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Original

Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin

, , , , & , PhD
Pages 774-785 | Received 28 Aug 2006, Accepted 24 Dec 2006, Published online: 01 Jul 2009

References

  • Altieri D C, Marchisio P C, Marchisio C. Survivin apoptosis: an interloper between cell death and cell proliferation in cancer. Lab Invest 1999; 79: 1327–1333
  • Altieri D C. Survivin and apoptosis control. Adv Cancer Res 2003; 88: 31–52
  • Li F, Ambrosini G, Chu E Y, Plescia J, Tognin S, Marchisio P C, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998; 396: 580–584
  • Ambrosini G, Adida C, Altieri D C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917–921
  • Adida C, Berrebi D, Peuchmaur M, Reyes-Mugica M, Altieri D C. Anti-apoptosis gene, survivin, and prognosis of neuroblastoma. Lancet 1998; 351: 882–883
  • Kawasaki H, Altieri D C, Lu C D, Toyoda M, Tenjo T, Tanigawa N. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res 1998; 58: 5071–5074
  • Sarela A I, Macadam R C, Farmery S M, Markham A F, Guillou P J. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut 2000; 46: 645–650
  • Adida C, Haioun C, Gaulard P, Lepage E, Morel P, Briere J, et al. Prognostic significance of survivin expression in diffuse large B-cell lymphomas. Blood 2000; 96: 1921–1925
  • Adida C, Recher C, Raffoux E, Daniel M T, Taksin A L, Rousselot P, et al. Expression and prognostic significance of survivin in de novo acute myeloid leukaemia. Br J Haematol 2000; 111: 196–203
  • Carter B Z, Milella M, Altieri D C, Andreeff M. Cytokine-regulated expression of survivin in myeloid leukemia. Blood 2001; 97: 2784–2790
  • Carter B Z, Mak D, Schober W D, Cabreira-Hansen M, Beran M, McQueen T, et al. Regulation of survivin expression through bcr-abl/MAPK cascade: targeting survivin overcomes Imatinib resistance and increases Imatinib sensitivity in Imatinib responsive CML cells. Blood 2006; 107: 1555–1563
  • Islam A, Kageyama H, Takada N, Kawamoto T, Takayasu H, Isogai E, et al. High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma. Oncogene 2000; 19: 617–623
  • Tamm I, Wang Y, Sausville E, Scudiero D A, Vigna N, Oltersdorf T, et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 1998; 58: 5315–5320
  • Papapetropoulos A, Fulton D, Mahboubi K, Kalb R G, O'Connor D S, Li F, et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem 2000; 275: 9102–9105
  • Fornaro M, Plescia J, Chheang S, Tallini G, Zhu Y M, King M, et al. Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway. J Biol Chem 2003; 278: 50402–50411
  • Kanda N, Seno H, Konda Y, Marusawa H, Kanai M, Nakajima T, et al. STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells. Oncogene 2004; 23: 4921–4929
  • Mahboubi K, Li F, Plescia J, Kirkiles-Smith N C, Mesri M, Du Y, et al. Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway. Lab Invest 2001; 81: 327–334
  • Tran J, Rak J, Sheehan C, Saibil S D, LaCasse E, Korneluk R G, et al. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem Biophys Res Commun 1999; 264: 781–788
  • Mirza A, McGuirk M, Hockenberry T N, Wu Q, Ashar H, Black S, et al. Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene 2002; 21: 2613–2622
  • Hoffman W H, Biade S, Zilfou J T, Chen J, Murphy M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002; 277: 3247–3257
  • O'Connor D S, Grossman D, Plescia J, Li F, Zhang H, Villa A, et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci USA 2000; 97: 13103–13107
  • Zhao J, Tenev T, Martins L M, Downward J, Lemoine N R. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. J Cell Sci 2000; 113(Part 23)4363–4371
