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Leukemia & Lymphoma Volume 63, 2022 - Issue 7
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Letters to Editor

Tagraxofusp as first-line treatment for blastic plasmacytoid dendritic cell neoplasm

Rocío Díaz Acedoa Pharmacy Service, Hospital de Valme, Sevilla, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7186-0572
ORCID Icon,
María Ángeles Domínguez Muñozb Hematology Service, Hospital de Valme, Sevilla, Spain
,
Clara Navajas Lagunab Hematology Service, Hospital de Valme, Sevilla, Spain
,
Rosario Morales Camachoc Hematology Service, Hospital Virgen del Rocío, Sevilla, Spain
,
Isabel Simón Pilob Hematology Service, Hospital de Valme, Sevilla, Spain
,
Virgilio Pablo Calama Ruiz-Mateosb Hematology Service, Hospital de Valme, Sevilla, Spain
,
Manuel Yébenes Ramírezb Hematology Service, Hospital de Valme, Sevilla, Spain
,
María Vahí Sánchez de Medinab Hematology Service, Hospital de Valme, Sevilla, Spain
,
Silvia Artacho Criadoa Pharmacy Service, Hospital de Valme, Sevilla, Spain
,
Aitana Rodríguez Péreza Pharmacy Service, Hospital de Valme, Sevilla, Spain
&
María Carmen Couto Carob Hematology Service, Hospital de Valme, Sevilla, Spain
 show all
Pages 1762-1764 | Received 28 Aug 2021, Accepted 03 Feb 2022, Published online: 24 Feb 2022

References

  • Pemmaraju N, Lane AA, Sweet KL, et al. Tagraxofusp in blastic plasmacytoid Dendritic-Cell neoplasm. N Engl J Med. 2019;380(17):1628–1637.
  • Beziat G, Ysebaert L. Tagraxofusp for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN): a brief report on emerging data. Onco Targets Ther. 2020;13:5199–5205.
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  • Roos-Weil D, Dietrich S, Boumendil A, European Group for Blood and Marrow Transplantation Lymphoma, Pediatric Diseases, and Acute Leukemia Working Parties, et al. Stem cell transplantation can provide durable disease control in blastic plasmacytoid dendritic cell neoplasm: a retrospective study from the European group for blood and marrow transplantation. Blood. 2013;121(3):440–446.
  • Aoki T, Suzuki R, Kuwatsuka Y, et al. Long-term survival following autologous and allogeneic stem cell transplantation for blastic plasmacytoid dendritic cell neoplasm. Blood. 2015;125(23):3559–3562.
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  • Jen EY, Gao X, Li L, et al. FDA approval summary: tagraxofusp-erzs for treatment of blastic plasmacytoid dendritic cell neoplasm. Clin Cancer Res. 2020;26(3):532–536.
  • Committee for Medicinal Products for Human Use. European Medicines Agency. Assessment report: Elzonris. [Consulted on 6th June 2021. Available on: https://www.ema.europa.eu/en/medicines/human/EPAR/elzonris.
  • Wilson NR, Konopleva M, Khoury JD, et al. Novel therapeutic approaches in blastic plasmacytoid dendritic cell neoplasm (BPDCN): era of targeted therapy. Clin Lymphoma Myeloma Leuk. 2021;21(11):734–740.
  • DiPippo AJ, Nr W, Pemmaraju N. Targeting CD123 in BPDCN: an emerging field. Expert Rev Hematol. 2021;14(11):993–1004.
  • Martín-Martín L, Almeida J, Pomares H, et al. Blastic plasmacytoid dendritic cell neoplasm frequently shows occult Central nervous system involvement at diagnosis and benefits from intrathecal therapy. Oncotarget. 2016;7(9):10174–10181.
  • Pemmaraju N, Wilson NR, Khoury JD, et al. Central nervous system involvement in blastic plasmacytoid dendritic cell neoplasm. Blood. 2021;138(15):1373–1377.

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