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Leukemia & Lymphoma Volume 60, 2019 - Issue 5
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Original Article

R-CHOP without radiation in frontline management of primary mediastinal B-cell lymphoma

Marcus MessmerDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Hua-Ling TsaiDivision of Biostatistics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Ravi VaradhanDivision of Biostatistics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Lode J. SwinnenDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Richard J. JonesDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Richard F. AmbinderDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Satish P. ShanbhagDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; View further author information
,
Michael J. BorowitzDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USAView further author information
&
Nina Wagner-JohnstonDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Correspondence[email protected]
View further author information
 show all
Pages 1261-1265 | Received 13 Apr 2018, Accepted 26 Aug 2018, Published online: 18 Jan 2019

References

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  • Zinzani PL, Stefoni V, Finolezzi E, et al. Rituximab combined with MACOP-B or VACOP-B and radiation therapy in primary mediastinal large B-cell lymphoma: a retrospective study. Clin Lymphoma Myeloma. 2009;9:381–385.
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  • Soumerai JD, Hellmann MD, Feng Y, et al. Treatment of primary mediastinal B-cell lymphoma with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone is associated with a high rate of primary refractory disease. Leuk Lymphoma. 2014;55:538–543.
  • Shah NN, Szabo A, Huntington SF, et al. R-CHOP versus dose-adjusted R-EPOCH in frontline management of primary mediastinal B-cell lymphoma: a multi-centre analysis. Br J Haematol. 2018;180:534–544.
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  • Giulino-Roth L, O'Donohue T, Chen Z, et al. Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R. Br J Haematol. 2017;179:739–747.
  • Moskowitz CH, Schoder H, Teruya-Feldstein J, et al. Risk-adapted dose-dense immunochemotherapy determined by interim FDG-PET in advanced-stage diffuse large B-cell lymphoma. Jco. 2010;28:1896–1903.

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