Effect of 1,25(OH)₂ Vitamin D₃ Analogs on Differentiation Induction and Cytokine Modulation in Blasts from Acute Myeloid Leukemia Patients

References

• Tenen, D.G. (2003) "Disruption of differentiation in human cancer: AML shows the way", Nature Reviews, 3, 89 — 101.
   Web of Science ®Google Scholar
• Gattei, V., Degan, M., Aldinucci, D., De Tullis, A., Rossi, F.M., Mazzocco, F.T., et al. (1998) "Differential expression of the RET gene in human acute myeloid leukemia", Annals of Hematology, 77(5), 207 — 210.
   PubMed Web of Science ®Google Scholar
• Lococo, F., Zelant, A., Kimchi, A., Carducci, M., Gore, S.D. and Waxman, S. (2002) "Progress in differentiation induction as a treatment for acute promyelocytic leukemia and beyond", Cancer Research, 62, 5618 — 5621.
   Google Scholar
• Mauro, M.J. and Druker, B.J. (2001) "STI-571: Targeting BCR-ABL as therapy for CML", The Oncologist, 6, 233–238.
   PubMed Web of Science ®Google Scholar
• Elstner, E., Lee, Y.Y., Hashiya, M., Pakkala, S., Binderup, L., Norman, A.W., et al. (1994) "1a, 25-Dihydroxy-20-epi- Vitamin D3: An extraordinary potent inhibitor of leukemic cell growth in vitro", Blood, 84, 1960–1967.
   Google Scholar
• Guzey, M., Kitada, S. and Reed, J.C. (2002) "Apoptosis induction by 1, 25- Dihydroxyvitamin D3 in prostate cancer", Molecular Cancer Therapeutics, 1, 667–677.
   PubMed Web of Science ®Google Scholar
• Hansen, CM., Hansen, D., Holm, P.K. and Binderup, L. (2001) "Vitamin D compounds exert anti-apoptotic effects in human osteocarcinoma cells in vitro", Journal of Steroid Biochemistry and Molecular Biology, 77, 1–11.
   Google Scholar
• Hershberger, P.A., Modzelewslci, R.A., Shurin, Z.R., Reueger, R.M., Trump, D.L. and Johnson, CS. (1999) "1, 25-Dihydroxy-cholecalciferol (1,25-D3) inhibits the growth of squamous cell carcinoma and down modulates p21(Waf licip 1) in vitro and in vivo", Cancer Research, 59, 2644–2649.
   PubMed Web of Science ®Google Scholar
• Hisatake, J., O'Kelly, J., Uskokovic, M.R., Tomoyasu, S. and Koeffler, H.P. (2001) "Novel Vitamin D3 analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D3, that modulates cell growth, differentia-tion, apoptosis, cell cycle, and induction of PTEN in leukemic cells", Blood, 97, 2427 — 2433.
   Google Scholar
• Jensen, S.S., Winkel, MM., Lukas, J., Binderup, L. and Bartek, J. (2001) "Inhibitory effects of 1a-25-Dihydroxyvitamin D3 on the GI-S phase-controlling machinery", Molecular Endocrinology, 15, 1370— 1380.
   Google Scholar
• Miller, G.J., Stapleton, G.E., Hedlund, T.E. and Moffat, K.A. (1995) "Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1, 25-Dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines", Clinical Cancer Research, 1, 997–1003.
   PubMed Web of Science ®Google Scholar
• Srivastava, M.D., Ambrus, J.L. and Uskokovic, M.R. (1995) "Calcitriol analogs cause differentiation of neoplastic cells in culture", Research Communications in Molecular Pathology and Pharmacology, 88, 77–85.
   Google Scholar
• Srivastava, M.D., DeLuca, H.F. and Ambrus, J.L. (1994) "Differ-entiation of neoplastic cells toward normal induced by Vitamin D3 derivatives", Research Communications in Chemical Pathology and Pharmacology, 83, 115 — 123.
   Google Scholar
• Jung, S.J., Lee, Y.Y., Pakkala, S., Devos, E., Elstner, E., Norman, A.W., et al. (1994) "1,25(OH)2-16 ene-Vitamin D3 is a potent antileukemic agent with low potential to cause hypercalcemia", Leukemia Research, 18, 453–463.
   PubMed Web of Science ®Google Scholar
• Zhou, J.Y., Norman, A.W., Lubert, M., Collins, ED., Uskokovic, M.R. and Koeffler, H.P. (1989) "Novel vitamin D analogs that modulate leukemic cell growth and differentiation with little effect of either intestinal calcium absorption or bone calcium mobilization", Blood, 74, 82–93.
   Google Scholar
• Adorini, L. (2002) "Immunomodulatory effects of Vitamin D receptor ligands in autoimmune diseases", International Immuno-pharmacology, 2, 1017 — 1028.
   Google Scholar
• Berry, D., Clark, C.S. and Meckling-Gill, K.A. (2002) "la, 25-Dihydroxyvitamin D3 stimulates phosphorylation of IKBa and synergizes with TPA to induce nuclear translocation of NFKB during monocytic differentiation of NB4 leukemia cells", Experi-mental Cell Research, 272, 176 — 184.
