Allelotyping in B-Cell Chronic Lymphocytic Leukemia (B-CLL)

References

• Guipaud, O., Deriano, L., Salin, H., et al. (2003) "B-cell chronic lymphocytic leukemia: a polymorphic family unified by genomic features", Lancet OncoL, 4(8), 505–514.
   PubMedGoogle Scholar
• Matutes, E. and Polliack, A. (2000) "Morphological and immuno-phenotypic features of chronic lymphocytic leukemia", Rev. Clin. Exp. HematoL, 4(1), 22–47.
   Google Scholar
• Fais, F., Ghiotto, F., Hashimoto, S., et al. (1998) "Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors", J. Clin. Invest., 102(8), 1515 — 1525.
   Google Scholar
• Hamblin, T.J., Davis, Z., Gardiner, A., Oscier, D.G. and Stevenson, F.K. (1999) "Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia", Blood, 94(6), 1848 — 1854.
   PubMed Web of Science ®Google Scholar
• Damle, RN., Wasil, T., Fais, F., et al. (1999) "Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia", Blood, 94(6), 1840 — 1847.
   PubMed Web of Science ®Google Scholar
• Klein, U., Tu, Y., Stolovitzky, GA., et al. (2001) "Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells", J. Exp. Med., 194(11), 1625–1638.
   PubMed Web of Science ®Google Scholar
• Rosenwald, A., Alizadeh, A.A., Widhopf, G., et al. (2001) "Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia", J. Exp. Med., 194(11), 1639 — 1647.
   PubMed Web of Science ®Google Scholar
• Stilgenbauer, S., Bullinger, L., Lichter, P., and Dohner, H. (2002) "Genetics of chronic lymphocytic leukemia: genomic aberrations and V(H) gene mutation status in pathogenesis and clinical course", Leukemia, 16(6), 993–1007.
   PubMed Web of Science ®Google Scholar
• Mitelman, F. and Levan, G. (1978) "Clustering of aberrations to specific chromosomes in human neoplasms. III. Incidence and geographic distribution of chromosome aberrations in 856 cases", Hereditas, 89(2), 207–232.
   PubMed Web of Science ®Google Scholar
• Juliusson, G., Gahrton, G., Oscier, D., et al. (1991) "Cytogenetic findings and survival in B-cell chronic lymphocytic leukemia. Second IWCCLL compliation of data on 662 patients", Leuk. Lymphoma, 5, 21–25.
   PubMed Web of Science ®Google Scholar
• Dohner, H., Stilgenbauer, S., Benner, A., et al. (2000) "Genomic aberrations and survival in chronic lymphocytic leukemia", N. Engl. J. Med., 343(26), 1910— 1916.
   Google Scholar
• el Rouby, S., Thomas, A., Costin, D., et al. (1993) "p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expres-sion", Blood, 82(11), 3452— 3459.
   PubMed Web of Science ®Google Scholar
• Dohner, H., Fischer, K., Bentz, M., et al. (1995) "p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias", Blood, 85(6), 1580— 1589.
   PubMed Web of Science ®Google Scholar
• Barnabas, N., Shurafa, M., Van Dyke, D.L., Wolman, S.R., Clark, D. and Worsham, M.J. (2001) . "Significance of p53 mutations in patients with chronic lymphocytic leukemia: a sequential study of 30 patients", Cancer, 91(2), 285 — 293.
   PubMed Web of Science ®Google Scholar
• Doneda, L., Montillo, M., Intropido, L., Tedeschi, A., Morra, E. and Larizza, L. (2003) . "Interphase fluorescence in situ hybridiza-tion analysis of del(11)(q23) and del(17)(p13) in chronic lymphocy-tic leukemia, a study of 40 early-onset patients", Cancer Genet. Cytogenet., 140(1), 31–36.
   Google Scholar
• Starostik, P., Manshouri, T., O'Brien, S., et al. (1998) . "Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia", Cancer Res., 58(20), 4552 — 4557.
   PubMed Web of Science ®Google Scholar
• Bullrich, F., Rasio, D., Kitada, S., et al. (1999) "ATM mutations in B-cell chronic lymphocytic leukemia", Cancer Res., 59(1), 24 — 27.
   PubMed Web of Science ®Google Scholar
• Stankovic, T., Weber, P., Stewart, G., et al. (1999) "Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukemia", Lancet, 353(9146), 26–29.