  • O'Connor D S, Wall N R, Porter A C, Altieri D C. A p34(cdc2) survival checkpoint in cancer. Cancer Cell 2002; 2: 43–54
  • Chen J, Wu W, Tahir S K, Kroeger P E, Rosenberg S H, Cowsert L M, et al. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia 2000; 2: 235–241
  • Li F, Ackermann E J, Bennett C F, Rothermel A L, Plescia J, Tognin S, et al. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1999; 1: 461–466
  • Carter B Z, Wang R -Y, Schober W D, Milella M, Chism D, Andreeff M. Targeting survivin expression induces cell proliferation defect and subsequent cell death involving the mitochondrial pathway in myeloid leukemic cell. Cell Cycle 2003; 2: 488–493
  • Wall N R, O'Connor D S, Plescia J, Pommier Y, Altieri D C. Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis. Cancer Res 2003; 63: 230–235
  • Blanc-Brude O P, Mesri M, Wall N R, Plescia J, Dohi T, Altieri D C. Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Clin Cancer Res 2003; 9: 2683–2692
  • Hwu J R, Tseng W N, Gnabre J, Giza P, Huang R C. Antiviral activities of methylated nordihydroguaiaretic acids. I. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. J Med Chem 1998; 41: 2994–3000
  • Gnabre J N, Brady J N, Clanton D J, Ito Y, Dittmer J, Bates R B, et al. Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans. Proc Natl Acad Sci USA 1995; 92: 11239–11243
  • Chen H, Teng L, Li J N, Park R, Mold D E, Gnabre J, et al. Antiviral activities of methylated nordihydroguaiaretic acids. II. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA. J Med Chem 1998; 41: 3001–3007
  • Craigo J, Callahan M, Huang R C, DeLucia A L. Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives. Antiviral Res 2000; 47: 19–28
  • Heller J D, Kuo J, Wu T C, Kast W M, Huang R C. Tetra-O-methyl nordihydroguaiaretic acid induces G2 arrest in mammalian cells and exhibits tumoricidal activity in vivo. Cancer Res 2001; 61: 5499–5504
  • Park R, Chang C C, Liang Y C, Chung Y, Henry R A, Lin E, et al. Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors. Clin Cancer Res 2005; 11: 4601–4609
  • Chang C C, Heller J D, Kuo J, Huang R C. Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression. Proc Natl Acad Sci USA 2004; 101: 13239–13244
  • Wu J, Ling X, Pan D, Apontes P, Song L, Liang P, et al. Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation associated with drug sensitivity. J Biol Chem 2005; 280: 9745–9751
  • Li Y, Xie M, Yang J, Yang D, Deng R, Wan Y, et al. The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter. Oncogene 2006; 25: 3296–3306
  • Juo P, Kuo C J, Yuan J, Blenis J. Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr Biol 1998; 8: 1001–1008
  • Datta R, Oki E, Endo K, Biedermann V, Ren J, Kufe D. XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage. J Biol Chem 2000; 275: 31733–31738
  • Beran M, Pisa P, O'Brien S, Kurzrock R, Siciliano M, Cork A, et al. Biological properties and growth in SCID mice of a new myelogenous leukemia cell line (KBM-5) derived from chronic myelogenous leukemia cells in the blastic phase. Cancer Res 1993; 53: 3603–3610
  • Martin S, Reutelingsperger C, McGahon A, Rader J, van Schie R, LaFace D, et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and ABL. J Exp Med 1995; 182: 1545–1556
  • Drach J, McQueen T, Engel H, Andreeff M, Maise R, Braylan R. Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-α. Cancer Res 1994; 54: 1746–1752
  • Carter B Z, Milella M, Tsao T, McQueen T, Schober W D, Hu W, et al. Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia. Leukemia 2003; 17: 2081–2089
  • Carter B Z, Milella M, Altieri D C, Andreeff M. Cytokine-regulated expression of survivin in myeloid leukemia. Blood 2001; 97: 2784–2790

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