The development and release of maize fortified with provitamin A carotenoids in developing countries

References

• Babu, R., N. P. Rojas, S. Gao, N. P. Yan, and K. Pixley. 2012. Validation of the effects of molecular marker polymorphisms in LcyE and CrtRB1 on provitamin A concentrations for 26 tropical maize populations. Theor. Appl. Gen. 126:389–99.
   PubMed Web of Science ®Google Scholar
• Black, R. E., L. H. Allen, Z. A. Bhutta, L. E. Caulfield, M. de Onis, M. Ezzati, C. Mathers, and J. Rivera. 2008. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371:243–60.
   PubMed Web of Science ®Google Scholar
• Brunson, A. M., and F. W.. Quackenbush. 1962. Breeding corn with high provitamin A in the grain. Crop Sci. 2:344–47.
   Google Scholar
• Burt, A. J., C. M. Grainger, J. C. Young, B. J. Shelp, and E. A. Lee. 2010. Impact of postharvest handling on carotenoid concentration and composition in high-carotenoid maize (Zea mays L.) kernels. J. Agric. Food Chem. 14:8286–92.
   Google Scholar
• Boon, C. S., D. J. Mc Clements, J. Weiss, and E. A. Decker. 2010. Factors influencing the chemical stability of carotenoids in foods. Crit. Rev. Food Sci. Nutr. 50:515–32.
   PubMed Web of Science ®Google Scholar
• Brunson, A. M., and F. W. Quackenbush. 1962. Breeding corn with high provitamin A in the grain. Crop Sci. 2:344–47.
   Google Scholar
• Cattivelli, L., F. Rizza, F.-W. Badeck, E. Mazzucotelli, A. M. Mastrangelo, E. Francia, C. Mare, A. Tondelli, and A. M. Stanca. 2008. Drought tolerance improvement in crop plants: An integrated view from breeding to genomics. Field Crops Res. 105:1–14.
   Web of Science ®Google Scholar
• Chandler, K., A. E. Lipka, B. F. Owens, H. Li, E. S. Buchler, T. Rocheford, and M. E. Gore. 2013. Genetic analysis of visually scored orange kernel colour in maize. Crop Sci. 53:189–00.
   Web of Science ®Google Scholar
• Chao, B., R. M. Twyman, G. Farre, G. Sanahuja, P. Christou, T. Camell, and C. Zhu. 2011. A golden era provitamin A enhancement in diverse crops. In Vitro Cell. Dev. Biol.-Plant. 47:205–21.
   Web of Science ®Google Scholar
• Chowdhury, S., J. V. Meenakshi, K. Tomlins, and C. Owori. 2009. Are consumers willing to pay more for biofortified foods? Evidence from a field experiment in Uganda. In HarvestPlus Working Paper 3. Washington DC.
   Google Scholar
• Christou, P., and R. M. Twyman. 2004. The potential of genetically enhanced plants to address food insecurity. Nutr. Res. Rev. 17:23–42.
   PubMed Web of Science ®Google Scholar
• Combs, G. F., R. M. Welch, J. M. Duxbury, N. T. Uphoff, and M. C. Nesheim. 1996. Food-based approaches to preventing micronutrient malnutrition: an international research agenda. Ithaca, NY: Cornell International Institute for Food, Agriculture, and Development, Cornell University.
   Google Scholar
• Darnton-Hill, I., and R. Nalubola. 2002. Fortification strategies to meet micronutrient needs: successes and failures. Proc. Nutr. Sci. 61:231–41.
   PubMed Web of Science ®Google Scholar
• Dawe, D., and L. Unnevehr. 2007. Crop case study: GMO Golden Rice in Asia with enhanced vitamin A benefits for consumers. AgBioForum 10:154–60.
   Google Scholar
• De Groote, H., and S. C. Kimenju 2008. Comparing consumer preferences for color 29 and nutritional quality in maize: Application of a semi-double-bound logistic model on urban consumers in Kenya. Food Policy 33:362–70.
   Web of Science ®Google Scholar
• De Moura, F. F., A. Miloff, and E. Boy. 2015. Retention of provitamin A carotenoids in staple crops targeted for biofortification in Africa: cassava, maize and sweet potato. Crit. Rev. Food Sci. Nutr. 55:1246–69.
