79
Views
16
CrossRef citations to date
0
Altmetric
Research Article

Differential Expression of Human Equilibrative Nucleoside Transporter 1 (hENT1) Protein in the Reed-Sternberg Cells of Hodgkin's Disease

, , , , , , , , & show all
Pages 1435-1440 | Published online: 01 Jul 2009

  • Zinzani, P.L., et al., (2000) "Value of gemcitabine treatment in heavily pretreated Hodgkin's disease patients", Haematologica 85 (9), 926 - 929
  • Santoro, A., et al., (2000) "Gemcitabine in the treatment of refractory Hodgkin's disease: results of a multicenter phase II study", J. Clin. Oncol. 18 (13), 2615 - 2619
  • Abbruzzese, J.L. (1996) "Phase I studies with the novel nucleoside analog gemcitabine", Semin. Oncol. 23 (5 Suppl. 10), 25 - 31
  • Plunkett, W., et al., (1995) "Gemcitabine: metabolism, mechanisms of action, and self-potentiation", Semin. Oncol. 22 (4 Suppl. 11), 3 - 10
  • A.P. Association, Solimando, D.A., et al. (1999) Drug Information Handbook for Oncology (Lexi-Comp, Hudson, Cleveland, OH)
  • Vickers, M.F., et al., (2000) "Nucleoside transporter proteins: emerging targets for drug discovery", Emerg. Ther. Targets 4 (4), 515 - 539
  • Cass, C.E., et al., (1999) "Nucleoside transporters of mammalian cells", Pharm. Biotechnol. 12, 313 - 352
  • Baldwin, S.A., et al., (1999) "Nucleoside transporters: molecular biology and implications for therapeutic development", Mol. Med. Today 5 (5), 216 - 224
  • Mackey, J.R., et al., (1998) "The role of nucleoside transport in anticancer drug resistance", Drug Resist. Updates 1 (5), 310 - 324
  • Mackey, J.R., et al., (1998) "Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines", Cancer Res. 58, 4349 - 4357
  • Janowska-Wieczorek, A., et al., (1999) "Gemcitabine membrane transport capabilities of normal human hematopoietic progenitor (CD34+) cells", Blood 94 (10), 279a
  • Mackey, J.R., et al., (2002) "Immunohistochemical variation of human equilibrative nucleoside transporter 1 (hENT1) protein in primary breast cancers", Clin. Cancer Res., 8, 110 - 116
  • Cass, C.E., Muzik, H. and Paterson, A.R. (1975) "Combination therapy of mouse leukemia L1210 by 1-beta- d -arabinofuranosylcytosine and 6-[(4-nitrobenzyl)thio]-9-beta- d -ribofuranosylpurine", Cancer Res. 35 (5), 1187 - 1193
  • Cass, C.E., et al., (1981) "Absence of binding sites for the transport inhibitor nitrobenzylthioinosine on nucleoside transport-deficient mouse lymphoma cells", Biochim. Biophys. Acta 649 (3), 769 - 777
  • Cass, C.E., et al., (1992) "A comparison of the abilities of nitrobenzylthioinosine, dilazep, and dipyridamole to protect human hematopoietic cells from 7-deazaadenosine (tubercidin)", Cancer Res. 52 (21), 5879 - 5886
  • Paterson, A.R., et al., (1979) "Low specificity of the nucleoside transport mechanism of RPMI 6410 cells", Mol. Pharmacol. 16 (3), 900 - 908
  • Wiley, J.S., Jones, S.P. and Sawyer, W.H. (1983) "Cytosine arabinoside transport by human leukaemic cells", Eur. J. Cancer Clin. Oncol. 19 (8), 1067 - 1074
  • Wiley, J.S., et al., (1982) "Cytosine arabinoside influx and nucleoside transport sites in acute leukemia", J. Clin. Invest. 69 (2), 479 - 489
  • Gati, W.P., et al., (1998) "Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (arac)", Leuk. Lymph. 32, 45 - 54
  • Gati, W.P., et al., (1997) "Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein", Blood 90 (1), 346 - 353
  • Wiley, J.S., et al., (1985) "Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma", J. Clin. Invest. 75 (2), 632 - 642
  • Jennings, L.L., et al., (2001) "Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system", Neuropharmacology 40, 722 - 731
  • Lister, T.A., et al., (1989) "Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting", J. Clin. Oncol. 7 (11), 1630 - 1636
  • Murray, P.G., et al., (1999) "Effect of Epstein-Barr virus infection on response to chemotherapy and survival in Hodgkin's disease", Blood 94 (2), 442 - 447
  • Jarrett, A.F., Armstrong, A.A. and Alexander, E. (1996) "Epidemiology of EBV and Hodgkin's lymphoma", Ann. Oncol. 7 (Suppl. 4), 5 - 10
  • Santoro, A., et al., (1997) "Phase II study with gemcitabine in pretreated patients with Hodgkin's (HD) and non-Hodgkin's lymphomas (NHL): results of a multicenter study", Proc. Annu. Meet. Am. Soc. Clin. Oncol. 16, A71
  • Hanel, M., et al., (2001) "Salvage chemotherapy with mitoxantrone, fludarabine, cytarabine, and cisplatin (MIFAP) in relapsing and refractory lymphoma", J. Cancer Res. Clin. Oncol. 127 (6), 387 - 395
