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Leukemia & Lymphoma Volume 64, 2023 - Issue 3
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Letters to the Editor

Prognostic significance of blast immunophenotype on first post-induction bone marrow biopsy

Konstantinos Lontosa UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA;b Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0216-3818View further author information
ORCID Icon,
Anastasia Tsagiannia UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Mounzer Aghaa UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Anastasios Raptisa UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Jing-Zhou Houa UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Rafic Faraha UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Robert L. Rednera UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Annie Ima UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Kathleen A. Dorritiea UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Alison Sehgala UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAORCID Iconhttps://orcid.org/0000-0003-3954-7401View further author information
ORCID Icon,
James Rossettia UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Nidhi Aggarwalc Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USAView further author information
,
Melissa Sauld Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USAView further author information
,
Michael Boyiadzisa UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USAView further author information
&
Nathanael G. Baileyc Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USAORCID Iconhttps://orcid.org/0000-0002-6747-680XView further author information
ORCID Icon show all
Pages 750-752 | Received 25 Sep 2022, Accepted 21 Jan 2023, Published online: 01 Feb 2023

References

  • Dohner H, Weisdorf DJ, Bloomfield CD. Acute Myeloid leukemia. N Engl J Med. 2015;373(12):1136–1152.
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  • NCCN Guidelines. Acute myeloid leukemia. Version 2. 2022. https://www.nccn.org/professionals/physician_gls/pdf/aml.pdf.
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  • Chen X, Othus M, Wood BL, et al. Flow cytometric demonstration of decrease in bone marrow leukemic blasts after 'day 14' without further therapy in acute myeloid leukemia. Leuk Lymphoma. 2017;58(11):2717–2719.
  • Kohnke T, Bucklein V, Rechkemmer S, et al. Response assessment in acute myeloid leukemia by flow cytometry supersedes cytomorphology at time of aplasia, amends cases without molecular residual disease marker and serves as an independent prognostic marker at time of aplasia and post-induction. Haematologica. 2019;104(11):e510–e513.
  • Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–447.
  • Frisch A, Aumann S, Zuckerman T, et al. Re-induction versus salvage for D14-resiudal acute myeloid leukemia: a retrospective multi-center study. Leuk Res. 2022;119:106902.

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