The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials

References

• NHLBI Obesity Education Initiative Expert Panel. 1998. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Expert panel on the identification, evaluation, and treatment of overweight in adults. The American Journal of Clinical Nutrition 68(4):899–917.
   PubMed Web of Science ®Google Scholar
• Astrup, A. 2000. Thermogenic drugs as a strategy for treatment of obesity. Endocrine 13(2):207–12.
   PubMed Web of Science ®Google Scholar
• Astrup, A., S. Toubro, S. Cannon, P. Hein, L. Breum, and J. Madsen. 1990. Caffeine: A double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. The American Journal of Clinical Nutrition 51(5):759–67.
   PubMed Web of Science ®Google Scholar
• Bakuradze, T., Boehm, N. Janzowski, C. Lang, R. Hofmann, T. Stockis, J. P. Albert, F. W. Stiebitz, H. Bytof, G. Lantz. I. et al. 2011. Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: Results from an intervention study. Molecular Nutrition & Food Research 55(5):793–7.
   PubMed Web of Science ®Google Scholar
• Boozer, C. N., P. A. Daly, P. Homel, J. L. Solomon, D. Blanchard, J. A. Nasser, R. Strauss, and T. Meredith. 2002. Herbal ephedra/caffeine for weight loss: A 6-month randomized safety and efficacy trial. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity 26(5):593–604.
   PubMed Web of Science ®Google Scholar
• Bracale, R., M. L. Petroni, S. Davinelli, U. Bracale, G. Scapagnini, M. O. Carruba, and E. Nisoli. 2014. Muscle uncoupling protein 3 expression is unchanged by chronic ephedrine/caffeine treatment: Results of a double blind, randomised clinical trial in morbidly obese females. PLoS One 9(6):e98244
   PubMed Web of Science ®Google Scholar
• Coffey, C. S., D. Steiner, B. A. Baker, and D. B. Allison. 2004. A randomized double-blind placebo-controlled clinical trial of a product containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment. International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity 28(11):1411–9.
   PubMed Web of Science ®Google Scholar
• Colker, C. M., D. S. Kaiman, G. C. Torina, T. Perlis, and C. Street. 1999. Effects of citrus aurantium extract, caffeine, and St. John's Wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Current Therapeutic Research 60(3):145–53.
   Web of Science ®Google Scholar
• Davoodi, S. H., S. J. Hajimiresmaiel, M. Ajami, A. Mohseni-Bandpei, S. A. Ayatollahi, K. Dowlatshahi, G. Javedan, and H. Pazoki-Toroudi. 2014. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss. Iranian Journal of Pharmaceutical Research : Ijpr 13(2):707–18.
   PubMed Web of Science ®Google Scholar
• DerSimonian, R., and N. Laird. 1986. Meta-analysis in clinical trials. Controlled Clinical Trials 7(3):177–88.
   PubMedGoogle Scholar
• Dulloo, A. G., C. Duret, D. Rohrer, L. Girardier, N. Mensi, M. Fathi, P. Chantre, and J. Vandermander. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. The American Journal of Clinical Nutrition 70(6):1040–5.
   PubMed Web of Science ®Google Scholar
• Dulloo, A. G., C. A. Geissler, T. Horton, A. Collins, and D. S. Miller. 1989. Normal caffeine consumption: Influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. The American Journal of Clinical Nutrition 49(1):44–50.
   PubMed Web of Science ®Google Scholar
• Dulloo, A. G., J. Seydoux, and L. Girardier. 1992. Potentiation of the thermogenic antiobesity effects of ephedrine by dietary methylxanthines: Adenosine antagonism or phosphodiesterase inhibition? Metabolism – Clinical and Experimental 41(11):1233–41.
   PubMed Web of Science ®Google Scholar
• Flegal, K. M., M. D. Carroll, C. L. Ogden, and C. L. Johnson. 2002. Prevalence and trends in obesity among US adults, 1999–2000. JAMA 288(14):1723–7.
   PubMed Web of Science ®Google Scholar
• Graham, T. E. 2001. Caffeine and exercise: Metabolism, endurance and performance. Sports Medicine (Auckland, N.Z.) 31(11):785–807.
   PubMed Web of Science ®Google Scholar
• Greenway, F. L., L. De Jonge, D. Blanchard, M. Frisard, and S. R. Smith. 2004. Effect of a dietary herbal supplement containing caffeine and ephedra on weight, metabolic rate, and body composition. Obesity Research 12(7):1152–7.
   PubMedGoogle Scholar
• Hackman, R. M., P. J. Havel, H. J. Schwartz, J. C. Rutledge, M. R. Watnik, E. M. Noceti, S. J. Stohs, J. S. Stern, and C. L. Keen. 2006. Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: A randomized controlled trial. International Journal of Obesity 30(10):1545–56.
   Web of Science ®Google Scholar
• Hamilton-Fairley, D., D. Kiddy, V. Anyaoku, R. Koistinen, M. Seppala, and S. Franks. 1993. Response of sex hormone binding globulin and insulin-like growth factor binding protein-1 to an oral glucose tolerance test in obese women with polycystic ovary syndrome before and after calorie restriction. Clinical Endocrinology 39(3):363–7.
   PubMed Web of Science ®Google Scholar
• Han, D. H., P. A. Hansen, L. A. Nolte, and J. O. Holloszy. 1998. Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions. Diabetes 47(11):1671–5.
