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Original Articles

Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs

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REFERENCES

  • Rosoamanana R , Darcel N , Fromentin G , Tomé D . Nutrient sensing and signaling by the gut . Proc Nutr Society 2012 ; 71 : 446 – 455 .
  • Ichimura A , Hirasawa A , Hara T , Tsujimoto G . Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis . Prostaglandins Other Lipid Mediat 2009 ; 89 : 82 – 88 .
  • Oh DY , Talukdar S , et al. . GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects . Cell 2010 ; 142 : 687 – 698 .
  • Miyauchi S , Hirasawa A , et al. . Distribution and regulation of protein expression of the free fatty acid receptor GPR120 . Naunyn Schmiedebergs Arch Pharmacol 2009 ; 379 : 427 – 434 .
  • Colombo M , Trevisi P , Gandolfi G , Bosi P . Assessment of the presence of chemosensing receptors based on bitter and fat taste in the gastrointestinal tract of young pig . J Anim Sci 2012 ; 90 ( Suppl 4 ): 128 – 130 .
  • Hirasawa A , Tsumaya K , et al. . Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120 . Nat Med 2005 ; 11 : 90 – 94 .
  • Fredborg M , Theil PK , Jensen BB , Purup S . G protein-coupled receptor120 (GPR120) transcription in intestinal epithelial cells is significantly affected by bacteria belonging to the Bacteroides, Proteobacteria, and Firmicutes phyla . J Anim Sci 2012 ; 90 ( Suppl 4 ): 10 – 12 .
  • Ichimura A , Hirasawa A , et al. . Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human . Nature 2012 ; 483 : 350 – 354 .
  • Waguri T , Goda T , Kasezawa N , Yamakawa-Kobayashi K . The combined effects of genetic variations in the GPR120 gene and dietary fat intake on obesity risk . Biomed Res 2013 ; 34 : 69 – 74 .
  • Fontanesi L , Bertolini F , Dall'Olio S , Buttazzoni L , Gallo M , Russo V . Analysis of association between the MUC4 g.8227C>G polymorphism and production traits in Italian heavy pigs using a selective genotyping approach . Anim Biotechnol 2012 ; 23 : 147 – 155 .
  • Fontanesi L , Bertolini F , et al. . Polymorphisms in an obesity-related gene (PCSK1) are associated with fat deposition and production traits in Italian heavy pigs . Animal 2012 ; 6 : 1913 – 1924 .
  • Fontanesi L , Galimberti G , et al. . Identification and association analysis of several hundred single nucleotide polymorphisms within candidate genes for back fat thickness in Italian Large White pigs using a selective genotyping approach . J Anim Sci 2012 ; 90 : 2450 – 2464 .
  • Fontanesi L , Schiavo G , et al. . A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes . BMC Genomics 2012 ; 13 : 583 .
  • Fontanesi L , Schiavo G , Galimberti G , Calò DG , Russo V . A genomewide association study for average daily gain in Italian Large White pigs . J Anim Sci 2014 ; 92 : 1385 – 1394 .
  • Rothberg JM , Hinz W , et al. . An integrated semiconductor device enabling non-optical genome sequencing . Nature 2011 ; 475 : 348 – 352 .
  • Kumar A , Wong AK , Tizard ML , Moore RJ , Lefèvre C . miRNA_Targets: a database for miRNA target predictions in coding and non-coding regions of mRNAs . Genomics 2012 ; 100 : 352 – 356 .
  • Li M , Xia Y , et al. . MicroRNAome of porcine pre- and postnatal development . PLoS One 2010 ; 5 : e11541 .
  • Chen X , Listman JB , Slack FJ , Gelernter J , Zhao H . Biases and errors on allele frequency estimation and disease association tests of next-generation sequencing of pooled samples . Genet Epidemiol 2012 ; 36 : 549 – 560 .
  • Hu ZL , Park CA , Wu XL , Reecy JM . Animal QTLdb: an improved database tool for livestock animal QTL/association data dissemination in the post-genome era . Nucleic Acids Res 2013 ; 41 ( Database issue ): D871 – D879 .
  • Miyauchi S , Hirasawa A , Ichimura A , Hara T , Tsujimoto G . New frontiers in gut nutrient sensor research: free fatty acid sensing in the gastrointestinal tract . J Pharmacol Sci 2010 ; 112 : 19 – 24 .

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