   PubMed Web of Science ®Google Scholar
• Egesel, C. O., J. C. Wong, R. J. Lambert, and T. R. Rocheford. 2003. Combining ability of maize inbreds for carotenoids and tocopherols. Crop Sci. 43:818–23.
   Web of Science ®Google Scholar
• Food and Agriculture Organization of the United Nations (FAO). 1992. Maize in Human Nutrition. Rome, Italy.
   Google Scholar
• FAO/WHO. 2001. Human Vitamin and Mineral Requirements. Expert consultation on human vitamin and mineral requirements. Report of a joint FAO/WHO expert consultation – Food and nutrition division, Bangkok, Thailand.
   Google Scholar
• Fraser, P. D., and P. M. Bramley. 2004. The biosynthesis and nutritional uses of carotenoids. Progr. Lipid Res. 43:228–65.
   PubMed Web of Science ®Google Scholar
• Gadaga, T. H., R. Madzima, and N. Nembaware. 2009. Status of micronutrient nutrition in Zimbabwe: A review. Afr. J. Food, Agr. Nutr. Dev. 9:502–22.
   Google Scholar
• Garcia-Casal, M. N., and M. Layrisse. 1999. Vitamin A and β-carotene can improve non-heme iron absorption from rice, wheat and corn by humans. FASEB J. 13:A243.
   Web of Science ®Google Scholar
• Garcia-Casal, M. N., M. Layrisse, L. Solano, F. Arguello, D. Llovera, J. RamÌrez, I. Leets, and E. Tropper. 1998. Vitamin A and β-carotene can improve nonheme iron absorption from rice, wheat and corn by humans. J. Nutr. 128:646–50.
   PubMed Web of Science ®Google Scholar
• Graham, R. D., R. M. Welch, and H. E. Bouis. 2001. Addressing micronutrient malnutrition through enhancing the nutritional quality of staple foods: Principles, perspectives and knowledge gaps. Adv. Agron. 70:77–42.
   Web of Science ®Google Scholar
• Grant, W., A. Wolfaardt, and A. Louw. 2012. Maize Value Chain in the SADC Region. Technical Report, AECOM International Development and USAID/Southern Africa.
   Google Scholar
• Haas, J. D., J. L. Beard, L. E. Murray-Kolb, A. M. Del Mundo, A. Felix, and G. B. Gregorio. 2005. Iron biofortified rice improves the iron stores of non anaemic Filipino women. J. Nutr. 135:2823–30.
   PubMed Web of Science ®Google Scholar
• Harjes, C. E., T. R. Rocheford, L. Bai, T. P. Brutnell, C. B. Kandianis, S. G. Sowinski, A. E. Stapleton, R. Vallabhaneni, M. Williams, E. T. Wurtzel, J. Yan, and E. S. Buckler. 2008. Natural genetic variation in lycopene epsilon-cyclase tapped for maize biofortification. Nature Sci. 319:330–33.
   Google Scholar
• HarvestPlus 2007. The biofortification challenge programme. Annual report, HarvestPlus program. Washington DC.
   Google Scholar
• Heying, E. K., M. Grahn, K. V. Pixley, T. Rocheford, and S. A. Tanumihardjo. 2013. High-provitamin A carotenoid (orange) maize increases hepatic vitamin A reserves of offspring in a vitamin a-depleted sow-piglet model during lactation. J. Nutr. 43:1141–46
   Google Scholar
• Hotz, C., and B. McClafferty. 2007. From harvest to health: Challenges for developing biofortified staple foods and determining their impact on micronutrient status. Food Nutr. Bul. 28:271–79.
   PubMed Web of Science ®Google Scholar
• Howe, J. A., and S. A. Tanumihardjo. 2006. Carotenoid-biofortified maize maintains adequate vitamin A status in Mongolian Gerbils. J. Nutr. 136:2562–67.
   PubMed Web of Science ®Google Scholar
• Howitt, C. A., and B. J. Pogson. 2006. Carotenoid accumulation and functions in seeds and non-green tissues. Plant, Cell Envir. 29:435–45.
   PubMed Web of Science ®Google Scholar
• Johnson, L. A. 2000. Corn: the major cereals of the Americas. In Handbook of Cereal Science and Technology, eds. K. Kulp and J. G. Ponte, 2nd ed., 31–78. New York: Dekker Inc.
