564
Views
6
CrossRef citations to date
0
Altmetric
Reviews

Restoration of metabolic tempo through time-restricted eating (TRE) as the preventive measure for metabolic diseases

ORCID Icon, &

References

  • Abarca-Gómez, L., Z. A. Abdeen, and Z. A. Hamid. 2017. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 1289 million children, adolescents, and adults. The Lancet 390 (10113):2627–42. doi: 10.1016/S0140-6736(17)32129-3.
  • Anton, S. D., K. Moehl, W. T. Donahoo, K. Marosi, S. A. Lee, A. G. Mainous, C. Leeuwenburgh, and M. P. Mattson. 2017. Flipping the metabolic switch: Understanding and applying the health benefits of fasting. Obesity 26:254–68. doi: 10.1002/oby.22065.
  • Antoni, R., T. M. Robertson, M. Denise Robertson, and J. D. Johnston. 2018. A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects. Journal of Nutritional Science 7:e22. doi: 10.1017/jns.2018.13.
  • Carlson, O., B. Martin, K. S. Stote, E. Golden, S. Maudsley, S. S. Najjar, L. Ferrucci, D. K. Ingram, D. L. Longo, W. V. Rumpler, et al. 2007. Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women. Metabolism: clinical and Experimental 56 (12):1729–34. doi: 10.1016/j.metabol.2007.07.018.
  • Chaix, A., E. Manoogian, G. Melkani, and S. Panda. 2019. Time-restricted eating to prevent and manage chronic metabolic diseases. Annual Review of Nutrition 39 (1):291–25. doi: 10.1146/annurev-nutr-082018-124320.
  • Challet, E. 2019. The circadian regulation of food intake. Nature Reviews. Endocrinology 15 (7):393–405. doi: 10.1038/s474-019-0210-x.
  • Chowdhury, E. A., J. D. Richardson, G. D. Holman, K. Tsintzas, D. Thompson, and J. A. Betts. 2016. The causal role of breakfast in energy balance and health: A randomized controlled trial in obese adults. The American Journal of Clinical Nutrition 103 (3):747–56. doi: 10.3945/ajcn.115.122044.
  • Chowdhury, E. A., J. D. Richardson, K. Tsintzas, D. Thompson, and J. A. Betts. 2016. Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults. International Journal of Obesity 40 (2):305–11. doi: 10.1038/ijo.2015.154.
  • Daniele, A., M. Alessandra, L. Andrea, G. Elisa, S. Gabriella, and V. M. Cristina. 2016. Metaboloepigenetics: The emerging network in stem cell homeostasis regulation. Current Stem Cell Research & Therapy 11 (4):352–69. doi: . doi: 10.2174/1574888x11666151203223839.
  • de Nazareth, A. M. 2017. Type 2 diabetes mellitus in the pathophysiology of Alzheimer's disease. Dementia & Neuropsychologia 11 (2):105–13. doi: 10.1590/1980-57642016dn11-020002.
  • Di Francesco, A., C. Di Germanio, M. Bernier, and R. de Cabo. 2018. A time to fast. Science (New York, N.Y.) 362 (6416):770–5. doi: 10.1126/science.aau2095.
  • Ebbeling, C. B., H. A. Feldman, G. L. Klein, J. M. W. Wong, L. Bielak, S. K. Steltz, P. K. Luoto, R. R. Wolfe, W. W. Wong, and D. S. Ludwig. 2018. Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: Randomized trial. BMJ 363:k4583. doi: 10.1136/bmj.k4583.
  • Freese, J., R. J. Klement, B. Ruiz-Núñez, S. Schwarz, and H. Lötzerich. 2017. The sedentary (r)evolution: Have we lost our metabolic flexibility? F1000Research 6:1787. doi: 10.12688/f1000research.12724.2.
  • Froy, O. 2007. The relationship between nutrition and circadian rhythms in mammals. Front Neuroendocrinol 28 (2-3):61–71. doi: 10.1016/j.yfrne.2007.03.001.
  • Gabel, K., K. K. Hoddy, N. Haggerty, J. Song, C. M. Kroeger, J. F. Trepanowski, S. Panda, and K. A. Varady. 2018. Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study. Nutrition and Healthy Aging 4 (4):345–53. doi: 10.3233/NHA-170036.