  • Betticher, D.C., et al., (1994) "High incidence of infections after 2-chlorodeoxyadenosine (2-CDA) therapy in patients with malignant lymphomas and chronic and acute leukaemias", Ann. Oncol. 5 (1), 57 - 64
  • Cummings, F.J., et al., (1991) "Phase II trial of pentostatin in refractory lymphomas and cutaneous T-cell disease", J. Clin. Oncol. 9 (4), 565 - 571
  • Martin, A., et al., (2001) "Long-term follow-up in patients treated with Mini-BEAM as salvage therapy for relapsed or refractory Hodgkin's disease", Br. J. Haematol. 113 (1), 161 - 171
  • Diehl, V., Mauch, P.M. and Harris, N.L. (2000) "Hodgkin's disease. Chapter 45.6", In: DeVita, V.T., Hellmann, S. and Rosenberg, S.A., eds, Cancer: Principles and Practice of Oncology (Lippincott Williams and Wilkins, Philadelphia, PA), pp 2339 - 2387
  • Thomas, J., et al., (1992) "Phase II study of cytarabine in Hodgkin's disease. The EORTC Lymphoma Cooperative Group", Eur. J. Cancer, 857 - 859
  • Wiley, J.S., Smith, C.L. and Jamieson, G.P. (1991) "Transport of 2′-deoxycoformycin in human leukemic and lymphoma cells", Biochem. Pharmacol. 42 (3), 708 - 710
  • Kaplinsky, C., et al., (1986) "Selective protection of tubercidin toxicity by nitrobenzyl thioinosine in normal tissues but not in human neuroblastoma cells", Cancer Chemother. Pharmacol. 17 (3), 264 - 268
  • Boumah, C.E., Hogue, D.L. and Cass, C.E. (1992) "Expression of high levels of nitrobenzylthioinosine-sensitive nucleoside transport in cultured human choriocarcinoma (BeWo) cells", Biochem. J. 288 (Pt 3), 987 - 996
  • Pressacco, J., et al., (1995) "Modulation of the equilibrative nucleoside transporter by inhibitors of DNA synthesis", Br. J. Cancer 72 (4), 939 - 942
  • Cass, C.E., et al., (1979) "Fluctuations in nucleoside uptake and binding of the inhibitor of nucleoside transport, nitrobenzylthioinosine, during the replication cycle of HeLa cells", Cancer Res. 39 (4), 1245 - 1252
  • Wiley, J.S., et al., (1994) "Assessment of proliferative responses to granulocyte-macrophage colony-stimulating factor (GM-CSF) in acute myeloid leukaemia using a fluorescent ligand for the nucleoside transporter", Leukemia 8 (1), 181 - 185
  • Smith, C.L., et al., (1989) "Nucleoside transport and proliferative rate in human thymocytes and lymphocytes", Blood 74 (6), 2038 - 2042
  • Goh, L.B., Mack, P. and Lee, C.W. (1995) "Nitrobenzylthioinosine-binding protein overexpression in human breast, liver, stomach and colorectal tumour tissues", Anticancer Res. 15 (6B), 2575 - 2579
  • Fung, M.C., et al., (1999) "A review of hemolytic uremic syndrome in patients treated with gemcitabine therapy", Cancer 85 (9), 2023 - 2032
  • Dumontet, C., et al., (2001) "Gemcitabine as a single agent in the treatment of relapsed or refractory low-grade non-Hodgkin's lymphoma", Br. J. Haematol. 113 (3), 772 - 778
  • Pavlakis, N., et al., (1997) "Fatal pulmonary toxicity resulting from treatment with gemcitabine", Cancer 80 (2), 286 - 291
  • Gietema, J.A., et al., (1998) "Effects of gemcitabine on renal function in patients with non-small cell lung cancer", Eur. J. Cancer 34 (1), 199 - 202
  • Fracasso, P.M., et al., (1999) "Membranoproliferative glomerulonephritis following gemcitabine and vinorelbine chemotherapy for peritoneal mesothelioma", J. Natl Cancer Inst. 91 (20), 1779 - 1780
  • Bruns, C.J., et al., (2000) "Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms", Clin. Cancer Res. 6 (5), 1936 - 1948
  • Trumper, L.H., et al., (1993) "Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations", Blood 81 (11), 3097 - 3115
  • Kuppers, R., et al., (1994) "Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development", Proc. Natl Acad. Sci. USA 91 (23), 10962 - 10966
  • Kanzler, H., et al., (1996) "Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells", J. Exp. Med. 184 (4), 1495 - 1505
  • Jox, A., et al., (1998) "Detection of identical Hodgkin-Reed-Sternberg cell specific immunoglobulin gene rearrangements in a patient with Hodgkin's disease of mixed cellularity subtype at primary diagnosis and in relapse two and a half years later", Ann. Oncol. 9 (3), 283 - 287
  • Hasenclever, D. and Diehl, V. (1998) "A prognostic score for advanced Hodgkin's disease. International prognostic factors project on advanced Hodgkin's disease", N. Engl. J. Med. 339 (21), 1506 - 1514

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.