The prognostic implications of tetraploidy/near-Tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature

References

• McGowan-Jordan J, Simons A, Schmid M. ISCN: an international system for human cytogenomic nomenclature (2016). Basel, Switzerland; New York: Karger; 2016.
   Google Scholar
• Pui CH, Carroll AJ, Head D, et al. Near-triploid and near-tetraploid acute lymphoblastic leukemia of childhood. Blood. 1990;76(3):590–596.
   PubMed Web of Science ®Google Scholar
• Khan AM, Munir A, Asrani R, et al. Acute myeloid leukemia with philadelphia chromosome, near-tetraploidy, and 5q deletion. Cureus. 2019;11(9):e5606.
   PubMed Web of Science ®Google Scholar
• Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–447.
   PubMed Web of Science ®Google Scholar
• Pang CS, Pettenati MJ, Pardee TS. Clinicopathological analysis of near-tetraploidy/tetraploidy acute myeloid leukaemia. J Clin Pathol. 2015;68(3):236–240.
   PubMed Web of Science ®Google Scholar
• Yang R, Jiang M, Zhao J, et al. Identification of chromosomal abnormalities and genomic features in near-triploidy/tetraploidy-acute leukemia by fluorescence in situ hybridization. Cancer Manag Res. 2019;11:1559–1567.
   PubMed Web of Science ®Google Scholar
• Lazarevic V, Rosso A, Juliusson G, et al. Prognostic significance of high hyperdiploid and triploid/tetraploid adult acute myeloid leukemia. Am J Hematol. 2015;90(9):800–805.
   PubMed Web of Science ®Google Scholar
• Huang L, Wang SA, DiNardo C, et al. Tetraploidy/near-tetraploidy acute myeloid leukemia. Leuk Res. 2017;53:20–27.
   PubMed Web of Science ®Google Scholar
• Iyer RV, Sait SNJ, Matsui S-I, et al. Massive hyperdiploidy and tetraploidy in acute myelocytic leukemia and myelodysplastic syndrome. Cancer Genet Cytogenet. 2004;148(1):29–34.
   PubMedGoogle Scholar
• Xue Y, He J, Wang Y, et al. Secondary near-pentaploidy and/or near-tetraploidy characterized by the duplication of 8;21 translocation in the M2 subtype of acute myeloid leukemia. Int J Hematol. 2000;71(4):359–365.
   PubMed Web of Science ®Google Scholar
• Xiao Z, Liu S, Liu X, et al. Tetraploidy or near-tetraploidy clones with double 8;21 translocation: a non-random additional anomaly of acute myeloid leukemia with t(8;21)(q22;q22). Haematologica. 2005;90(3):413–414.
   PubMed Web of Science ®Google Scholar
• Testa JR, Oguma N, Pollak A, et al. Near-tetraploid clones in acute leukemia. Blood. 1983;61(1):71–78.
   PubMed Web of Science ®Google Scholar
• Abe R, Raza A, Preisler HD, et al. Chromosomes and causation of human cancer and leukemia. LIV. Near-tetraploidy in acute leukemia. Cancer Genet Cytogenet. 1985;14(1–2):45–59.
   PubMedGoogle Scholar
• Xue Y, Pan Y, Liu Z, et al. Tetraploid or near-tetraploid clones characterized by two 8;21 translocations and other chromosomal abnormalities in two patients with acute myeloblastic leukemia. Cancer Genet Cytogenet. 1996;92(1):18–23.
   PubMedGoogle Scholar
• Yamamoto K, Nagata K, Kida A, et al. CD7+ near-tetraploid acute myeloblastic leukemia M2 with double t(8;21)(q22;q22) translocations and Aml1/ETO rearrangements detected by fluorescence in situ hybridization analysis. Int J Hematol. 2001;74(3):316–321.
   PubMed Web of Science ®Google Scholar
• Li L, Li J, Li G, et al. A tetraploid minimally differentiated acute myeloblastic leukemia with extensive erythrophagocytosis: a case report and literature review. Int J Hematol. 2012;96(6):801–805.
   PubMed Web of Science ®Google Scholar
• Yeh SP, Wang Y, Su J, et al. Near-tetraploid minimally differentiated acute myeloid leukemia with extensive erythrophagocytosis by leukemic blasts. Ann Hematol. 2000;79(1):36–39.
   PubMed Web of Science ®Google Scholar
• Sharma M, Dayama A, Jain S, et al. AML associated with extensive erythrophagocytosis and tetraploidy. Eur J Haematol. 2011;87(3):286.
   PubMed Web of Science ®Google Scholar
• Bene MC, Castoldi G, Derolf A, et al. Near-tetraploid acute myeloid leukemias: an EGIL retrospective study of 25 cases. Leukemia. 2006;20(4):725–728.
   PubMed Web of Science ®Google Scholar
• Watanabe A, Inokuchi K, Yamaguchi H, et al. Near-triploidy and near-tetraploidy in hematological malignancies and mutation of the p53 gene. Clin Lab Haematol. 2004;26(1):25–30.
   PubMedGoogle Scholar
• Lemez P, Zemanová Z, Marinov I, et al. Unusually long survival of a 67-year-old patient with near-tetraploid acute myeloid leukemia m0 without erythroblastic and megakaryocytic dysplasia. Acta Haematol. 2011;126(3):129–134.
