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Leukemia & Lymphoma Volume 58, 2017 - Issue 3
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Letters to the Editor

Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors

Katerina GemenetziInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece;
,
Chrysi GaligalidouInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece;
,
Elisavet VlachonikolaInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece;
,
Evangelia StalikaInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece; ;Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Aliki XochelliInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece; ;Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Panagiotis BaliakasDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
,
Maria KarypidouHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Tasoula TouloumenidouHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Evangelia MingaInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece;
,
Vasiliki DoukaHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Michalis IskasHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Anastasia AthanasiadouHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Antonios MakrisInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece;
,
Niki StavroyianniHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Achilles AnagnostopoulosHematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece;
,
Anastasia HadzidimitriouInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece; ;Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
&
Kostas StamatopoulosInstitute of Applied Biosciences, Center of Research and Technology Hellas, Thessaloniki, Greece; ;Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, SwedenCorrespondence[email protected]
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Pages 726-728 | Received 23 Feb 2016, Accepted 01 Jul 2016, Published online: 09 Aug 2016

References

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  • Sturm I, Bosanquet AG, Hummel M, et al. In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis. BMC Cancer. 2005;5:105.
  • Agathangelidis A, Darzentas N, Hadzidimitriou A, et al. Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies. Blood. 2012;119:4467–4475.
  • Lefranc MP, Giudicelli V, Duroux P, et al. IMGT®, the international ImMunoGeneTics information system(R) 25 years on. Nucleic Acids Res. 2014;43:D413–D422.
  • Murray F, Darzentas N, Hadzidimitriou A, et al. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. Blood. 2008;111:1524–1533.
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  • Baliakas P, Hadzidimitriou A, Sutton L, et al. Recurrent mutations refine prognosis in chronic lymphocytic leukemia. Leukemia. 2015;29:329–436.

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