A 21-bp indel within the LLGL1 gene is significantly associated with litter size in goat

References

• Wang X, Yang Q, Wang K, et al. Two strongly linked single nucleotide polymorphisms (Q320P and V397I) in GDF9 gene are associated with litter size in cashmere goats. Theriogenology. 2019;125:115–121.
   PubMed Web of Science ®Google Scholar
• Yang Q, Yan H, Li J, et al. A novel 14-bp duplicated deletion within goat GHR gene is significantly associated with growth traits and litter size. Anim Genet. 2017;48:499–500.
   PubMed Web of Science ®Google Scholar
• Gregersen VR, Sorensen KK, Christensen OF, et al. Identification of QTL for dorso-caudal chronic pleuritis in 12 crossbred porcine families. Anim Genet. 2010;41(5):509–514.
   PubMed Web of Science ®Google Scholar
• Lu P, Feng X, Zhou JS, Liu XB, Chen QX, Li M. Identification and analysis of a 5-bp indel of a porcine BMP7 gene promoter. Genet Mol Res. 2014;13(2):4326–4335.
   PubMed Web of Science ®Google Scholar
• Baek KH. The first oncogene in Drosophila melanogaster. Mutat Res. 1999;436(2):131–136.
   PubMed Web of Science ®Google Scholar
• Bilder D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Develop. 2004;18:1909–1925.
   PubMed Web of Science ®Google Scholar
• Lehman K, Rossi G, Adamo JE, Brennwald P. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol. 1999;146:125–140.
   PubMed Web of Science ®Google Scholar
• Musch A, Cohen D, Yeaman C, Nelson WJ, Rodriguez-Boulan E, Brennwald PJ. Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells. MBoC. 2002;13:158–168.
   Google Scholar
• Yamanaka T, Horikoshi Y, Sugiyama Y, et al. Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity. Curr Biol. 2003;13(9):734–743.
   PubMed Web of Science ®Google Scholar
• Zhang X, Wang P, Gangar A, et al. Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol. 2005;170(2):273–283.
   PubMed Web of Science ®Google Scholar
• Grifoni D, Garoia F, Schimanski CC, et al. The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo. Oncogene. 2004;23(53):8688–8694.
   PubMed Web of Science ®Google Scholar
• Kim YK, Kim YS, Chung HM, Baek KH. Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes. Oncol Rep. 2004;12:1105–1108.
   PubMed Web of Science ®Google Scholar
• Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science. 2005;307(5715):1603–1609.
   PubMed Web of Science ®Google Scholar
• Dollar GL, Weber U, Mlodzik M, Sokol SY. Regulation of lethal giant larvae by Dishevelled. Nature. 2005;437(7063):1376–1380.
   PubMed Web of Science ®Google Scholar
• Vasioukhin V. Lethal giant puzzle of Lgl. Dev Neurosci. 2006;28(1–2):13–24.
   PubMed Web of Science ®Google Scholar
• Lai FN, Zhai HL, Cheng M, et al. Whole-genome scanning for the litter size trait associated genes and SNPs under selection in dairy goat (Capra hircus). Sci Rep. 2016;6(1):38096.
   PubMedGoogle Scholar
• Wang X, Yang Q, Wang K, et al. A novel 12-bp indel polymorphism within the GDF9 gene is significantly associated with litter size and growth traits in goats. Anim Genet. 2017;48(6):735–736.
   PubMed Web of Science ®Google Scholar
• Aljanabi SM, Martinez I. Universal and rapid salt-extraction of high quality genomic DNA for PCR-based techniques. Nucl Acids Res. 1997;25(22):4692–4693.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Cui W, Yang H, et al. A novel missense mutation (L280V) within POU1F1 gene strongly affects litter size and growth traits in goat. Theriogenology. 2019;135:198–203.
   PubMed Web of Science ®Google Scholar
• Kang Z, Jiang E, Wang K, et al. Goat membrane associated ring-CH-type finger 1 (MARCH1) mRNA expression and association with litter size. Theriogenology. 2019;128:8–16.
   PubMed Web of Science ®Google Scholar
• Chen M, Wang J, Liu N, et al. Pig SOX9: expression profiles of Sertoli cell (SCs) and a functional 18 bp indel affecting testis weight. Theriogenology. 2019;138:94–101.
   PubMed Web of Science ®Google Scholar
• Yang Q, Zhang S, Li J, et al. Development of a touch-down multiplex PCR method for simultaneously rapidly detecting three novel insertion/deletions (indels) within one gene: an example for goat GHR gene. Anim Biotechnol. 2019;30(4):366–371.
   PubMed Web of Science ®Google Scholar
• Cui Y, Yan H, Wang K, et al. Insertion/deletion within the KDM6A gene is significantly associated with litter size in goat. Front Genet. 2018;9:91.
   PubMed Web of Science ®Google Scholar
• Kang Z, Zhang S, He L, et al. A 14-bp functional deletion within the CMTM2 gene is significantly associated with litter size in goat. Theriogenology. 2019;139:49–57.
   PubMed Web of Science ®Google Scholar
• Chen L, Jensik PJ, Alaimo JT, et al. Functional analysis of novel DEAF1 variants identified through clinical exome sequencing expands DEAF1-associated neurodevelopmental disorder (DAND) phenotype. Hum Mutat. 2017;38(12):1774–1785.
   PubMed Web of Science ®Google Scholar
• Huggenvik JI, Michelson RJ, Collard MW, Ziemba AJ, Gurley P, Mowen KA. Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein. Mol Endocrinol. 1998;12(10):1619–1639.
   PubMedGoogle Scholar
• Chen M, Yan H, Wang K, et al. Goat SPEF2: Expression profile, indel variants identification and association analysis with litter size. Theriogenology. 2019;139:147–155.
   PubMed Web of Science ®Google Scholar
• Wang Z, Zhang X, Jiang E, et al., 2019. InDels within Caprine IGF2BP1 intron 2 and the 3’-untranslated regions are associated with goat growth traits. Anim Genet. doi:10.1111/age.12871
   Web of Science ®Google Scholar