- Strand, S., Hofmann. W.J., Hug, H., Muller. M., Olio. G., Strand, D., Mariani, S.M., Stremmel, W., Krammer. P.H. and Galle, P.R. (1996) "Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligandexpressing tumor cells-a mechanism of immune evasion?". Nature Medicine 2, 1361-1366.
- Hahnc, M. Rimoldi. D., Schroter. M., Romero, P., Schreier. M., French. L.E., Schneider. P., Bornand. T., Fontana. A., Lienard. D., Ccrottini. J. and Tschopp, J. (1996) "Melanoma cell expression of Fas(Apo-l/CD95) ligand: implications for tumor immune escape". Science 274. 136.V1366.
- Moller, P., Koretz, K., Leilhauser. F., Bruderlein. S., Henne. C-. Quentmeier. A. and Krammer, P.H. (1994) "Expression of APO-I (CD95). a member of the NGF/TNF receptor supcrfamily. in normal and neoplastic colon epithelium", intemotional Journal of Cancer 57,371-377.
- Lebel, M., Bertrand, R. and Mes-Masson, A.M. (1996) "Decreased Fas antigen receptor expression in testiculartumorcell lines derived from polyomavirus large T-antigen transgenie mice". Oncogene 12. 1127-1135.
- Tamiya, S., Etoh, K., Suzushima, H. Tijkatsuki, K. and Matsuoka, M. (1998) "Mutation of CD95 (Kas/Apo-l) gene in adult T-ceII leukemia cells". Blood 91. 3935 3942.
- Fenton, R.G., Hixon. J.A., Wright, P.W., Brooks, A.D. and Sayers, T.J. (1998) "Inhibition of has (CD95) expression and Fas-mediated apoptosis by oncogenic Ras". Cancer Research 58. 3391 -3400.
- PeIi. J., Schroter. M., Rudaz. C., Hahne, M., Meyer, C., Reichmann. E. and Tschopp, J. (1999) "Oncogenic Ras inhibits Fas ligandmediated apoptosis by downregulating the expression of Fas". EMBO Journal 18, 1824-1831.
- Macara, I.G., Lounsbury, K.M., Richards, S.A., McKieman. C. and Bar-Sap, D. (1996) "The Ras superfamily of GTPases". FASEB Journal 10, 625-630.
- Khosravi-Far, R, Campbell, S., Rossman, K.L. and Der, C.J. (1998) "Increasing complexity of Ras signal iransduction; involvement of Rho family proteins", Advances in Cancer Research 72, 57-107.
- Strzadala, L., Miazek. A., Matuszyk, J. and Kisielow. P. (1997) "Rote of thymic selection in the development of ihyruk lympbomas in TCR transgcnic mice". International Immunology 9, 127-138.
- Kobzdej, M., Matuszyk, J. and Strzadala, L. (2000) "Overexpression of Ras, Raf and L-myc but not Bcl-2 family proteins is linked with resistance to TCR-mcdiated apoptosis and tumorigencsis in thymic lymphomas from TCR lransgenic mice", Leukemia Research 24. 33-38.
- Dhanasekaran. N. and Reddy. E.P. (1998) "Signaling by dual specificity kinases", Oncngene 17. 1447-1455.
- Matuszyk, J., Kobzdej. M., Ziolo. E., Kalas. W., Kisielow, P. and Strzadala, L. (1998) "ITiymic lymphomas arc resistant to Nur77mediated apopiosis", Biochemical and Biophysical Research Communications 249, 279 282.
- Kisielow, R, Bluthmann. U., Staerz, U.D., Steinmetz. M. and von Boehiuer. H. (1988) "Tolerance in T-cell-receptor lransgcnic mice involves deletion of nonmature CD4 + 8 + thyrombocytes, Nature 333. 742-746.
- Beere, H.M., Chresta, C.M., Alejo-Herberg, A., Skladanowski. A., Dive, C., Larsen. A.K. and Hickman. J.A. (1995) "Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apopiosis", Molecular Pharmacology 47. 986-996
- Smith, P., Krohn. R., Hermanson. G., Mallia. A., Gartner. F., Provenzano, M., Fujimoto, E., Goeke. N, Olson. B. and Klenk, D. (1985) "Measurement of protein using bicinchoniflic acid". Analytical Biochemistry 150, 76-85.
- Laemmli. U.K. (1970) "Cleavage of structural proteins during the assembly of the head of bacteriophage T4". Nature 227. 680-685.
- Towbin, H. Staehelin, T. and Gordon, J. (1979) "Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications". Proceedings of the National Academy of Sciences of the United States of America 76. 4350-4354.
- Nicolelli. L., Migliorati. G., Pagliacci. M., Grignani. F. and Ricardi. C. (1991) "A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytomelry". Journal of lmmunological Methods 139, 271 -279.
- Ahn. N.G., Nahreini. T.S., Tolwinski. M.S. and Resing, K.A. (2001) "Pharmacologic inhibitors of MKKl and MKK2". Methods in Enzymolagy 332. 417-431.
- Sugawara, T. Moriguchi. T., Nishida, E. and Takahama. Y. (1998) "Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes". Immunity 9, 565 574.
- Jucinto, K., Werlen, G. and Karin, M. (1998) "Cooperation between Syk and Racl leads to synergistic JNK activation in T lymphocytes", lmmunily 8, 31 -41.
- Zimmermann, S. and Moelling, K. (1999) "Phosphorylation and regulation of Raf by Akt (protein kinase B)". Science 286, 1741-1744.
- Van Weering, D.H., Dc Rooij, J., Marte. B.M., Downward. J., Bos. J.I., and Burgering, B.M. (1998) "Protein kinase B activation and lamcllipodium formation are independent phosphoinosilide 3kinase-mediated events differentially regulated by endogenous Ras". Molecular and Cellular Biology 18, 18002 180011.
- Genot, E., Reif. K. Beach. S., Kramer. I. and Cantrell. D.A. (1998) "p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes", Oncogene 17, 1731- 1738.
- Lin K. and Abraham, K.M. (1997) 'Targets of p56(lck) activity in immature thymoblasts: stimulation of the Rax/Raf/MAPK pathway", International lmmunntogy 9, 291-303.
- Matuszyk. J., Cebrat. M., Kalas. W. and Strzadala. L. (2002) "HA1004. an inhibitor of serinc/threoninc protein kinases. restores the sensitivity of thymic lymphomas to Ca2+mediated apoptosis through a protein kinase A-independent mechanism". International Iminunopharmacology, 221, 435-442.
Inhibition of MEK Induces Fas Expression and Apoptosis in Lymphomas Overexpressing Ras
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.