   Google Scholar
• International Institute of Tropical Agriculture (IITA). 2010. New varieties to boost maize output in West and Central Africa. Report, Ibadan, Nigeria.
   Google Scholar
• Johnson, E. J. 2002. The role of carotenoids in human health. Nutr. Clin. Care 5:56–65.
   PubMedGoogle Scholar
• Kinnucan, H. W., H. Xiao, C. J. Hsia, and J. D. Jackson. 1997. Effects of health information and generic advertising on US meat demand. Amer. J. Agric. Econ. 79:13‐23.
   Web of Science ®Google Scholar
• Kurilich, A. C., and J. A. Juvik. 1999. Quantification of carotenoid and tocopherol antioxidants in Zea mays. J. Agric. Food Chem. 47:1948–55.
   PubMed Web of Science ®Google Scholar
• Labadarios, D., I. M. Moodie, and A. Van Rensburg. 2007. Selected micronutrient status: vitamin A. In National Food Consumption Survey – Fortification Baseline South Africa, 2005, ed. D., Labadarios, 409–46. Stellenbosch, South Africa: Directorate Nutrition, Department of Health.
   Google Scholar
• Layrisse, M., M. N. Garcia-Casal, L. Solano, M. A. Baron, F. Arguello, D. Llovera, J. RamÌrez, I. Leets, and E. Tropper. 1997. The role of vitamin A on the inhibitors of nonheme iron absorption: Preliminary results. J. Nutr. Biochem. 8:61–67.
   Web of Science ®Google Scholar
• Layrisse, M., M. N. GarcÌa-Casal, L. Solano, M. A. Baron, F. Arguello, D. Llovera, J. RamÌrez, I. Leets, and E. Tropper. 1998. Vitamin A reduces the inhibition of iron absorption by phytates and pholyphenols. Food Nutr. Bull. 19:3–5.
   Google Scholar
• Li, S., F. A. K. Tayie, M. F. Young, T. Rocheford, and W. S. White. 2007. Retention of provitamin A carotenoids in high β-carotene maize (Zea mays L) during traditional African household processing. J. Agric. Food Chem. 55:10744–50.
   PubMed Web of Science ®Google Scholar
• Li, S., N. Nugroho, T. Rocheford, and S. White. 2010. Vitamin A equivalence of b-carotene in b-carotene-biofortified maize porridge consumed by women. Am. J. Clin. Nutr. 92:1105–12.
   PubMed Web of Science ®Google Scholar
• Lindqvist, A., and T. Verba. 2009. Golden rice and other biofortified food crops for developing countries – challenges and potential. Report from the Bertebos Conference. Falkenberg, Sweden, 7–9 September 2008. The Royal Swedish Academy of Agriculture and Forestry in Cooperation with the Bertebos Foundation. Kungl. Skogs-och Lantbruks Akademiens Tidskrift nr 7.
   Google Scholar
• Maneesha, A., Y. Xu, R. Guo, Z. Wang, S. Li, W. White, K. Wang, and S. Rodermel. 2008. Generation of transgenic maize with enhanced provitamin A content. J. Exp. Bot. 59:3551–62.
   PubMed Web of Science ®Google Scholar
• Meenakshi, J. V., N. L. Johnson, V. M. Manyong, H. De Groote, J. Javelosa, D. R. Yanggen, F. Naher, C. Gonzalez, J. García, and E. Meng. 2010 How cost-effective is biofortification in combating micronutrient malnutrition? An ex ante assessment. World Dev. 38:64–75.
   Web of Science ®Google Scholar
• Meenakshi, J. V., Banerji, A., Manyong, V., Tomlins, K., Mittal, N., and Hamukwala. P. 2012. Using a discrete choice experiment to elicit the demand for a nutritious food: Willingness to pay for orange maize in rural Zambia. J. Health. Econ. 31:62–71.
   PubMed Web of Science ®Google Scholar
• Menkir, A., W. Liu, W. S. White, B. Maziya-Dixon, and T. Rocheford. 2008. Carotenoid diversity in tropical-adapted yellow maize inbred lines. Food Chem. 109:521–29.
   Web of Science ®Google Scholar
• Menkir, A., T. Rocheford, B. Maziya-Dixon, and S. Tanumihardjo. 2015. Exploiting natural variation in exotic germplasm for increasing provitamin-A carotenoids in tropical maize. Euphytica 205:203–17.
