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Leukemia & Lymphoma Volume 43, 2002 - Issue 12
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Research Article

Apoptosis Stimulating Protein of p53 (ASPP2) Expression Differs in Diffuse Large B-cell and Follicular Center Lymphoma: Correlation with Clinical Outcome

Izidore S. Lossos Division of Medical Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
,
Yasodha Natkunam Division of Pathology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
,
Ronald Levy Division of Medical Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
&
Charles D. Lopez Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, MC-L586B, Portland, OR 97201-3098, USA
Pages 2309-2317 | Published online: 01 Jul 2009

  • Ko, L. and Pieves, C. (1996) "p53: Puzzle and paradigm", Genes and Development 10, 1054-1072.
  • Levine, A. (1997) " P53, The cellular gatekepper for growth and division", Cell 88, 323-331.
  • Ford, J.M. and Hanawalt, P.C. (1997) "Role of DNA excision repair gene defects in the ethiology of cancer", Current Topics Microniology and Immunology 221, 47-70.
  • Ichikawa, A., Kinoshita, T., Watanabe, T., Kato, H., H., Nagai, H., Tsushita, K., Saito, H. and Hotta, T. (1997) "Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma". New England Journal of Medicine 337, 529- 534.
  • Koduru, P.R., Raju, K., Vadmal, V., Menezes, G., Shah, S., Susin, M., Kolitz, J. and Broome, J.D. (1997) "Correlation between mutation in p53, p53 expression, cylogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma", Blood 90, 4078-4091.
  • Gaidano, G., Ballerini, P., Gong, J.Z., Inghirami, G., Neri, k A., Newcomb, E., Macgrath, IT., Knowles, D.M. and Dalla-Favera, R. (1991) "p53 mutations in human lymphold malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia", Proceedings of the National Academy of Science USA 88, 5413-5417.
  • Lindstrom, M.S., Klangby, and Wiman, K.G. (2001) "p14ARF homozygous deletion or MDM2 overexpresssion in Burkitt lymphoma lines carrying wildtype p53", Oncogene 20, 2171-2177.
  • Barrans, S.L., Carter, I., Owen, R.G., Davies, F.E., Patmore, R.D., Haynes, A.P., Morgan, G.J. and Jack, A.S, (2002) "Germinal center phenotype and Bcl-2 expression combined with the International Prognostic Index improves patient risk stratification in diffuse large B-cell 1ymphoma", Blood 99, 1136-1143.
  • Tavor, S., Takeuchi, S., Tsukasaki, K., Miller, C.W., Said, J.W. and Koeffler, H.P (2001) "Analysis of the CHK2 gene in lymphoid malignancies", Leukemia and Lymphoma 42, 517-520.
  • Camacho, E., Hernandez, L., Hernandez, S., Tort, F., Bellosillo, B., Bea, S., Bosch, F., Montserrat, E., Cardesa, A., Fernandez, P.L. and Campo, E. (2002) "ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidytinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances", Blood 99, 238-244.
  • Stankovic, T., Stewart, G.S., Fegan, C., Biggs, P., Last. J., Byrd, P.J., Keenan, R.D., Moss, P.A. and Taylor, A.M. (2002) "Ataxia telangiectasia, mutated deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage". Blood 99, 300-309.
  • Kawaski, C., Ohshim, K., Suzumiya, J., Kanda, M., Tsuchiya, T., Tamura, K. and Kikuchi, M. (2001) "Rearrangements of Bcl-1, Bcl-2, Bcl-6, and c-Myc in diffuse B-cell lymphoma", Leukemia and Lymphoma, 42, 1099-1106.
  • Lossos, I., Jones, C.D., Warnke, R., Natkunam, Y., Kaizer, H., Zehnder, J.L., Tibshirani, R. and Levy, R. (2001) "Expression of a single gene. Bcl-6, Strongly predients survival in patients with diffuse large B-cell lymphoma", Blood 98, 945-951.
  • Adida, C, Haioun, C., Gaulard, P., Lepage, E., Morel, P., Briere, L., Dombert, H., Reyes, F., Diebold, J., Gisselbrechat, C., Salles, G., Altieri, D.C., and Molina, T.J. (2000) "Prognostic significance of survival expression in diffuse large B-cell lymphoma". Blood 96, 1921-1921.
