Impact of intensifying primary antibiotic prophylaxis in at-home autologous stem cell transplantation program for lymphoma patients

References

• Sureda A, Bader P, Cesaro S, et al. Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015. Bone Marrow Transplant. 2015;50(8):1037–1056.
   PubMed Web of Science ®Google Scholar
• Majhail NS, Farnia SH, Carpenter PA, et al. Indications for autologous and allogeneic hematopoietic cell transplantation: guidelines from the American Society for Blood and Marrow Transplantation. Biol Blood Marrow Transplant. 2015;21(11):1863–1869.
   PubMed Web of Science ®Google Scholar
• Klumpp TR, Mangan KF, Goldberg SL, et al. Granulocyte colony-stimulating factor accelerates neutrophil engraftment following peripheral-blood stem-cell transplantation: a prospective, randomized trial. J Clin Oncol. 1995;13(6):1323–1327.
   PubMed Web of Science ®Google Scholar
• Jantunen E, Itälä M, Lehtinen T, et al. Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients. Eur J Haematol. 2006;76(3):245–250.
   PubMed Web of Science ®Google Scholar
• Piñana JL, Montesinos P, Martino R, et al. Incidence, risk factors, and outcome of bacteremia following autologous hematopoietic stem cell transplantation in 720 adult patients. Ann Hematol. 2014;93(2):299–307.
   PubMed Web of Science ®Google Scholar
• Martino M, Lemoli RM, Girmenia C, et al. Italian consensus conference for the outpatient autologous stem cell transplantation management in multiple myeloma. Bone Marrow Transplant. 2016;51(8):1032–1040.
   PubMed Web of Science ®Google Scholar
• Fernández-Avilés F, Carreras E, Urbano-Ispizua A, et al. Case-control comparison of at-home to total hospital care for autologous stem-cell transplantation for hematologic malignancies. J Clin Oncol. 2006;24(30):4855–4861.
   PubMed Web of Science ®Google Scholar
• Faucher C, Le Corroller Soriano AG, Esterni B, et al. Randomized study of early hospital discharge following autologous blood SCT: medical outcomes and hospital costs. Bone Marrow Transplant. 2012;47(4):549–555.
   PubMed Web of Science ®Google Scholar
• Holbro A, Ahmad I, Cohen S, et al. Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma. Biol Blood Marrow Transplant. 2013;19(4):547–551.
   PubMed Web of Science ®Google Scholar
• Graff TM, Singavi AK, Schmidt W, et al. Safety of outpatient autologous hematopoietic cell transplantation for multiple myeloma and lymphoma. Bone Marrow Transplant. 2015;50(7):947–953.
   PubMed Web of Science ®Google Scholar
• Lisenko K, Sauer S, Bruckner T, et al. High-dose chemotherapy and autologous stem cell transplantation of patients with multiple myeloma in an outpatient setting. BMC Cancer. 2017;17(1):151.
   PubMed Web of Science ®Google Scholar
• Solano C, Gutierrez A, Martinez F, et al. Prophylaxis of early bacterial infections after autologous peripheral blood stem cell transplantation (PBSCT): a matched-pair study comparing oral fluoroquinolones and intravenous piperacillin-tazobactam. Bone Marrow Transplant. 2005;36(1):59–65.
   PubMed Web of Science ®Google Scholar
• Slavin MA, Grigg AP, Schwarer AP, et al. A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007;40(2):157–163.
   PubMed Web of Science ®Google Scholar
• Gil L, Styczynski J, Komarnicki M. Infectious complication in 314 patients after high-dose therapy and autologous hematopoietic stem cell transplantation: risk factors analysis and outcome. Infection. 2007;35(6):421–427.
   PubMed Web of Science ®Google Scholar
• Eleutherakis-Papaiakovou E, Kostis E, Migkou M, et al. Prophylactic antibiotics for the prevention of neutropenic fever in patients undergoing autologous stem-cell transplantation: results of a single institution, randomized phase 2 trial. Am J Hematol. 2010;85(11):863–867.
   PubMed Web of Science ®Google Scholar
• Satlin MJ, Vardhana S, Soave R, et al. Impact of prophylactic levofloxacin on rates of bloodstream infection and fever in neutropenic patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2015;21(10):1808–1814.
