A pediatric case of acute megakaryocytic leukemia with double chimeric transcripts of CBFA2T3-GLIS2 and DHH-RHEBL1

Kanako Mitsui-SekinakaDepartment of Pediatrics, National Defense Medical College, Saitama, Japan;

Yujin SekinakaDepartment of Pediatrics, National Defense Medical College, Saitama, Japan;

Yumi OguraDepartment of Pediatrics, National Defense Medical College, Saitama, Japan;

Mamoru HondaDepartment of Pediatrics, National Defense Medical College, Saitama, Japan;

Ryo OhyamaDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Chigusa OyamaDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Kiyotaka IsobeDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Makiko MoriDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Yuki ArakawaDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Katsuyoshi KohDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Ryoji HanadaDepartment of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan

Shigeaki NonoyamaDepartment of Pediatrics, National Defense Medical College, Saitama, Japan;

Hiroyuki KawaguchiDepartment of Pediatrics, National Defense Medical College, Saitama, Japan; Correspondence[email protected]

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References

Gruber T, Gedman AL, Zhang J, et al. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell. 2012;22:683–697.
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Masetti R, Togni M, Astolfi A, et al. DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia. Oncotarget. 2013;4:1712–1720.
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A pediatric case of acute megakaryocytic leukemia with double chimeric transcripts of CBFA2T3-GLIS2 and DHH-RHEBL1

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A pediatric case of acute megakaryocytic leukemia with double chimeric transcripts of CBFA2T3-GLIS2 and DHH-RHEBL1

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