   PubMed Web of Science ®Google Scholar
• Lemez P, Michalová K, Zemanová Z, et al. Three cases of near-tetraploid acute myeloid leukemias originating in pluripotent myeloid progenitors. Leuk Res. 1998;22(7):581–588.
   PubMed Web of Science ®Google Scholar
• Zelante L, Perla G, Bodenizza C, et al. Tetraploidy (92,XXYY) in an acute nonlymphocytic leukemia (M1) patient following autologous bone marrow transplantation. Cancer Genet Cytogenet. 1988;36(1):69–75.
   PubMedGoogle Scholar
• Trujillo JM, Cork A, Drewinko B, et al. Case report: tetraploid leukemia. Blood. 1971;38(5):632–637.
   PubMed Web of Science ®Google Scholar
• Yamaguchi H, Inokuchi K, Yokomizo E, et al. Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy. Int J Hematol. 2002;75(1):63–66.
   PubMed Web of Science ®Google Scholar
• Jurisic V, Pavlović S, Colović N, et al. Single institute study of FLT3 mutation in acute myeloid leukemia with near tetraploidy in Serbia. J Genet. 2009;88(2):149–152.
   PubMed Web of Science ®Google Scholar
• Jarosova M, Nedomova R, Hubacek J, et al. Rare tetraploidy with large 5q deletion in acute myeloid leukemia with myelodysplasia-related changes (AML-MRC). Leuk Res. 2012;36(4):e68.
   PubMed Web of Science ®Google Scholar
• Clarke MR, Lynch EF, Contis LC, et al. Near-tetraploidy in adult acute myelogenous leukemia. Cancer Genet Cytogenet. 1996;86(2):107–115.
   PubMedGoogle Scholar
• Gundimeda SD, Ahmed F, Mundada MC, et al. A near tetraploid clone in acute myeloid leukemia with CD56 expression. J Cancer Res Ther. 2014;10(1):187–190.
   PubMed Web of Science ®Google Scholar
• Zhang JH, Zheng YC, Wang YX, et al. Laboratory study on near-tetraploid acute myelogenous leukemia of childhood. Zhongguo Dang Dai Er Ke Za Zhi. 2009;11(4):263–266.
   PubMedGoogle Scholar
• Rohon P, Nedomova R, Prekopova I, et al. Acute myeloid leukemia with minimal differentiation: unusual cytogenetics, morphology, phenotype and clinical course. Leuk Res. 2012;36(7):e133.
   PubMed Web of Science ®Google Scholar
• Wafa A, ALmedania S, Aljapawe A, et al. A new adult AML case with an extremely complex karyotype, remission and relapse combined with high hyperdiploidy of a normal chromosome set in secondary AML. BMC Hematol. 2018;18:21.
   PubMedGoogle Scholar
• Takahashi T, Ishiguro K, Maruyama Y, et al. Near tetraploidy acute myeloid leukemia in long-term remission with persistent clonal hematopoiesis with del(20)(q12q13). Intern Med, 2017.
   Google Scholar
• Vanegas YAM, Azzouqa A-GM, Menke DM, et al. Myelodysplasia-related acute myeloid leukemia and acute promyelocytic leukemia: concomitant occurrence of two molecularly distinct diseases. Hematol Rep. 2018;10(3):7658.
   PubMed Web of Science ®Google Scholar
• Vilches AS, de Bustamante AD, Sanchez-Calero J, et al. Tetraploidy acute myeloid leukaemia after chromosome 16 inversion. BMJ Case Rep. 2017;2017:bcr2017219274.
   PubMedGoogle Scholar
• Garson OM. Acute non-lymphocytic leukaemia. Clin Haematol. 1980;9(1):39–54.
   PubMedGoogle Scholar
• Lemez P, Jelínek J, Michalová K, et al. Near-tetraploid poorly differentiated acute myeloid leukemia M0 diagnosed by short-term cultures with a phorbol ester TPA. Leuk Res. 1994;18(7):493–497.
   PubMed Web of Science ®Google Scholar
• Byrd JC. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood. 2002;100(13):4325–4336.
   PubMed Web of Science ®Google Scholar
• Cheung E, Perissinotti AJ, Bixby DL, et al. The leukemia strikes back: a review of pathogenesis and treatment of secondary AML. Ann Hematol. 2019;98(3):541–559.
   PubMed Web of Science ®Google Scholar
• Eisfeld A-K, Kohlschmidt J, Mrózek K, et al. Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies. Leukemia. 2018;32(6):1338–1348.
   PubMed Web of Science ®Google Scholar
• Herold T, Rothenberg-Thurley M, Grunwald VV, et al. Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia. Leukemia. 2020. DOI:https://doi.org/10.1038/s41375-020-0806-0
   Google Scholar
• Harada Y, Nagata Y, Kihara R, et al. Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study. Leuk Res. 2018;66:20–27.
   PubMed Web of Science ®Google Scholar
• Othus M, Estey EH, Garcia-Manero G, et al. Second cycle remission achievement with 7 + 3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials. Leukemia. 2019;33(2):554–558.
   PubMed Web of Science ®Google Scholar