- Hardy, R.R. and Hayakawa, K. (2001) "B cell development pathways", Annual Review of Immunology 19, 595-621.
- Hardy, R.R., Carmack, C.E., Shinton, S.A., Kemp, J.D. and Hayakawa, K. (1991) "Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow", Journal of Experimental Medicine 173, 1213-1225.
- Bowman, E.P., Campbell, J.J., Soler, D., Dong, Z., Manlongat, N., Picarella, D., Hardy, R.R. and Butcher, E.C. (2000) "Developmental switches in chemokine response profiles during B cell differentiation and maturation", Journal of Experimental Medicine 191, 1303-1318.
- Opstellen, D. and Osmond, D.O. (1985) "Regulation of pre-B cell proliferation in bone marrow: immunofluorescence stathmokinetic studies of cytoplasmic mu chain-bearing cells in anti-IgM-treated mice, hematologically deficient mutant mice and mice given sheep red blood cells". Eurupean Journal of Immunology 15, 599-605.
- Forster, I., Vieira, P. and Rajewsky, K. (1989) "Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse". International Immunology 1, 321-331.
- Allman, D.M., Ferguson, S.E., Lentz, V.M. and Cancro, M.P. (1993) "Peripheral B cell maturation. II. Heat-stable anligen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells". Journal of Immunology 151, 4431-4444.
- Goodnow, C.C., Crosbic, J., Adelstein, S., Lavoie, T.B., Smith-Gill, S.J., Brink, R.A., Pritchard-Briscoe, H., Wotherspoon, J.S., Loblay, R.H., Raphael, K., Trent, R.J. and Basten, A. (1988) "Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice". Nature 334, 676-682.
- Nemazee, D.A. and Burki, K. (1989) "Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class 1 antibody genes", Nature 337, 562-566.
- Brezinschek, H.P., Brezinschek, R.I. and Lipsky, P.E. (1995) "Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction", Journal of Immunology 155, 190-202.
- Melamed, D. and Nemazee, D. (1997) "Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest", Proceedings of the National Academy of Sciences USA 94, 9267-9272.
- Levine, M.H., Haberman, A.M., Sant Angelo, D.B., Hannum, L.G., Cancro, M.P., Janeway, Jr. C.A. and Shlomchik, M.J. (2000) "A B-cell receptor-specific selection step governs immature to mature B cell differentiation", Proceedings of the National Academy of Sciences USA 97, 2743-2748.
- Wellmann, U., Werner, A. and Winkler, T.H. (2001) "Altered selection processes of B lymphocytes in autoimmune NZB/W mice, despite intact central tolerance against DNA". European Journal of Immunology 31, 2800-2810.
- Xu, J., Foy, T.M., Laman, J.D., Elliott, E.A., Dunn, J.J., Waldschmidt, T.J., Elsemore, J., Noelle, R.J. and Flavell, R.A. (1994) "Mice deficient for the CD40 ligand", Immunity 1, 423-431.
- Cyster, J.G., Healy, J.I., Kishihara, K., Mak, T.W., Thomas, M.L. and Goodnow, C.C. (1996) "Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45". Nature 381, 325-328.
- Moore, P.A., Belvedere, O., Orr, A., Fieri, K., LaFleur, D.W., Feng, P., Soppet, D., Charters, M., Gentz, R., Parmelee, D., Li, Y., Galperina, O., Giri, J., Roschke, V., Nardelli, B., Carrell, J., Sosnovtseva, S., Greenfield, W., Ruben, S.M., Olsen, H.S., Fikes, J. and Hilbert, D.M. (1999) "BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator", Science 285, 260-263.
- Schneider, P., MacKay, F., Steiner, V., Hofman, K., Bodmer, J.-L., Holler, N., Ambrose, C., Lawton, P., Bixler, S., Acha-Orbea, H., Valmori, D., Romero, P., Werner-Favre, C., Zubler, R.H., Browning, J. and Tschopp, J. (1999) "BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth", Journal of Experimental Medicine 189, 1747-1756.
