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Original Articles

Derivation of an Occupational Exposure Limit (OEL) for n-Propyl Bromide Using an Improved Methodology

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Pages 711-716 | Published online: 30 Nov 2010

  • Budavari , S. , ed. 1989 . The Merck Index, , 11th ed. , Rahway, NJ : Merck and Co., Inc. .
  • Weast , R.C. , ed. 1973 . CRC Handbook of Chemistry and Physics. , 56th ed. , C-440 Cleveland, OH : CRC Press Inc .
  • Clayton , G.D. and Clayton , P.E. , eds. 1994 . Patty's Industrial Hygiene and Toxicology, , 4th ed. , 4154 New York : John Wiley and Sons, Inc. .
  • 1997 . Institut National de L'Environment Industrial et des Resques , Final Report (INERIS-L.E.T.E. Study Number 95-122 INERIS) Vemeuil-Halatte, , France : Laboratoire d'etudes de Toxicologie Experimentale . sponsored by ELF Autochem S.A. Available from the USEPA Docket A-91-42 Document X-A-13, conducted at INERIS, Parc Technologique ALATA, F-60550
  • Centre International de Toxicologie . 1993 . Acute Oral Toxicity in Rats (Laboratory Study Number 1061 1 TAR). Miserey, 27005 Evreux , USEPA Docket A-91-42 Document X-A-7 France Sponsored by Elf Autochem. Available from the
  • Centre International de Toxicologie . 1995 . Acute Dermal Toxicity in Rats (Laboratory Study Number 13113 TAR). Miserey, 27005 Evreux , USEPA Docket A-91-42 Document X-A. 10 France Sponsored by Elf Autochem. Available from the
  • ACGIH . 2000 . Ethyl Bromide, TLV-Documentation , Cincinnati, OH : ACGIH .
  • ACGIH . 2000 . Methyl Bromide. TLV-Documentation , Cincinnati, OH : ACGIH .
  • Clintrials Biorecherches . 1997 . A 28-day Inhalation Study of a Vapor Formulation of ALBTA1 in the Albino Rat , Bio-Research Project No. 91189 Quebec, , Canada : Senneville . H9X 3R3. Sponsored by Albermarle Corporation. Available from the USEPA Docket A-91-42 Document X-A-4
  • Clintrials Biorecherches . 1997 . A 13-week Inhalation Study of a Vapor Formulation of ALBTA1 in the Albino Rat , Bio-Research Project No. 91190 Quebec, , Canada : Senneville . H9X 3R3. Sponsored by Albermarle Corporation. Available from the USEPA Docket A-91-42 Document X-A-5
  • Ichihara , G. , Yu , X. Kitoh , J. 2000 . Reproductive Toxicity of 1-Bromopropane. a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats . Tox Sci , 54 : 416 – 423 .
  • Ichihara , G. , Kitoh , J. Yu , X. 2000 . 1-Bromopropane, an Alternative to Ozone Depleting Solvents . Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Studies, Tox Sci , 55 : 116 – 123 .
  • Hurtt , M.A. and Working , P.K. 1988 . Evaluation of Spermatogenesis and Sperm Quality in the Rat Following Acute Inhalation Exposure to Methyl Bromide . Fund Appl Toxicol , 10 : 490 – 498 .
  • 1992 . National Toxicology Project (NTP), Toxicology and Carcinogenesis Studies of Methyl Bromide in B6C3F1 Mice , NIH Publication No. 92-2840 Research Triangle Park, NC : National Institute of Environmental Health Sciences . NTPTR 385
  • 1989 . National Toxicology Project (NTP), Toxicology and Carcinogenesis Studies of Bromoethane (Ethyl Bromide) in F344/N Rats and B6C3F1 Mice , NIH Publication No. 90-2818 Research Triangle Park, NC : National Institute of Environmental Health Sciences . NTPTR 363
  • 1999 . Huntington Life Sciences, A Range Finding Developmental/ Reproductive Toxicity Study of 1-Bromopropane in Rats Via Whole Body Inhalation Exposure , Study No. 98-4140 East Millstone, NJ Sponsored by BSOC. Available from the USEPA Docket A-91-42 Document X-B-65
  • WIL Research Laboratories, Inc. 2000 . An Inhalation Two Generation Reproductive Toxicity Study of 1-Bromopropane in Rats, WIL-380001 44805 Ashland, OH Sponsored by BSOC. Available from the USEPA Docket A-2001-07 Document II-D-10
