2,701
Views
8
CrossRef citations to date
0
Altmetric
Review Articles

The role of vitamin E acetate (VEA) and its derivatives in the vaping associated lung injury: systematic review of evidence

ORCID Icon, , , , ORCID Icon &
Pages 15-23 | Received 28 Sep 2020, Accepted 30 Nov 2020, Published online: 12 Jan 2021

References

  • Aeling JL, Panagotacos PJ, Andreozzi RJ. 1973. Letter: allergic contact dermatitis to vitamin E aerosol deodorant. Arch Dermatol. 108:579–580.
  • Bernhard W. 2016. Lung surfactant: function and composition in the context of development and respiratory physiology. Ann Anat. 208:146–150.
  • Blount B, Karwowski M, Shields PG, Morel-Espinosa M, Valentin-Blasini L, Gardner M, Braselton M, Brosius CR, Caron KT, Chambers D, et al. 2019. Vitamin E acetate in bronchoalveolar-lavage fluid associated with EVALI. NEJM. 382:697–705.
  • Burbank AJ, Duran CG, Pan Y, Burns P, Jones S, Jiang Q, Yang C, Jenkins S, Wells H, Alexis N, et al. 2018. Gamma tocopherol-enriched supplement reduces sputum eosinophilia and endotoxin-induced sputum neutrophilia in volunteers with asthma. J Allergy Clin Immunol. 141:1231–1238.e1.
  • Campbell M, McKenzie JE, Sowden A, Katikireddi SV, Brennan SE, Ellis S, Hartmann-Boyce J, Ryan R, Shepperd S, Thomas J, et al. 2019. Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline. BMJ. 368:l6890.
  • Cutts S, Talboys R, Paspula C, Prempeh EM, Fanous R, Ail D. 2017. Adult respiratory distress syndrome. Ann R Coll Surg Engl. 99:12–16.
  • Goerke J. 1998. Pulmonary surfactant: functions and molecular composition. Biochim Biophys Acta. 1408:79–89.
  • Gomes EC, Allgrove JE, Florida-James G, Stone V. 2011. Effect of vitamin supplementation on lung injury and running performance in a hot, humid, and ozone-polluted environment. Scand J Med Sci Sports. 21:e452–e460.
  • Guthmann F, Kolleck I, Schachtrup C, Schlame M, Spener F, Rüstow B. 2003. Vitamin E deficiency reduces surfactant lipid biosynthesis in alveolar type II cells. Free Radic Biol Med. 34:663–673.
  • Hajimahmoodi M, Mojtahedzadeh M, Ghaffar-Natanzi N, Sadrai S, Sadeghi N, Nadjafi A, Hadadi A, Oveisi MR. 2009. Effects of vitamin E administration on APACHE II Score in ARDS patients. DARU. 17:24–28.
  • Hamahata A, Enkhbaatar P, Kraft ER, Lange M, Leonard SW, Traber MG, Cox RA, Schmalstieg FC, Hawkins HK, Whorton EB. 2008. Gamma-tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. Free Radic Biol Med. 45:425–433.
  • Hybertson BM, Chung JH, Fini MA, Lee YM, Allard JD, Hansen BN, Cho OJ, Shibao GN, Repine JE. 2005. Aerosol-administered alpha-tocopherol attenuates lung inflammation in rats given lipopolysaccharide intratracheally. Exp Lung Res. 31:283–289.
  • Kolleck I, Sinha P, Rüstow B. 2002. Vitamin E as an antioxidant of the lung: mechanisms of vitamin E delivery to alveolar type II cells. Am J Respir Crit Care Med. 166:S62–S66.
  • Kurti SP, Murphy JD, Ferguson CS, Brown KR, Smith JR, Harms CA. 2016. Improved lung function following dietary antioxidant supplementation in exercise-induced asthmatics. Respir Physiol Neurobiol. 220:95–101.
  • Leray C, Andriamampandry MD, Freund M. 1998. Simultaneous determination of homologues of vitamin E and coenzyme Q and products of a-tocopherol oxidation. J Lipid Res . 39:2099–2105.
  • Lewis JF, Veldhuizen RAW. 2006. The future of surfactant therapy during ALI/ARDS. Semin Respir Crit Care Med. 27:377–388.
  • Lu D, Yang Y, Wu X, Zeng L, Li Y, Sun C. 2015. Simultaneous determination of eight vitamin E isomers and α-tocopherol acetate in functional foods and nutritional supplements by gas chromatography - mass spectrometry. Anal Methods. 7:3353–3362.