  • Gill, S., and S. Panda. 2015. A smartphone app reveals erratic diurnal eating patterns in humans that can be modulated for health benefits. Cell Metabolism. 22 (5):789–98. doi: 10.1016/j.cmet.2015.09.005.
  • Goodpaster, B. H., and L. M. Sparks. 2017. Metabolic flexibility in health and disease. Cell Metabolism 25 (5):1027–36. doi: . doi: 10.1016/j.cmet.2017.04.015.
  • Hall, K. D. 2017. A review of the carbohydrate-insulin model of obesity. European Journal of Clinical Nutrition 71 (5):679. doi: 10.1038/ejcn.2016.260.
  • Hall, K. D., and J. Guo. 2017. Obesity energetics: Body weight regulation and the effects of diet composition. Gastroenterology 152 (7):1718–1727.e3. doi: 10.1053/j.gastro.2017.01.052.
  • Haskell, C. C. 1901. Perfect health: how to get it and how to keep it. London: L.N. Fowler.
  • Hutchison, A. T., P. Regmi, E. N. C. Manoogian, J. G. Fleischer, G. A. Wittert, S. Panda, and L. K. Heilbronn. 2019. Time-restricted feeding improves glucose tolerance in men at risk for Type 2 diabetes: A randomized crossover trial. Obesity (Silver Spring, Md.) 27 (5):724–732. doi: 10.1002/oby.22449.
  • Jamshed, H., R. A. Beyl, D. L. Della Manna, E. S. Yang, E. Ravussin, and C. M. Peterson. 2019. Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans. Nutrients 11 (6):1234. doi: 10.3390/nu1106:1234.
  • Kerndt, P. R., J. L. Naughton, C. E. Driscoll, and D. A. Loxterkamp. 1982. Fasting: The history, pathophysiology and complications. The Western Journal of Medicine 137 (5):379–399.
  • LeCheminant, J. D., E. Christenson, B. W. Bailey, and L. A. Tucker. 2013. Restricting night-time eating reduces daily energy intake in healthy young men: A short-term cross-over study. British Journal of Nutrition 110 (11):2108–13. doi: 10.1017/S0007114513001359.
  • Longo, V. D., and M. P. Mattson. 2014. Fasting: Molecular mechanisms and clinical applications. Cell Metabolism 19 (2):181–92. doi: 10.1016/j.cmet.2013.12.008.
  • Longo, V. D., and S. Panda. 2016. Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan. Cell Metabolism. 23 (6):1048–1059. doi: 10.1016/j.cmet.2016.06.001.
  • Ludwig, D. S., and C. B. Ebbeling. 2018. The carbohydrate-insulin model of obesity: Beyond “calories in, calories out”. JAMA Internal Medicine 178 (8):1098. doi: 10.1001/jamainternmed.2018.2933.
  • Mattson, M. P., D. B. Allison, L. Fontana, M. Harvie, V. D. Longo, W. J. Malaisse, M. Mosley, L. Notterpek, E. Ravussin, F. A. Scheer, et al. 2014. Meal frequency and timing in health and disease. Proceedings of the National Academy of Sciences of the United States of America 111 (47):16647–53. doi: 10.1073/pnas.1413965111.
  • Mattson, M. P., V. D. Longo, and M. Harvie. 2017. Impact of intermittent fasting on health and disease processes. Ageing Research Reviews 39:46–58. doi: 10.1016/j.arr.2016.10.005.
  • Mattson, M. P., K. Moehl, N. Ghena, M. Schmaedick, and A. Cheng. 2018. Intermittent metabolic switching, neuroplasticity and brain health. Nature Reviews Neuroscience 19 (2):80–80. doi: 10.1038/nrn.2017.156.
  • Mindikoglu, A. L., A. R. Opekun, S. K. Gagan, and S. Devaraj. 2017. Impact of time-restricted feeding and dawn-to-sunset fasting on circadian rhythm, obesity, metabolic syndrome, and nonalcoholic fatty liver disease. Gastroenterology Research and Practice 2017:3932491. doi: 10.1155/2017/3932491.
  • Mitchell, S. J., M. Bernier, J. A. Mattison, M. A. Aon, T. A. Kaiser, R. M. Anson, Y. Ikeno, R. M. Anderson, D. K. Ingram, and R. de Cabo. 2019. Daily fasting improves health and survival in male mice independent of diet composition and calories. Cell Metabolism 29 (1):221–228.e3. doi: 10.1016/j.cmet.2018.08.011.
