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Research Article

Cloning and Characterization of a New Polyketide Synthase Gene Cluster in Streptomyces aureofaciens CCM 3239

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Pages 188-195 | Published online: 11 Jul 2009

References

  • Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.O., Seidman, J.S., Smith, J.A. and Struhl, K. (1995) Current Protocols in Molecular Biology (Wiley, New York).
  • Bentley, S.D., Chater, K.F., Cerdeno-Tarraga, A.M., Challis, G.L., Thomson, N.R., James, K.D., Harris, D.E., Quail, M.A., Kieser, H., Harper, D., Bateman, A., Brown, S., Chandra, G., Chen, C.W., Collins, M., Cronin, A., Fraser, A., Goble, A., Hidalgo, J., Hornsby, T., Howarth, S., Huang, C.H., Kieser, T., Larke, L., Murphy, L., Oliver, K., O’Neil, S., Rabbinowitsch, E., Rajandream, M.A., Rutherford, K., Rutter, S., Seeger, K., Saunders, D., Sharp, S., Squares, R., Squares, S., Taylor, K., Warren, T., Wietzorrek, A., Woodward, J., Barrell, B.G., Parkhill, J. and Hopwood, D.A. (2002) “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)”, Nature 417, 141– 147.
  • Bisang, C., Long, P.F., Cortes, J., Westcott, J., Crosby, J., Matharu, A-L., Cox, R.J., Simpson, T.J., Staunton, J. and Leadlay, P.F. (1999) “A chain initiation factor common to both modular and aromatic polyketide synthases”, Nature 401, 502– 505.
  • Brunker, P., McKinney, K., Sterner, O., Minas, W. and Bailey, J.E. (1999) “Isolation and characterization of the naphtocyclinone gene cluster from Streptomyces arenae DSM40737 and heterologous expression pf the polyketide synthase genes”, Gene 227, 125– 135.
  • Chater, K.F. (1998) “Taking a genetic scalpel to the Streptomyces colony”, Microbiology 144, 1465 – 1478.
  • Davis, N.K. and Chater, K.F. (1990) “Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to poly- ketide antibiotics”, Molecular Microbiology 4, 1679– 11691.
  • Decker, H. and Haag, S. (1995) “Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tu2717, which carries the genes fro biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation”, Journal of Bacteriology 177, 6126– 6136.
  • Grimm, A., Madduri, K., Ali, A. and Hutchinson, C.R. (1994) “Characterization of the Streptomyces peucetius ATCC2905 genes encoding doxorubicin polyketide synthase”, Gene 151, 1– 10.
  • Han, L., Yang, K., Ramalingam, E., Mosher, R.H. and Vining, L.C. (1994) “Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezualeae ISP5230”, Microbiology 140, 3379– 3389.
  • Hopwood, D.A. (1997) “Genetic contributions to understanding polyketide synthases”, Chemical Reviews 97, 2465– 2497.
  • Horinouchi, S., Hara, O. and Beppu, T. (1983) “Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans”, Journal of Bacterio- logy 155, 1238– 1248.
  • Hullo, M-F., Moszer, I., Danchin, A. and Marti-Verstraete, I. (2001) “CotA of Bacillus subtilis is a copper-dependent laccase”, Journal of Bacteriology 183, 5426– 5430.
  • Ichinose, K., Bedford, D.J., Tornus, D., Bechtohold, A., Bibb, M.J., Revill, W.P., Floss, H.G. and Hopwood, D.A. (1998) “The granaticin biosynthetic gene cluster of Streptomyces violaceor- uber Tu22: sequence analysis and expression in a heterologous host”, Chemistry and Biology 5, 647– 659.
  • Ichinose, K., Ozawa, M., Itou, K., Kunieda, K. and Ebizuka, Y. (2003) “Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochro- maneqionone gene clusters”, Microbiology 149, 1633– 1645.
  • Ikeda, H., Ishikawa, J., Hanamoto, A., Shinose, M., Kikuchi, H., Shiba, T., Sabaki, Y., Hattori, Y. and Omura, S. (2003) “Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis”, Nature Biotechnology 21, 526– 531.
  • Jornvall, H., Persson, B., Krook, M., Atrian, S., Gonzales-Duarte, R., Jeffery, J. and Ghosh, D. (1995) “Short-chain dehydro- genases/reductases (SDR)”, Biochemistry 34, 6003– 6013.
  • Kendrew, S.G., Harding, S.E., Hopwood, D.A. and Marsh, E.N.G. (1995) “Identification of a flavin: NADHoxidoreductase involved in the biosynthesis of actinorhodin”, Journal of Biological Chemistry 270, 17339– 17343.
  • Khosla, C., Gokhale, R.S., Jacobsen, J.R. and Cane, D.E. (1999) “Tolerance and specificity of polyketide synthases”, Annual Review of Biochemistry 68, 219– 253.
  • Kieser, T., Bibb, M.J., Buttner, M.J., Chater, K.F. and Hopwood, D.A. (2000) Practical Streptomyces genetics (The John Innes Foundation, Norwich).
  • Kormanec, J., Rezuchova, B. and Farkasovsky, M. (1993) “Optimization of Streptomyces aureofaciens transformation and disruption of the hrdA gene encoding a homologue of the principal s factor”, Journal of General Microbiology 139, 2525– 2529.
  • Kormanec, J., Sevcikova, B., Sprusansky, O., Benada, O., Kofronova, O., Novakova, R., Rezuchova, B., Potuckova, L. and Homerova, D. (1998) “The Streptomyces aureofaciens homologue of the whiB gene is essential for sporulation and its expression correlates with the developmental stage”, Folia Microbiologica 43, 605– 612.
  • Li, A. and Piel, J. (2002) “A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal poly- ketide griseorhodin A”, Chemistry and Biology 9, 1017 – 1026.
  • Lombo, F., Blanco, G., Fernandez, E., Mendez, C. and Salas, J.A. (1996) “Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin”, Gene 172, 87– 91.
  • Marti, T., Hu, Z., Pohl, N.L., Shah, A.N. and Khosla, C. (2000) “Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist”, J. Biol. Chem. 275, 33443– 33448.
  • Martinez-Costa, O.H., Martin-Triana, A.J., Martinez, E., Fernandez-Moreno, M.A. and Malpartida, F. (1999) “An additional regulatory gene for actinorhodin production in Streptomyces lividans involves a LysR-type transcriptional regulator”, Journal of Bacteriology 181, 4353– 4364.
  • Novakova, R., Bistakova, J., Homerova, D., Rezuchova, B. and Kormanec, J. (2002) “Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239”, Gene 297, 197– 208.
  • Waldron, C., Matsushima, P., Rosteck, P.R., Jr., Broughton, M.C., Turner, J., Madduri, K., Crawford, K.P., Merlo, D.J. and Baltz, R.H. (2001) “Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa”, Chemistry and Biology 8, 487– 499.
  • Wang, L., White, R.L. and Vining, L.C. (2002) “Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone”, Microbiology 148, 1091– 1103.
  • Wright, F. and Bibb, M.J. (1992) “Codon usage in the G þ C rich Streptomyces genome”, Gene 113, 55– 65.

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