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DNA Sequence Volume 13, 2002 - Issue 5
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Research Article

Cloning and Characterization of the Genes Coding for Antigen 85A, 85B and 85C of Mycobacterium avium subsp. paratuberculosis

Veerabadran Dheenadhayalan College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Kwang-Soon Shin College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Chao-Fu Chang College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Chin-Dong Chang College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Shih-Jon Wang College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Sean McDonough College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Patrick McDonough College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Susan Stehman College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Sang Shin College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
,
Alfonso Torres College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
&
Yung-Fu Chang College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853 USA
 show all
Pages 287-294 | Published online: 11 Jul 2009

  • Altschul, S.F. and Koonin, E.V. (1998) "Iterated profile searches with PSI-BLAST-a tool for discovery in protein databases", Trends Biochem. Sci. 23, 444 - 447
  • Altschul, S.F., Madden, T.L., Schaffer, A.A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D.J. (1997) "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25, 3389 - 3402
  • Andersen, P., Askgaard, D., Ljungqvist, L., Bennedsen, J. and Heron, I. (1991) "Proteins released from Mycobacterium tuberculosis during growth", Infect. Immun. 59, 1905 - 1910
  • Armitige, L.Y., Jagannath, C., Wanger, A.R. and Norris, S.J. (2000) "Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages", Infect. Immun. 68, 767 - 778
  • Belisle, J.T., Vissa, V.D., Sievert, T., Takayama, K., Brennan, P.J. and Besra, G.S. (1997) "Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis", Science 276, 1420 - 1422
  • Chang, Y.F., Young, R. and Struck, D.K. (1989) "Cloning and characterization of a hemolysin gene from Actinobacillus (Haemophilus) pleuropneumoniae", DNA 8, 635 - 647
  • Chang, Y.F., Lauderdale, T.L., Lee, W.Y., Shin, S.J., Jacobson, R.H., Appel, M.J. and Lein, D.H. (1993) "Expression and secretion of outer surface protein (OSP-A) of Borrelia burgdorferi from Escherichia coli", FEMS Microbiol. Lett. 109, 297 - 301
  • Cobb, A.J. and Frothingham, R. (1999) "The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis", Vet. Microbiol. 67, 31 - 35
  • Cocito, C., Gilot, P., Coene, M., de Kesel, M., Poupart, P. and Vannuffel, P. (1994) "Paratuberculosis", Clin. Microbiol. Rev. 7, 328 - 345
  • Collins, M.T. (1996) "Diagnosis of paratuberculosis", Vet. Clin. N. Am. Food Anim. Pract. 12, 357 - 371
  • Gilot, P., De Kesel, M., Machtelinckx, L., Coene, M. and Cocito, C. (1993) "Isolation and sequencing of the gene coding for an antigenic 34-kilodalton protein of Mycobacterium paratuberculosis", J. Bacteriol. 175, 4930 - 4935
  • Horwitz, M.A., Lee, B.W., Dillon, B.J. and Harth, G. (1995) "Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis", Proc. Natl Acad. Sci. USA 92, 1530 - 1534
  • Huygen, K., Van Vooren, J.P., Turneer, M., Bosmans, R., Dierckx, P. and De Bruyn, J. (1988) "Specific lymphoproliferation, gamma interferon production, and serum immunoglobulin G directed against a purified 32 kDa mycobacterial protein antigen (P32) in patients with active tuberculosis", Scand. J. Immunol. 27, 187 - 194
  • Huygen, K., Lozes, E., Gilles, B., Drowart, A., Palfliet, K., Jurion, F., Roland, I., Art, M., Dufaux, M., Nyabenda, J., et al. (1994) "Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG", Infect. Immun. 62, 363 - 370
  • Huygen, K., Content, J., Denis, O., Montgomery, D.L., Yawman, A.M., Deck, R.R., DeWitt, C.M., Orme, I.M., Baldwin, S., D'Souza, C., Drowart, A., Lozes, E., Vandenbussche, P., Van Vooren, J.P., Liu, M.A. and Ulmer, J.B. (1996) "Immunogenicity and protective efficacy of a tuberculosis DNA vaccine", Nat. Med. 2, 893 - 898
  • Kalis, C.H., Hesselink, J.W., Barkema, H.W. and Collins, M.T. (2001) "Use of long-term vaccination with a killed vaccine to prevent fecal shedding of Mycobacterium avium subsp paratuberculosis in dairy herds", Am. J. Vet. Res. 62, 270 - 274
  • Kohler, H., Gyra, H., Zimmer, K., Drager, K.G., Burkert, B., Lemser, B., Hausleithner, D., Cubler, K., Klawonn, W. and Hess, R.G. (2001) "Immune reactions in cattle after immunization with a Mycobacterium paratuberculosis vaccine and implications for the diagnosis of M. paratuberculosis and M. bovis infections", J. Vet. Med. B Infect. Dis. Vet. Public Health 48, 185 - 195
  • Kormendy, B. (1992) "Paratuberculosis vaccine in a large dairy herd", Acta Vet. Hung. 40, 171 - 184
  • Kyte, J. and Doolittle, R.F. (1982) "A simple method for displaying the hydropathic character of a protein", J. Mol. Biol. 157, 105 - 132
  • Marston, F.A.O., Lowe, P.A., Doel, M.T., Schoemaker, J.M., White, S. and Angal, S. (1984) "Purification of calf prochymosin (prorennin) synthesized in Escherichia coli", Biotec 2, 800 - 804
  • Naito, M., Ohara, N., Matsumoto, S. and Yamada, T. (1998) "The novel fibronectin-binding motif and key residues of mycobacteria", J. Biol. Chem. 273, 2905 - 2909
  • Roche, P.W., Peake, P.W., Billman-Jacobe, H., Doran, T. and Britton, W.J. (1994) "T-cell determinants and antibody binding sites on the major mycobacterial secretory protein MPB59 of Mycobacterium bovis", Infect. Immun. 62, 5319 - 5326
  • Ronning, D.R., Klabunde, T., Besra, G.S., Vissa, V.D., Belisle, J.T. and Sacchettini, J.C. (2000) "Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines", Nat. Struct. Biol. 7, 141 - 146
  • Schorey, J.S., Holsti, M.A., Ratliff, T.L., Allen, P.M. and Brown, E.J. (1996) "Characterization of the fibronectin-attachment protein of Mycobacterium avium reveals a fibronectin-binding motif conserved among mycobacteria", Mol. Microbiol. 21, 321 - 329
  • Silver, R.F., Wallis, R.S. and Ellner, J.J. (1995) "Mapping of T cell epitopes of the 30-kDa alpha antigen of Mycobacterium bovis strain bacillus Calmette-Guerin in purified protein derivative (PPD)-positive individuals", J. Immunol. 154, 4665 - 4674
  • Stabel, J.R. (1998) "Johne's disease: a hidden threat", J. Dairy Sci. 81, 283 - 288
  • Whipple, D.L., Le Febvre, R.B., Andrews, Jr., R.E. and Thiermann, A.B. (1987) "Isolation and analysis of restriction endonuclease digestive patterns of chromosomal DNA from Mycobacterium paratuberculosis and other Mycobacterium species", J. Clin. Microbiol. 25, 1511 - 1515
  • Wiker, H.G. and Harboe, M. (1992) "The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis", Microbiol. Rev. 56, 648 - 661

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