https://orcid.org/0000-0002-7368-2247
References
- Nakamura T, Largaespada DA, Lee MP, et al. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet. 1996;12(2):154–158.
- Kabachinski G, Schwartz TU. The nuclear pore complex-structure and function at a glance. J Cell Sci. 2015;128(3):423–429.
- Romana SP, Radford-Weiss I, Ben Abdelali R, et al. NUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique. Leukemia. 2006;20(4):696–706.
- Struski S, Lagarde S, Bories P, et al. NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis. Leukemia. 2017;31(3):565–572.
- Michmerhuizen NL, Klco JM, Mullighan CG. Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies. Blood. 2020;136(20):2275–2289.
- Gough SM, Slape CI, Aplan PD. NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood. 2011;118(24):6247–6257.
- Kasper LH, Brindle PK, Schnabel CA, et al. CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity. Mol Cell Biol. 1999;19(1):764–776.
- Jankovic D, Gorello P, Liu T, et al. Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia. Blood. 2008;111(12):5672–5682.
- Paz H, Lynch MR, Bogue CW, et al. The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis. Blood. 2010;116(8):1254–1262.
- Takeda R, Asada S, Park S-J, et al. HHEX promotes myeloid transformation in cooperation with mutant ASXL1. Blood. 2020;136(14):1670–1684.
- Lahortiga I, Vizmanos JL, Agirre X, et al. NUP98 is fused to adducin 3 in a patient with T-cell acute lymphoblastic leukemia and myeloid markers, with a new translocation t(10;11)(q25;p15). Cancer Res. 2003;63(12):3079–3083.
- Takeda A, Goolsby C, Yaseen NR. NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells. Cancer Res. 2006;66(13):6628–6637.
- Hollink IHIM, van den Heuvel-Eibrink MM, Arentsen-Peters S, et al. NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern. Blood. 2011;118(13):3645–3656.
- Mercher T, Schwaller J. Pediatric acute myeloid leukemia (AML): from genes to models toward targeted therapeutic intervention. Front Pediatr. 2019;7:401.
- de Rooij JDE, van den Heuvel-Eibrink MM, Hermkens MCH, et al. BCOR and BCORL1 mutations in pediatric acute myeloid leukemia. Haematologica. 2015;100(5):e194–e195.