  • Samuels-Lev, Y., O'Cunnor, D.J., Bergamaschi, D,. Trigiante, G., Hsieh, J.-K., Zhong, S., Campargue, I., Naumovski, L., Crook, T. and Lu, X, (2001). "ASPP proteins specifically Stimulate the apoptotic function of p53", Molecular cell 8, 781-794.
  • Lopez, C.D., Ao, Y., Rohde, L.H., Perez, T.D., O'Connor, D.J., Lu, X., Ford, J.M. and Naumovski, L. (2000) "Pro-apoptotic p53interacting protein 53BP2 is induced by UV irradiation but suppressed by P53", Molecular and Cellular Biology 20, 8018-8025.
  • Iwabuchi, K., Li. B., Massa, H.F., Trask, B.J., Takayasu, D. and Field, S. (1998) "Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2", The Journal of Biological Chemistry 273, 26061-26068.
  • Mori, T., Okamoto, H., Takahashi, N., Ueda, R. Okamoto, T. (2000) "Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines", FEBS Letters 465, 124-128.
  • Sgroi, D.C., Teng, S., Robinson, G., LeVangie, R., Hudson, J.R., and Elkahloun, A.G. (1999) "In vivo expression expression profile analysis of humun breast cancer progression" Cancer Research 59, 5656-5661.
  • Gendler, S.J., Cohen, E.P., Craston, A., Duhig, T., Johnstone, G. and Barnes, D. (1990) "The locus of the polymorphic epithelial mucin (PEM) tumour antigen chomosome 1q21 shows a high frequency of alteraliim in primary human breast tumours", International Journal of Cancer 45, 431-435.
  • Li, Y.S., Ramsay, D.A., S., F.Y., Armstrong, R.F. and Del Maestro, R.F (1995) "Cytogenede evidence that a tumor suppressor gene in the long arm of chromosome 1 contributes to glioma growth", Cancer Genetics and Cytogenetics 84, 46-50.
  • Muity, V.V., Li, R.G., Mathew, S., Reuter, V.E., L., B.D., Bosl, G.J. and Chaganti, R.S. (1994) "Replication error-type genetic instability at 1q42-43 in human male germ cell tumors", Cancer Research 54, 3981-3985.
  • Haglund, U., Juliusson, G., Stellan, B. and Gahrton, G. (1994) "Hairy cell leukemia is characterized by clonal chromosome abnormalities clustered to specific regions", Blood 83, 2637-2645.
  • Mertens, F., Mandahl, N., Orndal, C., Baldetorp, B., Bauer, H.C., Rydholm, A., Weibe, T., Willen, H., Akerman, M. and Heim, S. (1993) "Cutpgemetoc findings in 33 osteosarcomas", International Journal of Cancer 55, 44-50.
  • Schlegelberger, B., Zwingers, T., Harder, L., Nowotny, H., Siebert, R., Vesely, M., Bartels, H., Sonnen, R., Hopfinger, G., Nader, A., Ott. G., Muller-Hermelink, K., Feller, A. and Heinz, R. (1999) "Clinicopathogenetic significance of chromosomal abnormalities in patients with blastic peripheral B-cell lymphoma", Blood 94, 3114-3120.
  • Alizadeh, A, Eisen, M., Davis, R., Ma C., Lossos, I., Rossenwald, A., Boldrick, J., H., Tran, T., Yo, X., Powell, J., Yang, L., Marti, G., Moore, T., Hudson, J.R., Lu, L., Lewis, D., Tibshirani, R., Sherlock, G., Chan, W., Greiner, T., Weisenburger, D., Arimitage, J.O., Warnke, R., Levy, R., Wilson, W., Grever, M., Byrd, J.C., Botstein, D., Brown, P. and Staudt, L.M. (2000) "Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling". Nature 403, 503-511.
  • Cabanillas, F., Horning, S., Kaminski, M. and Champlin, R. (2000) "Managing indolent lymphomas in relapse: working our way through A plethora of options". Hematology (American Society of Hematology Educational Program), 166-179.
