Inactivation of tumor suppressor genes and the progression of adult T-cell leukemia-lymphoma

References

• Uchiyama T, Yodoi J, Sagawa K, Takatsuki K, Uchino H. Adult T cell leukemia: clinical and hematologic features of 16 cases. Blood 1977; 50: 481–492
   PubMed Web of Science ®Google Scholar
• Poiesz B J, Ruscetti F W, Gazdar A F, Bunn P A, Minna J D, Gallo R C. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patients with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980; 77: 7415–7419
   PubMed Web of Science ®Google Scholar
• Yoshida M, Seiki M, Yamaguchi K, Takatsuki K. Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. Proc Natl Acad Sci USA 1984; 81: 2534–2537
   PubMed Web of Science ®Google Scholar
• Kinoshita K, Amagasaki T, Ikeda S, Suzuyama J, Toriya K, Nishino K, et al. Preleukemic state of adult T cell leukemia: abnormal T lymphocytosis induced by human adult T cell leukemia-lymphoma virus. Blood 1985; 66: 120–127
   PubMed Web of Science ®Google Scholar
• Shimoyama M, members of The Lymphoma Study Group (1984–1987). Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma: a report from the lymphoma study group (1984–1987). Br J Haematol 1991; 79: 428–437
   PubMed Web of Science ®Google Scholar
• Kinoshita K, Hino S, Amagasaki T, Ikeda S, Yamada Y, Suzuyama J, et al. Demonstration of adult T-cell leukemia virus antigen in milk from three sero-positive mothers. Gann (Jpn J Cancer Res) 1984; 75: 103–105
   PubMed Web of Science ®Google Scholar
• Kinoshita K, Amagasaki T, Hino S, Doi H, Yamanouchi K, Ban N, et al. Milk-borne transmission of HTLV-1 from carrier mothers to their children. Jpn J Cancer Res 1987; 76: 1147–1153
   Google Scholar
• Jeang K T. Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-κB. Cytokine Growth Factor Rev 2001; 12: 207–217
   PubMed Web of Science ®Google Scholar
• Yoshida M. Molecular biology of HTLV-1: pleiotropic function of Tax protein in cell regulation. Gann monograph on cancer research No.50, two decades of adult T-cell leukemia and HTLV-1 research, K Sugamura, T Uchiyama, M Matsuoka, M Kannagi. Japan Scientific Societies Press, Tokyo 2003; 11–18
   Google Scholar
• Ohtani K, Nakamura M. Molecular mechanisms of Tax-mediated cell growth of human T lymphocytes. Gann monograph on cancer research No.50, two decades of adult T-cell leukemia and HTLV-1 research, K Sugamura, T Uchiyama, M Matsuoka, M Kannagi. Japan Scientific Societies Press, Tokyo 2003; 43–60
   Google Scholar
• Azran I, Schavinsky-Khrapunsky Y, Aboud M. Role of Tax protein in human T-cell leukemia virus type-1 leukemogenicity. Retrovirology 2004; 1: 20
   PubMedGoogle Scholar
• Sherr C J, Roberts J M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999; 13: 1501–1512
   PubMed Web of Science ®Google Scholar
• Malumbres M, Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001; 1: 222–231
   PubMed Web of Science ®Google Scholar
• Vogelstein B, Kinzler K W. Cancer genes and the pathways they control. Nat Med 2004; 10: 789–799
   PubMed Web of Science ®Google Scholar
• Hollstein M, Vogelstein B, Harris C C. p53 mutations in human cancers. Science 1991; 253: 49–53
   PubMed Web of Science ®Google Scholar
• Sheer C J, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002; 2: 103–112
   PubMed Web of Science ®Google Scholar
• El-Deiry W S. Regulation of p53 downstream genes. Semin Cancer Biol 1998; 8: 345–357
   PubMed Web of Science ®Google Scholar
• Brooks C L, Gu W. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol 2003; 15: 164–171
   PubMed Web of Science ®Google Scholar
• Kamijo T, Weber J D, Zambetti G, Zindy F, Roussel M F, Sherr C J. Functional and physical interactions of the ARF tumor supperssor with p53. Proc Natl Acad Sci USA 1998; 95: 8292–8297
   PubMed Web of Science ®Google Scholar
• Maeda T, Hobbs R M, Merghoub T, Guernah I, Zelent A, Cordon-Cardo C, et al. Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 2005; 433: 278–285
   PubMed Web of Science ®Google Scholar
• Hainaut P, Hollstein M. p53 and human cancer: the first ten thousand mutations. Adv Cancer Res 2000; 77: 81–137
   PubMed Web of Science ®Google Scholar
• Greenblatt M S, Bennett W P, Hollstein M, Harris C C. Mutations in the p53 tumor suppressor gene: clue to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54: 4855–4878
   PubMed Web of Science ®Google Scholar
• Guimaraes D P, Hainaut P. TP53: a key gene in human cancer. Biochimie 2002; 84: 83–93
   PubMed Web of Science ®Google Scholar
• Nagai H, Kinoshita T, Imamura J, Murakami Y, Hayashi K, Mukai K, et al. Genetic alteration of p53 in some patients with adult T-cell leukemia. Jpn J Cancer Res 1991; 82: 1421–1427
   PubMedGoogle Scholar
• Sugito S, Yamato K, Sameshima Y, Yokota J, Yano S, Miyoshi I. Adult T-cell leukemia: structures and expression of the p53 gene. Int J Cancer 1991; 49: 880–885
