon Nanofibers for Determination of Idarubicin in Biological Samples. Electroanal. Chem. 2017, 801, 480–487.
   Google Scholar
• Brycht, M.; Kaczmarska, K.; Uslu, B.; Ozkan, S. A.; Skrzypek, S. Sensitive Determination of Anticancer Drug Imatinib in Spiked Human Urine Samples by Differential Pulse Voltammetry on Anodically Pretreated Boron-Doped Diamond Electrode. Diamond Related Materials. 2016, 68, 13–22.
   Web of Science ®Google Scholar
• Hatamluyi, B.; Es'haghi, Z. A Layer-by-Layer Sensing Architecture Based on Dendrimer and Ionic Liquid Supported Reduced Graphene Oxide for Simultaneous Hollow-Fiber Solid Phase Microextraction and Electrochemical Determination of anti-Cancer Drug Imatinib in Biological Samples. Electroanal. Chem. 2017, 801, 439–449.
   Google Scholar
• Karadas-Bakirhan, N.; Patris, S.; Ozkan, S. A.; Can, A.; Kauffmann, J. M. Determination of the Anticancer Drug Sorafenib in Serum by Adsorptive Stripping Differential Pulse Voltammetry Using a Chitosan/Multiwall Carbon Nanotube Modified Glassy Carbon Electrode. Electroanalysis. 2016, 28, 358–365.
   Web of Science ®Google Scholar
• Liu, Y.; Wei, M.; Hu, Y.; Zhu, L.; Du, J. An Electrochemical Sensor Based on a Molecularly Imprinted Polymer for Determination of Anticancer Drug Mitoxantrone. Sens. Actuators B. Chem. 2018, 255, 544–551.
   Web of Science ®Google Scholar
• Manjunatha, J. G. Surfactant Modified Carbon Nanotube Paste Electrode for the Sensitive Determination of Mitoxantrone Anticancer Drug. J. Electrochem. Sci. Eng. 2017, 7, 39–49.
   Web of Science ®Google Scholar
• Hashemzadeh, N.; Hasanzadeh, M.; Shadjou, N.; Eivazi-Ziaei, J.; Khoubnasabjafari, M.; Jouyban, A. Graphene Quantum Dot Modified Glassy Carbon Electrode for the Determination of Doxorubicin Hydrochloride in Human Plasma. J. Pharm. Anal. 2016, 6, 235–241.
   PubMed Web of Science ®Google Scholar
• Materon, E. M.; Wong, A.; Klein, S. I.; Liu, J.; Sotomayor, M. D. P. T. Multi-Walled Carbon Nanotubes Modified Screen-Printed Electrodes for Cisplatin Detection. Electrochim. Acta. 2015, 158, 271–276.
   Web of Science ®Google Scholar
• Ribeiro, J. A.; Silva, F.; Pereira, C. M. Electrochemical Study of the Anticancer Drug Daunorubicin at a Water/Oil Interface: Drug Lipophilicity and Quantification. Anal. Chem. 2013, 85, 1582–1590.
   PubMed Web of Science ®Google Scholar
• Temerk, Y. M.; Ibrahim, H. S. M. Individual and Simultaneous Square Wave Voltammetric Determination of the Anticancer Drugs Emodin and Irinotecan at Renewable Pencil Graphite Electrodes. J. Brazilian Chem. Soc. 2013, 24, 1669–1678.
   Web of Science ®Google Scholar
• Bozal-Palabiyik, B.; Dogan-Topal, B.; Uslu, B.; Can, A.; Ozkan, S. A. Sensitive Voltammetric Assay of Etoposide Using Modified Glassy Carbon Electrode with a Dispersion of Multi-Walled Carbon Nanotube. J. Solid. State. Electrochem. 2013, 17, 2815–2822.
   Web of Science ®Google Scholar
• Kurbanoglu, S.; Dogan-Topal, B.; Uslu, B.; Can, A.; Ozkan, S. A. Electrochemical Investigations of the Anticancer Drug Idarubicin Using Multiwalled Carbon Nanotubes Modified Glassy Carbon and Pyrolytic Graphite Electrodes. Electroanalysis. 2013, 25, 1473–1482.
   Web of Science ®Google Scholar
• Karadas, N.; Sanli, S.; Akmese, B.; Dogan-Topal, B.; Can, A.; Ozkan, S. A. Analytical Application of Polymethylene Blue-Multiwalled Carbon Nanotubes Modified Glassy Carbon Electrode on Anticancer Drug Irinotecan and Determination of Its Ionization Constant Value. Talanta. 2013, 115, 911–919.
   PubMed Web of Science ®Google Scholar
• Rafique, B.; Khalid, A. M.; Akhtar, K.; Jabbar, A. Interaction of Anticancer Drug Methotrexate with DNA Analyzed by Electrochemical and Spectroscopic Methods. Biosensors and Biosens. Bioelectron. 2013, 44, 21–26.
   PubMed Web of Science ®Google Scholar
• Muti, M.; Gençdağ, K.; Nacak, F. M.; Aslan, A. Electrochemical Polymerized 5-Amino-2-Mercapto-1,3,4-Thiadiazole Modified Single Use Sensors for Detection of Quercetin. Colloids. Surf B.: Biointerfaces. 2013, 106, 181–186.
   PubMed Web of Science ®Google Scholar
• Radhapyari, K.; Kotoky, P.; Khan, R. Detection of Anticancer Drug Tamoxifen Using Biosensor Based on Polyaniline Probe Modified with Horseradish Peroxidase. Mater. Sci. Eng.: C 2013, 33, 583–587.
