Cloning and Characterization of a New Polyketide Synthase Gene Cluster in Streptomyces aureofaciens CCM 3239

References

• Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.O., Seidman, J.S., Smith, J.A. and Struhl, K. (1995) Current Protocols in Molecular Biology (Wiley, New York).
   Google Scholar
• Bentley, S.D., Chater, K.F., Cerdeno-Tarraga, A.M., Challis, G.L., Thomson, N.R., James, K.D., Harris, D.E., Quail, M.A., Kieser, H., Harper, D., Bateman, A., Brown, S., Chandra, G., Chen, C.W., Collins, M., Cronin, A., Fraser, A., Goble, A., Hidalgo, J., Hornsby, T., Howarth, S., Huang, C.H., Kieser, T., Larke, L., Murphy, L., Oliver, K., O’Neil, S., Rabbinowitsch, E., Rajandream, M.A., Rutherford, K., Rutter, S., Seeger, K., Saunders, D., Sharp, S., Squares, R., Squares, S., Taylor, K., Warren, T., Wietzorrek, A., Woodward, J., Barrell, B.G., Parkhill, J. and Hopwood, D.A. (2002) “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)”, Nature 417, 141– 147.
   PubMed Web of Science ®Google Scholar
• Bisang, C., Long, P.F., Cortes, J., Westcott, J., Crosby, J., Matharu, A-L., Cox, R.J., Simpson, T.J., Staunton, J. and Leadlay, P.F. (1999) “A chain initiation factor common to both modular and aromatic polyketide synthases”, Nature 401, 502– 505.
   PubMed Web of Science ®Google Scholar
• Brunker, P., McKinney, K., Sterner, O., Minas, W. and Bailey, J.E. (1999) “Isolation and characterization of the naphtocyclinone gene cluster from Streptomyces arenae DSM40737 and heterologous expression pf the polyketide synthase genes”, Gene 227, 125– 135.
   PubMed Web of Science ®Google Scholar
• Chater, K.F. (1998) “Taking a genetic scalpel to the Streptomyces colony”, Microbiology 144, 1465 – 1478.
   Google Scholar
• Davis, N.K. and Chater, K.F. (1990) “Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to poly- ketide antibiotics”, Molecular Microbiology 4, 1679– 11691.
   PubMed Web of Science ®Google Scholar
• Decker, H. and Haag, S. (1995) “Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tu2717, which carries the genes fro biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation”, Journal of Bacteriology 177, 6126– 6136.
   PubMed Web of Science ®Google Scholar
• Grimm, A., Madduri, K., Ali, A. and Hutchinson, C.R. (1994) “Characterization of the Streptomyces peucetius ATCC2905 genes encoding doxorubicin polyketide synthase”, Gene 151, 1– 10.
   PubMed Web of Science ®Google Scholar
• Han, L., Yang, K., Ramalingam, E., Mosher, R.H. and Vining, L.C. (1994) “Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezualeae ISP5230”, Microbiology 140, 3379– 3389.
   PubMed Web of Science ®Google Scholar
• Hopwood, D.A. (1997) “Genetic contributions to understanding polyketide synthases”, Chemical Reviews 97, 2465– 2497.
   PubMed Web of Science ®Google Scholar
• Horinouchi, S., Hara, O. and Beppu, T. (1983) “Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans”, Journal of Bacterio- logy 155, 1238– 1248.
   PubMed Web of Science ®Google Scholar
• Hullo, M-F., Moszer, I., Danchin, A. and Marti-Verstraete, I. (2001) “CotA of Bacillus subtilis is a copper-dependent laccase”, Journal of Bacteriology 183, 5426– 5430.
   PubMed Web of Science ®Google Scholar
• Ichinose, K., Bedford, D.J., Tornus, D., Bechtohold, A., Bibb, M.J., Revill, W.P., Floss, H.G. and Hopwood, D.A. (1998) “The granaticin biosynthetic gene cluster of Streptomyces violaceor- uber Tu22: sequence analysis and expression in a heterologous host”, Chemistry and Biology 5, 647– 659.