  • Moro, T., G. Tinsley, A. Bianco, G. Marcolin, Q. F. Pacelli, G. Battaglia, A. Palma, P. Gentil, M. Neri, and A. Paoli. 2016. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. J Transl Med 14 (1):290. doi: 10.1186/s12967-016-1044-0.
  • Motamedi, S., I. Karimi, and F. Jafari. 2017. The interrelationship of metabolic syndrome and neurodegenerative diseases with focus on brain-derived neurotrophic factor (BDNF): Kill two birds with one stone. Metab Brain Dis 32 (3):651–665. doi: 10.1007/s11011-017-9997-0.
  • O’Neill, S., and L. O’Driscoll. 2015. Metabolic syndrome: A closer look at the growing epidemic and its associated pathologies. Obes Rev 16 (1):1–12. doi: 10.1111/obr.12229.
  • OpenStax. 2013. Overview of metabolic reactions. In Anatomy and physiology, ed. OpenStax. Houston, TX: Rice University.
  • Orellana, A., A. Vasconcelos, A. G. Paixão, C. Scavone, and E. Kawamoto. 2018. Intermittent fasting and caloric restriction: Neuroplasticity and neurodegeneration. In Handbook of famine, starvation, and nutrient deprivation, 1–18. Cham, Switzerland: Springer.
  • Panda, S. 2016. Circadian physiology of metabolism. Science (New York, N.Y.) 354 (6315):1008–1015. doi: 10.1126/science.aah4967.
  • Paoli, A., G. Tinsley, A. Bianco, and T. Moro. 2019. The influence of meal frequency and timing on health in humans: The role of fasting. Nutrients 11 (4):719. doi: 10.3390/nu11040719.
  • Paschos, G. K., and G. A. FitzGerald. 2017. Circadian clocks and metabolism: Implications for microbiome and aging. Trends in Genetics : TIG 33 (10):760–769. doi: 10.1016/j.tig.2017.07.010.
  • Patterson, R. E., G. A. Laughlin, D. D. Sears, A. Z. LaCroix, C. Marinac, L. C. Gallo, S. J. Hartman, L. Natarajan, C. M. Senger, M. E. Martínez, et al. 2015. Intermittent fasting and human metabolic health. Journal of the Academy of Nutrition and Dietetics 115 (8):1203–1212. doi: 10.1016/j.jand.2015.02.018.
  • Patterson, R. E., and D. D. Sears. 2017. Metabolic effects of intermittent fasting. Annual Review of Nutrition 37 (1):371–393. doi: 10.1146/annurev-nutr-071816-064634.
  • Peek, C. B., A. H. Affinati, K. M. Ramsey, H.-Y. Kuo, W. Yu, L. A. Sena, O. Ilkayeva, B. Marcheva, Y. Kobayashi, C. Omura, et al. 2013. Circadian Clock NAD + cycle drives mitochondrial oxidative metabolism in mice. Science (New York, N.Y.) 342 (6158):1243417. doi: 10.1126/science.1243417.
  • Petersen, M. C., D. F. Vatner, and G. I. Shulman. 2017. Regulation of hepatic glucose metabolism in health and disease. Nature Reviews. Endocrinology 13 (10):572–587. doi: 10.1038/nrendo.2017.80.
  • Potter, C., R. L. Griggs, J. M. Brunstrom, and P. J. Rogers. 2019. Breaking the fast: Meal patterns and beliefs about healthy eating style are associated with adherence to intermittent fasting diets. Appetite 133:32–39. doi: 10.1016/j.appet.2018.10.020.
  • Prince, M. I., R. T. Woods, M. Guerchet, G.-C. Ali, Y.-T. Wu, and M. A. Prina. 2015. World alzheimer report 2015—The global impact of dementia. Alzheimer's Disease International (ADI), London, UK.
  • Ravussin, E., R. A. Beyl, E. Poggiogalle, D. S. Hsia, and C. M. Peterson. 2019. Early time-restricted feeding reduces appetite and increases fat oxidation but does not affect energy expenditure in humans. Obesity (Silver Spring, Md.) 27 (8):1244–1254. doi: 10.1002/oby.22518.