   PubMed Web of Science ®Google Scholar
• Karadas, N.; Ozkan, S. A. Electrochemical Preparation of Sodium Dodecylsulfate Doped over-Oxidized Polypyrrole/Multi-Walled Carbon Nanotube Composite on Glassy Carbon Electrode and Its Application on Sensitive and Selective Determination of Anticancer Drug: Pemetrexed. Talanta. 2014, 119, 248–254.
   PubMed Web of Science ®Google Scholar
• Yarman, A.; Scheller, F. W. The First Electrochemical MIP Sensor for Tamoxifen. Sensors (Basel). 2014, 14, 7647–7654.
   PubMed Web of Science ®Google Scholar
• Liu, Z.; Zhang, A.; Guo, Y.; Dong, C. Electrochemical Sensor for Ultrasensitive Determination of Isoquercitrin and Baicalin Based on DM-β-Cyclodextrin Functionalized Graphene Nanosheets. Biosens. Bioelectron. 2014, 58, 242–248.
   PubMed Web of Science ®Google Scholar
• Nejati, K.; Asadpour-Zeynali, K. Electrochemical Synthesis of Nickel-Iron Layered Double Hydroxide: Application as a Novel Modified Electrode in Electrocatalytic Reduction of Metronidazole. Mater. Sci. Eng. C Mater. Biol. Appl. ... 2014, 35, 179–184.
   PubMed Web of Science ®Google Scholar
• Florea, A.; Guo, ZZhong.; Cristea, C.; Bessueille, F.; Vocanson, F.; Goutaland, F.; Dzyadevych, S.; Săndulescu, R.; Jaffrezic-Renault, N. Anticancer Drug Detection Using a Highly Sensitive Molecularly Imprinted Electrochemical Sensor Based on an Electropolymerized Microporous Metal Organic Framework. Talanta. 2015, 138, 71–76.
   PubMed Web of Science ®Google Scholar
• Ahmadi, F.; Raoof, J. B.; Ojani, R.; Baghayeri, M.; Lakouraj, M. M.; Tashakkorian, H. Synthesis of Ag Nanoparticles for the Electrochemical Detection of Anticancer Drug Flutamide. Cuihua. Xuebao/Chinese. J. Catal. 2015, 36, 439–445.
   Web of Science ®Google Scholar
• Ghoreishi, S. M.; Saeidinejad, F.; Behpour, M.; Masoum, S. Application of Multivariate Optimization to Electrochemical Determination of Methyldopa Drug in the Presence of Diclofenac at a Nanostructured Electrochemical Sensor. Sens. Actuators, B: Chem. 2015, 221, 576–585.
   Web of Science ®Google Scholar
• Congur, G.; Erdem, A.; Mese, F. Electrochemical Investigation of the Interaction between Topotecan and DNA at Disposable Graphite Electrodes. Bioelectrochemistry. 2015, 102, 21–28.
   PubMed Web of Science ®Google Scholar
• Ibrahim, H.; Temerk, Y. Novel Sensor for Sensitive Electrochemical Determination of Luteolin Based on In2O3 Nanoparticles Modified Glassy Carbon Paste Electrode. Sens. Actuators B. Chem. 2015, 206, 744–752.
   Web of Science ®Google Scholar
• Ghalkhani, M.; Beheshtian, J.; Salehi, M. Electrochemical and DFT Study of an Anticancer and Active Anthelmintic Drug at Carbon Nanostructured Modified Electrode. Mater. Sci. Eng C. 2016, 69, 1345–1353.
   PubMed Web of Science ®Google Scholar
• Shashaani, H.; Faramarzpour, M.; Hassanpour, M.; Namdar, N.; Alikhani, A.; Abdolahad, M. Silicon Nanowire Based Biosensing Platform for Electrochemical Sensing of Mebendazole Drug Activity on Breast Cancer Cells. Biosens. Bioelectron. 2016, 85, 363–370.
   PubMed Web of Science ®Google Scholar
• Bukkitgar, S. D.; Shetti, N. P. Electrochemical Behavior of an Anticancer Drug 5-Fluorouracil at Methylene Blue Modified Carbon Paste Electrode. Mater. Sci. Eng C. 2016, 65, 262–268.
   PubMed Web of Science ®Google Scholar
• Temerk, Y.; Ibrahim, M.; Ibrahim, H.; Kotb, M. Adsorptive Stripping Voltammetric Determination of Anticancer Drug Lomustine in Biological Fluids Using in Situ Mercury Film Coated Graphite Pencil Electrode. Electroanal. Chem.. 2016, 760, 135–142.
   Google Scholar
• Ruzicka, J.; Hansen, E. H. Flow Injection Analysis. Wiley 1988.
   Google Scholar
• Christian, G. D.; Dasgupta, P.; Schug, K. Analytical Chemistry, 7th Edition. Hoboken, USA: Wiley Global Education. 2013.
   Google Scholar
• Snyder, L. R.; Kirkland, J. J.; Glajch, J. L. Practical HPLC Method Development. New York, USA: Wiley. 2012.
   Google Scholar
• Ettre, L. S. Does Chromatography Really Mean Color Writing?. Chromatographia. 1970, 3, 95–96.
   Google Scholar
• Ettre, L. S.; Sakodynskii, K. I. M. S. Tswett and the Discovery of Chromatography II: Completion of the Development of Chromatography (1903–1910). Chromatographia. 1993, 35, 329–338.