   PubMed Web of Science ®Google Scholar
• Tomblyn M, Chiller T, Einsele H, et al. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant. 2009;15(10):1143–1238.
   PubMed Web of Science ®Google Scholar
• Freifeld AG, Bow EJ, Sepkowitz KA, et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America. Clin Infect Dis. 2011;52(4):e56–93.
   PubMed Web of Science ®Google Scholar
• Reuter S, Kern WV, Sigge A, et al. Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies. Clin Infect Dis. 2005;40(8):1087–1093.
   PubMed Web of Science ®Google Scholar
• Horváthová Z, Ŝpánik S, Ŝufliarsky J, et al. Bacteremia due to methicillin-resistant Staphylococci occurs more frequently in neutropenic patients who received antimicrobial prophylaxis and is associated with higher mortality in comparison to methicillin-sensitive bacteriemia. Int J Antimicrob Agents. 1998;10(1):55–58.
   PubMed Web of Science ®Google Scholar
• Kroschinsky F, Wichmann G, Bornhauser M, et al. Efficacy and tolerability of prophylactic treatment with intravenous piperacillin/tazobactam in patients undergoing hematopoietic stem cell transplantation. Transplant Infect Dis. 2002;4(3):132–136.
   PubMedGoogle Scholar
• Delgado J, Pereira A, Villamor N, et al. Survival analysis in hematologic malignancies: recommendations for clinicians. Haematologica. 2014;99(9):1410–1420.
   PubMed Web of Science ®Google Scholar
• Buzyn A, Tancrède C, Nitenberg G, et al. Reflections on gut decontamination in hematology. Clin Microbiol Infect. 1999;5(8):449–456.
   PubMedGoogle Scholar
• Berro M, Arbelbide JA, Rivas MM, et al. Hematopoietic Cell Transplantation-Specific Comorbidity Index predicts morbidity and mortality in autologous stem cell transplantation. Biol Blood Marrow Transplant. 2017;23(10):1646–1650.
   PubMed Web of Science ®Google Scholar
• Kim JH, Goulston C, Zangari M, et al. Impact of a change in antibacterial prophylaxis on bacteremia and hospitalization rates following outpatient autologous peripheral blood stem cell transplantation for multiple myeloma. Transpl Infect Dis. 2014;16(3):421–429.
   PubMed Web of Science ®Google Scholar
• van der Velden W, Blijlevens NMA, Feuth T, et al. Febrile mucositis in haematopoietic SCT recipients. Bone Marrow Transplant. 2009;43(1):55–60.
   PubMed Web of Science ®Google Scholar
• Blijlevens N, Schwenkglenks M, Bacon P, et al. Prospective oral mucositis audit: oral mucositis in patients receiving high-dose melphalan or BEAM conditioning chemotherapy-European Blood and Marrow Transplantation Mucositis Advisory Group. J Clin Oncol. 2008;26(9):1519–1525.
   PubMed Web of Science ®Google Scholar
• Marchesi F, Tendas A, Giannarelli D, et al. Cryotherapy reduces oral mucositis and febrile episodes in myeloma patients treated with high-dose melphalan and autologous stem cell transplant: a prospective, randomized study. Bone Marrow Transplant. 2017;52(1):154–156.
   PubMed Web of Science ®Google Scholar
• Gutiérrez-García G, Rovira M, Magnano L, et al. Innovate strategies minimize engraftment syndrome in multiple myeloma patients with novel induction therapy following autologous hematopoietic stem cell transplantation. Bone Marrow Transplant. 2018;53(12):1541–1547.
   PubMed Web of Science ®Google Scholar
• Osakabe L, Utsumi A, Saito B, et al. Influence of oral anaerobic bacteria on hematopoietic stem cell transplantation patients: oral mucositis and general condition. Transplant Proc. 2017;49(9):2176–2182.
   PubMed Web of Science ®Google Scholar
• Worthington HV, Clarkson JE, Bryan G, et al. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2011;(4):CD000978. DOI:10.1002/14651858.CD000978.pub5
   PubMed Web of Science ®Google Scholar