   PubMed Web of Science ®Google Scholar
• Schaffner, C., Stilgenbauer, S., Rappold, G.A., Dohner, H. and Lichter, P. (1999) "Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia", Blood, 94(2), 748 —753.
   PubMed Web of Science ®Google Scholar
• Kapanadze, B., Makeeva, N., Corcoran, M., et al. (2000) "Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14", Genomics, 70(3), 327 — 334.
   PubMed Web of Science ®Google Scholar
• Migliazza, A., Bosch, F., Komatsu, H., et al. (2001) "Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leuke-mia", Blood, 97(7), 2098 — 2104.
   PubMed Web of Science ®Google Scholar
• Mabuchi, H., Fujii, H., CalM, G., et al. (2001) "Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia", Cancer Res., 61(7), 2870— 2877.
   PubMed Web of Science ®Google Scholar
• Bullrich, F., Fujii, H., Calm, G., et al. (2001) "Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene", Cancer Res., 61(18), 6640— 6648.
   PubMed Web of Science ®Google Scholar
• Wolf, S., Mertens, D., Schaffner, C., et al. (2001) "B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions", Hum. MoL Genet., 10(12), 1275 — 1285.
   Google Scholar
• Mertens, D., Wolf, S., Schroeter, P., et al. (2002) "Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia", Blood, 99(11), 4116–4121.
   PubMed Web of Science ®Google Scholar
• Sossey-Alaoui, K., Kitamura, E., Head, K. and Cowell, J.K. (2003) "Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer", Genomics, 80(1), 5 — 7.
   Web of Science ®Google Scholar
• Calm, GA., Dumitru, C.D., Shimizu, M., et al. (2002) "Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia", Proc. Natl. Acad. Sci. USA, 99(24), 5524–5529.
   Google Scholar
• Rowntree, C., Duke, V., Panayiotidis, P., et al. (2002) "Deletion analysis of chromosome 13q14.3 and characterisation of an alternative splice form of LEU1 in B cell chronic lymphocytic leukemia", Leukemia, 16(7), 1267 — 1275.
   PubMed Web of Science ®Google Scholar
• Ivanov, DV., Tyazhelova, TV., Lemonnier, L., et al. (2003) "A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3", FEBS Lett., 539(1–3), 156— 160.
   Google Scholar
• Gozzetti, A. and Le Beau, M.M. (2000) "Fluorescence in situ hybridization: uses and limitations", Semin. Hematol., 37(4), 320–333.
   Web of Science ®Google Scholar
• Lichter, P., Joos, S., Bentz, M. and Lampel, S. (2000) "Comparative genomic hybridization: uses and limitations", Semin. Hematol., 37(4), 348 — 357.
   Web of Science ®Google Scholar
• Bentz, M., Huck, K., du Manoir, S., et al. (1995) "Comparative genomic hybridization in chronic B-cell leukemias shows a high incidence of chromosomal gains and losses", Blood, 85(12), 3610 — 3618.
   PubMed Web of Science ®Google Scholar
• Schwanen, C., Nessling, M., Wessendorf, S., et al. (2001) "Auto-mated genomic profiling in chronic lymphocytic leukemia using microarray-based hybridization (Matrix-CGH)", Blood, 98\(Suppl. 1), Abstract 3178.
   Google Scholar
• Ottaggio, L., Viaggi, S., Zunino, A., et al. (2003) "Chromosome aberrations evaluated by comparative genomic hybridization in B-cell chronic lymphocytic leukemia: correlation with CD38 expres-sion", Haematologica, 88(7), 769–777.
   PubMed Web of Science ®Google Scholar
• Weissenbach, J., Gyapay, G., Dib, C., et al. (1992) "A second-generation linkage map of the human genome", Nature, 359(6398), 794 —801.
   PubMed Web of Science ®Google Scholar
• Dib, C., Faure, S., Fizames, C., et al. (1996) "A comprehensive genetic map of the human genome based on 5,264 microsatellites [see comments]", Nature, 380(6570), 152— 154.
   PubMed Web of Science ®Google Scholar
• McPherson, J.D., Marra, M., Hillier, L., et al. (2001) "A physical map of the human genome", Nature, 409(6822), 934–941.
   PubMed Web of Science ®Google Scholar
• Martin, J.B. (1999) "Molecular basis of the neurodegenerative disorders", N. Engl. J. Med., 340(25), 1970— 1980.
