Developments in the synthesis of new functionalized bisphosphonate drug candidates such as cyclic prodrugs

V. A. PavlovGirindus America Inc., Cincinnati, OH, USA;Campus Mundus LLC, Worcester, MA, USACorrespondence[email protected]

F. H. EbetinoBioVinc LLC, Pasadena, CA, USA;Chemistry Department, University of Rochester, Rochester, NY, USA

M. W. LundyBioVinc LLC, Pasadena, CA, USA

J. JolyPharma-GPS, Dayton, OH, USA

R. L. DobsonProcter & Gamble, Mason, OH, USA

R. G. G. RussellDepartment of Oncology and Metabolism, Medical School, University of Sheffield, UK

A. W. MazurGirindus America Inc., Cincinnati, OH, USA;TWI Chem LLC, Cincinnati, OH, USA

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References

Ebetino, F. H.; Hogan, A.-M. L.; Sun, S.; Tsoumpra, M. K.; Duan, X.; Triffitt, J. T.; Kwaasi, A. A.; Dunford, J. E.; Barnett, B. L.; Oppermann, U.; Lundy, M. W.; Boyde, A.; Kashemirov, B. A.; McKenna, C. E.; Russell, R. G. G. Bone. 2011, 49(1), 20-33.
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Ebetino, F. H.; Mazur, A. W.; Dobson, R. L. M. US Patent 0098251 A1, 2011.
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Pavlov, V. A.; Smith, J. A. S.; Zjablikova, T. A. Magn.Res.Chem. 1992, 30, 716.
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