   PubMed Web of Science ®Google Scholar
• Hursel, R., and M. S. Westerterp-Plantenga. 2009. Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss. The American Journal of Clinical Nutrition 89(3):822–30.
   PubMed Web of Science ®Google Scholar
• Kiddy, D. S., D. Hamilton-Fairley, M. Seppala, R. Koistinen, V. H. James, M. J. Reed, and S. Franks. 1989. Diet-induced changes in sex hormone binding globulin and free testosterone in women with normal or polycystic ovaries: Correlation with serum insulin and insulin-like growth factor-I. Clinical Endocrinology 31(6):757–63.
   PubMed Web of Science ®Google Scholar
• Kromhout, D. 1983. Body weight, diet, and serum cholesterol in 871 Middle-aged men during 10 years of follow-up (The Zutphen Study). The American Journal of Clinical Nutrition 38(4):591–8.
   PubMed Web of Science ®Google Scholar
• Lee, S., R. Hudson, K. Kilpatrick, T. E. Graham, and R. Ross. 2005. Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. Diabetes Care 28(3):566–72.
   PubMed Web of Science ®Google Scholar
• Liu, A. G., S. R. Smith, K. Fujioka, and F. L. Greenway. 2013. The effect of leptin, caffeine/ephedrine, and their combination upon visceral fat mass and weight loss. Obesity (Silver Spring, Md.) 21(10):1991–6.
   PubMed Web of Science ®Google Scholar
• Lynch, E., K. Liu, G. S. Wei, B. Spring, C. Kiefe, and P. Greenland. 2009. The relation between body size perception and change in body mass index over 13 years: The coronary artery risk development in young adults (CARDIA) study. American Journal of Epidemiology 169(7):857–66.
   PubMed Web of Science ®Google Scholar
• Molnar, D., K. Torok, E. Erhardt, and S. Jeges. 2000. Safety and efficacy of treatment with an ephedrine/caffeine mixture. The first double-blind placebo-controlled pilot study in adolescents. International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity 24(12):1573–8.
   PubMed Web of Science ®Google Scholar
• Moran, L. J., M. Noakes, P. M. Clifton, L. Tomlinson, C. Galletly, and R. J. Norman. 2003. Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism 88(2):812–9.
   PubMed Web of Science ®Google Scholar
• Phung, O. J., W. L. Baker, L. J. Matthews, M. Lanosa, A. Thorne, and C. I. Coleman. 2010. Effect of green tea catechins with or without caffeine on anthropometric measures: A systematic review and Meta-analysis. The American Journal of Clinical Nutrition 91(1):73–81.
   PubMed Web of Science ®Google Scholar
• Shi, X., W. Xue, S. Liang, J. Zhao, and X. Zhang. 2016. Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: A systematic review and meta-analysis. Nutrition Journal 15(1):103
   PubMedGoogle Scholar
• Souverein, O. W., C. Dullemeijer, P. van `T Veer, and H. van der Voet. 2012. Transformations of summary statistics as input in meta-analysis for linear dose-response models on a logarithmic scale: A methodology developed within EURRECA. BMC Medical Research Methodology 12(1):57.
   PubMedGoogle Scholar
• Thom, E. 2007. The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people. The Journal of International Medical Research 35(6):900–8.
   PubMed Web of Science ®Google Scholar
• Thong, F. S., and T. E. Graham. 2002a. Caffeine-induced impairment of glucose tolerance is abolished by beta-adrenergic receptor blockade in humans. Journal of Applied Physiology 92(6):2347–52.
   PubMed Web of Science ®Google Scholar
• Thong, F. S., and T. E. Graham. 2002b. The putative roles of adenosine in insulin- and exercise-mediated regulation of glucose transport and glycogen metabolism in skeletal muscle. Canadian Journal of Applied Physiology 27(2):152–78.
   PubMedGoogle Scholar
• Villareal, D. T., S. Chode, N. Parimi, D. R. Sinacore, T. Hilton, R. Armamento-Villareal, N. Napoli, C. Qualls, and K. Shah. 2011. Weight loss, exercise, or both and physical function in obese older adults. The New England Journal of Medicine 364(13):1218–29.
   PubMed Web of Science ®Google Scholar
• Westerterp-Plantenga, M. S., M. P. Lejeune, and E. M. Kovacs. 2005. Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. Obesity Research 13(7):1195–204.
   PubMedGoogle Scholar
• Wing, R. R., R. W. Jeffery, L. R. Burton, C. Thorson, L. H. Kuller, and A. R. Folsom. 1992. Change in waist-hip ratio with weight loss and its association with change in cardiovascular risk factors. The American Journal of Clinical Nutrition 55(6):1086–92.
   PubMed Web of Science ®Google Scholar
• Zheng, X., and H. Hasegawa. 2016. Administration of caffeine inhibited adenosine receptor agonist-induced decreases in motor performance, thermoregulation, and brain neurotransmitter release in exercising rats. Pharmacology, Biochemistry, and Behavior 140 :82–9.
   PubMed Web of Science ®Google Scholar
• Zheng, X. X., Y. L. Xu, S. H. Li, R. Hui, Y. J. Wu, and X. H. Huang. 2013. Effects of green tea catechins with or without caffeine on glycemic control in adults: a Meta-analysis of randomized controlled trials. The American Journal of Clinical Nutrition 97(4):750–62.
   PubMed Web of Science ®Google Scholar