   Web of Science ®Google Scholar
• Meyer, V. R. Michael Tswett’s Columns: Facts and Speculations. Chromatographia. 1992, 34, 342–346.
   Web of Science ®Google Scholar
• Sengel-Turk, C. T.; Gumustas, M.; Uslu, B.; Ozkan, S. A. in: Grumezescu, A. M. (Ed.), Design of Nanostructures for Theranostics Applications. Cambidge, USA: William Andrew Publishing. 2018. pp. 69–107.
   Google Scholar
• Sengel-Turk, C. T.; Gumustas, M.; Uslu, B.; Ozkan, S. A. in: Grumezescu, A. M. (Ed.), Nano- and Microscale Drug Delivery Systems. Cambidge, USA: Elsevier. 2017. pp. 165–195.
   Google Scholar
• Gumustas, M.; Kurbanoglu, S.; Uslu, B.; Ozkan, S. A. UPLC versus HPLC on Drug Analysis: Advantageous, Applications and Their Validation Parameters. Chromatographia. 2013, 76 (21-22), 1365–1427.
   Google Scholar
• Dong, M. W. Modern HPLC for Practicing Scientists. Hoboken, USA: John Wiley & Sons, Inc. 2006. pp. 1–14.
   Google Scholar
• Iñón, F. A.; Tudino, M. B. Advances in Flow Analysis. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. 2008. pp. 1–42.
   Google Scholar
• Wixom, R. L.; Gehrke, C. W.; Berezkin, V. G.; Janak, J. Chromatography. Hoboken, USA: John Wiley & Sons, Inc. 2010. pp. 1–13.
   Google Scholar
• Lembke, P.; Henze, G.; Cabrera, K.; Brünner.; W.; Müller, E. Handbook of Analytical Techniques. Weinheim, Germany: Wiley-VCH Verlag GmbH 2001. pp. 261–326.
   Google Scholar
• LoBrutto, R.; Kazakevich, Y. HPLC for Pharmaceutical Scientists. Hoboken, USA: John Wiley & Sons, Inc. 2007. pp. 139–239.
   Google Scholar
• Kromidas, S.; Neue, U. D.; Cheng.; Y.-F.; Lu, Z. HPLC Made to Measure. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. 2006. pp. 1–70.
   Google Scholar
• Lunn, G. HPLC Methods for Recently Approved Pharmaceuticals. Hoboken, USA: John Wiley & Sons, Inc. 2005. pp. i–xxiii.
   Google Scholar
• McCalley, D. V, Hydrophilic Interaction Chromatography. Hoboken, USA: John Wiley & Sons, Inc. 2013. pp. 1–41.
   Google Scholar
• McMaster, M. C. LC/MS. Hoboken, USA: John Wiley & Sons, Inc. 2005. pp. 1–8.
   Google Scholar
• Somsen, G. W.; Jong, G. J.; deMondello, L. C.; Lewis, A. D.; Bartle, K. Multidimensional Chromatography. Hoboken, USA: John Wiley & Sons, Ltd. 2001. pp. 251–307.
   Google Scholar
• Kromidas, S. The HPLC Expert II. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. 2017. pp. 1–25.
   Google Scholar
• Zhang, Z.; Wang, Z.; Liao, Y.; Liu, H. Applications of Nanomaterials in Liquid Chromatography: Opportunities for Separation with High Efficiency and Selectivity. J. Sep. Sci. 2006, 29, 1872–1878.
   PubMed Web of Science ®Google Scholar
• Cappiello, A.; Palma, P. Advances in the Use of Liquid Chromatography Mass Spectrometry Instrumentation Developments and Application. Amsterdam, Netherlands: Elsevier Science. 2018.
   Google Scholar
• Saito, M. History of Supercritical Fluid Chromatography: Instrumental Development. J. Biosci. Bioeng. 2013, 115, 590–599.
   PubMed Web of Science ®Google Scholar
• Speybrouck, D.; Lipka, E. Preparative Supercritical Fluid Chromatography: A Powerful Tool for Chiral Separations. J. Chromatogr A. 2016, 1467, 33–55.
   PubMed Web of Science ®Google Scholar
• West, C.; Khater, S.; Lesellier, E. Characterization and Use of Hydrophilic Interaction Liquid Chromatography Type Stationary Phases in Supercritical Fluid Chromatography. J. Chromatogr A. 2012, 1250, 182–195.
   PubMed Web of Science ®Google Scholar
• Moldoveanu, S. C.; David, V. Selection of the HPLC Method in Chemical Analysis. Amsterdam, Netherlands: Elsevier Science. 2016.
   Google Scholar
• Moldoveanu, S. C.; David, V. Amsterdam, Netherlands: Elsevier. 2013. pp. 85–114.
   Google Scholar
• Ahuja, S.; Rasmussen, H. HPLC Method Development for Pharmaceuticals. Amsterdam, Netherlands: Elsevier Science. 2007.
   Google Scholar
• Cappiello, A. Advances in LC-MS Instrumentation. Amsterdam, Netherlands: Elsevier Science. 2006.
   Google Scholar
• Fanali, S.; Haddad, P. R.; Poole.; C.; Riekkola, M. L. Liquid Chromatography: Applications. Amsterdam, Netherlands: Elsevier Science. 2017.