   PubMed Web of Science ®Google Scholar
• Sakashita A, Hattori T, Miller C W, Suzushima H, Asou N, Takatsuki K, Koeffler H P. Mutations of the p53 gene in adult T-cell leukemia. Blood 1992; 79: 477–480
   PubMed Web of Science ®Google Scholar
• Nishimura S, Asou N, Suzushima H, Okubo T, Fujimoto T, Osato M, et al. p53 gene mutation and loss of heterozygosity are associated with increased risk of disease progression in adult T cell leukemia. Leukemia 1995; 9: 598–604
   PubMed Web of Science ®Google Scholar
• Tawara M, Hogerzeil S J, Yamada Y, Takasaki Y, Soda H, Hasegawa H, et al. Impact of p53 aberration on the progression of adult T-cell leukemia/lymphoma. Cancer Lett 2005, in press
   Web of Science ®Google Scholar
• Schmidt E E, Ichimura K, Reifenberger G, Collins V P. CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 1994; 54: 6321–6324
   PubMed Web of Science ®Google Scholar
• Nobori T, Miura K, Wu D J, Lois A, Takabayashi K, Carson D A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994; 368: 753–756
   PubMed Web of Science ®Google Scholar
• Kamb A, Gruis N A, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian S V, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994; 264: 436–440
   PubMed Web of Science ®Google Scholar
• Ogawa S, Hangaishi A, Miyawaki S, Hirosawa S, Miura Y, Takeyama K, et al. Loss of the cyclin-dependent kinase 4-inhibitor (p16; MTS1) gene is frequent in and highly specific to lymphoid tumors in primary human hematopoietic malignancies. Blood 1995; 86: 1548–1556
   PubMed Web of Science ®Google Scholar
• Hatta Y, Hirama T, Miller C W, Yamada Y, Tomonaga M, Koeffler H P. Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTS1) genes in adult T-cell leukemia. Blood 1995; 85: 2699–2704
   PubMed Web of Science ®Google Scholar
• Yamada Y, Hatta Y, Murata K, Sugahara K, Ikeda S, Mine M, et al. Deletions of p15 and/or p16genes as a poor-prognosis factor in adult T-cell leukemia. J Clin Oncol 1997; 15: 1778–1785
   PubMed Web of Science ®Google Scholar
• Takasaki Y, Yamada Y, Sugahara K, Hayashi T, Dateki N, Harasawa H, et al. Interruption of p16 gene expression in adult T-cell leukaemia/lymphoma: clinical correlation. Br J Haematol 2003; 122: 253–259
   PubMed Web of Science ®Google Scholar
• Hofmann W K, Tsukasaki K, Takeuchi N, Takeuchi S, Koeffler H P. Methylation analysis of cell cycle control genes in adult T-cell leukemia/lymphoma. Leuk Lymphoma 2001; 42: 1107–1109
   PubMed Web of Science ®Google Scholar
• Trovato R, Cereseto A, Takemoto S, Gessain A, Watanabe T, Waldmann T, Franchini G. Deletion of the p16INK4A gene in ex vivo acute adult T cell lymphoma/leukemia cells and methylation of the p16INK4A promoter in HTLV type 1-infected T cell lines. AIDS Res Hum Retroviruses 2000; 16: 709–713
   PubMed Web of Science ®Google Scholar
• Nosaka K, Maeda M, Tamiya S, Sakai T, Mitsuya H, Matsuoka M. Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia. Cancer Res 2000; 60: 1043–1048
   PubMed Web of Science ®Google Scholar
• Hatta Y, Spirin K, Tasaka T, Morosetti R, Said J W, Yamada Y, Tomonaga M, Koeffler H P. Analysis of p18INK4C in adult T-cell leukemia (ATL) and non-Hodgkin's lymphoma. Br J Haematol 1997; 99: 665–667
   PubMed Web of Science ®Google Scholar
• Shiohara M, Spirin K, Said J W, Gombart A F, Nakamaki T, Takeuchi S, et al. Alterations of the cyclin-dependent kinase inhibitor p19 (INK4D) is rare in hematopoietic malignancies. Leukemia 1996; 10: 1897–1900
   PubMed Web of Science ®Google Scholar
• Shiohara M, Koike K, Komiyama A, Koeffler H P. p21WAF1 mutations and human malignancies. Leuk Lymphoma 1997; 26: 35–41
   PubMed Web of Science ®Google Scholar
• Hatta Y, Koeffler H P. Role tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL). Leukemia 2002; 16: 1069–1085
   PubMed Web of Science ®Google Scholar
• Morosetti R, Kawamata N, Gombart A F, Miller C W, Hatta Y, Hirama T, et al. Alterations of the p27KIP1 gene in non-Hodgkin's lymphoma and adult T-cell leukemia/lymphoma. Blood 1995; 86: 1924–1930
   PubMed Web of Science ®Google Scholar
• Hatta Y, Yamada Y, Tomonaga M, Koeffler H P. Extensive analysis of the retinoblastoma gene in adult T cell leukemia/lymphoma (ATL). Leukemia 1997; 11: 984–989
   PubMed Web of Science ®Google Scholar
• Quelle D E, Zindy F, Ashmun R A, Sherr C J. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995; 83: 993–1000
   PubMed Web of Science ®Google Scholar
• Quelle D E, Cheng M, Ashmun R A, Sherr C J. Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19Arf. Proc Natl Acad Sci USA 1997; 94: 669–673
   PubMed Web of Science ®Google Scholar
• Kamijo T, Zindy F, Roussel M F, Quelle D E, Downing J R, Ashmun R A, Grosveld G, Sherr C J. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 1997; 91: 649–659
   PubMed Web of Science ®Google Scholar