   Web of Science ®Google Scholar
• Menkir, A., B. Maziya-Dixon, W. Mengesha, T. Rocheford, and A. O. Alamu. 2017. Accruing genetic gain in pro-vitamin A enrichment from harnessing diverse maize germplasm. Euphytica 213:105.
   Web of Science ®Google Scholar
• Micronutrient Initiative. 2009. Investing in the future: A united call to action on vitamin and mineral deficiencies. Global report, Ottawa, Canada.
   Google Scholar
• Morawetz, U., S. Kimeju, and H. De Groote. 2006. Estimating consumers' willingness to pay for food quality with experimental auctions: The case of yellow vs fortified maize meal in Kenya. Mimeo: CIMMYT.
   Google Scholar
• Muzhingi, T., A. Langyintuo, L. Malaba, and M. Bänzinger. 2008a. Consumer acceptability of yellow maize products in Zimbabwe. Food Policy 33:352–361.
   Web of Science ®Google Scholar
• Muzhingi, T., K. J. Yeum, R. M. Russell, E. J. Johnson, J. Qin, and G. Tang. 2008b. Determination of carotenoids in yellow maize, the effects of saponification and food preparations. Int. J. Vit. Nutr. Res. 78:112–20.
   PubMed Web of Science ®Google Scholar
• Naqvi, S., C. Zhu, G. Farre, K. Ramessar, L. Bassie, J. Breitenbach, D. P. Conesa, G. Ros, G. Sandmann, T. Capell, and P. Christou. 2009. Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways. Proc. Natl. Acad. Sci. USA 106:7762–67.
   PubMed Web of Science ®Google Scholar
• Nestel, P., H. E. Bouis, J. V. Meenakshi, and W. Pfeiffer. 2006. Biofortification of staple food crops. Symposium: Food fortification in developing countries. J. Nutr. 136:1064–67.
   PubMed Web of Science ®Google Scholar
• Nuss, E. T., S. A. Arscott, K. Bresnahan, K. V. Pixley, T. Rocheford, C. Hotz, W. Siamusantu, J. Chileshe, and S. A. Tanumihardjo. 2012. Comparative intake of white-versus orange-coloured maize by Zambian children in the context of promotion of biofortified maize. Food Nutr. Bul. 33:63–71.
   PubMed Web of Science ®Google Scholar
• Nuss, E. T., and S. A. Tanumihardjo. 2010. Maize: a paramount staple crop in the context of global nutrition. Compr. Rev. Food Sci. Food Saf. 9:417–36.
   PubMed Web of Science ®Google Scholar
• Palmer, A. C., W. Siamusantu, J. Chileshe, K. J. Schulze, M. Barffour, N. E. Craft, N. Molobeka, N. Kalungwana, M. A. Arguello, M. Mitra, B. Caswell, R. D. W. Klemm, and K. P. West. 2016. Provitamin A-biofortified maize increases serum β-carotene, but not retinol, in marginally nourished children: a cluster-randomized trial in rural Zambia. Am. J. Clin. Nutr. 104:181–90.
   PubMed Web of Science ®Google Scholar
• Pfeiffer, W. H., and B. McClafferty. 2007. HarvestPlus: Breeding crops for better nutrition. Crop Sci. 47:S88–05.
   Web of Science ®Google Scholar
• Pillary, K., J. Derera, M. Siwela, and F. J. Veldman. 2011. Consumer acceptance of yellow, provitamin A-biofortified maize in Kwa-Zulu-Natal. S. Afr. J. Clin. Nutr. 24:186–91.
   Google Scholar
• Pixley, K., R. Babu, J. Yan, and N. Palacios-Rojas. 2010 Challenges, progress, and state of breeding for pro-vitamin A. First Global Conference on Biofortification: From Discovery to Delivery, 9–11 Nov. 2010. Washington, D.C.
   Google Scholar
• Prasanna, B. M., K. Pixley, M. L. Warburton, and C. X. Xie. 2009. Molecular marker-assisted breeding options for maize improvement in Asia. Mol. Breed. 26:339–56.