   Google Scholar
• Gelmann, E.P. (2002) "Molecular biology of the androgen receptor", J. Clin. °flea, 20(13), 3001 — 3015.
   Google Scholar
• Goldin, L.R., Ishibe, N., Sgambati, M., et al. (2003) "A genome scan of 18 families with chronic lymphocytic leukemia", Br. J. Haematol., 121(6), 866–873.
   Web of Science ®Google Scholar
• Pabst, T., Schwaller, J., Tobler, A. and Fey, M.F. (1996) "Detection of microsatellite markers in leukemia using DNA from archival bone marrow smears", Br. J. Haematol., 95(1), 135–137.
   Web of Science ®Google Scholar
• Hasse, U., Tinguely, M., Leibundgut, E.O., et al. (1999) "Clonal loss of heterozygosity in microdissected Hodgkin and Reed-Sternberg cells", J. Natl. Cancer Inst., 91(18), 1581–1583.
   Google Scholar
• Canzian, F., Salovaara, R., Hemminki, A., et al. (1996) "Semi-automated assessment of loss of heterozygosity and replication error in tumors", Cancer Res., 56(14), 3331 — 3337.
   PubMed Web of Science ®Google Scholar
• Pabst, T., Schwaller, J., Bellomo, M.J., et al. (1996) "Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias", Blood, 88(3), 1026— 1034.
   PubMed Web of Science ®Google Scholar
• Novak, U., Oppliger Leibundgut, E., Hager, J., et al. (2002) "A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL)", Blood, 100(5), 1787 — 1794.
   Web of Science ®Google Scholar
• Lengauer, C., Kinzler, K.W. and Vogelstein, B. (1998) "Genetic instabilities in human cancers", Nature, 396(6712), 643–649.
   PubMed Web of Science ®Google Scholar
• Knudson, A.G. Jr. "Mutation and cancer: statistical study of retinoblastoma", Proc. Natl. Acad. Sci. USA, 68(4), 820–823.
   Google Scholar
• Jones, M.H. and Nakamura, Y. (1992) "Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism", Genes Chromosomes Cancer, 5(1), 89–90.
   PubMed Web of Science ®Google Scholar
• Vogelstein, B., Fearon, E.R. and Kern, SE, et al. (1989) "Allelotype of colorectal carcinomas", Science, 244(4901), 207 — 211.
   PubMed Web of Science ®Google Scholar
• Cave, H., Guidal, C., Elion, J., Vilmer, E. and Grandchamp, B. (1996) "A low rate of loss of heterozygosity is found at many different loci in childhood B-lineage acute lymphocytic leukemia", Leukemia, 10(9), 1486–1491.
   PubMed Web of Science ®Google Scholar
• Takeuchi, S., Bartram, CR., Wada, M., et al. (1995) "Allelotype analysis of childhood acute lymphoblastic leukemia", Cancer Res., 55(22), 5377–5382.
   PubMed Web of Science ®Google Scholar
• Chambon-Pautas, C., Cave, H., Gerard, B., et al. (1998) "High-resolution allelotype analysis of childhood B-lineage acute lympho-blastic leukemia", Leukemia, 12(7), 1107–1113.
   PubMed Web of Science ®Google Scholar
• Sweetser, D.A., Chen, CS., Blomberg, A.A., et al. (2001) "Loss of heterozygosity in childhood de novo acute myelogenous leukemia", Blood, 98(4), 188 — 194.
   Web of Science ®Google Scholar
• Mori, N., Morosetti, R., Lee, S., et al. (1997) "Allelotype analysis in the evolution of chronic myelocytic leukemia", Blood, 90(5), 2010 — 2014.
   Web of Science ®Google Scholar
• Rigaud, G., Moore, P.S., Taruscio, D., et al. (2001) "Alteration of chromosome arm 6p is characteristic of primary mediastinal B-cell lymphoma, as identified by genome-wide allelotyping", Genes Chromosomes Cancer, 31(2), 191–195.
   PubMed Web of Science ®Google Scholar
• Fegan, C. (2001) "Molecular abnormalities in B-cell chronic lymphocytic leukemia", Clin. Lab. Haematol., 23(3), 139 — 148.
   PubMedGoogle Scholar
• Hernandez, J.M., Mecucci, C., Criel, A., et al. (1995) "Cytogenetic analysis of B cell chronic lymphoid leukemias classified according to morphologic and immunophenotypic (FAB) criteria", Leukemia, 9(12), 2140–2146.