   Google Scholar
• Srivastava, M.D. (1995) Modulation of proinflammatory cytolcine production by human hematopoietic cell lines. Ph.D. Thesis, State University of New York at Buffalo, USA 1995.
   Google Scholar
• Srivastava, M.D., DeLuca, H.F. and Ambrus, J.L. (1994) "Inhibi-tion of IL-6 and IL-8 produciton in human fibroblast cell lines by 1,25(OH)2 Vitamin D3 and two of its analogs with lower calcemic activity", Research Communications in Chemical Pathology and Pharmacology, 83, 145–150.
   PubMedGoogle Scholar
• Behringer, D., Schaufler, J., Kresin, V., Lubbert, M. and Lindemann, A. (2001) "Differentiation associated modulation of the cytolcine and chemolcine expression pattern in human myeloid cell lines", Leukemia Research, 25, 141–149.
   Google Scholar
• D'Ambrosio, D., Cippitelli, M., Cocciolo, M.G., Mazzeo, D., DiLucia, P., Lang, R., et al. (1998) "Inhibition of IL-12 production by 1,25-Dihydroxyvitamin D3. Involvement of NF-KB down regulation in transcriptional repression of the p40 gene", Journal of Clinical Investigation, 101, 252— 262.
   Google Scholar
• Harant, H., Andrew, P.J., Reddy, G.S., Foglar, E. and Lindley, LI (1997) "1-alpha,25-Dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nuclear-factor-Kappa B mediated interleulcin-8 gene expression", European Journal of Biochemistry, 250, 63–71.
   Google Scholar
• Kang, S., Griffiths, CE., Fancher, L., Hamilton, T.A. and Choi, J.H. (1998) "Calcipotriene-induced improvement in psoriasis is associated with reduced interleulcin-8 and increased interleulcin-10 levels within lesions", British Journal of Dermatology, 138, 77–83.
   PubMed Web of Science ®Google Scholar
• Masood, R., Nagpal, S., Zheng, T., Cai, J., Tulpule, A., Smith, DL., et al. (2000) "Kaposi's sarcoma is a therapeutic target for Vitamin D3 receptor agonist", Blood, 96, 3188–3194.
   PubMed Web of Science ®Google Scholar
• Muller, K., Haahr, P.M., Diamant, M., Rieneck, K., Kharazmi, A. and Bendtzen, K. (1992) "1,25,dihydroxyvitamin D3 inhibits cytolcine production by human blood monocytes at the post-transcriptional level", Cytokine, 4, 506 — 512.
   Google Scholar
• Reichel, H., Koeffler, H.P., Tobler, A. and Norman, A.W. (1987) "1-alpha, 25-dihydroxyvitamin D3 inhibits gamma interferon synthesis by normal human peripheral blood lumphocytes", Proceedings of the National Academy of Science, 84, 3385–3390.
   PubMed Web of Science ®Google Scholar
• Zhang, J.Z., Maruyama, K., Ono, I., Iwatsulci, K. and Kaneko, F. (1994) "Regulatory effects of 1,25,dihydroxyvitamin D3 and a novel Vitamin D3 analog MC903 on secretion of interleulcin-1 alpha (IL-1 alpha) and IL-8 by normal human keratinocytes and a human squamous cell carcinoma cell line (HSC-1)", Journal of Dermato-logic Science, 7, 24–31.
   PubMedGoogle Scholar
• Yamada, S., Shimizu, M. and Yamamoto, K. (2003) "Structure — function relationships of Vitamin D including ligand recognition by the Vitamin D receptor", Medical Research Reviews, 23, 89–115.
   Google Scholar
• Li, C., Wang, Y., Gao, L., Zhang, J., Shao, J., Wang, S., et al. (2002) "Expression of Toll-like receptors 2 and 4 and CD14 during differentiation of HL-60 cells induced by phorbol 12-myristate 13-acetate and la, 25-dihydroxy-Vitamin D3", Cell Growth and Differentiation, 13, 27–38.
   PubMedGoogle Scholar
• Danilenko, M., Wang, X. and Studzinslci, G.P. (2001) "Carsonic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents", Journal of the National Cancer Institute, 93, 1224— 1233.
   Google Scholar
• Funatolci, M., Miyazawa, F.K., Yaguchi, M., Gotoh, A. and Ohyashilci, K. (2002) "Combination of 22-0XA-1, 25-dihydrox-yvitamin D3, a Vitamin D3 derivative, with Vitamin K2 (VK2) synergistically enhances cell differentiation but suppresses VK2 — inducing apoptosis in HL-60 cells", Leukemia, 16, 1519–1527.
   PubMed Web of Science ®Google Scholar
• Gullberg, U., Nilsson, E., Einhorn, E. and Olsson, I. (1985) "Combinations of interferon gamma and retinoic acid or 1-alpha, 25-dihydroxychole-calciferol induce differentiation of the human monoblast leukemia cell line U-937", Experimental Hematology, 13, 675— 679.