   Web of Science ®Google Scholar
• Rahmathullah, L., B. A. Underwood, R. D. Thulasiraj, R. C. Milton, K. Ramaswamy, R. Rahmathullah, and G. Babu. 1990. Reduced mortality among children in Southern India receiving a small weekly dose of vitamin A. N. Engl. J. Med. 323:929–35.
   PubMed Web of Science ®Google Scholar
• Rooney, L. W., and S. O. Serna-Saldivar. 2003. Food use of whole corn and dry-milled fractions. In Corn Chemistry and Technology 2nd ed. American Association of Cereal Chemists, eds. P. J., White and L. A., Johnson, 495–35. St. Paul, MN.
   Google Scholar
• Rooney, L., and S. Serna-Saldavar. 1987. Food uses of whole corn and dry-milled fractions in corn: chemistry and technology. St. Paul, MN, USA: American Association of Cereal Chemists.
   Google Scholar
• Simon, P. W. 1992. Genetic improvement of vegetable carotene content. In Biotechnology and Nutrition. Proceedings of the Third International Symposium, eds. D. D. Bills and S-Y. Kung, 291–314. Boston: Butterworth-Heinemann.
   Google Scholar
• Simpungwe, E. 2017. Biofortification of maize. In Achieving sustainable cultivation of maize. Volume 1: From improved varieties to local applications, ed. D. Watson, Cambridge, UK: Burleigh Dodds Science Publishing.
   Google Scholar
• Stevens, R., and A. Winter-Nelson. 2008. Consumer acceptance of provitamin A biofortified maize in Maputo, Mozambique. Food Policy 33:341–51.
   Web of Science ®Google Scholar
• Suwarno, B. W., K. V. Pixley, N. Palacios-Rojas, S. M. Kaeppler, and R. Babu. 2014. Formation of heterotic groups and understanding genetic effects in a provitamin A biofortified maize breeding program. Crop Sci. 54:14–24.
   Web of Science ®Google Scholar
• Suwarno, W. B., K. V. Pixley, N. Palacios-Rojas, S. M. Kaeppler, and R. Babu. 2015. Genome-wide association analysis reveals new targets for carotenoid biofortification in maize. Theor. Appl. Gen. 128:851–64.
   PubMed Web of Science ®Google Scholar
• Tang, G. 2010. Bioconversion of dietary provitamin A carotenoids to vitamin A in humans. Am. J. Clin. Nutr. 91:1468S–73S.
   PubMed Web of Science ®Google Scholar
• Tang, G., J. Qin, G. G. Dolnikowski, R. M. Russell, and M. A. Grusak. 2009. Golden Rice is an effective source of vitamin A. Am. J. Clin. Nutr. 89:1776–83.
   PubMed Web of Science ®Google Scholar
• Tanumihardjo, S. A. 2008. Food-based approaches for ensuring adequate vitamin A nutrition. Compr. Rev. Food Sci. Food Saf. 7:373–81.
   Web of Science ®Google Scholar
• Tanumihardjo, S. A., R. M. Russel, C. B. Stephensen, B. M. Gannon, N. E. Craft, M. J. Haskell, G. Lietz, K. Schulze, and D. J. Raiten. 2016. Biomarkers of nutrition for development (BOND) – vitamin A review. J. Nutr. 146:1816S–1848S.
   PubMed Web of Science ®Google Scholar
• Tanumihardjo, S. A., A. Ball, C. Kaliwile, and K. V. Pixley. 2017. The research and implementation continuum of biofortified sweet potato and maize in Africa. Ann. N.Y. Acad. Sci. 1390:88–03.
   PubMed Web of Science ®Google Scholar
• Tschirley, D., and A. P. Santos. 1994. Who eats yellow maize? Some preliminary results of a survey of consumer maize meal preferences in Maputo, Mozambique. Staff paper number 94 -76. East Lansing: Michigan State University, Department of Agricultural Economics.
   Google Scholar
• Tumuhimbise, G. A., A. Namutebi, F. Turyashemererwa, and J. Muyonga. 2013. Provitamin A crops: acceptability, bioavailability, efficacy and effectiveness. Food Nutr. Sci. 4:430–35.
   Google Scholar
• US Department of Agriculture (USDA). 2007. USDA Table of Nutrient Retention Factors. Release 6. United States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland, USA.
