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Original Articles

Novel Mutation in Exon 1 of the BMP15 Gene and its Association with Reproduction Traits in Sheep

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References

  • Abdoli R, Zamani P, Deljou A, Rezvan H. Association of BMPR-1B and GDF9 genes polymorphisms and secondary protein structure changes with reproduction traits in Mehraban ewes. Gene 2013; 524:296–303.
  • Davis GHz. Fecundity genes in sheep. Anim Reprod Sci 2004; 82–83:247–253.
  • Davis GH. Major genes affecting ovulation rate in sheep. Genet Sel Evol 2005; 37(suppl1):S11–S23.
  • Galloway SM, McNatty KP, Cambridge LM, et al. Mutations in an oocyte derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet 2000; 25:279–283.
  • Hanrahan JP, Gregan SM, Mulsant P, et al. Mutations in the genes for oocyte derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries). Biol Reprod 2004; 70:900–909.
  • Bodin L. Di, Pasquale E, Fabre S, et al. A novel mutation in the bone morphogenetic protein 15 gene causing defective protein secretion is associated with both increased ovulation rate and sterility in Lacaune sheep. J Endocrinol 2007; 148:393–400.
  • McNatty KP, Galloway SM, Wilson T, et al. Physiological effects of major genes affecting ovulation rate in sheep. Genet Sel Evol 2005; 37:S25–S38.
  • Martinez-Royo A, Jurado JJ, Smulders JP, et al. A deletion in the bone morphogenetic protein 15 gene causes sterility and increased prolificacy in Rasa Aragonesa sheep. Anim Genet 2008; 39:294–297.
  • Davis GH, Balakrishnan L, Ross IK, et al. Investigation of the Booroola (FecB) and Inverdale (FecXI) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries. Anim Reprod Sci 2006; 92:87–96.
  • Kumar S, Mishra AK, Koite AP, Dash SK, Karim SK. Screening for Booroola (FecB) and Galway (FecXG) mutations in Indian sheep. Small Rumin Res 2008; 80:57–61.
  • Guan F, Shou-Reu L, Shi GQ, Yang LG. Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development. Anim Reprod Sci 2007; 99:44–52.
  • Barzegari A, Atashpaz S, Ghabili K, Nemati Z, Rustaci M, Azarbaijani R. Polymorphisms in GDF9 and BMP15 associated with fertility and ovulation rate in Moghani and Ghezel sheep in Iran. Reprod Domest Anim 2010; 45:666–669.
  • Moradband F, Rahim i G, Gholizadeh M. Association of polymorphism in fecundity genes of GDF9, BMP15 and BMPR-1B with litter size in Iranian Baluchi sheep. Asian Australas J Anim 2011; 24:1179–1183.
  • Jamshidi R, Kasiriyan MM, Hafezeyan H. Application of PCR-RFLP technique to determine BMP15 gene polymorphism in Sangsari sheep breed of Iran. Anim Veterinary 2009; 8:1906–1910.
  • Zamani P, Nadri S, Saffaripour R, Ahmadi A, Dashti F, Abdoli R. A new mutation in exon 2 of the bone morphogenetic protein 15 gene is associated with increase in prolificacy of Mehraban and Lori sheep. Trop Anim Health Prod 2015; 47:855–860.
  • Rozen S, Skaletsky HJ. Primer 3. 1998; Available at http://www.genome.wi.mit.edu/genomesoftware/otherprimer3.html.
  • SAS Institute. 2004; Users guide version 9.1: Statistics SAS Institute, Cary, NC.
  • Falconer DS, Mackay TFC. Introduction to quantitative genetics, 4th ed. Longmans Green, UK; 1996.
  • Bodin L, SanCristobal M, Lecerf F, et al. Segregation of a major gene influencing ovulation in progeny of Lacaune meat sheep. Genet Sel Evol 2002; 34:447–464.
  • Monteagudo LV, Ponz R, Tejedor MT, Lavina A, Sierra I. A 17 bp deletion in the Bone Morphogenetic Protein 15 (BMP15) gene is associated to increased prolificacy in the Rasa Aragonesa sheep breed. Anim Reprod Sci 2009; 110:139–146.
  • Zeder MA. Animal domestication in the Zagros: a review of past and current research. Paléorient 1999; 25:2, 11–26.

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