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Original Articles: Clinical

Efficacy and safety of triple therapy with aprepitant, ondansetron, and prednisone for preventing nausea and vomiting induced by R-CEOP or CEOP chemotherapy regimen for non-Hodgkin lymphoma: a phase 2 open-label, randomized comparative trial

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Pages 816-821 | Received 17 May 2016, Accepted 09 Jul 2016, Published online: 22 Aug 2016

References

  • Hesketh PJ. Treatment of chemotherapy-induced emesis in the 1990s: impact of the 5-HT3 receptor antagonists. Support Care Cancer. 1994;2:286–292.
  • de Boer-Dennert M, de Wit R, Schmitz PIM, et al. Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists. Br J Cancer. 1997;76:1055–1061.
  • Passik SD, Kirsh KL, Rosenfeld B, et al. The changeable nature of patients’ fears regarding chemotherapy: implications for palliative care. J Pain Symptom Manage. 2002;21:113–120.
  • Basch E, Prestrud AA, Hesketh PJ, et al. Antiemetics: American society of clinical oncology clinical practice guideline update. J Clin Oncol. 2011;29:4189–4198.
  • National Comprehensive Cancer Network NCCN Clinical Practice Guidelines in Oncology [Internet]. Antiemesis, Version 1. 2014 [cited 2014 Dec 18]. Available from: http://www.nccn.org/professionals/physician_gls/pdf/antiemesis.
  • Warr D. Management of highly emetogenicchemotherapy. Curr Opin Oncol. 2012;24:371–375.
  • Coiffier B. Treatment of non-Hodgkin's lymphoma: a look over the past decade. Clin Lymphoma Myeloma. 2006;7:S7–S13.
  • MASCC/ESMO Antiemetic Guideline 2013 [Internet]. [cited 2014 Dec 18]. Available from: http://www.mascc.org/assets/documents/mascc_guidelines_english_2013.
  • Hesketh PJ, Grunberg SM, Gralla RJ, et al. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin—the Aprepitant Protocol 052 Study Group. J Clin Oncol. 2003;21:4112–4119.
  • Poli-Bigelli S, Rodrigues-Pereira J, Carides AD, et al. Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin America. Cancer. 2003;97:3090–3098.
  • Warr DG, Hesketh PJ, Gralla RJ, et al. Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy. J Clin Oncol. 2005;23:2822–2830.
  • Hu Z, Cheng Y, Zhang H, et al. Aprepitant triple therapy for the prevention of chemotherapy-induced nausea and vomiting following high-dosecisplatin in Chinese patients: a randomized, double-blind, placebo-controlled phase III trial. Support Care Cancer. 2014;22:979–987.
  • Health UDo, Services H. National Cancer Institute. Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0. 2013.
  • Martin AR, Pearson JD, Cai B, et al. Assessing the impact of chemotherapy-induced nausea and vomiting on patients' daily lives: a modified version of the functional living index-emesis (FLIE) with 5-day recall. Support Care Cancer. 2003;11:522–527.
  • McCrea JB, Majumdar AK, Goldberg MR, et al. Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone. Clin Pharmacol Ther. 2003;74:17–24.
  • Maie K, Okoshi Y, Takaiwa N, et al. Aprepitant does not alter prednisolone pharmacokinetics in patients treated with R-CHOP. Ann Oncol. 2014;25:298–299.
  • Olver IN. Antiemetic study methodology: recommendations for future studies. Oncology. 1996;53:96–101.
  • Rapoport BL, Jordan K, Boice JA, et al. Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad rangeof moderately emetogenic chemotherapies and tumortypes: a randomized, double-blind study. Support Care Cancer. 2010;18:423–431.
  • Yeo W, Mo FK, Suen JJ, et al. A randomized study of aprepitant, ondnsetron and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenicchemotherapy. Breast Cancer Res Treat. 2009;113:529–535.
  • Grunberg SM, Dugan M, Muss H, et al. Effectiveness of a single-day three-drug regimen of dexamethasone, palonosetron, and aprepitant for the prevention of acute and delayed nausea and vomiting caused by moderately emetogenic chemotherapy. Support Care Cancer. 2009;17:589–594.
  • Hesketh PJ, Sanz-Altamira P. Aprepitant, dexamethasone, and palonosetron in the prevention of doxorubicin/cyclophosphamide-induced nausea and vomiting. Support Care Cancer. 2012;20:653–656.
  • Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med. 2008;358:2482–2494.

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