  • Multani, P., White, C.A. and Griilo-Lopez, A. (2001) "NonHodgkin's lymphoma; a review of conventional treatments", Current Pharmacology and Biotechnology 2, 279-291.
  • Rosenbeig, S.A. (1985) "Karnofsky memorial lecture. The lowgrade non-Hodgkin's lymphomas: challenges and opportunities", Journal of Clinical Oncology 3, 299-310.
  • Shipp, M., Harris, N. and Mauch, P. (1997) "The non-Hodgkin's lymphomas". In: DeVita, V.T., Hellman, S. and Rosenberg, S.A., eds, Cancer Principles and Practices, of Oncology (Lippincott, Philadelphia), pp 2165-2220.
  • Harris, N., Jaffe, E.S., Stein, H., Banks, P.M., Chan, J.K,. Cleary, ML., Delsol, G., De Wolf-Peelers., C,. Falini, B. and Gatter, K.C. (1994) "A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group (see comments)". Blood, 1361-1392.
  • (1997) "A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphonw: the nonHodgkin's lymphoma classiticaiion project", Blood 89, 3909-3918.
  • (1993) "A predictive model for aggressive non-Hodgkin's lymphoma: the international non-Hodgkin's lymphoma prognostic factors project". New England Journal of Medicine 329, 987-994.
  • Ford, J.M. and Hanawalt, P.C. (1997) "Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated hitman fibroblasts", The Journal of Biological Chemistry 272, 28073-28080.
  • Bindl, J.M. and Warnke, R.A. (1986) "Advantages of detecting monoclonal antihody binding to tissue sections with biotin and avidin reagents in coplin jars", American Journal of Clinical Pathology 85, 490-493.
  • Ao, Y., Rohde, L.H. and Naumovski, L. (2001) "p53-Interacting protein 53BP2 inhibits clonogenic survival and sensitizes cells to doxorubicin but not paclitaxel-induced apotosis", Oncogene 20, 2720-2725.
  • Kramer, M.H., Hermans, J., Parker, J., Krol, A.D., Kluin-Nelemans, J.C., Haak, H.L., van Groningen, K., van Krieken, J.H., de Jong, D. and Kluin, P.M. (1996) "Clinical significance of Bcl-2 and p53 protein expression in diffuse large B-cell lymphoma: a populationbased study", Journal of Clinical Oncology 14, 2131-2138.
  • Naumovski, L. and Cleary, M.L. (1996) "The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M", Molecular and Cellular Biology 16,. 3884-3892.
  • Yang, J., Hori, M., Takahashi, N., Kawabe, T., Kato, H. and Okamoto, T. (1999) "NF-kB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2". Oncogene 18, 5177-5186.
  • Nakagawo, H., Koyama, K., Murata, Y., Murito, M., Akiyanw, T. and Nakamura, Y, (2000) "APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocales it to the perinucleus", Cancer Research 60, 101-105.
  • Helps., N., Barker, H., Elledge, S.J. and Cohen, P. (1995) "Protein phosphamse 1 interacts with p53BP2. a protein which binds to the tumour suppressor p53". FEBS Letters 377, 295-300.
  • Jenkins, R.B., Bartelt, D.J., Stalboerger, P., Persons, D., Dahl. R.J., Podralz, K., Keeney, G. and Hartmann, L. (1993) "Cytogenetic studies of epithelial ovarian carcinomas". Canter Genetics and Cytogenetics 71, 76-86.
  • Hedenfalk, M.S., Duggan, D., Chen, Y., Radmucher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O., Willbnd, B., Borg, A. and Trent, J. (2001) "Gene-expression profiles in hereditary breast cancer". New England Journal of Medicine 344, 539-548.
  • Pomeroy, S., Tamayu, P., Gaasenbeek, M, Sturia, L.M., Angelo, M. McLaughlin, M., Kim, J., Goumnerova, L., Black, P., Lau, C., Allen, J., Zagsag. D., Oison. J., Curran. T., Wetmore, C., Biegel, J., Poggio, T., Mukherjee. S., Riftin, R., Calitano, A., Stolovitsky, G., Louis, D., Mesirov, J., Lander, E. and Golub, T. (2002) "Prediction of central nervous system embryonal tumour outcome based on gene expression". Nature 415, 436-442.

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