  • Centre International de Toxicologie . 1995 . Micronucleus Test by Intraperitoneal Route in Mice. CIT Study No. 12122, Miserey, 27005 Evreux France Sponsored by Elf Autochem. Available from the USEPA Docket A-91-42 Document X-A-9
  • Maeng , S.H. and Yu , I.J. 1997 . Mutagenicity of 2-Bromopropane . Ind Health , 35 : 87 – 95 .
  • Jones , A.R. and Walsh , D.A. 1979 . The Oxidative Metabolism of 1-Bromopropane in the Rat . Xenobiotica , 12 : 763 – 772 .
  • Tachizawa , H. , McDonald , T.L. and Neal , R.A. 1982 . Rat Liver Microsomal Metabolism of PropyI HaIides . Mol Pharmacol , 22 : 745 – 751 .
  • Kaneko , T. , Kim , H.Y Wang , P-Y . 1997 . Partition Coefficients and Hepatic Metabolism in Vitro of 1- and 2-Bromopropanes . J Occup Health , 39 : 341 – 342 .
  • Kim , K.-W. , Kim , H.Y. Park , S.S. 1999 . Gender Differences in Activity and Induction of Hepatic Microsomal Cytochrome P-450 by 1-Broniopropane in Sprague-Dawley Rats . J Biochem Molec Bio , 32 : 232 – 238 .
  • Kim , Y. , Jung , K. Hwang , T. 1996 . Heniatopoietic and Reproductive Hazards of Korean Electronic Workers Exposed to Solvents Containing 2-Broniopropane . Scand J Work Environ Health , 22 : 287 – 291 .
  • Park , J.-S. , Kim , Y. Park , D.-W. 1997 . An Outbreak of Heniatopoietic and Reproductive Disorders Due to Solvents Containing 2-Broniopropane in an Electronic Factory in South Korea: Epidemiological Survey . J Occup Health , 39 : 138 – 143 .
  • Kim , Y. , Park , J. and Moon , Y . 1999 . Heniatopoietic and Reproductive Toxicity of Bromopropane. a Recently Introduced Substitute for ChIorofluorocarbons . Toxicol Lett , 108 : 303 – 313 .
  • Koh , J.-M , Kim , Ch.-H. Hong , S.-K. 1998 . Primary Ovarian Failure Caused by a Solvent Containing 2-Bromopropane . Eur J Endocrin , 138 : 554 – 556 .
  • Ichihara , G. , Ding , X. Yu , X. 1999 . Occupational Health Survey on Workers Exposed to 2-Bromopropane at Low Concentrations . Am J Indus Med , 35 : 523 – 531 .
  • NIOSH . 2000 . HETA 98-0153 , Morresville, NC : Study done at Custom Products. Inc. . (Chris Rhea). Department of Health and Human Services, National Institute for Occupational Safety & Health, Cincinnati. OH
  • Yu , X. , Ichihara , G. Kitoh , J. 1999 . Effect of Inhalation Exposure to 2-Bromopropane on the Nervous System in Rats . Toxicology , 135 : 87 – 93 .
  • Ichihara , G. , Asaeda , N. Kumazawa , T. 1997 . Testicular and Hematopoietic Toxicity of 2-Broniopropane. a Substitute for Ozone Layer-Depleting Chlorofluorocarbons . J Occup Health , 39 : 57 – 63 .
  • Kamijinia , M. , Ichihara , G. Kotoh , J. 1997 . Ovarian Toxicity of 2-Broniopropane in the Non-Pregnant Female Rat . J Occup Health , 39 : 144 – 149 .
  • Roznian , K.K. and Doull , J. 2000 . Dose and Time as Variables of Toxicity . Toxicology , 144 : 169 – 178 .
  • Rozman , K.K. and Doull , J. 2001 . The Role of Time as a Quantifi-able Variable of Toxicity and the Experimental Conditions When Haber's c x t Product Can Be Observed: Implications for Therapeutics . J Pharmacol Exp Ther , 296 : 663 – 668 .
  • Rozman , K.K. 2000 . “ Approaches for Using Toxicokinetic Information in Assessing Risk to Deployed U.S. Forces ” . In Strategies to Protect the Health of Deployed U.S. Forces , 113 – 149 . Washington, DC : National Academy Press .
  • Winthrobe , M.M. and Lee , G.R. 1974 . “ Hematologic Alterations ” . In Harrison's Principles of Internal Medicine, , 7th ed. , Edited by: Winthrobe , M.M. 229 New York : McGraw-Hill .
  • Storm , J.E. and Rozman , K.K. 1997 . Derivation of an Occupational Exposure Limit (OEL) for Methylene Chloride Based on Acute CNS Effects and Relative Potency Analysis . Regul Toxicol Pharmacol , 27 : 240 – 255 .

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