   Google Scholar
• Parris, N. A. Instrumental Liquid Chromatography: A Practical Manual on High Performance Liquid Chromatographic Methods. Amsterdam, Netherlands: Elsevier Science. 2011.
   Google Scholar
• Scott, R. P. W. Liquid Chromatography Detectors. Amsterdam, Netherlands: Elsevier Science. 2011.
   Google Scholar
• Macek, K.; Deyl.; Z.; Janák, J. Liquid Column Chromatography: A Survey of Modern Techniques and Applications. Amsterdam, Netherlands: Elsevier Science. 2011.
   Google Scholar
• Fanali, S.; Haddad, P. R.; Poole, C.; Riekkola, M. L. Liquid Chromatography: Fundamentals and Instrumentation. Amsterdam, Netherlands: Elsevier Science. 2017.
   Google Scholar
• Siddiqui, M. R.; AlOthman, Z. A.; Rahman, N. Analytical Techniques in Pharmaceutical Analysis: A Review. Arabian. J. Chem. 2017, 10, S1409–S1421.
   Web of Science ®Google Scholar
• Swartz, M. E. UPLCTM: An Introduction and Review. J. Liquid. Chromatogr. Related Technol. 2005, 28, 1253–1263.
   Web of Science ®Google Scholar
• Medvedev, Y. V.; Ramenskaya, G. V.; Shokhin, I. E.; Yarushok, T. A. HPLC and UPLC for Determining Drugs in Blood (a Review). Pharm. Chem. J. 2013, 47, 225–230.
   Web of Science ®Google Scholar
• Cielecka-Piontek, J.; Zalewski, P.; Jelińska, A.; Garbacki, P. UHPLC: The Greening Face of Liquid Chromatography. Chromatographia. 2013, 76, 1429–1437.
   PubMed Web of Science ®Google Scholar
• Mathias, P. I.; Connor, T. H.; B’Hymer, C. A Review of High Performance Liquid Chromatographic-Mass Spectrometric Urinary Methods for Anticancer Drug Exposure of Health Care Workers. J. Chromatogr. B. 2017, 1060, 316–324.
   PubMed Web of Science ®Google Scholar
• Derissen, E. J. B.; Hillebrand, M. J. X.; Rosing, H.; Schellens, J. H. M.; Beijnen, J. H. Development of an LC–MS/MS Assay for the Quantitative Determination of the Intracellular 5-Fluorouracil Nucleotides Responsible for the Anticancer Effect of 5-Fluorouracil. J. Pharmaceut. Biomed. Anal. 2015, 110, 58–66.
   PubMed Web of Science ®Google Scholar
• Mazzucchelli, S.; Ravelli, A.; Gigli, F.; Minoli, M.; Corsi, F.; Ciuffreda, P.; Ottria, R. LC-MS/MS Method Development for Quantification of Doxorubicin and Its Metabolite 13-Hydroxy Doxorubicin in Mice Biological Matrices: Application to a Pharmaco-Delivery Study. Biomed. Chromatogr. 2017, 31, e3863.
   Web of Science ®Google Scholar
• Respaud, R.; Quenum, L.; Plichon, C.; Tournamille, J. F.; Gyan, E.; Antier, D.; Viaud-Massuard, M. C. A Stability-Indicating, Ion-Pairing, Reversed-Phase Liquid Chromatography Method for Studies of Daunorubicin Degradation in i.v. infusion Fluids. J. Pharma. Biomed. Anal. 2013, 83, 164–170.
   PubMed Web of Science ®Google Scholar
• Wang G.; Zhao D.; Chen H.; Ding D.; Kou L.; Sun L.; Hao C.; Li X.; Jia K.; Kan Q.; Liu X.; He Z.; Sun J. Development and Validation of a UPLC–MS/MS Assay for the Determination of Gemcitabine and Its L-Carnitine Ester Derivative in Rat Plasma and Its Application in Oral Pharmacokinetics 2017, 12, 478–485. DOI:10.1016/j.ajps.2017.01.001.
   Google Scholar
• Jeong, J.-W.; Seol, Y.-H.; Hyun, H.-C.; Kim, H.-R Lee, J.-H.; Gong, Y.-D Kang, N. S.; Koo, T.-S. A Validated HPLC–MS/MS Method for the Quantification of Supinoxin in Rat Plasma and Its Application to Pharmacokinetic Study. Acta chromatogr, 2017, 29. 463–468. DOI:10.1556/1326.2016.00056.
   Web of Science ®Google Scholar
• Wang, J.; Li, Y.; Ma, W.; Wang, X.; Tu, P. Validated LC-MS/MS Method for Simultaneous Determination of Doxorubicin and Curcumin in Polymeric Micelles in Subcellular Compartments of MCF-7/Adr Cells by Protein Precipitation-Ultrasonic Breaking Method. Biomed. Chromatogr. 2017, 31, e3892.
   Web of Science ®Google Scholar
• Zhang, P.; Ling, G.; Sun, J.; Sun, Y.; Pu, X.; Wang, Z.; He, Z. Determination of Mitoxantrone in Rat Plasma by Liquid Chromatography–Tandem Mass Spectrometry Method: Application to a Pharmacokinetic Study. J. Chromatogr. B. 2010, 878, 2260–2265.
   PubMed Web of Science ®Google Scholar
• Gong, X.; Yang, L.; Zhang, F.; Liang, Y.; Gao, S.; Liu, K.; Chen, W. Validated UHPLC-MS/MS Assay for Quantitative Determination of Etoposide, Gemcitabine, Vinorelbine and Their Metabolites in Patients with Lung Cancer. Biomed. Chromatogr. 2017, 31, e3989.
