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Commentary

IL-4 in lymphoma: Does the target matter?

Pages 1261-1263 | Published online: 01 Jul 2009

References

  • Nelms K, Huang H, Ryan J, Keegan A, Paul W E. Interleukin-4 receptor signalling mechanisms and their biological significance. Adv Exp Med Biol 1998; 452: 37–43
  • Choe J, Kim H S, Armitage R J, Choi Y S. The functional role of B cell antigen receptor stimulation and IL-4 in the generation of human memory B cells from germinal center B cells. J Immunol 1997; 159: 3757–3766
  • Schwarz M A, Tardelli L, Macosko H D, Sullivan L M, Narula S K, Fine J S. Interleukin 4 retards dissemination of a human B-cell lymphoma in severe combined immunodeficient mice. Cancer Res 1995; 55: 3692–3696
  • Tepper R I, Pattengale P K, Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989; 57: 503–512
  • Taylor C W, Grogan T M, Salmon S E. Effects of interleukin-4 on the in vitro growth of human lymphoid and plasma cell neoplasms. Blood 1990; 75: 1114–1118
  • Defrance T, Fluckiger A C, Rossi J F, Magaud J P, Sotto J J, Banchereau J. Antiproliferative effects of interleukin-4 on freshly isolated non-Hodgkin malignant B-lymphoma cells. Blood 1992; 79: 990–996
  • Kurtz D M, Tschetter L K, Allred J B, Greyer S M, Kurtin P J, Putnam W D, et al. Subcutaneous nterleukin-4 (IL-4) for relapsed and resistant non-Hodgkin lymphoma: a phase II trial in the North Central Cancer treatment Group, NCCTG 91-78-51. Leuk Lymph, 48: 1290–1298
  • Taylor C W, LeBlanc M, Fisher R I, Moore D F, Sr, Roach R W, Elias L, et al. Phase II evaluation of interleukin-4 in patients with non-Hodgkin's lymphoma: A Southwest Oncology Group trial. Anticancer Drugs 2000; 1: 695–700
  • Lu X, Nechushtan H, Ding F, Rosado M F, Singal R, Alizadeh A A, et al. Distinct IL-4 induced gene expression, proliferation and intracellular signaling in germinal center B-cell like and activated B-cell like diffuse large cell lymphomas. Blood 2005; 105: 2924–2932
  • Lu X, Chen J, Sasmono R T, Hsi E D, Sarosiek K A, Tiganis T, et al. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Mol Cell Biol 2007; 27: 2166–2179
  • Nechushtan H, Rosenblatt J D, Lossos I S. IL-4 affects proliferation, chemosensitivity-and rituximab sensitivity of germinal center B-cell like (GCB) and activated B-cell like (ABC) diffuse large B-cell lymphoma differently. Blood 2004; 104: 73A

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