- Shu, H.-B., Hu, W.-H. and Johoson, H. (1999) "TALL-1 is a novel member of the TNF family that is down-regulated by milogens", Journal of Leukococyte Biology 65, 680-683.
- Tribouley, C., Wallroth, M., Chan, V., Paliard, X., Fang, E., Lamson, G., Pot, D., Escobedo, J. and Williams, L.T. (1999) "Characterization of a new member of the TNF family expressed on antigen presenting cells", Biological Chemistry 380, 1443-1447.
- Mukhopadhyay, A., Ni. J., Zhai, Y., Yu, G.-L. and Aggarwal, B.B. (1999) "Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-KB and c-Jun NH2-terminal kinase". Journal of Biological Chemistry 274, 15978-15981.
- Nardelli, B., Belvedere, O., Roschke, V. Moore, P.A., Olsen, H.S., Migone, T.S., Sosnovtseva, S., Carrell, J.A., Feng, P. Giri, J.G. and Hubert, D.M. (2001) "Synthesis and release of B-Lymphocyte stimulator from mycloid cells". Blood 97, 198-204.
- Locksley, R.M., Killeen, N. and Lenardo, M.J. (2001) "The TNF and TNF receptor superfamilies: integrating mammalian biology", Cell 104, 487-501.
- Gross, J.A., Johnston, J., Mudri, S., Enselman, R., Dillon, S.R., Madden, K., Xu, W., Parish-Novak, J., Foster, D., Lofton-Day, C. Moore, M., Littau, A., Grossman, A., Haugen, H., Foley, K., Blumberg, H., Harrison, K., Kindsvogel, W. and Clegg, C.H. (2000) "TACl and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease". Nature 404, 995-999.
- Thompson, J.S., Schneider, P., Kalled, S.L., Wang, L., Lefreve, E.A., Cachero, T.G., MacKay, F., Bixler, S.A., Zafari, M., Liu, Z.-Y., Woodcock, S.A., Qian, F., Batten, M., Madry, C., Richard, Y., Benjamin, C.D., Browining, J.L., Tsapis, A., Tschopp, J. and Ambrose, C. (2000) ''BAFF binds to (he tumor necrosis factor receptor-like molecule B Cell maturation antigen and it important for maintaining the peripheral B cell population". Journal of Experimental Medicine 192, 129-135.
- Xia, X.-Z., Treanor, J., Senaldi, G., Khare, S.D., Boone, T. Kelley, M., Theill, L.E., Colombero, A., Solovyev, I., Lee, F., McCabe, S., Elliott, R., Miner, K., Hawkins, N., Guo, J., Stolina, M., Yu, G. Wang, J., Delaney, J., Meng, S.-Y., Boyle, W.J. and Hsu, H. (2000) 'TACl is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation". Journal of Experimental Medicine 192, 137-143.
- Yan, M., Marsters, S.A., Grewal, I.S., Wang, H., Ashkenazi, A. and Dixit, V.M. (2000) "Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity". Nature Immunology 1, 37-41.
- Shu, H.-B. and Johnson, H. (2000) "B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1". Proceedings of the National Academy of Sciences USA 97. 9156-9161.
- Wu, Y., Bressette, D., Carrell, J.A., Kaufman, T. Feng, P., Taylor, K., Gan, Y. Cho, Y.H., Garcia. A., Gollatz, K., Dimke, D., LaFleur, D., Migone, T.S., Nardelli, B., Wei, P., Ruben, S.M., Ulrich, S.J., Olsen, H.S., Kanakaraj, P., Moore, P.A. and Baker, K.P. (2000) "Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS", Journal of Biological Chemistry 275, 35478-35485.
- Marsters, S.A., Yan, M., Pitti, R.M., Haas, P.E., Dixit, V.M. and Ashkenazi, A. (2000) "Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI". Current Biology 10, 785-788.