   Web of Science ®Google Scholar
• Binkhorst, L.; Mathijssen, R. H. J.; Ghobadi Moghaddam-Helmantel, I. M.; de Bruijn, P.; van Gelder, T.; Wiemer, E. A. C.; Loos, W. J. Quantification of Tamoxifen and Three of Its phase-I Metabolites in Human Plasma by Liquid Chromatography/Triple-Quadrupole Mass Spectrometry. J. Pharma. Biomed. Anal. 2011, 56, 1016–1023.
   PubMed Web of Science ®Google Scholar
• Sun, Y.; Tang, D.; Chen, H.; Zhang, F.; Fan, B.; Zhang, B.; Fang, S.; Lu, Q.; Wei, Y.; Yin, J.; Yin, X. Determination of Gemcitabine and Its Metabolite in Extracellular Fluid of Rat Brain Tumor by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry Using Microdialysis Sampling after Intralesional Chemotherapy. J. Chromatogr. B. 2013, 919–920, 10–19.
   PubMed Web of Science ®Google Scholar
• Sumimoto, T.; Nakahara, R.; Sato, Y.; Itoh, H. A Quantitative Method for the Determination of Bosutinib in Human Plasma Using High-Performance Liquid Chromatography and Ultraviolet Detection. J. Clin. Lab. Anal. 2018, 32.
   PubMed Web of Science ®Google Scholar
• Yasu, T.; Momo, K.; Kobayashi, S.; Kuroda, S.; Tojo, A. Simple Determination of Plasma Ponatinib Concentration Using HPLC. Biol. Pharma. Bull. 2018, 41, 254–258.
   PubMed Web of Science ®Google Scholar
• Andriguetti, N. B.; Hahn, R. Z.; Vilela, R. M. M.; Klück, H.; Raymundo, S.; Schneider, A.; Bastiani, M. F.; Andriguetti, N. B.; Schwartsmann, G.; Antunes, M. V.; Linden, R. An Optimized High-Performance HPLC-PDA Method for the Clinical Application of Paclitaxel Therapeutic Drug Monitoring. Latin Am. J. Pharm. 2018, 37, 295–300.
   Web of Science ®Google Scholar
• Hahn, R. Z.; Arnhold, P. C.; Andriguetti, N. B.; Schneider, A.; Klück, H. M.; dos Reis, S. L.; Bastiani, M. F.; Kael, I.; da Silva, A. C. C.; Schwartsmann, G.; et al. Determination of Irinotecan and Its Metabolite SN-38 in Dried Blood Spots Using High-Performance Liquid-Chromatography with Fluorescence Detection. J. Pharma. Biomed. Anal. 2018, 150, 51–58.
   PubMed Web of Science ®Google Scholar
• Nasir, B. R.; M.; Hanif, N.; M.; Abbas, G. Reverse Phase High Performance Liquid Chromatography Method for Determination of 5-Fluorouracil in Rabbit Plasma. Acta Poloniae Pharmaceutica - Drug Res. 2017, 74, 379–383.
   PubMed Web of Science ®Google Scholar
• Furman, C.; Carpentier, R.; Barczyk, A.; Chavatte, P.; Betbeder, D.; Lipka, E. Development and Validation of a Reversed-Phase HPLC Method for the Quantification of Paclitaxel in Different PLGA Nanocarriers. Electrophoresis. 2017, 38, 2536–2541.
   PubMed Web of Science ®Google Scholar
• Kim, D. W.; Yousaf, A. M.; Li, D. X.; Kim, J. O.; Yong, C. S.; Cho, K. H.; Choi, H.-G. Development of RP-HPLC Method for Simultaneous Determination of Docetaxel and Curcumin in Rat Plasma: Validation and Stability. Asian J. Pharma. Sci. 2017, 12, 105–113.
   PubMed Web of Science ®Google Scholar
• Wang, Y.; Ren, K.; Yao, Y.; Zhang, R.; Zhou, J.; Zheng, H. Determination and Pharmacokinetic Study of Gefitinib in Rat Plasma by HPLC. Latin Am. J. Pharm. 2016, 35, 429–433.
   Web of Science ®Google Scholar
• Kaza, M.; Piórkowska, E.; Filist, M.; Rudzki, P. J. HPLC-UV Assay of Imatinib in Human Plasma Optimized for Bioequivalence Studies. Acta Poloniae Pharmaceutica - Drug Res. 2016, 73, 1495–1503.
   PubMed Web of Science ®Google Scholar
• Kumar, S.; Lather, V.; Pandita, D. Stability Indicating Simplified HPLC Method for Simultaneous Analysis of Resveratrol and Quercetin in Nanoparticles and Human Plasma. Food Chem. 2016, 197, 959–964.
   PubMed Web of Science ®Google Scholar
• Altmeyer, C.; Karam, T. K.; Khalil, N. M.; Mainardes, R. M. Tamoxifen-Loaded Poly(L-Lactide) Nanoparticles: Development, Characterization and in Vitro Evaluation of Cytotoxicity. Mater. Sci. Eng: C. 2016, 60, 135–142.
   PubMed Web of Science ®Google Scholar
• Ma, Y.; Fan, X.; Li, L. pH-Sensitive Polymeric Micelles Formed by Doxorubicin Conjugated Prodrugs for co-Delivery of Doxorubicin and Paclitaxel. Carbohydr. Polym. 2016, 137, 19–29.