  • Rehan, L., K. Laszki-Szcząchor, M. Sobieszczańska, and D. Polak-Jonkisz. 2014. SIRT1 and NAD as regulators of ageing. Life Sci 105 (1–2):1–6. doi: 10.1016/j.lfs.2014.03.015.
  • Sievert, K., S. M. Hussain, M. J. Page, Y. Wang, H. J. Hughes, M. Malek, and F. M. Cicuttini. 2019. Effect of breakfast on weight and energy intake: Systematic review and meta-analysis of randomised controlled trials. BMJ (Clinical Research ed.) 364:l42 doi: 10.1136/bmj.l42.
  • Sinclair, U. 1911. The fasting cure. British Medical Journal 1 (2632):1379–1380.
  • Smith, R. L., M. R. Soeters, R. C. I. Wust, and R. H. Houtkooper. 2018. Metabolic flexibility as an adaptation to energy resources and requirements in health and disease. Endocr. Rev 39 (4):489–517. doi: 10.1210/er.2017-00211.
  • Smith, S. T., J. C. LeSarge, and P. W. R. Lemon. 2017. Time-restricted eating in women—A pilot study. WURJ: Health and Natural Sciences 8 (1):1–6. doi: 10.5206/wurjhns.2017-18.3.
  • Stekovic, S., S. J. Hofer, N. Tripolt, M. A. Aon, P. Royer, L. Pein, J. T. Stadler, T. Pendl, B. Prietl, J. Url, et al. 2019. Alternate day fasting improves physiological and molecular markers of aging in healthy, non-obese humans. Cell Metabolism 30 (3):462–476.e6. doi: 10.1016/j.cmet.2019.07.016.
  • Stenvers, D. J., F. A. J. L. Scheer, P. Schrauwen, S. E. la Fleur, and A. Kalsbeek. 2019. Circadian clocks and insulin resistance. Nature Reviews. Endocrinology 15 (2):75–89. doi: 10.1038/s474-018-0122-1.
  • Stote, K. S., D. J. Baer, K. Spears, D. R. Paul, G. K. Harris, W. V. Rumpler, P. Strycula, S. S. Najjar, L. Ferrucci, D. K. Ingram, et al. 2007. A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. The American Journal of Clinical Nutrition 85 (4):981–8. doi: 10.1093/ajcn/85.4.981.
  • Straub, R. H. 2017. The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology 13:743–51. doi: 10.1038/nrrheum.2017.172.
  • Sutton, E. F., R. Beyl, K. S. Early, W. T. Cefalu, E. Ravussin, and C. M. Peterson. 2018. Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes. Cell Metabolism 27 (6):1212–1221.e3. doi: 10.1016/j.cmet.2018.04.010.
  • Teruya, T., R. Chaleckis, J. Takada, M. Yanagida, and H. Kondoh. 2019. Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood. Scientific Reports 9 (1):854. doi: 10.1038/s41598-018-36674-9.
  • Tinsley, G. M., J. S. Forsse, N. K. Butler, A. Paoli, A. A. Bane, P. M. La Bounty, G. B. Morgan, and P. W. Grandjean. 2017. Time-restricted feeding in young men performing resistance training: A randomized controlled trial. European Journal Sport Science 17 (2):200–207. doi: 10.1080/17461391.2016.1223173.
  • Wang, H. B., D. H. Loh, D. S. Whittaker, T. Cutler, D. Howland, and C. S. Colwell. 2018. Time-restricted feeding improves circadian dysfunction as well as motor symptoms in the Q175 mouse model of huntington’s disease. eNeuro 5 (1):ENEURO.0431-17.2017. doi: 10.1523/ENEURO.0431-17.2017.
  • Wilhelmi de Toledo, F., F. Grundler, A. Bergouignan, S. Drinda, and A. Michalsen. 2019. Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects. PLoS One 14 (1):e0209353. doi: 10.1371/journal.pone.0209353.
  • Xie, G., W. Tian, T. Wei, and F. Liu. 2015. The neuroprotective effects of β-hydroxybutyrate on Aβ-injected rat hippocampus in vivo and in Aβ-treated PC-12 cells in vitro. Free Radical Research 49 (2):139–50. doi: 10.3109/10715762.2014.987274.
  • Zisapel, N. 2018. New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. British Journal of Pharmacology 175 (16):3190–3199. doi: 10.1111/bph.14116.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.