   PubMed Web of Science ®Google Scholar
• Ichinose, K., Ozawa, M., Itou, K., Kunieda, K. and Ebizuka, Y. (2003) “Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochro- maneqionone gene clusters”, Microbiology 149, 1633– 1645.
   PubMed Web of Science ®Google Scholar
• Ikeda, H., Ishikawa, J., Hanamoto, A., Shinose, M., Kikuchi, H., Shiba, T., Sabaki, Y., Hattori, Y. and Omura, S. (2003) “Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis”, Nature Biotechnology 21, 526– 531.
   PubMed Web of Science ®Google Scholar
• Jornvall, H., Persson, B., Krook, M., Atrian, S., Gonzales-Duarte, R., Jeffery, J. and Ghosh, D. (1995) “Short-chain dehydro- genases/reductases (SDR)”, Biochemistry 34, 6003– 6013.
   PubMed Web of Science ®Google Scholar
• Kendrew, S.G., Harding, S.E., Hopwood, D.A. and Marsh, E.N.G. (1995) “Identification of a flavin: NADHoxidoreductase involved in the biosynthesis of actinorhodin”, Journal of Biological Chemistry 270, 17339– 17343.
   PubMed Web of Science ®Google Scholar
• Khosla, C., Gokhale, R.S., Jacobsen, J.R. and Cane, D.E. (1999) “Tolerance and specificity of polyketide synthases”, Annual Review of Biochemistry 68, 219– 253.
   PubMed Web of Science ®Google Scholar
• Kieser, T., Bibb, M.J., Buttner, M.J., Chater, K.F. and Hopwood, D.A. (2000) Practical Streptomyces genetics (The John Innes Foundation, Norwich).
   Google Scholar
• Kormanec, J., Rezuchova, B. and Farkasovsky, M. (1993) “Optimization of Streptomyces aureofaciens transformation and disruption of the hrdA gene encoding a homologue of the principal s factor”, Journal of General Microbiology 139, 2525– 2529.
   Google Scholar
• Kormanec, J., Sevcikova, B., Sprusansky, O., Benada, O., Kofronova, O., Novakova, R., Rezuchova, B., Potuckova, L. and Homerova, D. (1998) “The Streptomyces aureofaciens homologue of the whiB gene is essential for sporulation and its expression correlates with the developmental stage”, Folia Microbiologica 43, 605– 612.
   PubMed Web of Science ®Google Scholar
• Li, A. and Piel, J. (2002) “A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal poly- ketide griseorhodin A”, Chemistry and Biology 9, 1017 – 1026.
   PubMed Web of Science ®Google Scholar
• Lombo, F., Blanco, G., Fernandez, E., Mendez, C. and Salas, J.A. (1996) “Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin”, Gene 172, 87– 91.
   PubMed Web of Science ®Google Scholar
• Marti, T., Hu, Z., Pohl, N.L., Shah, A.N. and Khosla, C. (2000) “Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist”, J. Biol. Chem. 275, 33443– 33448.
   PubMed Web of Science ®Google Scholar
• Martinez-Costa, O.H., Martin-Triana, A.J., Martinez, E., Fernandez-Moreno, M.A. and Malpartida, F. (1999) “An additional regulatory gene for actinorhodin production in Streptomyces lividans involves a LysR-type transcriptional regulator”, Journal of Bacteriology 181, 4353– 4364.
   PubMed Web of Science ®Google Scholar
• Novakova, R., Bistakova, J., Homerova, D., Rezuchova, B. and Kormanec, J. (2002) “Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239”, Gene 297, 197– 208.
   PubMed Web of Science ®Google Scholar
• Waldron, C., Matsushima, P., Rosteck, P.R., Jr., Broughton, M.C., Turner, J., Madduri, K., Crawford, K.P., Merlo, D.J. and Baltz, R.H. (2001) “Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa”, Chemistry and Biology 8, 487– 499.
   PubMedGoogle Scholar
• Wang, L., White, R.L. and Vining, L.C. (2002) “Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone”, Microbiology 148, 1091– 1103.
   PubMed Web of Science ®Google Scholar
• Wright, F. and Bibb, M.J. (1992) “Codon usage in the G þ C rich Streptomyces genome”, Gene 113, 55– 65.
   PubMed Web of Science ®Google Scholar