   Google Scholar
• Nakagawa, K., Sowa, Y., Kurobe, M., Ozono, K., Caldera, M.L.S., Reddy, G.S., et al. (2001) "Differential activities of la,25-dihydroxy-16-ene-Vitamin D3 analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis", Steroids, 66, 327–337.
   PubMed Web of Science ®Google Scholar
• Nhtsu, N., Hayashi, Y., Sugita, K. and Honma, Y. (2001) "Sensitization by 5-aza-21-deoxycytidine of leukemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and la, 25-dihydroxyvitamin D3", British Journal of Haematology, 112, 315–326.
   PubMed Web of Science ®Google Scholar
• Norman, A.W., Zhou, J.Y., Henry, H.L., Uskokovic, M.R. and Koeffler, H.P. (1990) "Structure function studies on analogues of la,25-dihydroxy-vitamin D3: Differential effects on leukemic cell growth, differentiation, and intestinal calcium absorption", Cancer Research, 50, 6857 — 6864.
   Google Scholar
• Savli, H., Aslto, Y., Nagy, B., Knuvtila, S. and Pakkala, S. (2002) "Gene expression analysis of 1, 25(OH)2 D3 dependent differentia-tion of HL-60 cells: a cDNA array study", British Journal of Haematology, 118, 1065 — 1070.
   PubMed Web of Science ®Google Scholar
• Tagliafico, E., Tenedini, E., Bergamaschi, A., Manfredini, R., Percudani, R., Siena, M., et al. (2002) "Gene expression profile of Vitamin D3 treated HL-60 cells shows an incomplete molecular phenotypic conversion to monocytes", Cell Death and Differentia-tion, 9, 1185–1195.
   PubMed Web of Science ®Google Scholar
• Trayner, ID., Bustorff, T., Etches, A.E., Mufti, G.J., Foss, Y. and Farzaneh, F. (1998) "Changes in antigen expression on differentiat-ing HL-60 cells treated with dimethylsulphoxide, all-trans retinoic acid, al, 25-dihydroxy-vitamin D3 or 12-0-tetradecanoylphorbol-13-acetate", Leukemia Research, 22, 537— 547.
   Google Scholar
• Yamada, K., Honma, Y., Asahi, K.I., Sassa, T., Hino, K.I. and Tomoyasu, S. (2001) "Differentiation of human acute myeloid leukemia cells in primary culture in response to cotylenin A, a plant growth regulator", British Journal of Haematology, 114, 814–821.
   Google Scholar
• Scheper, R.J., Butte, J.W.M., Brakkee, J.G.P., Quak, J.J., Van der Schoot, E., Balm, A.J.M., et al. (1988) "Monoclonal antibody JSB-1 detects a highly conserved epitope on the p-glycoprotein associated with multi-drug resistance", International Journal of Cancer, 42, 389— 394.
   Google Scholar
• Al-alami, O., Sammons, J., Martin, J.H. and Hassan, H.T. (1998) "Divergent effect of taxol on proliferation, apoptosis and nitric oxide production in MHH225 CD34 positive and U-937 CD34 negative human leukemia cells", Leukemia Research, 22, 939–945.
   PubMed Web of Science ®Google Scholar
• Srivastava, M.D., Ambrus, J.L. and Srivastava, B.I.S. (1998) Cytolcine production by normal and malignant human cell lines. In Proceedings of the 17th International Cancer Congress Rio de Janeiro, 1998, edited by M. Morales, R. Brentani and R. Bevilacqua. Pp 115–118. Bologna (Italy): Monduzzi Editions SPA.
   Google Scholar
• Honma, Y. and Ishii, Y. (2002) "Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones", Leukemia and Lymphoma, 43(9), 1729— 1735.
   Web of Science ®Google Scholar
• Bruserud, O. and Gjertsen, B.T. (2000) "New strategies for the treatment of acute myelogenous leukemia: differentiation induc-tion—present use and future possibilities", Stem Cells, 18(3), 157 — 165.
   PubMed Web of Science ®Google Scholar
• Olsson, I., Bergh, G., Ehinger, M. and Gullberg, U. (1996) "Cell differentiation in acute myeloid leukemia", European Journal of Haematology, 57(1), 1–16.
   PubMed Web of Science ®Google Scholar
• Paul, C.C., Aly, E., Lehman, JA., Page, S.M., Gomez-Cambronero, J., Ackerman, Si., et al. (2000) "Human cell line that differentiates to all myeloid lineages and expresses neutrophil secondary granule genes", Experimental Hematology, 28(12), 1373— 1380.
   PubMed Web of Science ®Google Scholar
• Nakajima, K., Yamanaka, Y., Nakae, K., Kojima, H., Ichiba, M., Kiuchi, N., et al. (1996) "A central role for Stat3 in IL-6 induced regulation of growth and differentiation in M1 leukemia cells", EMBO Journal, 15(14), 3651–3658.
   PubMed Web of Science ®Google Scholar