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Original Articles

Comorbidity burden and outcomes of older adults with acute promyelocytic leukemia: a National Cancer Database analysis of 2221 patients

ORCID Icon, , ORCID Icon, , ORCID Icon, & show all
Pages 691-697 | Received 02 Oct 2022, Accepted 31 Dec 2022, Published online: 11 Jan 2023

References

  • Lehmann S, Ravn A, Carlsson L, et al. Continuing high early death rate in acute promyelocytic leukemia: a population-based report from the Swedish Adult Acute Leukemia Registry. Leukemia. 2011;25(7):1128–1134.
  • Park JH, Qiao B, Panageas KS, et al. Early death rate in acute promyelocytic leukemia remains high despite all-trans retinoic acid. Blood. 2011;118(5):1248–1254.
  • Chen Y, Kantarjian H, Wang H, et al. Acute promyelocytic leukemia: a population‐based study on incidence and survival in the United States, 1975–2008. Cancer. 2012;118(23):5811–5818.
  • Dores GM, Devesa SS, Curtis RE, et al. Acute leukemia incidence and patient survival among children and adults in the United States, 2001–2007. Blood. 2012;119(1):34–43.
  • Dhakal P, Lyden E, Rajasurya V, et al. Early mortality and overall survival in acute promyelocytic leukemia: do real-world data match results of the clinical trials? Leuk Lymphoma. 2021;62(8):1949–1957.
  • Ono T, Takeshita A, Kishimoto Y, et al. Long-term outcome and prognostic factors of elderly patients with acute promyelocytic leukemia. Cancer Sci. 2012;103(11):1974–1978.
  • Dhakal P, Shostrom V, Al-Kadhimi ZS, et al. Usefulness of Charlson comorbidity index to predict early mortality and overall survival in older patients with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2020;20(12):804.e8–812.e8.
  • Lo-Coco F, Avvisati G, Vignetti M, et al. Retinoic acid and arsenic trioxide for acute promyelocytic leukemia. N Engl J Med. 2013;369(2):111–121.
  • Iland HJ, Bradstock K, Supple SG, et al. All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4). Blood. 2012;120(8):1570–1580; [quiz 1752].
  • Kayser S, Rahmé R, Martínez-Cuadrón D, et al. Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an international collaborative study. Leukemia. 2020;34(9):2333–2341.
  • Debragga S, Simon KS, Kharkhanis P, et al. Comorbid conditions in newly diagnosed patients with acute promyelocytic leukemia (APL) in “real world” patients; decreased induction mortality despite a high comorbid index. Blood. 2017;130:3379.
  • Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–619.
  • About the National Cancer Database; 2017 [cited 2020 Nov 6]. Available from: https://www.facs.org/quality-programs/cancer/ncdb/about
  • Bhatt VR, Shostrom V, Armitage JO, et al. Treatment patterns and outcomes of octogenarian patients with acute myeloid leukemia. Am J Hematol. 2019;94(6):E169–E172.
  • Latagliata R, Breccia M, Fazi P, et al. Long-term results of the GIMEMA LAP AIDA 0493 amended protocol in elderly patients with acute promyelocytic leukemia (APL). Blood. 2005;106:885.
  • Salamero O, Martínez-Cuadrón D, Sobas M, et al. Real life outcomes of patients aged ≥75 years old with acute promyelocytic leukemia: experience of the PETHEMA registry. Leuk Lymphoma. 2019;60(11):2720–2732.
  • Klepin HD, Neuendorff NR, Larson RA, et al. Treatment of acute promyelocytic leukemia in older patients: recommendations of an international society of geriatric oncology (SIOG) task force. J Geriatr Oncol. 2020;11(8):1199–1209.

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