   Google Scholar
• US Department of Agriculture (USDA). 2010. A new approach that saves eyesight and lives in the developing world https://www.ars.usda.gov/.
   Google Scholar
• Van Campen, D. R., and R. P. Glahn. 1999. Micronutrient bioavailability techniques: accuracy, problems and limitations. Field Crops Res. 60:93–13.
   Web of Science ®Google Scholar
• Van Jaarsveld, P. J., M. Faber, S. A. Tanumihardjo, P. Nestel, J. C. Lombard, and A. J. S. Benade. 2005. β;-Carotene- rich orange fleshed sweet potatoes improve the vitamin A status of primary school children assessed with the modified-relative-dose-response test. Amer. J. Clin. Nutr. 81:1080–87.
   PubMed Web of Science ®Google Scholar
• Vasal, S. K. 2000. The quality protein maize story. Food Nutr. Bul. 21:445–50.
   Google Scholar
• Welch, R. M., and R. D. Graham. 1999. A new paradigm for world agriculture: meeting human needs-productive, sustainable, nutritious. Field Crops Res. 60:1–10.
   Web of Science ®Google Scholar
• Welch, R. M., G. F. Combs Jr., and J. M. Duxbury. 1997. Toward a ‘Greener’ revolution. Issues Sci. Techn. 14:50–58.
   Web of Science ®Google Scholar
• Weber, E. 1987. Carotenoids and tocols of corn grain determined by HPLC. JAOCS 1129–34.
   Web of Science ®Google Scholar
• West, C. E., A. Eilander, and M. van Lieshout. 2002. Consequences of revised estimates of carotenoid bioefficacy for dietary control of vitamin A deficiency in developing countries. J. Nutr. 132:2920S–2926S.
   PubMed Web of Science ®Google Scholar
• World Bank. 2013. Vitamin A supplementation coverage rate (% of children ages 6–59 months). http://data.worldbank.org/indicator/sn.itk.vita.zs.
   Google Scholar
• World Food Programme. 2006. Micronutrient fortification: World Food Programme experiences and ways forward. Food Nutr. Bul. 27:67–75.
   PubMed Web of Science ®Google Scholar
• World Health Organization. 1999. The world health report 1999: Making a difference. Geneva, Switzerland: WHO.
   Google Scholar
• World Health Organization. 2002. The World Health Report: Reducing Risks, Promoting Healthy Life. Geneva, Switzerland: WHO.
   Google Scholar
• World Health Organization. 2009. Global prevalence of vitamin A deficiency in populations at risk 1995–2005. In: WHO Global Database on Vitamin A Deficiency, Geneva, Switzerland: WHO.
   Google Scholar
• World Health Organization. 2010. World health statistics. Geneva, Switzerland: World Health Organisation.
   Google Scholar
• World Health Organization. 2011. Serum retinol concentrations for determining the prevalence of vitamin A deficiency in populations. Vitamin and Mineral Nutrition Information System. Geneva: World Health Organization, (WHO/NMH/NHD/MNM/11.3).
   Google Scholar
• Yan, J., C. B. Kandianis, E. C. Harjes, L. Bai, E. H. Kim, X. Yang, D. J. Skinner, Z. Fu, S. Mitchell, Q. Li, M. G. S. Fernandez, M. Zaharieva, R. Babu, Y. Fu, N. Palacios, J. Li, D. DellaPenna, T. Brutnell, E. S. Buckler, M. L. Warburton, and T. Rocheford. 2010. Rare genetic variation at Zea mays crtRB1 increases β-carotene in maize grain. Nature Genet. 42:322–29.
   PubMed Web of Science ®Google Scholar
• Zhu, C., S. Naqvu, S. Gomez-Galera, A. M. Pelacho, T. Capell, and P. Christou. 2007. Transgenic strategies for the nutritional enhancement of plants. Trends Plant Sci. 12:548–55.
   PubMed Web of Science ®Google Scholar
• Zimicki, S. 1997. Promotion in Sub-Saharan Africa (Part 1). In Net gain: A new method for preventing malaria deaths, eds. C., Lengeler, J., Cattani and D., de Savigny, Ottawa, Canada.
   Google Scholar
• Zimmermann, R., and M. Qaim. 2004. Potential health benefits of Golden Rice: A Philippine case study. Food Policy 29:147–68.
   Web of Science ®Google Scholar