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Original Article

Extracellular matrix in bone marrow can mediate drug resistance in myeloma

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Pages 803-811 | Received 04 Dec 2004, Published online: 03 Aug 2009

References

  • Bataille R, Harousseau JL. Multiple myeloma. N Engl J Med 1997;336:1657 - 1664.
  • Shain KH, Landowski TH, Dalton WS. The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance. Curr Opin Oncol 2000;12:557 - 563.
  • Vincent T, Jourdan M, Sy MS, Klein B, Mechti N. Hyaluronic acid induces survival and proliferation of human myeloma cells through an interleukin-6-mediated pathway involving the phosphorylation of retinoblastoma protein. J Biol Chem 2001;276:14728 - 14736.
  • Klein B, Zhang XG, Lu ZY, Bataille R. Interleukin-6 in human multiple myeloma. Blood 1995;85:863 - 872.
  • Kyle RA, Rajkumar SV. Multiple myeloma. N Engl J Med 2004;351:1860 - 1873.

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