   PubMed Web of Science ®Google Scholar
• Kamil, A.; Smith, D. E.; Blumberg, J. B.; Astete, C.; Sabliov, C.; Oliver Chen, C.-Y. Bioavailability and Biodistribution of Nanodelivered Lutein. Food. Chem. 2016, 192, 915–923.
   PubMed Web of Science ®Google Scholar
• Chang, D.; Gao, Y.; Wang, L.; Liu, G.; Chen, Y.; Wang, T.; Tao, W.; Mei, L.; Huang, L.; Zeng, X. Polydopamine-Based Surface Modification of Mesoporous Silica Nanoparticles as pH-Sensitive Drug Delivery Vehicles for Cancer Therapy. J. Colloid. Interface. Sci. 2016, 463, 279–287.
   PubMed Web of Science ®Google Scholar
• Wu, B.; Liang, Y.; Tan, Y.; Xie, C.; Shen, J.; Zhang, M.; Liu, X.; Yang, L.; Zhang, F.; Liu, L.; et al. Genistein-Loaded Nanoparticles of Star-Shaped Diblock Copolymer Mannitol-Core PLGA–TPGS for the Treatment of Liver Cancer. Mater. Sci. Eng. C. 2016, 59, 792–800.
   PubMed Web of Science ®Google Scholar
• Yang, Y.-C.; Cai, J.; Yin, J.; Zhang, J.; Wang, K.-L.; Zhang, Z.-T. Heparin-Functionalized Pluronic Nanoparticles to Enhance the Antitumor Efficacy of Sorafenib in Gastric Cancers. Carbohydr. Polym. 2016, 136, 782–790.
   PubMed Web of Science ®Google Scholar
• Hassanlou, S.; Rajabi, M.; Shahrasbi, A. A.; Afshar, M. Development and Validation of an Ecofriendly HPLC-UV Method for Determination of Capecitabine in Human Plasma: Application to Pharmacokinetic Studies. South Afr. J. Chem. 2016, 69, 174–179.
   Web of Science ®Google Scholar
• Eldin, N. E.; Abu Lila, A. S.; Kawazoe, K.; Elnahas, H. M.; Mahdy, M. A.; Ishida, T. Encapsulation in a Rapid-Release Liposomal Formulation Enhances the anti-Tumor Efficacy of Pemetrexed in a Murine Solid Mesothelioma-Xenograft Model. Eur. J. Pharma. Sci. 2016, 81, 60–66.
   PubMed Web of Science ®Google Scholar
• Ohgami, M.; Homma, M.; Suzuki, Y.; Naito, K.; Yamada, M.; Mitsuhashi, S.; Fujisawa, F.; Kojima, H.; Kaburagi, T.; Uchiumi, K.; et al. A Simple High-Performance Liquid Chromatography for Determining Lapatinib and Erlotinib in Human Plasma. Ther. Drug. Monitor. 2016, 38, 1–662.
   PubMed Web of Science ®Google Scholar
• Mondal, S.; Narendra, R.; Ghosh, D.; Ganapaty, S. Development and Validation of RP-HPLC and UV Spectrophotometric Methods for the Quantification of Capecitabine. Int. J. Pharm. Pharma. Sci. 2016, 8, 279–287.
   Google Scholar
• Khan, I.; Iqbal, Z.; Khan, A.; Hassan, M.; Nasir, F.; Raza, A.; Ahmad, L.; Khan, A.; Akhlaq Mughal, M. A Simple, Rapid and Sensitive RP-HPLC-UV Method for the Simultaneous Determination of Sorafenib & Paclitaxel in Plasma and Pharmaceutical Dosage Forms: Application to Pharmacokinetic Study. J. Chromatogr B. Analyt. Technol. Biomed. Life. Sci. 2016, 1033–1034, 261–270.
   PubMed Web of Science ®Google Scholar
• Mandal, B.; Mittal, N. K.; Balabathula, P.; Thoma, L. A.; Wood, G. C. Development and in Vitro Evaluation of Core–Shell Type Lipid–Polymer Hybrid Nanoparticles for the Delivery of Erlotinib in Non-Small Cell Lung Cancer. Eur. J. Pharma. Sci. 2016, 81, 162–171.
   PubMed Web of Science ®Google Scholar
• Pallavi, K.; Srinivasa Babu, P.; Kishore Babu, G. Development and Validation of UV Spectrophotometric Method and RP-HPLC Method for Estimation of Capecitabine in Bulk and Tablet Dosage Forms. Int. J. Appl. Pharma. 2016, 8, 24–29.
   Google Scholar
• Han, J.; Zhang, J.; Zhao, H.; Li, Y.; Chen, Z. Simultaneous Determination of Doxorubicin and Its Dipeptide Prodrug in Mice Plasma by HPLC with Fluorescence Detection. J. Pharma. Anal. 2016, 6, 199–202.
   PubMed Web of Science ®Google Scholar
• Lucas, A. T.; O’Neal, S. K.; Santos, C. M.; White, T. F.; Zamboni, W. C. A Sensitive High Performance Liquid Chromatography Assay for the Quantification of Doxorubicin Associated with DNA in Tumor and Tissues. J. Pharma. Biomed. Anal. 2016, 119, 122–129.