  • Mendoza Morales RZ, Nava-Camberos EV, Rosas-Luna A, Garcés-Ramírez L, De la Cruz F, García-Dolores F. 2016. A fatal case of systemic fat embolism resulting from gluteal injections of vitamin E for cosmetic enhancement. Forensic Sci Int. 259:e1–e4.
  • Morita N, Traber MG, Enkhbataar P, Westphal M, Murakami K, Leonard SW, Cox RA, Hawkins HK, Herndon D, Traber LD, et al. 2006. Aerosolized alpha-tocopherol ameliorates acute lung injury following combined burn and smoke inhalation injury in sheep. Shock. 25:277–282.
  • Nadeem A, Raj HG, Chabra SK. 2008. Effect of vitamin E supplementation with standard treatment on oxidant-antioxidant status in chronic obstructive pulmonary disease. Ind J Med Res. 128:705.
  • European Commission. 2004. Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E. European Commission Health & Consumer Protection Directorate-General. https://ec.europa.eu/food/sites/food/files/safety/docs/sci-com_scf_out195_en.pdf
  • Pearson PJK, Lewis SA, Britton J, Fogarty A. 2004. Vitamin E supplements in asthma: a parallel group randomised placebo controlled trial. Thorax. 59:652–656.
  • PROSPERO. 2018. PROSPERO International Prospective Registry of Systematic Reviews. National Institute for Health Research.
  • Rothe H, Fautz R, Gerber E, Neumann L, Rettinger K, Schuh W, Gronewold C. 2011. Special aspects of cosmetic spray safety evaluations: principles on inhalation risk assessment. Toxicol Lett. 205:97–10.
  • Rüstow B, Haupt R, Stevens PA, Kunze D. 1993. Type II pneumocytes secrete vitamin E together with surfactant lipids. Am J Physiol. 265:L133–L139.
  • Schmidt R, Luboeinski T, Markart P, Ruppert C, Daum C, Grimminger F, Seeger W, Günther A. 2004. Alveolar antioxidant status in patients with acute respiratory distress syndrome. Eur Respir J. 24:994–999.
  • Shadi Z, Jamaati H, Mojtahedzadeh M, Hashemian SM, Fahimi F, Farzanegan B, Moghaddam G, Radmand G, Vahdani B, Nadji SA, et al. 2011. The relationship between vitamin E plasma and BAL concentrations, SOD activity and ventilatory support measures in critically ill patients. Iran J Pharm Res. 10:953–960.
  • Tangney CC, Stibolt TB, Zheutlin L, Jacobs E, Hanley M. 1989. Comparison of vitamin E levels in plasma, bronchoalveolar lavage, and lung tissues of adult pulmonary patients. J Am Coll Nutr. 8:203–214.
  • The Editors of Encyclopaedia Britannica. 2020. Surface tension. Encyclopaedia Britannica, Inc. https://www.britannica.com/science/surface-tension
  • The Newcastle-Ottawa Scale. 2014. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. The Ottawa Hospital. http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
  • Valentinuzzi M, Kohen A. 2011. Laplace’s Law [Retrospectroscope]. IEEE Pulse. 2:72–82.
  • Ward JA, Roberts RJ. 1984. Vitamin E inhibition of the effects of hyperoxia on the pulmonary surfactant system of the newborn rabbit. Pediatr Res. 18:329–334.
  • GRADE. 2019. What is GRADE? BMJ Best Practice. https://bestpractice.bmj.com/info/toolkit/learn-ebm/what-is-grade/
  • Wilkinson M, Hart A, Milan S, Sugumar K. 2014. Vitamins C and E for asthma and exercise‐induced bronchoconstriction. Cochrane Database Syst Rev. 2014:CD010749.
  • Xantus GZ. 2020. Vaping-associated lung injury-VALI facts, assumptions and opportunities: review of the present situation. Postgrad Med J. 96:61–63.
  • Xantus GZ, Gyarmathy AV, Johnson CA. 2020. Smouldering ashes – burning questions after electronic cigarette/vaping associated lung injury. Postgrad Med J. 96:686–692.
  • Xue Y, Williams TL, Li T, Umbehr J, Fang L, Wang W, Baybutt RC. 2005. Type II pneumocytes modulate surfactant production in response to cigarette smoke constituents: restoration by vitamins A and E. Toxicol in Vitro. 19:1061–1069.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.