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Leukemia & Lymphoma Volume 61, 2020 - Issue 7
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Letters to the Editor

Longitudinal clonal architecture of acute myeloid leukemia with NPM1 driver insertion, early TET2 mutations and secondary e6a2 BCR-ABL1 rearrangement

Maria Pilar Gallego HernanzCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France;
,
Nathalie SorelCHU de Poitiers, Service de Cancérologie Biologique, Poitiers, France;
,
Sabrina BouyerCHU de Poitiers, Service d’Hématologie Biologique, Poitiers, France
,
Deborah DesmierCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France;
,
Mélanie CholletCHU de Poitiers, Service d’Hématologie Biologique, Poitiers, France
,
Natacha MaillardCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France;
,
Françoise BrizardCHU de Poitiers, Service d’Hématologie Biologique, Poitiers, France
,
Niels MoyaCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France;
,
Jose Miguel Torregrosa DiazCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France;
,
Xavier LeleuCHU de Poitiers, Service d’Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France; ;INSERM, CIC-P 1402, Poitiers, France; ORCID Iconhttp://orcid.org/0000-0002-9822-4170
ORCID Icon &
Jean-Claude ChomelCHU de Poitiers, Service de Cancérologie Biologique, Poitiers, France; Correspondence[email protected]
 show all
Pages 1709-1713 | Received 19 Nov 2019, Accepted 01 Feb 2020, Published online: 20 Feb 2020

References

  • Metzeler KH, Herold T, Rothenberg-Thurley M, et al. Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia. Blood. 2016;128(5):686–698.
  • Tyner JW, Tognon CE, Bottomly D, et al. Functional genomic landscape of acute myeloid leukaemia. Nature. 2018;562(7728):526–531.
  • Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med. 2005;352(3):254–266.
  • Neuendorff NR, Burmeister T, Dörken B, et al. BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features. Ann Hematol. 2016;95(8):1211–1221.
  • Kurt H, Zheng L, Kantarjian HM, et al. Secondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome. Mod Pathol. 2018;31(7):1141–1154.
  • Konoplev S, Yin CC, Kornblau SM, et al. Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia. Leuk Lymphoma. 2013;54(1):138–144.
  • Grossmann V, Kohlmann A, Zenger M, et al. A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases. Leukemia. 2011;25(3):557–560.
  • Potter N, Miraki-Moud F, Ermini L, et al. Single cell analysis of clonal architecture in acute myeloid leukaemia. Leukemia. 2019;33(5):1113–1123.
  • Busque L, Buscarlet M, Mollica L, et al. Concise review: age-related clonal hematopoiesis: stem cells tempting the devil. Stem Cells. 2018;36(9):1287–1294.
  • Bowman RL, Busque L, Levine RL. Clonal hematopoiesis and evolution to hematopoietic malignancies. Cell Stem Cell. 2018;22(2):157–170.
  • Valent P, Kern W, Hoermann G, et al. Clonal hematopoiesis with oncogenic potential (CHOP): separation from CHIP and roads to AML. Int J Mol Sci. 2019;20(3):789.
  • Bacher U, Haferlach T, Alpermann T, et al. Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations. Br J Haematol. 2011;152(6):713–720.
  • Piedimonte M, Ottone T, Alfonso V, et al. A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review. BMC Cancer. 2019;19(1):50.
  • Baccarani M, Castagnetti F, Gugliotta G, Rosti G, Soverini S, Albeer A, for the International BCR-ABL Study Group, et al. The proportion of different BCR-ABL1 transcript types in chronic myeloid leukemia. An international overview. Leukemia. 2019;33(5):1173–1183.
  • Ding L, Ley TJ, Larson DE, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012;481(7382):506–510.

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