- Thompson, J.S., Bixler, S.A., Qian, F., Vora, K., Scott, M.L., Cachero, T.G., Hession, C., Schneider, P., Sizing, I.D., Mullen, C., Strauch, K., Zafari, M., Benjamin, C.D., Tschopp, J., Browning, J.L. and Ambrose, C. (2001) "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF', Science 293, 2108-2111.
- Yan, M., Brady, J.R., Chan, B., Lee, W.P., Hsu, B., Harless, S., Cancro, M., Grewal, I.S. and Dixit, V.M. (2001) "Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with sever B cell deficiency", Current Biology 11, 1547-1552.
- Ware, C.F., Santee, S. and Glass, A. (1998) "Tumor necrosis factor-related ligands and receptors", In: Thompson, A., ed. The Cytokine Handbook, pp 549-592.
- Kanakaraj, P., Migone, T.S., Nardelli, B., Ullrich, S., Li, Y., Olsen, H.S., Salcedo, T.W., Kaufman, T. Cochrane, E., Gan, Y., Hilbert, D.M. and Giri, J. (2001) "BLyS binds to B cells with high affinity and induces activation of the transcription factors NF-kB and ELF-1", Cytokine 13, 25-31.
- Von Bulow, G.-U. and Bram, R.J. (1997) "NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor family receptor superfamily", Science 278, 138-141.
- Wuang, H., Marsters, S.A., Baker, T., Chan, B., Lee, W.P., Fu, L., Tumas, D., Yan, M., Dixit, V.M., Ashkenazi, A. and Grewal, I.S. (2001) "TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice", Nature Immunology 7, 632-637.
- Laabi, Y., Gras, M.P., Brouet, J.C., Berger, R., Larsen, C.J. and Tsapis, A. (1994) "The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed". Nucleic Acids Research 22, 1147-1154.
- Hatzoglou, A., Roussel, J., Bourgeade, M.-F., Regier, E., Madry, C., Inoue, J., Devegne, O. and Tsapis, A. (2000) "TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1. TRAF2, and TRAF3 and activates NF-kB, ELK-1, c-Jun N-terminal kinase. and p38 mitogen-activated protein kinase", Journal of Immunology 165, 1322-1330.
- Rennert, P., Schneider, P., Cachero, T.G., Thompson, J., Trabach, L., Hertig, S., Holler, N., Qian, F., Mullen, C. Strauch, K., Browning, J.L., Ambrose, C. and Tschopp, J. (2000) "A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth". Journal of Experimental Medicine 192, 1677-1683.
- von Bulow, G.-U., van Deursen, J.M. and Bram, R.J. (2001) "Regulation of the T-independent humoral response by TACP'. Immunity 14, 573-582.
- Yan, M., Wang, H., Chan, B., Roose-Girma, M., Erickson, S., Baker, T., Tumas, D., Grewal, I.S. and Dixit, V.M. (2001) "Activation and accumulation of B cells in TACl-deficient mice". Nature Immunology 2, 638-643.
- Xu, S. and Lam, K.P. (2001) "B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses", Molecular and Cellular Biology 21, 4067-4074.
- Do, R.K.G., Hatada, E., Lee, H., Tourigny, M.R., Hilbert, D. and Chen-Kiang, S. (2000) "Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response". Journal of Experimental Medicine 192, 953-964.
- Batten, M., Groom, J., Cachero, T.G., Qian, F., Schneider, P., Tschopp, J., Browning, J.L. and Mackay, F. (2000) "BAFF mediates survival of peripheral immature B lymphocytes". Journal of Experimental Medicine 192, 1453-1465.
- Gross, J.A., Dillon, S.R., Mudri, S., Johnston, J., Littau. A., Roque, R., Rixon, M., Schou, O., Foley, K.P., Haugen, H., McMillen, S., Waggie, K., Schreckhise, R.W., Shoemaker, K., Vu, T., Moore, M., Grossman, A. and Clegg, C.H. (2001) "TACl-Ig neutralizes molecules critical for B cell development and autoimmunity disease: impaired B cell maturation in mice lacking BLyS". Immunity 15, 289-302.