   PubMed Web of Science ®Google Scholar
• Saadat, E.; Ravar, F.; Dehghankelishadi, P.; Dorkoosh, F. A. Development and Validation of a Rapid RP-HPLC-DAD Analysis Method for the Simultaneous Quantitation of Paclitaxel and Lapatinib in a Polymeric Micelle Formulation. Sci. Pharm. 2016, 84, 333–345.
   PubMed Web of Science ®Google Scholar
• Caddeo, C.; Díez-Sales, O.; Pons, R.; Carbone, C.; Ennas, G.; Puglisi, G.; Fadda, A. M.; Manconi, M. Cross-Linked Chitosan/Liposome Hybrid System for the Intestinal Delivery of Quercetin. J. Colloid. Interface. Sci. 2016, 461, 69–78.
   PubMed Web of Science ®Google Scholar
• Annapurna, M. M.; Pramadvara.; K.; Venkatesh, B. New Liquid Chromatographic Method (Stability Indicating) for the Determination of cabazitaxel - An anti-Cancer Agent. J. Chem. Pharma. Sci. 2015, 8, 853–858.
   Google Scholar
• Minhas, M. U.; Ahmad, M.; Sohail, M.; Siddique, F. Development and Optimization of Fast and New Reversed-Phase HPLC Method for Analysis of 5-Fluorouracil in Human and Rabbit Plasma. Pak. Veter. J. 2015, 35, 71–75.
   Web of Science ®Google Scholar
• Amin, A.; Bourget, P.; Ader, F.; Vidal, F.; Neuzillet, C.; Baillet-Guffroy, A. Contribution and Limits of a Non-Intrusive Raman Spectroscopic Method Compared with HPLC for Routine Application to Pre-Delivery Analytical Control of Two Major Camptothecin Analogs: Irinotecan and Topotecan. J. Raman Spectrosc. 2015, 46, 1283–1290.
   Web of Science ®Google Scholar
• Algan, A. H.; Gumustas, M.; Karatas, A.; Ozkan, S. A. A Selective and Sensitive stability-Indicating HPLC Method for the Validated Assay of Etoposide from Commercial Dosage Form and Polymeric Tubular Nanocarriers. J. Pharma. Biomed. Anal.s 2015, 124.
   Google Scholar
• Alanazi, F. K.; Haq, N.; Radwan, A. A.; Alsarra, I. A.; Shakeel, F. Development and Validation of UHPLC-DAD Method for the Determination of Cholesteryl-Hexahydrophthaloyl-5-Fluorouracil in Lipid Nanoemulsion. J. Anal. Chem. 2015, 70, 593–599.
   Web of Science ®Google Scholar
• Li, W.; Lin, X.; Yang, Z.; Zhang, W.; Ren, T.; Qu, F.; Wang, Y.; Zhang, N.; Tang, X. A Bufadienolide-Loaded Submicron Emulsion for Oral Administration: Stability, Antitumor Efficacy and Toxicity. Int. J. Pharma. 2015, 479, 52–62.
   PubMed Web of Science ®Google Scholar
• Sezgin Bayindir, Z.; Beşikci, A.; Yüksel, N. Paclitaxel-Loaded Niosomes for Intravenous Administration: Pharmacokinetics and Tissue Distribution in Rats. Turk. J. Med. Sci. 2015, 45, 1403–1412.
   PubMed Web of Science ®Google Scholar
• Pigatto, M. C.; Mossmann, D. L.; Costa, T. D. HPLC-UV Method for Quantifying Etoposide in Plasma and Tumor Interstitial Fluid by Microdialysis: Application to Pharmacokinetic Studies. Biomed. Chromatogr. 2015, 29, 529–536.
   PubMed Web of Science ®Google Scholar
• Shah, P.; Shah, R. A Stability-Indicating RP-HPLC Method Development and Validation for the Related Substances determination of Imatinibprocess Impuritiesand Their Degradation Products in Tablet Dosage Form. Int. J. PharmTech Res. 2015, 8, 128–146.
   Google Scholar
• Kawashima, W.; Okazaki, K.; Kitahara, K.; Tomioka, M.; Abe, S.; Murayama, J.-I. Development of a Quantitative Determination of Paclitaxel Using Hplc and Its Application as a Stability Test of Paclitaxel Solution for Clinical Practice. J. Showa Med. Assoc. 2015, 75, 348–352.
   Google Scholar
• Moretton, M. A.; Cagel, M.; Bernabeu, E.; Gonzalez, L.; Chiappetta, D. A. Nanopolymersomes as Potential Carriers for Rifampicin Pulmonary Delivery. Colloids. Surf. B: Biointerf. 2015, 136, 1017–1025.
   PubMed Web of Science ®Google Scholar
• Ravisankar, P.; Niharika, A.; Anusha Rani, K.; Neeha, S. M.; Pavan, G. Development and Validation of RP-HPLC Method for Quantitative Determination of Imatinib Mesylate in Bulk Drug and Pharmaceutical Dosage Form. Der Pharmacia Lettre. 2015, 7, 102–112.
   Google Scholar
• Jiang, X.; Xin, H.; Ren, Q.; Gu, J.; Zhu, L.; Du, F.; Feng, C.; Xie, Y.; Sha, X.; Fang, X. Nanoparticles of 2-Deoxy-d-Glucose Functionalized Poly(Ethylene Glycol)-co-Poly(Trimethylene Carbonate) for Dual-Targeted Drug Delivery in Glioma Treatment. Biomaterials. 2014, 35, 518–529.