   PubMed Web of Science ®Google Scholar
• Jarosova, M., Jedlickova, K., Holzerova, M., et al. (2001) "Contribution of comparative genomic hybridization and fluores-cence in situ hybridization to the detection of chromosomal abnormalities in B-cell chronic lymphocytic leukemia", Onkologie, 24(1), 60 — 65.
   PubMed Web of Science ®Google Scholar
• Gartenhaus, R., Johns, MM., Wang, P., Rai, K. and Sidransky, D. (1996) "Mutator phenotype in a subset of chronic lymphocytic leukemia", Blood, 87(1), 38–41.
   PubMed Web of Science ®Google Scholar
• Gartenhaus, R.B. (1997) "Allelic loss determination in chronic lymphocytic leukemia by immunomagnetic bead sorting and microsatellite marker analysis", Oncogene, 14(3), 375 — 378.
   PubMed Web of Science ®Google Scholar
• Volpe, G., Gamberi, B., Pastore, C., et al. (1996) "Analysis of microsatellite instability in chronic lymphoproliferative disorders", Ann. Hematol., 72(2), 67–71.
   Web of Science ®Google Scholar
• Mao, L. (2000) "Microsatellite analysis. Applications and pitfalls", Ann. N. Y. Acad. Sci., 906, 55–62.
   PubMed Web of Science ®Google Scholar
• Leupin, N., Cenni, B., Novak, U., et al. (2003) "Disparate expression of the PTEN gene: a novel finding in B-cell chronic lymphocytic leukemia (B-CLL)", Br. J. Haematol., 121(1), 97–100.
   Web of Science ®Google Scholar
• Wiley, J.S., Dao-Ung, L.P., Gu, B.J., et al. (2002) "A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukemia: a molecular study", Lancet, 359(9312), 1114 — 1119.
   PubMed Web of Science ®Google Scholar
• Dewald, G.W., Brockman, SR., Paternoster, S.F., et al. (2003) "Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukemia", Br. J. Haematol., 121(2), 287 — 295.
   Web of Science ®Google Scholar
• Karhu, R., Tobin, G., Thunberg, U., et al. (2003) "More extensive genetic alterations in unmutated than in hypermutated cases of chronic lymphocytic leukemia", Genes Chromosomes Cancer, 37(4), 417–420.
   PubMed Web of Science ®Google Scholar
• Fegan, C., Robinson, H., Thompson, P., Whittaker, J.A. and White, D. (1995) "Karyotypic evolution in CLL: identification of a new sub-group of patients with deletions of 11 q and advanced or progressive disease", Leukemia, 9(12), 2003–2008.
   PubMed Web of Science ®Google Scholar
• Finn, W.G., Kay, N.E., Kroft, S.H., Church, S. and Peterson, L.C. (1998) "Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: a sequential study of karyotypic instability in 51 patients", Am. J. Hematol., 59(3), 223–229.
   PubMed Web of Science ®Google Scholar
• Leupolt, E., Stilgenbauer, S., Krober, A., Bullinger, L., Lichter, P. and Dohner, H. (2001) "Clonal evolution in B-CLL: acquisition of deletions involving 6q21, 11q22 and 17p13 (TP53) associated with disease progression", Blood, 98 (Supp1.1), Abstract 1968.
   Google Scholar
• Cuneo, A., Bigoni, R., Rigolin, G.M., et al. (2002) "Late appearance of the 11q22.3-23.1 deletion involving the ATM locus in B-cell chronic lymphocytic leukemia and related disorders. Clinico-biological significance", Haematologica, 87(1), 44–51.
   PubMed Web of Science ®Google Scholar
• Bea, S., Lopez-Guillermo, A., Ribas, M., et al. (2002) "Genetic imbalances in progressed B-cell chronic lymphocytic leukemia and transformed large-cell lymphoma (Richter's syndrome)", Am. J. Pathol., 161(3), 957–968.
   PubMed Web of Science ®Google Scholar
• Fulop, Z., Csernus, B., Timar, B., Szepesi, A. and Matolcsy, A. (2003) "Microsatellite instability and hMLH1 promoter hyper-methylation in Richter's transformation of chronic lymphocytic leukemia", Leukemia, 17(2), 411–415.
   PubMed Web of Science ®Google Scholar
• Crespo, M., Bosch, F., Villamor, N., et al. (2003) "ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia", N. Engl. J. Med., 348(18), 1764–1775.
   Google Scholar