- Schiemann, B., Gommerman, J.L., Vora, K., Cachero, T.G., Shulga-Morskaya Dobles, M., Frew, E. and Scott, M.L. (2001) "An essential role for BAFF in the normal development of B cells through a BCMA-indepcndent pathway". Science 293, 2111-2114.
- Mackay, F., Woodcock, S.A., Lawton, P., Ambrose, C., Baetscher, M., Schneider, P., Tschopp, J. and Browning, J.L. (1999) "Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations", Journal of Experimental Medicine 190, 1697-1710.
- Khare, S.D., Sarosi, I., Xia, X.-Z., McCabe, S, Miner, K., Solovyev, I., Hawkins, N., Kelley, M., Chang, D., Van, G., Ross, L., Delaney, J., Wang, L., Lacey, D., Boyle, W.J. and Hsu, H. (2000) "Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice", Proceedings of the National Academy of Sciences USA 97, 3370-3374.
- Cheema, U.S., Roschke, V., Hubert, D.M. and Stohl, W. (2001) "Elevated serum B Lymphocyte Stimulator levels in patients with systemic immune-based rheumatic diseases". Arthritis and Rheumatism 44, 1313-1319.
- Zhang, J., Roschke, V., Baker, K.P., Wang, Z., Alarcon, G.S., Pessler, B.J., Bastian, H., Kimberly, R.P. and Zhou, T. (2001) "A role for B lymphocyte stimulator in systemic lupus erythematosus". Journal of Immunology 166, 6-10.
- Yu, G., Boone, T., Delaney, J., Hawkins, N., Kelley, M., Ramakrishnan, M., McCabe, S., Qiu, W.-R., Korauc, M., Xia, X.-Z., Guo, J., Stolina, M., Boyle, W.J., Sarosi, I., Hsu, H., Senaldi, G. and Theill, L.E. (2000) "APRIL and TALL-1 and receptors BCMA and TACI: system for regulating humoral immunity", Nature Immunology 1, 252-256.
- Briones, J., Timmerman, J., Hilbert, D.M. and Levy, R. (2002) "BLyS and BLyS receptor expression in non-Hodgkin's lymphoma", Experimental Hematology 30, 135-141.
- Parry, T., Riccobene, T.A., Strawn, S.J., Williams, R., Daoud, R., Carrell, J., Sosnovtseva, S., Miceli, R.C., Poortman, C.M., Sekut, L., Li, Y., Fikes, J. and Sung, C. (2001) "Pharmacokinetics and immunological effects of exogenously administered recombinant human B lymphocyte stimulator (BLyS) in mice". Journal of Pharmacology and Experimental Therapeutics 296, 396-404.
- Ferraiolo, B.L., Moore, J.A., Crase, D., Gribling, P., Wilking, H. and Baughman, R.A. (1988) "Pharmacokinetics and tissue distribution of recombinant human tumor necrosis factor-alpha in mice". Drug Metabolism and Disposition 16, 270-275.
- Walczak, H., Miller, R.E., Ariail, K., Gliniak, B., Griffith, T.S., Kubin, M., Chin, W., Jones, J., Woodward, A., Le, T., Smith, C., Smolak, P., Goodwin, R.G., Rauch, C.T., Schuh, J.C. and Lynch, D.H. (1999) "Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in viva", Nature Medicine 5, 157-163.
- Mordenti, J., Chen, S.A., Moore, J.A., Ferraiolo, B.L. and Green, J.D. (1991) "Interspecies scaling of clearance and volume of distribution data for five therapeutic proteins". Pharmacology Research 8, 1351-1359.
B Lymphocyte Stimulator (BLyS): A Therapeutic Trichotomy for the Treatment of B Lymphocyte Diseases
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.