   PubMed Web of Science ®Google Scholar
• Praveen Srikumar, P.; Siva Lakshmi, T.; Kathirvel, S.; Lourdu Rani, B.; Madhavi, N. Development and Validation of Stability Indicating RP- HPLC Method for the Determination of Irinotecan in Injection Formulation. Int. J. Pharm. Pharmaceu. Sci. 2013, 5, 398–400.
   Google Scholar
• Dharmalingam, S. R.; Ramamurthy, S.; Chidambaram, K.; Nadaraju, S. A Simple HPLC Bioanalytical Method for the Determination of Doxorubicin Hydrochloride in Rat Plasma: Application to Pharmacokinetic Studies. Trop. J. Pharm. Res. 2014, 13, 409–415.
   Web of Science ®Google Scholar
• Jain, A.; Gulbake, A.; Jain, A.; Shilpi, S.; Hurkat, P.; Kashaw, S.; Jain, S. K. Development and Validation of the HPLC Method for Simultaneous Estimation of Paclitaxel and Topotecan. J. Chromatogr. Sci. 2014, 52, 697–703.
   PubMed Web of Science ®Google Scholar
• Pi, C.; Wei, Y.; Yang, H.; Zhou, Y.; Fu, J.; Yang, S.; Ye, Y.; Zhao, L. Development of a HPLC Method to Determine 5-Fluorouracil in Plasma: Application in Pharmacokinetics and Steady-State Concentration Monitoring. CP. 2014, 52, 1093–1101.
   Google Scholar
• Parveen, R.; Ahmad, F.; Iqbal, Z.; Singh, M.; Kamal, Y.; Ahmad, S. Simultaneous Estimation of anti-Cancer Terpenoids in Pharmaceutical Nanoformulation by RP-HPLC and HPTLC. Acta Chromatographica. 2014, 26, 391–400.
   Web of Science ®Google Scholar
• Bernabeu, E.; Flor, S.; Hocht, C.; Taira, C.; Chiappetta, D.; Tripodi, V.; Lucangioli, S. Development and Validation of a Highly Sensitive HPLC Method for Determination of Paclitaxel in Pharmaceutical Dosage Forms and Biological Samples. Cpa. 2014, 10, 185–192.
   Google Scholar
• Sathyamoorthy, N.; Rajendran, V.; Naveena, V. S. H.; Dhanaraju, M. D. An Approach for Validated RP-HPLC Method for the Analysis of Paclitaxel in Rat Plasma. J. Appl. Pharmaceu. Sci. 2014, 4, 73–76.
   Google Scholar
• Choi, M.; Shin, D. H.; Kim, J.-S. Repositioning of Zoledronic Acid for Breast Cancer Using Transferrin-Conjugated Liposome. J. Pharmaceu. Invest. 2013, 43, 461–469.
   Google Scholar
• Kassem, M. G.; Ezzeldin, E.; Korashy, H. M.; Mostafa, G. A. E. High-Performance Liquid Chromatographic Method for the Determination of Dasatinib in Rabbit Plasma Using Fluorescence Detection and Its Application to a Pharmacokinetic Study. J. Chromatogr B. Analyt. Technol. Biomed. Life Sci. 2013, 939, 73–79.
   PubMed Web of Science ®Google Scholar
• Caterino, M.; Casadei, G. M.; Arvonio, R.; De Francia, S.; Pirro, E.; Piccione, F. M.; Pane, F.; Ruoppolo, M. Quantification of Imatinib Plasma Levels in Patients with Chronic Myeloid Leukemia: Comparison between HPLC-UV and LC-MS/MS. Int. J. Pept. Res. Ther. 2013, 19, 109–116.
   Web of Science ®Google Scholar
• Alkharfy, K. M.; Ali Khan, R. M.; Al-Asmari, M.; Alhadeyah, B. H.; Ahmad, A. Quantitative Determination of Imatinib Stability under Various Stress Conditions. J. Pharm. Bioall. Sci. 2013, 5, 49–52.
   PubMedGoogle Scholar
• Pyla, S.; Srinivas, K.; Yvv, J.; Panda, J. Development and Validation of New Analytical Method for Paclitaxel in Bulk and Pharmaceutical Dosage Form by Reverse Phase Hplc (RP-HPLC. Int. J. Pharma. Bio Sci. 2013, 4, P534–P540.
   Google Scholar
• Raza, A.; Aman, A.; Bashir, S.; Ahmad, B.; Irfan, J.; Mehta, J.; D.;Gill, H. S.; Khan, A.; Alam, M.; Schätzlein, A. G. Rapid and Sensitive Liquid Chromatographic Method for Determination of Etoposide in Plasma and Biological Samples. J. Liquid. Chromatogr. Relat. Technol. 2013, 36, 2796–2813.
   Web of Science ®Google Scholar
• Haq, N.; Shakeel, F.; Alanazi, F. K.; Radwan, A. A.; Ali, M.; Alsarra, I. A. Development and Validation of an Isocratic, Sensitive and Facile RP-HPLC Method for Rapid Analysis of 5-Fluorouracil and Stability Studies under Various Stress Conditions. Asian J. Chem. 2013, 25, 7177–7182.
   Web of Science ®Google Scholar
• Palade, L.; Popovici, I.; Popa, G.; Cojocaru, I. Elaboration and Validation of an HPLC Method for the Quantitative Assay of 5-Fluorouracil. Farmacia. 2013, 61, 526–532.
   Web of Science ®Google Scholar